Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(647 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(3.027 produtos)
- BACE(37 produtos)
- Beta Amilóide(230 produtos)
- CaMK(73 produtos)
- COX(602 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(373 produtos)
- Gama-secretase(62 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(41 produtos)
- Receptor opioide(327 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5639 produtos de "Neurociência"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
C2-8
CAS:C2-8 inhibits polyQ aggregation, IC50=25 μM (HDQ51), 0.05 μM (PC12 cells), reduces neurodegeneration in Huntington's models.Fórmula:C19H14Br2N2O3SCor e Forma:SolidPeso molecular:510.2Rovalpituzumab MMAE
Rovalpituzumab-MMAE (Anti-DLL3 Reference Antibody), produced in CHO cells, consists of a huIgG1 heavy chain and a hukappa light chain. The molecular weight of this antibody is predicted to be 145.02 kDa.Cor e Forma:LiquidPeso molecular:145 kDaTC-2559 difumarate
CAS:TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.Fórmula:C20H26N2O9Cor e Forma:SolidPeso molecular:438.43CHF-5022
CAS:CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Fórmula:C17H12F4O2Cor e Forma:SolidPeso molecular:324.27Histamine & Melatonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS
Cor e Forma:Odour SolidAChE-IN-45
AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant andCor e Forma:Odour SolidOrexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Fórmula:C154H247N47O46S4Cor e Forma:SolidPeso molecular:3621.15Trivalent GalNAc-DBCO
CAS:Trivalent GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Trivalent GalNAc-DBCO undergoes strain-promoted alkyne–azide cycloaddition (SPAAC) reactions with azide-containing molecules without the need for copper catalysis. Trivalent GalNAc-DBCO binds specifically to the asialoglycoprotein receptor (ASGPR), thereby directing conjugated molecules into hepatocytes for lysosomal degradation through receptor-mediated endocytosis. Trivalent GalNAc-DBCO is extensively applied in studies of liver-targeted drug delivery, targeted degradation strategies, and hepatocyte-specific molecular engineering.Fórmula:C91H144N12O34Pureza:96.33%Peso molecular:1950.18Anagyrine hydrochloride
CAS:Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.Fórmula:C15H21ClN2OCor e Forma:SolidPeso molecular:280.79Minaprine
CAS:Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.38I2-IRs ligand-1
I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.Fórmula:C21H23ClFN2O4PCor e Forma:SolidPeso molecular:452.84MK-0969
CAS:MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.Fórmula:C24H30F2N4O2Cor e Forma:SolidPeso molecular:444.52β-Amyloid (1-20)
CAS:This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.Fórmula:C113H157N31O32Pureza:98%Cor e Forma:SolidPeso molecular:2461.7Sandaracopimaric acid
CAS:Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Fórmula:C20H30O2Cor e Forma:SolidPeso molecular:302.45β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFórmula:C57H83N15O11Pureza:98%Cor e Forma:SolidPeso molecular:1154.36ACG548B
CAS:ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.Fórmula:C38H34Br2Cl2N4Cor e Forma:SolidPeso molecular:777.43Small Cardioactive Peptide B (SCPB)
CAS:SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).Fórmula:C52H80N14O11S2Pureza:98%Cor e Forma:SolidPeso molecular:1141.41Substance P(1-4) Acetate
Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.Fórmula:C24H44N8O7Pureza:99.84%Cor e Forma:SolidPeso molecular:556.66BMS-906024
CAS:BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.Fórmula:C26H26F6N4O3Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:556.5Palonosetron N-oxide
CAS:Palonosetron N-oxide: metabolite and potential impurity of 5-HT3 antagonist palonosetron; forms under oxidative stress.Fórmula:C19H24N2O2Cor e Forma:SolidPeso molecular:312.413
