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Neurociência

Neurociência

Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.

Subcategorias de "Neurociência"

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Foram encontrados 5634 produtos de "Neurociência"

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  • ALEPH hydrochloride

    CAS:
    ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.
    Fórmula:C12H20ClNO2S
    Cor e Forma:Solid
    Peso molecular:277.81

    Ref: TM-T203157

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  • ECPLA

    CAS:
    ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.
    Fórmula:C21H25N3O
    Cor e Forma:Solid
    Peso molecular:335.44

    Ref: TM-T203569

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  • Ethylpropyltryptamine

    CAS:
    Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.
    Fórmula:C15H22N2
    Cor e Forma:Solid
    Peso molecular:230.35

    Ref: TM-T203137

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  • 4-Hydroxy MET

    CAS:
    4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.
    Fórmula:C13H18N2O
    Cor e Forma:Solid
    Peso molecular:218.3

    Ref: TM-T203151

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  • 4-Chloromethamphetamine hydrochloride

    CAS:
    4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.
    Fórmula:C10H15Cl2N
    Cor e Forma:Solid
    Peso molecular:220.14

    Ref: TM-T203542

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  • 4-fluoro MBZP

    CAS:
    4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.
    Fórmula:C12H17FN2
    Cor e Forma:Solid
    Peso molecular:208.28

    Ref: TM-T203276

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  • 5-HT2C agonist-4

    CAS:
    Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.
    Fórmula:C24H25N5O
    Cor e Forma:Solid
    Peso molecular:399.49

    Ref: TM-T203570

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  • DOAM

    CAS:
    DOAM is an antagonist of the 5-HT2 receptor.
    Fórmula:C16H27NO2
    Cor e Forma:Solid
    Peso molecular:265.39

    Ref: TM-T203364

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  • 4-Methoxyphenyl isothiocyanate

    CAS:
    4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.
    Fórmula:C8H7NOS
    Cor e Forma:Solid
    Peso molecular:165.21

    Ref: TM-T203259

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  • (1S,3R)-3-Aminocyclopentane carboxylic acid

    CAS:
    (1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.
    Fórmula:C6H11NO2
    Cor e Forma:Solid
    Peso molecular:129.16

    Ref: TM-T203289

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  • Triazolomethylindole-3-acetic acid

    CAS:
    Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.
    Fórmula:C13H12N4O2
    Cor e Forma:Solid
    Peso molecular:256.26

    Ref: TM-T203624

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  • 2-Methyl-N,N-dimethyltryptamine

    CAS:
    2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.
    Fórmula:C13H18N2
    Cor e Forma:Solid
    Peso molecular:202.3

    Ref: TM-T203691

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  • Cannabidiolic acid methyl ester

    CAS:
    Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.
    Fórmula:C23H32O4
    Cor e Forma:Solid
    Peso molecular:372.5

    Ref: TM-T203571

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  • 5-HT2A receptor agonist-5

    CAS:
    5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.
    Fórmula:C23H29N3O
    Cor e Forma:Solid
    Peso molecular:363.5

    Ref: TM-T203649

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  • Paynantheine

    CAS:
    Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.
    Fórmula:C23H28N2O4
    Cor e Forma:Solid
    Peso molecular:396.48

    Ref: TM-T203202

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  • Nitrazolam

    CAS:
    Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.
    Fórmula:C17H13N5O2
    Cor e Forma:Solid
    Peso molecular:319.32

    Ref: TM-T203627

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  • 1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester

    CAS:

    Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。

    Fórmula:C26H34N2O7
    Pureza:99.44%
    Cor e Forma:Soild
    Peso molecular:486.56

    Ref: TM-T67751

    1mg
    313,00€
    5mg
    758,00€
    10mg
    1.035,00€
    25mg
    1.568,00€
    50mg
    2.118,00€
    100mg
    2.783,00€
  • (S)-3,4-DCPG

    CAS:
    (S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).
    Fórmula:C10H9NO6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:239.18

    Ref: TM-T23288

    1mg
    105,00€
    5mg
    388,00€
    10mg
    650,00€
  • AC1-IN-1

    CAS:

    AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).

    Fórmula:C18H18FN5O2
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:355.37

    Ref: TM-T60003

    1mg
    90,00€
    5mg
    188,00€
    10mg
    316,00€
    25mg
    512,00€
    50mg
    702,00€
    100mg
    940,00€
    500mg
    1.872,00€
  • TAT-CN21 (scrambled)


    TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).
    Cor e Forma:Odour Solid

    Ref: TM-TP3242

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