Neurociência
Os inibidores de neurociência são compostos projetados para modular a atividade de proteínas, enzimas ou receptores específicos no sistema nervoso. Esses inibidores são cruciais para estudar os mecanismos moleculares subjacentes à função neural, transmissão sináptica e doenças neurodegenerativas. Ao direcionar receptores de neurotransmissores, canais iônicos e vias de sinalização, os inibidores de neurociência ajudam na exploração da função cerebral e no desenvolvimento de estratégias terapêuticas para distúrbios neurológicos como Alzheimer, Parkinson e epilepsia. Na CymitQuimica, oferecemos uma ampla gama de inibidores de neurociência de alta qualidade para apoiar sua pesquisa em neurobiologia, neurofarmacologia e ciências cognitivas.
Subcategorias de "Neurociência"
- Receptor 5-HT(1.025 produtos)
- ACK(1 produtos)
- AChR(641 produtos)
- ATP Citrato Liase(17 produtos)
- Receptor adrenérgico(2.998 produtos)
- BACE(37 produtos)
- Beta Amilóide(217 produtos)
- CaMK(73 produtos)
- COX(598 produtos)
- Receptor de Dopamina(445 produtos)
- Receptor GABA(370 produtos)
- Gama-secretase(57 produtos)
- GluR(265 produtos)
- GlyT(26 produtos)
- Receptor de Histamina(385 produtos)
- LRRK2(43 produtos)
- Receptor de Melatonina(26 produtos)
- NMDAR(10 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(325 produtos)
Exibir 12 mais subcategorias
Foram encontrados 5447 produtos de "Neurociência"
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MAO-B-IN-38
MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.Fórmula:C14H17FN4O2S3Cor e Forma:SolidPeso molecular:388.504TMPH
CAS:TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.Fórmula:C16H31NO2Pureza:99.78%Cor e Forma:SoildPeso molecular:269.42Ref: TM-T60080
2mg35,00€5mg55,00€10mg84,00€25mg133,00€50mg205,00€100mg301,00€200mg425,00€1mL*10mM (DMSO)54,00€TIP 39, Tuberoinfundibular Neuropeptide
CAS:TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.Fórmula:C202H325N61O54SPureza:98%Cor e Forma:SolidPeso molecular:4504.2(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS:(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Fórmula:C6H11NO2Cor e Forma:SolidPeso molecular:129.16M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Cor e Forma:Odour SolidCalmodulin Binding Peptide 1
CAS:Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Fórmula:C231H373N69O70S2Pureza:98%Cor e Forma:SolidPeso molecular:5301.1JH-XII-03-02
CAS:JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PDFórmula:C43H51N9O10Pureza:98%Cor e Forma:SolidPeso molecular:853.92Pep63
CAS:Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Fórmula:C51H87N17O13Cor e Forma:SolidPeso molecular:1146.34β-Amyloid (12-20)
CAS:β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFórmula:C57H83N15O11Pureza:98%Cor e Forma:SolidPeso molecular:1154.365-HT1AR agonist 2
5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.Fórmula:C31H31N5O3Cor e Forma:SolidPeso molecular:521.61Selank
CAS:Selank is a synthetic analog of tuftsin.Fórmula:C33H57N11O9Pureza:98%Cor e Forma:SolidPeso molecular:751.87Orexin B, rat, mouse
CAS:Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.Fórmula:C126H215N45O34SPureza:98%Cor e Forma:SolidPeso molecular:2936.454-Methoxyphenyl isothiocyanate
CAS:4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.Fórmula:C8H7NOSCor e Forma:SolidPeso molecular:165.21HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.Fórmula:C35H43Cl2F2N5O4Cor e Forma:SolidPeso molecular:706.65(Rac)-Oleoylcarnitine
CAS:(Rac)-Oleoylcarnitine, an endogenous acylcarnitine, acts as a potential non-competitive inhibitor of glycine transporter 2 (GLYT2) and can be used as a pain suppressant.Fórmula:C25H47NO4Peso molecular:425.65DSP-1053
CAS:Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.Fórmula:C26H32BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:502.44Nemifitide diTFA
CAS:Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.Fórmula:C37H45F7N10O10Pureza:99.78% - 99.84%Cor e Forma:SolidPeso molecular:922.8EGLU
CAS:EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.Fórmula:C7H13NO4Pureza:99.98%Cor e Forma:SolidPeso molecular:175.18SB-269970 hydrochloride
CAS:SB-269970 hydrochloride (SB-269970A) , a hydrochloride salt form of SB-269970, is a 5-HT7 receptor antagonist (pKi of 8.3) and exhibits >50-fold selectivityFórmula:C18H28N2O3S·HClPureza:99.8%Cor e Forma:SolidPeso molecular:388.95Tolterodine L-Tartrate
CAS:Fórmula:C22H31NO·C4H6O6Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:475.58
