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Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

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Foram encontrados 1370 produtos de "Tirosina Quinase/Adaptador"

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  • WAY-270250
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    WAY-270250

    CAS:
    <p>WAY-270250 is an IGF-1R/SRC inhibitor.</p>
    Fórmula:C18H16N2O2
    Pureza:99.77%
    Cor e Forma:Soild
    Peso molecular:292.33

    Ref: TM-T77624

  • GIP (1-30) amide,human
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    GIP (1-30) amide,human

    CAS:
    <p>GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.</p>
    Fórmula:C162H240N40O47S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3531.94

    Ref: TM-TP1584

  • Varlitinib Tosylate
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    Varlitinib Tosylate

    CAS:
    <p>Varlitinib Tosylate is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2).</p>
    Fórmula:C36H35ClN6O8S3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:811.34

    Ref: TM-T20954

  • Logotipo do CymitQuimica
    Targetmol
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    EGFR-IN-42

    <p>EGFR-IN-42 (17b) is a potent EGFR inhibitor with nanomolar efficacy, merging tamoxifen/endoxifen and gefitinib, exhibiting enhanced anti-cancer action.</p>
    Fórmula:C49H53ClFN5O5
    Cor e Forma:Solid
    Peso molecular:846.43

    Ref: TM-T74457

  • Logotipo do CymitQuimica
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    Macupatide

    CAS:
    <p>Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.</p>
    Cor e Forma:Solid

    Ref: TM-TP3263

  • DA-JC4
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    DA-JC4

    CAS:
    <p>DA-JC4: dual GLP-1/GIP agonist, for neurological disease research and insulin pathway studies.</p>
    Fórmula:C225H346N56O65
    Cor e Forma:Solid
    Peso molecular:4875.49

    Ref: TM-T37599

  • Logotipo do CymitQuimica
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    Cixutumumab

    CAS:
    <p>Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor activation, impeding</p>
    Pureza:98.5% (SDS-PAGE); 97.5% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.5% (SEC-HPLC)
    Cor e Forma:Liquid

    Ref: TM-T78279

  • MS9427
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    MS9427

    CAS:
    <p>MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.</p>
    Fórmula:C48H58ClFN8O12
    Cor e Forma:Solid
    Peso molecular:993.47

    Ref: TM-T74633

  • HER2/neu (654-662) GP2
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    HER2/neu (654-662) GP2

    CAS:
    <p>Phage display selected Affibody ligands for HER2/neu from a protein library based on a 58-residue Staphylococcal protein A Z domain.</p>
    Fórmula:C42H77N9O11
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:884.11

    Ref: TM-TP1583

  • CREBtide
    Targetmol
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    CREBtide

    CAS:
    <p>CREBtide is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).</p>
    Fórmula:C73H129N29O19
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1716.99

    Ref: TM-TP1876

  • KN1022
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    KN1022

    CAS:
    <p>KN1022 is an inhibitor of phosphorylation of platelet-derived growth factor (PDGF) receptor with IC50 of 0.26 μM.</p>
    Fórmula:C21H22N6O5
    Pureza:99.68%
    Cor e Forma:Soild
    Peso molecular:438.44

    Ref: TM-T60110

  • JAK 3 inhibitor IV
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    JAK 3 inhibitor IV

    CAS:
    <p>JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to</p>
    Fórmula:C16H19NO
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:241.33

    Ref: TM-T2460

  • ALKBH5-IN-5
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    ALKBH5-IN-5

    CAS:
    <p>ALKBH5-IN-5 is a highly selective, potent and covalently binding ALKBH5 inhibitor that alters m6A levels on mRNA, induces apoptosis, antitumo.</p>
    Fórmula:C13H13NO3
    Pureza:99.54%
    Cor e Forma:Soild
    Peso molecular:231.25

    Ref: TM-T203011

  • Logotipo do CymitQuimica
    Targetmol
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    FLT3-ITD-IN-2

    <p>FLT3-ITD-IN-2 (Compound A1) is an inhibitor of the FLT3-ITD kinase, exhibiting an IC50 of 2.12 nM. It effectively suppresses the proliferation of the FLT3-dependent human AML cell line MOLM-13, with an IC50 of 25.65 nM. FLT3-ITD-IN-2 demonstrates antitumor activity against acute myeloid leukemia.</p>
    Fórmula:C39H50N8O6
    Cor e Forma:Solid
    Peso molecular:726.86

    Ref: TM-T203046

  • Logotipo do CymitQuimica
    Targetmol
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    DSPE-PEG2000-GE11

    <p>DSPE-PEG2000-GE11 is a PEG compound composed of DSPE and an EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells that overexpress EGFR. DSPE-PEG2000-GE11 is utilized in drug delivery.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01177

  • PKG inhibitor peptide
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    PKG inhibitor peptide

    CAS:
    <p>PKG inhibitor; mimics H2B phosphorylation site; Ki=86mM; blocks synthetic substrates, not histone phosphorylation; stops PKA activity on histones.</p>
    Fórmula:C38H74N18O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:943.12

    Ref: TM-TP1903

  • KYL peptide
    Targetmol
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    KYL peptide

    CAS:
    <p>EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines &amp; LTP; long half-life (8-12h), neuroprotective.</p>
    Fórmula:C74H108N14O17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1465.75

    Ref: TM-TP1895

  • Gastric Inhibitory Peptide (1-42) (porcine) TFA
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    Gastric Inhibitory Peptide (1-42) (porcine) TFA

    <p>Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.</p>
    Fórmula:C225H342N60O66S·XCF3COOH
    Cor e Forma:Solid
    Peso molecular:4975.55

    Ref: TM-T83694

  • Tephrosin
    Targetmol
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    Tephrosin

    CAS:
    <p>Tephrosin induces degradation of of EGFR and ErbB2 by inducing internalization of the receptors, has potent antitumor activities.</p>
    Fórmula:C23H22O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:410.42

    Ref: TM-T13126

  • Logotipo do CymitQuimica
    Targetmol
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    PROTAC EGFR degrader 2

    <p>Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for NTR-responsive synthesis.</p>
    Fórmula:C58H72ClFN12O8S
    Cor e Forma:Solid
    Peso molecular:1151.78

    Ref: TM-T74333