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Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

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Foram encontrados 1357 produtos de "Tirosina Quinase/Adaptador"

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  • Kinase Inhibitor Library
    Targetmol
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    Kinase Inhibitor Library

    <p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>
    Cor e Forma:Odour Solid

    Ref: TM-L1600

  • LMTK3-IN-1
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    LMTK3-IN-1

    CAS:
    <p>Lmtk3-in-1 is a potent ATP-competitive lemur tyrosine kinase 3 (LMTK3) (Kd=2.5 μM) inhibitor that degrades LMTK3 through the ubiquitin proteasome pathway.</p>
    Fórmula:C18H11F3N4O
    Pureza:99.89%
    Cor e Forma:Soild
    Peso molecular:356.3

    Ref: TM-T77620

  • ZM 449829
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    ZM 449829

    CAS:
    <p>ZM 449829: Selective JAK3 inhibitor, binds to ATP site. pIC50: 6.8 for JAK3, others &lt; 5.0.</p>
    Fórmula:C13H10O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:182.222

    Ref: TM-T23564

  • Gastric Inhibitory Peptide (1-42) (porcine) TFA
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    Gastric Inhibitory Peptide (1-42) (porcine) TFA

    <p>Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.</p>
    Fórmula:C225H342N60O66S·XCF3COOH
    Cor e Forma:Solid
    Peso molecular:4975.55

    Ref: TM-T83694

  • Logotipo do CymitQuimica
    Targetmol
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    Otilimab

    CAS:
    <p>Otilimab, a humanized monoclonal antibody, blocks GM-CSF to reduce inflammation and may treat severe COVID-19 pneumonia.</p>
    Pureza:> 95%
    Cor e Forma:Liquid
    Peso molecular:142.22 kDa

    Ref: TM-T77125

  • IGF-I (24-41)
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    IGF-I (24-41)

    CAS:
    <p>IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.</p>
    Fórmula:C88H133N27O28
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2017.16

    Ref: TM-TP1124

  • Varlitinib Tosylate
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    Varlitinib Tosylate

    CAS:
    <p>Varlitinib Tosylate is a selective and potent inhibitor of ErbB1(EGFR) and ErbB2(HER2).</p>
    Fórmula:C36H35ClN6O8S3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:811.34

    Ref: TM-T20954

  • GNF2133
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    GNF2133

    CAS:
    <p>GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.</p>
    Fórmula:C24H30N6O2
    Pureza:98.51%
    Cor e Forma:Solid
    Peso molecular:434.53

    Ref: TM-T40187

  • BMS-599626 2HCL(714971-09-2 Free base)
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    BMS-599626 2HCL(714971-09-2 Free base)

    CAS:
    <p>BMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative.</p>
    Fórmula:C27H29Cl2FN8O3
    Pureza:99.11%
    Cor e Forma:Odour Solid
    Peso molecular:603.47

    Ref: TM-T2610L

  • BMS-599626
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    BMS-599626

    CAS:
    <p>BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.</p>
    Fórmula:C27H27FN8O3
    Pureza:98.73%
    Cor e Forma:Solid
    Peso molecular:530.55

    Ref: TM-T2610

  • Nuzefatide
    Targetmol
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    Nuzefatide

    CAS:
    <p>Nuzefatide is a peptide that binds to liver protein receptors.</p>
    Fórmula:C105H162N32O27S3
    Cor e Forma:Solid
    Peso molecular:2400.80

    Ref: TM-TP3269

  • Logotipo do CymitQuimica
    Targetmol
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    IBI-334

    <p>IBI-334 is a bispecific antibody targeting both B7-H3 and EGFR. It features an EGFR arm responsible for signal blocking, connected to a modified B7-H3 arm that ensures optimal affinity and binding. The antibody is afucosylated to enhance its antibody-dependent cellular cytotoxicity (ADCC) effects. IBI-334 is widely applicable in EGFR-driven solid tumors.</p>
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-802

  • Logotipo do CymitQuimica
    Targetmol
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    GIP (1-30) amide, porcine TFA

    <p>GIP (1-30) amide, porcine TFA: a full GIP receptor agonist, similar to natural GIP(1-42), stimulates insulin, mildly inhibits gastric acid.</p>
    Cor e Forma:Liquid

    Ref: TM-T37601

  • JAK1/2/3 Inhibitor 1
    Targetmol
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    JAK1/2/3 Inhibitor 1

    CAS:
    <p>JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell lines</p>
    Fórmula:C6H2Cl2N2S
    Pureza:99.32%
    Cor e Forma:Solid
    Peso molecular:205.06

    Ref: TM-T77504

  • EGFR-IN-76
    Targetmol
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    EGFR-IN-76

    CAS:
    <p>EGFR-IN-76 is a potent EGFR inhibitor.</p>
    Fórmula:C30H30ClFN6O2
    Pureza:97.02% - 97.72%
    Cor e Forma:Solid
    Peso molecular:561.05

    Ref: TM-T75120

  • Logotipo do CymitQuimica
    Targetmol
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    EGFR-IN-127

    <p>EGFR-IN-127 is an ATP-competitive inhibitor targeting EGFR, with IC50 values of 136.3 nM for EGFRdel19 and 161.2 nM for EGFRdel19/T790M/C797S. This compound holds potential for the study of non-small cell lung cancer (NSCLC).</p>
    Cor e Forma:Odour Solid

    Ref: TM-T200430

  • Logotipo do CymitQuimica
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    Lumretuzumab

    CAS:
    <p>Lumretuzumab (RG-7116) is a humanized anti-HER3 monoclonal antibody with antitumor activity.</p>
    Pureza:95.3% (SDS-PAGE); 96.4% (SEC-HPLC) - 95.3% (SDS-PAGE); 96.4% (SEC-HPLC)
    Cor e Forma:Liquid

    Ref: TM-T76818

  • Logotipo do CymitQuimica
    Targetmol
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    Insulin peglispro

    CAS:
    Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.
    Fórmula:C370H566N104O110S4
    Cor e Forma:Solid
    Peso molecular:8359.32

    Ref: TM-T76540

  • Logotipo do CymitQuimica
    Targetmol
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    MS9427 TFA

    <p>MS9427 TFA: PROTAC EGFR degrader, Kd 7.1 nM (WT), 4.3 nM (L858R), targets mutant EGFR, inhibits NSCLC cell growth, for cancer research.</p>
    Fórmula:C50H59ClF4N8O14
    Cor e Forma:Solid
    Peso molecular:1107.5

    Ref: TM-T74634

  • MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate
    Targetmol
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    MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate

    CAS:
    <p>MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate is a conjugate formed by linking MC-Val-Cit-PAB-Amide and TLR7 agonist 4, useful for cancer research.</p>
    Fórmula:C52H72N12O11
    Pureza:97.70%
    Cor e Forma:Solid
    Peso molecular:1041.2

    Ref: TM-T74468