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Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

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Foram encontrados 1342 produtos de "Tirosina Quinase/Adaptador"

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  • Logotipo do CymitQuimica
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    Kemptide Phospho-Ser5

    <p>Kemptide (Phospho-Ser5) is a phosphoreceptor peptide that is a specific substrate for camp-dependent protein kinase (PKA).</p>
    Fórmula:C32H62N13O12P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:851.89

    Ref: TM-TP1723

  • NBI-31772
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    NBI-31772

    CAS:
    <p>NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).</p>
    Fórmula:C17H11NO7
    Pureza:99.79%
    Cor e Forma:Solid
    Peso molecular:341.27

    Ref: TM-T8906

  • Logotipo do CymitQuimica
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    Timigutuzumab

    CAS:
    <p>Timigutuzumab (GEXMab73) is a humanized monoclonal antibody designed to target ErbB2, showing potential application in cancer research [1].</p>
    Cor e Forma:Liquid

    Ref: TM-T76977

  • Logotipo do CymitQuimica
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    Pertuzumab

    CAS:
    <p>Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2</p>
    Pureza:98.00%
    Cor e Forma:Liquid
    Peso molecular:148 kDa

    Ref: TM-T9909

  • SU 4981
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    SU 4981

    CAS:
    <p>SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.</p>
    Fórmula:C19H18N2O2
    Pureza:95.4%
    Cor e Forma:Soild
    Peso molecular:306.36

    Ref: TM-T60094

  • Logotipo do CymitQuimica
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    pYEEI

    <p>pYEEI, a tetrapeptide containing phosphotyrosine, binds to the SrcSH2 domain with a dissociation constant (Kd) of 100 nM and an inhibitory concentration (IC50) of 6.5 μM. This compound plays a crucial role in cancer research.</p>
    Fórmula:C25H36N3O14P
    Cor e Forma:Solid
    Peso molecular:633.54

    Ref: TM-TP2856

  • GIP, human
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    GIP, human

    CAS:
    <p>Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.</p>
    Fórmula:C226H338N60O66S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4983.6

    Ref: TM-TP2018

  • BI-4732
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    BI-4732

    CAS:
    <p>DL-Homocystine is a mutagen secreted by F. nucleatum.</p>
    Fórmula:C32H36N10O2
    Pureza:98.88%
    Cor e Forma:Solid
    Peso molecular:592.69

    Ref: TM-T85354

  • Herceptide
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    Herceptide

    CAS:
    <p>Herceptide (HER2-targeting peptide), a peptide that targets HER2, can be conjugated with the near-infrared fluorescent dye indocyanine green (ICG), facilitating the development of theranostic agents.</p>
    Fórmula:C76H110N22O23
    Cor e Forma:Solid
    Peso molecular:1699.82

    Ref: TM-TP2876

  • Logotipo do CymitQuimica
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    EGFR-IN-42

    <p>EGFR-IN-42 (17b) is a potent EGFR inhibitor with nanomolar efficacy, merging tamoxifen/endoxifen and gefitinib, exhibiting enhanced anti-cancer action.</p>
    Fórmula:C49H53ClFN5O5
    Cor e Forma:Solid
    Peso molecular:846.43

    Ref: TM-T74457

  • Logotipo do CymitQuimica
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    SOS1/EGFR-IN-2

    <p>SOS1/EGFR-IN-2 (Compound 4) functions as a dual inhibitor of SOS1 and EGFR, exhibiting IC50 values of 8.3 and 14.6 nM, respectively. It demonstrates significant antiproliferative effects on cancer cells harboring various KRAS mutations.</p>
    Fórmula:C25H29F3N4O3
    Cor e Forma:Solid
    Peso molecular:490.52

    Ref: TM-T200843

  • Logotipo do CymitQuimica
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    MS9427 TFA

    <p>MS9427 TFA: PROTAC EGFR degrader, Kd 7.1 nM (WT), 4.3 nM (L858R), targets mutant EGFR, inhibits NSCLC cell growth, for cancer research.</p>
    Fórmula:C50H59ClF4N8O14
    Cor e Forma:Solid
    Peso molecular:1107.5

    Ref: TM-T74634

  • Logotipo do CymitQuimica
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    Valanafusp alfa

    CAS:
    <p>Valanafusp alfa (AGT-181) is a fusion protein targeting HIR and IDUA for MPS I research.</p>
    Cor e Forma:Liquid

    Ref: TM-T76964

  • PKI(5-24)
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    PKI(5-24)

    CAS:
    <p>High affinity PKA inhibitor (Ki = 2.3 nM).</p>
    Fórmula:C76H129N31O28
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1925.057

    Ref: TM-TP1957

  • Logotipo do CymitQuimica
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    EGFR/PI3Kα-IN-1

    <p>EGFR/PI3Kα-IN-1 (compound 30k), a dual EGFR/PI3Kα inhibitor, exhibits potent activity with IC 50 values of 3.6 nM (EGFRL858R/T790M) and 30 nM (PI3Kα). It effectively inhibits tumor cell proliferation and demonstrates significant anticancer activity.</p>
    Fórmula:C50H49N11O5S
    Cor e Forma:Solid
    Peso molecular:916.06

    Ref: TM-T200282

  • Logotipo do CymitQuimica
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    EGFR-IN-162

    <p>EGFR-IN-162 (compound 20) is an effective EGFR inhibitor that enhances both early and late apoptosis (EGFR) as well as necrosis (necrosis). It shows potential for use in breast cancer research.</p>
    Fórmula:C27H31N3O2
    Cor e Forma:Solid
    Peso molecular:429.24163

    Ref: TM-T207511

  • Logotipo do CymitQuimica
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    EGFR-IN-128

    <p>EGFR-IN-128 (compound 28) is a potent and selective molecule targeting wild-type EGFREx20Ins, demonstrating therapeutic efficacy across various human xenograft models and capable of penetrating the blood-brain barrier in preclinical species.</p>
    Fórmula:C27H20N4O
    Cor e Forma:Solid
    Peso molecular:416.47

    Ref: TM-T201175

  • Logotipo do CymitQuimica
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    AVE1642

    <p>AVE1642 is a human IgG monoclonal antibody (mAb) that specifically targets CD221/IGF1R. It has the ability to slow the growth of tumor xenografts and extend the survival of tumor-bearing nude mice. AVE1642 is applicable in the study of advanced solid tumors. Recommended isotype control: HumanIgG1kappa, Isotype Control.</p>
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-1063

  • WAY-270360
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    WAY-270360

    CAS:
    <p>WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.</p>
    Fórmula:C22H19N3O3
    Pureza:98.05%
    Cor e Forma:Solid
    Peso molecular:373.4

    Ref: TM-T60064

  • PKG Substrate
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    PKG Substrate

    CAS:
    <p>PKG Substrate is selective for PKG, favors PKG Iα (Km=59µM) over PKG II (Km=305µM).</p>
    Fórmula:C35H67N17O11
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:902.01

    Ref: TM-TP1787