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Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

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Foram encontrados 1342 produtos de "Tirosina Quinase/Adaptador"

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  • Simotinib hydrochloride
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    Simotinib hydrochloride

    CAS:
    <p>Simotinib hydrochloride: selective oral EGFR inhibitor, IC50 19.9 nM, potent anticancer agent.</p>
    Fórmula:C25H27Cl2FN4O4
    Cor e Forma:Solid
    Peso molecular:537.41

    Ref: TM-T39019

  • H1-7 (histone H1 phosphorylation site), PKA Substrate
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    H1-7 (histone H1 phosphorylation site), PKA Substrate

    CAS:
    <p>H1-7 (histone H1 phosphorylation site), a synthetic polypeptide serving as a PKA substrate, demonstrates utility in PKA substrate applications [1] [2].</p>
    Fórmula:C31H58N14O9
    Cor e Forma:Solid
    Peso molecular:770.88

    Ref: TM-T76381

  • Logotipo do CymitQuimica
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    Insulin efsitora alfa

    CAS:
    <p>Insulin efsitora alfa(LY-3209590) is an IR agonist and a fusion protein that binds a novel single-chain insulin variant to the structural domain of human IgG Fc</p>
    Pureza:98.3% (SDS-PAGE); 98.1% (SEC-HPLC) - 98.3% (SDS-PAGE); 98.1% (SEC-HPLC)
    Cor e Forma:Liquid

    Ref: TM-T77037

  • Secretin, canine
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    Secretin, canine

    CAS:
    Secretin: endocrine hormone, increases bicarbonate-rich pancreatic fluid, regulates canine gastric functions via Src kinase pathway.
    Fórmula:C131H222N44O41
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:3069.43

    Ref: TM-TP1610

  • Kemptide
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    Kemptide

    CAS:
    <p>Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK).</p>
    Fórmula:C32H61N13O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:771.91

    Ref: TM-TP1351

  • EGFR-IN-140
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    EGFR-IN-140

    <p>EGFR-IN-140 (Compound 31) is an inhibitor of EGFR, effectively targeting both wild-type EGFR and the EGFRL858R/T790M/C797S mutant, with Ki values of 0.95 nM and 2.1 nM, respectively. Additionally, it inhibits EGFRdel19/T790M/C797S in Ba/F3 cells with an IC50 of 56.9 nM and demonstrates antitumor activity in mouse models.</p>
    Fórmula:C27H37FN8O2
    Cor e Forma:Solid
    Peso molecular:524.633

    Ref: TM-T204256

  • Logotipo do CymitQuimica
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    Gefitinib N-oxide hydrochloride

    <p>Gefitinib N-oxide hydrochloride is an N-oxide of EGFR inhibitor Gefitinib with IC50 of 2-37 nM.</p>
    Fórmula:C22H24ClFN4O41·5HCl
    Cor e Forma:Solid
    Peso molecular:517.59

    Ref: TM-T73627

  • cis-NVP-ADW742
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    cis-NVP-ADW742

    CAS:
    <p>NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, &gt;16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.</p>
    Fórmula:C28H31N5O
    Cor e Forma:Solid
    Peso molecular:453.59

    Ref: TM-T2107

  • Logotipo do CymitQuimica
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    YH32367

    <p>YH32367 (ABL105) is a bispecific antibody targeting HER2 and 4-1BB. It induces the secretion of IFN-γ, resulting in the death of tumor cells when co-cultured with hPBMC and HER2-expressing tumor cells. YH32367 demonstrates notable antitumor activity.</p>
    Cor e Forma:Odour Liquid

    Ref: TM-T9901A-800

  • Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
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    Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

    CAS:
    <p>Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.</p>
    Fórmula:C32H46N5O17P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:803.71

    Ref: TM-TP2085

  • Hck-IN-2
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    Hck-IN-2

    <p>Hck-IN-2 (Compound 8e) acts as an HCK inhibitor with demonstrated cytotoxic effects on tumor cells. It exhibits an IC50 of 19.58 μM for MDA-MB231 cells and 1.42 μM for MCF-7 cells. Additionally, Hck-IN-2 possesses antitumor activity.</p>
    Fórmula:C36H35FN6O10
    Cor e Forma:Solid
    Peso molecular:730.696

    Ref: TM-T205715

  • Herceptide
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    Herceptide

    CAS:
    <p>Herceptide (HER2-targeting peptide), a peptide that targets HER2, can be conjugated with the near-infrared fluorescent dye indocyanine green (ICG), facilitating the development of theranostic agents.</p>
    Fórmula:C76H110N22O23
    Cor e Forma:Solid
    Peso molecular:1699.82

    Ref: TM-TP2876

  • BMS-599626
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    BMS-599626

    CAS:
    <p>BMS-599626 (AC480) has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.</p>
    Fórmula:C27H27FN8O3
    Pureza:98.73%
    Cor e Forma:Solid
    Peso molecular:530.55

    Ref: TM-T2610

  • CLK1-IN-3
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    CLK1-IN-3

    CAS:
    <p>Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A.</p>
    Fórmula:C24H23FN6O
    Pureza:98.46% - 99.76%
    Cor e Forma:Soild
    Peso molecular:430.48

    Ref: TM-T72039

  • Logotipo do CymitQuimica
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    pYEEI

    <p>pYEEI, a tetrapeptide containing phosphotyrosine, binds to the SrcSH2 domain with a dissociation constant (Kd) of 100 nM and an inhibitory concentration (IC50) of 6.5 μM. This compound plays a crucial role in cancer research.</p>
    Fórmula:C25H36N3O14P
    Cor e Forma:Solid
    Peso molecular:633.54

    Ref: TM-TP2856

  • Logotipo do CymitQuimica
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    Macupatide

    CAS:
    Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.
    Cor e Forma:Solid

    Ref: TM-TP3263

  • Logotipo do CymitQuimica
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    Timigutuzumab

    CAS:
    <p>Timigutuzumab (GEXMab73) is a humanized monoclonal antibody designed to target ErbB2, showing potential application in cancer research [1].</p>
    Cor e Forma:Liquid

    Ref: TM-T76977

  • SU 4981
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    SU 4981

    CAS:
    <p>SU 4981 is an inhibitor of VEGFR and a modulator of tyrosine kinase activity.</p>
    Fórmula:C19H18N2O2
    Pureza:95.4%
    Cor e Forma:Soild
    Peso molecular:306.36

    Ref: TM-T60094

  • PF-04217903 phenolsulfonate
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    PF-04217903 phenolsulfonate

    CAS:
    <p>PF-04217903 phenolsulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).</p>
    Fórmula:C25H22N8O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:546.56

    Ref: TM-T12418

  • Acalabrutinib enantiomer
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    Acalabrutinib enantiomer

    CAS:
    <p>R-Acalabrutinib, a BTK inhibitor,enantiomer, is researched for cancer, autoimmune diseases, and inflammation.</p>
    Fórmula:C26H23N7O2
    Pureza:97.27%
    Cor e Forma:Solid
    Peso molecular:465.51

    Ref: TM-T67881