CymitQuimica logo
Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

Exibir 13 mais subcategorias

Foram encontrados 1370 produtos de "Tirosina Quinase/Adaptador"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • Ack1 inhibitor 2
    Targetmol
    + Info

    Ack1 inhibitor 2

    CAS:
    <p>Ack1 Inhibitor 2, also referred to as Example 259, effectively inhibits Ack1 with an IC50 value of 0.46 μM [1].</p>
    Fórmula:C23H23N5O2
    Cor e Forma:Solid
    Peso molecular:401.46

    Ref: TM-T85584

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Adimanebart

    CAS:
    <p>Amdokitug is a human-derived IgG1λ monoclonal antibody that acts as an inhibitor of MUSK.</p>
    Cor e Forma:Liquid

    Ref: TM-T9901A-866

  • PKG inhibitor peptide
    Targetmol
    + Info

    PKG inhibitor peptide

    CAS:
    <p>PKG inhibitor; mimics H2B phosphorylation site; Ki=86mM; blocks synthetic substrates, not histone phosphorylation; stops PKA activity on histones.</p>
    Fórmula:C38H74N18O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:943.12

    Ref: TM-TP1903

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    EGFR-IN-127

    <p>EGFR-IN-127 is an ATP-competitive inhibitor targeting EGFR, with IC50 values of 136.3 nM for EGFRdel19 and 161.2 nM for EGFRdel19/T790M/C797S. This compound holds potential for the study of non-small cell lung cancer (NSCLC).</p>
    Cor e Forma:Odour Solid

    Ref: TM-T200430

  • Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
    Targetmol
    + Info

    Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH

    CAS:
    <p>Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.</p>
    Fórmula:C32H46N5O17P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:803.71

    Ref: TM-TP2085

  • PKG Substrate
    Targetmol
    + Info

    PKG Substrate

    CAS:
    <p>PKG Substrate is selective for PKG, favors PKG Iα (Km=59µM) over PKG II (Km=305µM).</p>
    Fórmula:C35H67N17O11
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:902.01

    Ref: TM-TP1787

  • HER2/neu (654-662) GP2 acetate
    Targetmol
    + Info

    HER2/neu (654-662) GP2 acetate

    <p>GP2 acetate, from HER2 (654-662), triggers HLA-A2-restricted T cells to attack epithelial cancers.</p>
    Fórmula:C44H81N9O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:944.17

    Ref: TM-TP1583L

  • BI-4732
    Targetmol
    + Info

    BI-4732

    CAS:
    <p>DL-Homocystine is a mutagen secreted by F. nucleatum.</p>
    Fórmula:C32H36N10O2
    Pureza:98.88%
    Cor e Forma:Solid
    Peso molecular:592.69

    Ref: TM-T85354

  • PKA Inhibitor Fragment (6-22) amide TFA
    Targetmol
    + Info

    PKA Inhibitor Fragment (6-22) amide TFA

    <p>PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of cAMP-dependent protein kinase A (PKA).</p>
    Fórmula:C82H131F3N28O26
    Pureza:99.61% - 99.87%
    Cor e Forma:Solid
    Peso molecular:1982.08

    Ref: TM-T75888

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    DDR Inhibitor 2

    <p>DDR Inhibitor 2 (compound 5a) is a potent inhibitor of the discoidin domain receptor (DDR) with an IC50 value of 0.125 μM, and it is applicable in fibrotic disease research.</p>
    Fórmula:C21H23N7O
    Cor e Forma:Solid
    Peso molecular:389.19641

    Ref: TM-T207238

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    EGFR-IN-124

    <p>EGFR-IN-124 (compound 10A) is an EGFR inhibitor with an IC50 value of 0.54 μM, utilized in cancer research.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T200720

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Mecbotamab vedotin

    CAS:
    <p>Mecbotamab vedotin (BA301) is an inhibitory IgG1 antibody that targets human tyrosine kinase receptor AXL and the humanized murine monoclonal BA301 γ1 chain. It can be utilized in the preparation of immunoconjugates for research into cancers expressing the Axl type.</p>
    Cor e Forma:Liquid

    Ref: TM-T9901A-225

  • PKI (5-24),amide
    Targetmol
    + Info

    PKI (5-24),amide

    CAS:
    <p>PKI (5-24),amide is a 20-residue peptide, a potent PKA inhibitor with a Ki of 2.3 nM, derived from a cAMP inhibitor protein.</p>
    Fórmula:C94H149N33O30
    Cor e Forma:Solid
    Peso molecular:2221.4

    Ref: TM-T76482

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    EGFR/VEGFR2-IN-5

    <p>EGFR/VEGFR2-IN-5 (Compound 14) is an orally active dual inhibitor of EGFR and VEGFR2, exhibiting an IC50 value of 1.15 µM for VEGFR2 and 0.28 µM for EGFRT790M. This compound demonstrates significant anticancer activity.</p>
    Fórmula:C17H15N7O5S
    Cor e Forma:Solid
    Peso molecular:429.41

    Ref: TM-T205483

  • PROTAC EGFR degrader 11
    Targetmol
    + Info

    PROTAC EGFR degrader 11

    CAS:
    <p>PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR), with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 36 nM. This compound effectively degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild-type and EGFR mutant cells, exhibiting an IC50 of less than 100 nM.</p>
    Fórmula:C49H64ClFN10O7S
    Cor e Forma:Solid
    Peso molecular:991.61

    Ref: TM-T88077

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Cetuximab MMAE

    <p>Cetuximab-MMAE, an antibody-drug conjugate (ADC), combines an EGFR-targeting antibody with Monomethyl auristatin E (MMAE) to investigate colorectal and head and neck cancers.</p>
    Cor e Forma:Liquid
    Peso molecular:150 kDa

    Ref: TM-T9901A-219

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Inetetamab

    <p>Inetetamab is a recombinant humanized antibody targeting HER2 receptor domain IV, with anticancer activity, inducing pyroptosis in lung adenocarcinoma.</p>
    Pureza:96.54% (SEC-HPLC) - 96.54% (SEC-HPLC)
    Cor e Forma:Odour Liquid

    Ref: TM-T78335

  • PROTAC EGFR degrader 3
    Targetmol
    + Info

    PROTAC EGFR degrader 3

    CAS:
    <p>Potent PROTAC EGFR degrader 3; excellent against H1975/HCC827 cells; lysosome-involved mutant degradation.</p>
    Fórmula:C60H77N13O5S
    Cor e Forma:Solid
    Peso molecular:1092.4

    Ref: TM-T74351

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Antiproliferative agent-57

    <p>Antiproliferative agent-57 (compound M2) is a tumor angiogenesis inhibitor that suppresses VEGF secretion in SiHa cells under hypoxic conditions without inducing cytotoxicity (IC50=0.68 μM). It modulates the PI3K/AKT/mTOR and MAPK signaling pathways in tumor cells, thereby inhibiting the expression of HIF-1α and VEGF within tumor tissues.</p>
    Cor e Forma:Odour Solid

    Ref: TM-T200522

  • ErbB-2-binding peptide
    Targetmol
    + Info

    ErbB-2-binding peptide

    CAS:
    <p>ErbB-2-binding peptide (HER2-binding peptide), a tumor-targeting peptide, holds potential for cancer research applications [1].</p>
    Fórmula:C43H60N8O11
    Cor e Forma:Solid
    Peso molecular:864.98

    Ref: TM-T76542