CymitQuimica logo
Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

Exibir 13 mais subcategorias

Foram encontrados 1342 produtos de "Tirosina Quinase/Adaptador"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • CH6953755
    Targetmol
    + Info

    CH6953755

    CAS:
    CH6953755: oral YES1 kinase inhibitor, IC50 1.8 nM, potent, selective, anticancer, halts cell proliferation.
    Fórmula:C26H22F2N6O4S
    Pureza:98.87%
    Cor e Forma:Solid
    Peso molecular:552.55

    Ref: TM-T10784

  • MK-2461
    Targetmol
    + Info

    MK-2461

    CAS:
    MK-2461 is a novel inhibitor that targets multiple proteins and competitively binds to ATP sites, specifically inhibiting the activated c-Met protein with an
    Fórmula:C24H25N5O5S
    Pureza:95.41% - 99.67%
    Cor e Forma:Solid
    Peso molecular:495.55

    Ref: TM-T6094

  • Ropsacitinib
    Targetmol
    + Info

    Ropsacitinib

    CAS:
    <p>Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).</p>
    Fórmula:C20H17N9
    Pureza:99.87%
    Cor e Forma:Solid
    Peso molecular:383.41

    Ref: TM-T13237L

  • FIIN-1
    Targetmol
    + Info

    FIIN-1

    CAS:
    <p>FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3,</p>
    Fórmula:C32H39Cl2N7O4
    Pureza:98.75%
    Cor e Forma:Solid
    Peso molecular:656.6

    Ref: TM-T37426

  • TAK-020
    Targetmol
    + Info

    TAK-020

    CAS:
    <p>TAK-020 is a potent covalent inhibitor of Btk with potential antitumor activity for the study of rheumatoid arthritis and immune-related diseases.</p>
    Fórmula:C18H17N5O3
    Pureza:98.79%
    Cor e Forma:Solid
    Peso molecular:351.36

    Ref: TM-T9529

  • EGFR/ErbB-2 inhibitor-1
    Targetmol
    + Info

    EGFR/ErbB-2 inhibitor-1

    CAS:
    <p>EGFR/ErbB-2 inhibitor-1 is a selective ErbB2/HER2 inhibitor that effectively blocks ErbB2 and HER2 signaling.</p>
    Fórmula:C23H15ClFN3OS2
    Pureza:98.93%
    Cor e Forma:Solid
    Peso molecular:467.97

    Ref: TM-T79861

  • Zidesamtinib
    Targetmol
    + Info

    Zidesamtinib

    CAS:
    <p>Zidesamtinib (NVL-520) is a ROS1 fusion and resistance mutation inhibitor that inhibits ROS1 and can be used to study non-small cell lung cancer.</p>
    Fórmula:C22H22FN7O
    Pureza:99.74%
    Cor e Forma:Solid
    Peso molecular:419.455

    Ref: TM-T72953

  • Sevabertinib
    Targetmol
    + Info

    Sevabertinib

    CAS:
    <p>Sevabertinib (BAY 2927088) is an EGFR tyrosine kinase inhibitor, with anticancer activity, used in research on non-small cell lung cancer.</p>
    Fórmula:C24H25ClN4O5
    Pureza:99.81%
    Cor e Forma:Solid
    Peso molecular:484.93

    Ref: TM-T200964

  • Tyrphostin AG 538
    Targetmol
    + Info

    Tyrphostin AG 538

    CAS:
    <p>Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.</p>
    Fórmula:C16H11NO5
    Pureza:98.75%
    Cor e Forma:Soild
    Peso molecular:297.26

    Ref: TM-T67707

  • EGFR-IN-1 hydrochloride
    Targetmol
    + Info

    EGFR-IN-1 hydrochloride

    CAS:
    <p>EGFR-IN-1 HCl targets L858R/T790M EGFR mutants over wild-type; IC50: 4 nM in H1975, 28 nM in mutant HCC827 cells.</p>
    Fórmula:C28H31ClN6O4
    Pureza:99.16%
    Cor e Forma:Solid
    Peso molecular:551.04

    Ref: TM-T11157L

  • BGB-8035
    Targetmol
    + Info

    BGB-8035

    CAS:
    <p>BGB-8035 is a BTK inhibitor with antitumor activity that inhibits BTK, TEC, and EGFR.BGB-8035 is used in the study of tumors and autoimmune diseases.</p>
    Fórmula:C24H31N5O4
    Pureza:96.74%
    Cor e Forma:Solid
    Peso molecular:453.53

    Ref: TM-T73381

  • ALK-IN-27
    Targetmol
    + Info

    ALK-IN-27

    CAS:
    <p>Neladalkib (NVL-655) is an ALK inhibitor with antitumor activity for the study of non-small cell cancers.</p>
    Fórmula:C23H22ClFN6O
    Pureza:99.71%
    Cor e Forma:Solid
    Peso molecular:452.91

    Ref: TM-T83146

  • BTK inhibitor 1
    Targetmol
    + Info

    BTK inhibitor 1

    CAS:
    <p>BTK inhibitor 1 (Compound 27) is a BTK inhibitor (IC50: 0.11 nM) with an inhibitory effect on B-cell activation in hWB with an IC50 of 2 nM.</p>
    Fórmula:C24H23FN8O2
    Pureza:98.24% - 98.91%
    Cor e Forma:Solid
    Peso molecular:474.49

    Ref: TM-T35330

  • WAY-600
    Targetmol
    + Info

    WAY-600

    CAS:
    <p>WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).</p>
    Fórmula:C28H30N8O
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:494.59

    Ref: TM-T6730

  • AZ-23
    Targetmol
    + Info

    AZ-23

    CAS:
    <p>AZ-23 is an inhibitor of ATP-competitive and Trk kinase A/B/C.</p>
    Fórmula:C17H19ClFN7O
    Pureza:99.4%
    Cor e Forma:Solid
    Peso molecular:391.83

    Ref: TM-T14363

  • EGFR-IN-8
    Targetmol
    + Info

    EGFR-IN-8

    CAS:
    <p>EGFR-IN-8, a dual inhibitor targeting both EGFR and c-Met, shows potential as a promising candidate for further development in treating EGFR TKI-resistant NSCLC</p>
    Fórmula:C32H23ClF3N7O4
    Pureza:99.51%
    Cor e Forma:Solid
    Peso molecular:662.02

    Ref: TM-T11162

  • Src Inhibitor 3
    Targetmol
    + Info

    Src Inhibitor 3

    CAS:
    Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.
    Fórmula:C34H32ClFN8O4
    Pureza:98.35%
    Cor e Forma:Solid
    Peso molecular:671.12

    Ref: TM-T13000

  • ONO-7579
    Targetmol
    + Info

    ONO-7579

    CAS:
    <p>ONO-7579, an orally active TRKA inhibitor, effectively suppresses tumor growth by inhibiting TRKA phosphorylation. In KM12 colorectal cancer cells, it exhibits an EC 50 of 17.6 ng/g, indicating that a concentration of 17.6 ng per gram of tumor tissue reduces the activity of phosphorylated TRKA by 50%. This compound is utilized in cancer research.</p>
    Fórmula:C24H18ClF3N6O4S
    Cor e Forma:Solid
    Peso molecular:578.95

    Ref: TM-T200301

  • FMP-API-1
    Targetmol
    + Info

    FMP-API-1

    CAS:
    <p>FMP-API-1 is an inhibitor of the A-kinase anchoring protein (AKAP)-PKA interaction. It binds to the allosteric site of the PKAR subunit, enhancing the activity of PKA and AQP2 in PKA knockout cell lines of the renal cortex collecting duct (mpkCCD cells). FMP-API-1 holds potential for studying nephrogenic diabetes insipidus (NDI).</p>
    Fórmula:C13H14N2O2
    Cor e Forma:Solid
    Peso molecular:230.262

    Ref: TM-T204439

  • MerTK/Axl-IN-1
    Targetmol
    + Info

    MerTK/Axl-IN-1

    CAS:
    <p>MerTK/Axl-IN-1 (Compound A-910) is a potent and selective dual inhibitor of MerTK/Axl, exhibiting IC50 values of 4.2 nM and 8.8 nM in Ba/F3 cells, and 0.2 nM and 0.9 nM in HTRF cells, respectively. It effectively inhibits pMerTK in vivo and possesses a long half-life and high oral bioavailability.</p>
    Fórmula:C40H47FN6O4
    Cor e Forma:Solid
    Peso molecular:694.84

    Ref: TM-T200517