CymitQuimica logo
Tirosina Quinase/Adaptador

Tirosina Quinase/Adaptador

Os inibidores de tirosina quinase e adaptadores são compostos que têm como alvo as tirosina quinases e suas proteínas adaptadoras associadas, que desempenham papéis fundamentais na sinalização celular, crescimento e diferenciação. Esses inibidores são ferramentas essenciais na pesquisa sobre o câncer, pois muitas tirosina quinases estão envolvidas nas vias de sinalização que impulsionam o crescimento e a metástase dos tumores. Ao inibir as tirosina quinases, esses compostos podem bloquear cascatas de sinalização críticas, oferecendo potenciais estratégias terapêuticas para vários tipos de câncer e outras doenças que envolvem sinalização celular anormal. Na CymitQuimica, oferecemos uma ampla gama de inibidores de tirosina quinase e adaptadores de alta qualidade para apoiar sua pesquisa em oncologia, biologia molecular e desenvolvimento de terapias direcionadas.

Subcategorias de "Tirosina Quinase/Adaptador"

Exibir 13 mais subcategorias

Foram encontrados 1372 produtos de "Tirosina Quinase/Adaptador"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • CSF1R-IN-2
    Targetmol
    + Info

    CSF1R-IN-2

    CAS:
    <p>CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).</p>
    Fórmula:C20H20FN7O2
    Pureza:99.29%
    Cor e Forma:Solid
    Peso molecular:409.42

    Ref: TM-T13194

  • Lanraplenib
    Targetmol
    + Info

    Lanraplenib

    CAS:
    <p>Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.</p>
    Fórmula:C23H25N9O
    Pureza:98.35%
    Cor e Forma:Solid
    Peso molecular:443.5

    Ref: TM-T11824LL

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Robatumumab

    CAS:
    <p>Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.</p>
    Pureza:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)
    Cor e Forma:Liquid

    Ref: TM-T76759

  • Onartuzumab
    Targetmol
    + Info

    Onartuzumab

    CAS:
    <p>Onartuzumab (MetMAb) is a humanized monoclonal antibody targeting c-MET, with antitumor effects by blocking HGF and signal transduction.</p>
    Pureza:97.3%
    Cor e Forma:Liquid
    Peso molecular:146.99 kDa

    Ref: TM-T76780

  • Delgocitinib
    Targetmol
    + Info

    Delgocitinib

    CAS:
    <p>Delgocitinib is a potent JAK inhibitor (IC50: 2.8-58 nM), treats inflammatory diseases, and is the first topical drug for atopic dermatitis.</p>
    Fórmula:C16H18N6O
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:310.35

    Ref: TM-T15096

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Duligotuzumab

    CAS:
    <p>Duligotuzumab is a dual-targeting anti-EGFR/HER3 mAb that blocks signaling and induces ADCC for tumors with poor prognosis.</p>
    Pureza:95% - 95%
    Cor e Forma:Liquid

    Ref: TM-T9901A-828

  • MS9427
    Targetmol
    + Info

    MS9427

    CAS:
    <p>MS9427: PROTAC EGFR degrader, 7.1 nM (WT), 4.3 nM (L858R); targets mutant via UPS and autophagy; inhibits NSCLC cell growth; anticancer research.</p>
    Fórmula:C48H58ClFN8O12
    Cor e Forma:Solid
    Peso molecular:993.47

    Ref: TM-T74633

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    DSPE-PEG2000-GE11

    <p>DSPE-PEG2000-GE11 is a PEG compound composed of DSPE and an EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells that overexpress EGFR. DSPE-PEG2000-GE11 is utilized in drug delivery.</p>
    Cor e Forma:Odour Solid

    Ref: TM-TCL-01177

  • Compound TPX-0046
    Targetmol
    + Info

    Compound TPX-0046

    CAS:
    <p>Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.</p>
    Fórmula:C21H21FN6O3
    Pureza:99.94%
    Cor e Forma:Soild
    Peso molecular:424.43

    Ref: TM-T67779

  • CREBtide
    Targetmol
    + Info

    CREBtide

    CAS:
    <p>CREBtide is a synthetic substrate for PKA (Km=3.9 µM), which is based on the phosphorylation sequence in d-CREB (cAMP response element binding protein).</p>
    Fórmula:C73H129N29O19
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1716.99

    Ref: TM-TP1876

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Cixutumumab

    CAS:
    <p>Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor activation, impeding</p>
    Pureza:98.5% (SDS-PAGE); 97.5% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.5% (SEC-HPLC)
    Cor e Forma:Liquid

    Ref: TM-T78279

  • HER2/neu (654-662) GP2
    Targetmol
    + Info

    HER2/neu (654-662) GP2

    CAS:
    <p>Phage display selected Affibody ligands for HER2/neu from a protein library based on a 58-residue Staphylococcal protein A Z domain.</p>
    Fórmula:C42H77N9O11
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:884.11

    Ref: TM-TP1583

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    JBJ-09-063 TFA

    <p>JBJ-09-063 TFA, an EGFR inhibitor selective for EGFR mutations, IC50s: 0.147-0.396 nM, blocks EGFR/Akt/ERK signaling, for EGFR-mutant lung cancer research.</p>
    Fórmula:C33H30F4N4O5S
    Cor e Forma:Solid
    Peso molecular:670.67

    Ref: TM-T74561

  • KYL peptide
    Targetmol
    + Info

    KYL peptide

    CAS:
    <p>EphA4 inhibitor, Kd 0.8 μM, blocks EphA4-EphrinA5; avoids AβO damage, preserves spines &amp; LTP; long half-life (8-12h), neuroprotective.</p>
    Fórmula:C74H108N14O17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1465.75

    Ref: TM-TP1895

  • EGFR-IN-76
    Targetmol
    + Info

    EGFR-IN-76

    CAS:
    <p>EGFR-IN-76 is a potent EGFR inhibitor.</p>
    Fórmula:C30H30ClFN6O2
    Pureza:97.02% - 97.72%
    Cor e Forma:Solid
    Peso molecular:561.05

    Ref: TM-T75120

  • HER2-IN-14
    Targetmol
    + Info

    HER2-IN-14

    CAS:
    <p>HER2-IN-14 (Compound 34) is a potent inhibitor of HER2, achieving an inhibitory concentration (IC50) of 18 nM.</p>
    Fórmula:C26H23ClF2N8O3
    Cor e Forma:Solid
    Peso molecular:568.96

    Ref: TM-T75165

  • Nuzefatide
    Targetmol
    + Info

    Nuzefatide

    CAS:
    <p>Nuzefatide is a peptide that binds to liver protein receptors.</p>
    Fórmula:C105H162N32O27S3
    Cor e Forma:Solid
    Peso molecular:2400.80

    Ref: TM-TP3269

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Valanafusp alfa

    CAS:
    <p>Valanafusp alfa (AGT-181) is a fusion protein targeting HIR and IDUA for MPS I research.</p>
    Cor e Forma:Liquid

    Ref: TM-T76964

  • BMS-599626 2HCL(714971-09-2 Free base)
    Targetmol
    + Info

    BMS-599626 2HCL(714971-09-2 Free base)

    CAS:
    <p>BMS-599626 2HCL (AC480 2HCl) is a BMS-599626 derivative.</p>
    Fórmula:C27H29Cl2FN8O3
    Pureza:99.11%
    Cor e Forma:Odour Solid
    Peso molecular:603.47

    Ref: TM-T2610L

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    PROTAC EGFR degrader 2

    <p>Potent PROTAC EGFR degrader 2; IC50: 4.0 nM, DC50: 36.51 nM; inhibits cell growth; for NTR-responsive synthesis.</p>
    Fórmula:C58H72ClFN12O8S
    Cor e Forma:Solid
    Peso molecular:1151.78

    Ref: TM-T74333