Thrombin
Thrombin inhibitors are compounds that block thrombin, an enzyme involved in the blood coagulation process that also has a role in promoting angiogenesis. Thrombin can stimulate the formation of new blood vessels in tumors, aiding in their growth and metastasis. By inhibiting thrombin, these compounds can reduce angiogenesis and tumor progression. Thrombin inhibitors are important in both cancer research and the study of vascular diseases. At CymitQuimica, we provide a selection of high-quality thrombin inhibitors to support your research in hemostasis, oncology, and angiogenesis.
Found 56 products of "Thrombin"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Dabigatran etexilate
CAS:Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Formula:C34H41N7O5Purity:98.19% - 99.98%Color and Shape:White PowderMolecular weight:627.73Dabigatran ethyl ester hydrochloride
CAS:Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Formula:C27H30ClN7O3Purity:99.65%Color and Shape:SolidMolecular weight:536.03Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)
CAS:Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide with greater thrombin affinity than Hirugen, exhibiting a dissociation constant (KFormula:C64H88N10O26SPurity:98%Color and Shape:SolidMolecular weight:1445.5Acetyl-Hirudin (54-65) (sulfated)
CAS:Acetyl-Hirudin (54-65) (sulfated) binds thrombin-rHCII(L444R), blocking rHCII's N-terminal/thrombin exosite I interaction, stabilizing the complex.Formula:C68H95N13O29SColor and Shape:SolidMolecular weight:1590.63Thrombin inhibitor 13
Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.Formula:C16H17ClN6OSColor and Shape:SolidMolecular weight:376.864Hirullin P18
CAS:Hirullin P18 is a potent thrombin inhibitor with anticoagulant properties [1].Formula:C68H96N14O29Purity:98%Color and Shape:SolidMolecular weight:1573.57Thrombin (MW 37kDa)
CAS:Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.Purity:98%Color and Shape:SolidMolecular weight:37kDaH-Gly-Arg-pNA dihydrochloride
CAS:H-Gly-Arg-pNA 2HCl, a peptide, binds 1,2 thrombin; colorimetric quantification at 405 nm indicates thrombin activity.Formula:C14H23Cl2N7O4Purity:99.14%Color and Shape:SolidMolecular weight:424.28Hirudin (54-65) (TFA)
Hirudin (54-65) TFA, a segment of the 65-amino-acid protein Hirudin, exhibits anticoagulant properties [1].Color and Shape:Odour SolidKnob A peptide GPRPFPAC
CAS:Knob A peptide GPRPFPAC is a fibrin knob peptide. The PEGylated form of Knob A peptide GPRPFPAC exhibits enhanced anticoagulant activity.Formula:C38H57N11O9SColor and Shape:SolidMolecular weight:843.99Fibrinopeptide B, human
CAS:Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.Formula:C66H93N19O25Purity:98%Color and Shape:SolidMolecular weight:1552.56PM 102
CAS:Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).Formula:C235H425N111O64Purity:98%Color and Shape:SolidMolecular weight:5830Thrombin receptor peptide ligand
CAS:Thrombin receptor peptide ligand, a thrombin receptor antagonist, serves as an antithrombotic agent [1].Formula:C33H54N10O8Purity:98%Color and Shape:SolidMolecular weight:718.84TFLLRNPNDK-NH2
CAS:TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP).Formula:C54H89N17O15Purity:98%Color and Shape:SolidMolecular weight:1216.39Ichorcumab
CAS:Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Color and Shape:LiquidSulodexide
CAS:Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Color and Shape:SolidPlatelet aggregation-IN-1
Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.Formula:C18H13N3O4Molecular weight:335.09061Fibrinogen-Binding Peptide
CAS:Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.Formula:C25H39N7O8Purity:98%Color and Shape:SolidMolecular weight:565.62Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Color and Shape:Odour SolidRef: TM-L1100
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireHirudin (55-65) (sulfated)
CAS:Hirudin (55-65) (sulfated), a fragment of Hirudin, is a thrombin inhibitor with anticoagulant effects and blood anticoagulant properties.Formula:C64H90N12O27SColor and Shape:SolidMolecular weight:1491.53
