Thrombin
Thrombin inhibitors are compounds that block thrombin, an enzyme involved in the blood coagulation process that also has a role in promoting angiogenesis. Thrombin can stimulate the formation of new blood vessels in tumors, aiding in their growth and metastasis. By inhibiting thrombin, these compounds can reduce angiogenesis and tumor progression. Thrombin inhibitors are important in both cancer research and the study of vascular diseases. At CymitQuimica, we provide a selection of high-quality thrombin inhibitors to support your research in hemostasis, oncology, and angiogenesis.
Found 56 products of "Thrombin"
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Dabigatran etexilate
CAS:Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.Formula:C34H41N7O5Purity:98.19% - 99.98%Color and Shape:White PowderMolecular weight:627.73Dabigatran ethyl ester hydrochloride
CAS:Dabigatran prevents blood clots, inhibiting NQO2 and thrombin with IC50 0.8 μM.Formula:C27H30ClN7O3Purity:99.65%Color and Shape:SolidMolecular weight:536.03Idarucizumab
CAS:Idarucizumab, a humanized monoclonal antibody fragment, serves as the first reversal agent for direct oral anticoagulants (DOACs).Color and Shape:LiquidSuccinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated)
CAS:Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide with greater thrombin affinity than Hirugen, exhibiting a dissociation constant (KFormula:C64H88N10O26SPurity:98%Color and Shape:SolidMolecular weight:1445.5Hirullin P18
CAS:Hirullin P18 is a potent thrombin inhibitor with anticoagulant properties [1].Formula:C68H96N14O29Purity:98%Color and Shape:SolidMolecular weight:1573.57TFLLRNPNDK-NH2
CAS:TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP).Formula:C54H89N17O15Purity:98%Color and Shape:SolidMolecular weight:1216.39Thrombin receptor peptide ligand
CAS:Thrombin receptor peptide ligand, a thrombin receptor antagonist, serves as an antithrombotic agent [1].Formula:C33H54N10O8Purity:98%Color and Shape:SolidMolecular weight:718.84Thrombin inhibitor 13
Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.Formula:C16H17ClN6OSColor and Shape:SolidMolecular weight:376.864Protease Inhibitor Library
A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;Color and Shape:Odour SolidRef: TM-L1100
1mgTo inquire30μL*10mM (DMSO)To inquire50μL*10mM (DMSO)To inquire100μL*10mM (DMSO)To inquire250μL*10mM (DMSO)To inquireHirudin (55-65) (sulfated)
CAS:Hirudin (55-65) (sulfated), a fragment of Hirudin, is a thrombin inhibitor with anticoagulant effects and blood anticoagulant properties.Formula:C64H90N12O27SColor and Shape:SolidMolecular weight:1491.53Acetyl-Hirudin (54-65) (sulfated)
CAS:Acetyl-Hirudin (54-65) (sulfated) binds thrombin-rHCII(L444R), blocking rHCII's N-terminal/thrombin exosite I interaction, stabilizing the complex.Formula:C68H95N13O29SColor and Shape:SolidMolecular weight:1590.63Knob A peptide GPRPFPAC
CAS:Knob A peptide GPRPFPAC is a fibrin knob peptide. The PEGylated form of Knob A peptide GPRPFPAC exhibits enhanced anticoagulant activity.Formula:C38H57N11O9SColor and Shape:SolidMolecular weight:843.99Metolazone
CAS:Metolazone (SR-720-22) is a quinazoline-sulfonamide derived diuretic that inhibits sodium chloride symporters.
Formula:C16H16ClN3O3SPurity:98.14% - 98.5%Color and Shape:Crystals From Ethanol SolidMolecular weight:365.83H-Gly-Arg-pNA dihydrochloride
CAS:H-Gly-Arg-pNA 2HCl, a peptide, binds 1,2 thrombin; colorimetric quantification at 405 nm indicates thrombin activity.Formula:C14H23Cl2N7O4Purity:99.14%Color and Shape:SolidMolecular weight:424.28Ichorcumab
CAS:Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Color and Shape:LiquidHirudin (54-65) (TFA)
Hirudin (54-65) TFA, a segment of the 65-amino-acid protein Hirudin, exhibits anticoagulant properties [1].Color and Shape:Odour SolidFibrinogen-Binding Peptide
CAS:Fibrinogen-binding peptide mimics vitronectin site and activates platelets; thrombin turns it to fibrin.Formula:C25H39N7O8Purity:98%Color and Shape:SolidMolecular weight:565.62Thrombin (MW 37kDa)
CAS:Thrombin (MW 37kDa) is a trypsin-like allosteric serine protease.Purity:98%Color and Shape:SolidMolecular weight:37kDaSulodexide
CAS:Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Color and Shape:SolidFibrinopeptide B, human
CAS:Fibrinopeptide B (FPB) is produced during the cleavage of fibrinogen, by thrombin, to fibrin monomer.Formula:C66H93N19O25Purity:98%Color and Shape:SolidMolecular weight:1552.56PM 102
CAS:Peptide that reverses the anticoagulant effect of heparin. Potently binds heparin (Kd = 36 nM in vitro).Formula:C235H425N111O64Purity:98%Color and Shape:SolidMolecular weight:5830Platelet aggregation-IN-1
Platelet aggregation-IN-1 (Compound 10e) acts as an inhibitor of platelet aggregation and can achieve complete (100%) inhibition of thrombin-induced platelet aggregation at a concentration of 50 μM.Formula:C18H13N3O4Molecular weight:335.09061Anti-Coagulation Factor II Antibody (8M286)
Anti-Coagulation Factor II Antibody (8M286) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (8M286) can be used in ELISA.Color and Shape:Odour LiquidAnti-Coagulation Factor II Antibody (2P591)
Anti-Coagulation Factor II Antibody (2P591) is a Rabbit antibody targeting Coagulation Factor II. Anti-Coagulation Factor II Antibody (2P591) can be used in WB.Color and Shape:Odour LiquidDabigatran ethyl ester
CAS:Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.Formula:C27H29N7O3Purity:99.98%Color and Shape:SolidMolecular weight:499.56Coagulation Factor II Protein, Mouse, Recombinant (His)
Coagulation Factor II Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:69.3 kDa (predicted); 85 kDa (reducing conditions)Coagulation Factor II Protein, Rat, Recombinant (His)
Coagulation Factor II Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Color and Shape:Lyophilized PowderMolecular weight:69.5 kDa (predicted)Argatroban Monohydrate
CAS:Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.Formula:C23H38N6O6SPurity:99.51%Color and Shape:SolidMolecular weight:526.65Edoxaban Tosylate Monohydrate
CAS:Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.Formula:C31H40ClN7O8S2Purity:99.86% - 99.91%Color and Shape:SolidMolecular weight:738.27Cycloolivil
CAS:Cycloolivil (Isoolivil) is a natural polyphenolic compound with a significant radical scavenging activity present in olive trees.Formula:C20H24O7Purity:98%Color and Shape:SolidMolecular weight:376.4Avatrombopag
CAS:Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiationFormula:C29H34Cl2N6O3S2Purity:99.01% - 99.63%Color and Shape:SolidMolecular weight:649.65Ref: TM-T7417
1mg57.00€5mg120.00€10mg187.00€25mg339.00€50mg540.00€100mg747.00€200mg1,035.00€1mL*10mM (DMSO)167.00€NQ301
CAS:NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).Formula:C18H12ClNO3Purity:99.74% - 99.76%Color and Shape:SolidMolecular weight:325.75Ximelagatran
CAS:Ximelagatran, oral direct thrombin inhibitor, transforms to active melagatran in body.Formula:C24H35N5O5Purity:95.48% - 99.60%Color and Shape:SolidMolecular weight:473.57MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formula:C9H7NO4Purity:98.53%Color and Shape:Yellow PowderMolecular weight:193.16Lusutrombopag
CAS:Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients withFormula:C29H32Cl2N2O5SPurity:99.96%Color and Shape:SolidMolecular weight:591.55Ref: TM-TQ0223
1mg60.00€2mg87.00€5mg130.00€10mg197.00€25mg394.00€50mg595.00€100mg888.00€200mg1,224.00€1mL*10mM (DMSO)167.00€TRAP-6
CAS:TRAP-6 (Thrombin Receptor Activator Peptide 6)(2TFA) is an agonist of protease-activated receptor 1 (PAR1).Formula:C34H56N10O9Purity:>99.99%Color and Shape:SolidMolecular weight:748.87Ref: TM-T7625
1mg40.00€2mg52.00€5mg88.00€10mg126.00€25mg274.00€50mg411.00€100mg550.00€200mg785.00€1mL*10mM (DMSO)126.00€Dabigatran
CAS:Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.Formula:C25H25N7O3Purity:97.44% - 98.7%Color and Shape:Tan SolidMolecular weight:471.51Enoxaparin sodium
CAS:Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.Formula:C42H59N3Na4O35S2Purity:98%Color and Shape:SolidMolecular weight:1322AEBSF hydrochloride
CAS:AEBSF hydrochloride (Pefabloc SC) is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, thrombin, plasmin, and trypsin.Formula:C8H11ClFNO2SPurity:98% - 99.81%Color and Shape:White PowderMolecular weight:239.69H-D-Phe-Pip-Arg-pNA dihydrochloride
CAS:H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238) is a sensitive and accurate thrombin detection substrate for measuring antithrombin-heparin cofactor (AT-III).
Formula:C27H38Cl2N8O5Purity:99.47%Color and Shape:SolidMolecular weight:625.55Bivalirudin
CAS:Bivalirudin (BG-8967) is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clottingFormula:C98H138N24O33Purity:98.8% - >99.99%Color and Shape:White To Off-White PowderMolecular weight:2180.29Dabigatran Etexilate Mesylate
CAS:Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor.Formula:C34H41N7O5·CH4O3SPurity:99.91%Color and Shape:SolidMolecular weight:723.84Ref: TM-T5133
5mg39.00€10mg54.00€25mg71.00€50mg90.00€100mg105.00€200mg160.00€500mg227.00€1mL*10mM (DMSO)60.00€Argatroban
CAS:Argatroban (MCI-9038), a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.Formula:C23H36N6O5SPurity:99.77% - >99.99%Color and Shape:White To Off-White Crystalline SolidMolecular weight:508.63Ref: TM-T0155
5mg37.00€10mg56.00€25mg98.00€50mg152.00€100mg222.00€200mg331.00€500mg537.00€1mL*10mM (DMSO)43.00€TPO agonist 1
CAS:TPO agonist 1, Thrombopoietin (TPO) mimetic, promotes platelet/megakaryocyte production, for thrombocytopenia research.Formula:C25H22N8O2Purity:98%Color and Shape:SolidMolecular weight:466.49Efegatran sulfate
CAS:Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.Formula:C21H34N6O7SPurity:≥98% - ≥98%Color and Shape:SolidMolecular weight:514.6Flovagatran
CAS:Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.Formula:C27H36BN3O7Purity:99.56%Color and Shape:SolidMolecular weight:525.4Atopaxar Hydrobromide
CAS:Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H39BrFN3O5Purity:98%Color and Shape:SolidMolecular weight:608.54Atopaxar
CAS:Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H38FN3O5Purity:97.07% - 98.07%Color and Shape:SolidMolecular weight:527.63OM-189
CAS:OM-189 is a selective inhibitor of synthetic thrombin.Formula:C24H36N6O3SPurity:98%Color and Shape:SolidMolecular weight:488.65Melagatran
CAS:Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.Formula:C22H31N5O4Purity:98.29% - >99.99%Color and Shape:SolidMolecular weight:429.51Ref: TM-T11994
1mg487.00€5mg1,134.00€10mg1,468.00€25mg2,215.00€50mg2,962.00€100mg4,024.00€1mL*10mM (DMSO)1,071.00€Thrombin inhibitor 1
CAS:Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).Formula:C22H20Cl2F2N4O3Purity:98%Color and Shape:SolidMolecular weight:497.32SCH79797 dihydrochloride
CAS:SCH79797 dihydrochloride is a PAR1 antagonist with IC50 70 nM, Ki 35 nM, antiproliferative, and pro-apoptotic properties.Formula:C23H27Cl2N5Purity:99.5%Color and Shape:SolidMolecular weight:444.4SAR107375
CAS:SAR107375 is a potent, orally active dual inhibitor of thrombin and factor Xa, with K_i values of 1 nM and 8 nM for factor Xa and thrombin, respectively [1].Formula:C24H30ClN5O5S2Color and Shape:SolidMolecular weight:568.11NAPAP
CAS:NAPAP is a thrombin inhibitor with potent anticoagulant activity (Ki: 2.1 nM). It selectively inhibits thrombin through a rapid binding mechanism while exhibiting weaker inhibition of trypsin, Factor Xa, and plasmin. NAPAP can be utilized for research into thrombotic conditions, including venous thrombosis and myocardial infarction.Formula:C27H31N5O4SColor and Shape:SolidMolecular weight:521.63Odiparcil
CAS:Odiparcil is an orally active beta-d-thioxyloside analog.Formula:C15H16O6SPurity:98%Color and Shape:SolidMolecular weight:324.35Antiplatelet agent 3
CAS:Antiplatelet agent 3 (Compound K-10) is a compound with antiplatelet aggregation activity, exhibiting IC50 values of 2.55, 3.22, and 2.09 mg/mL for platelet aggregation induced by ADP, AA, and COL, respectively. It holds potential for research in cardiovascular diseases.Formula:C38H32N2O5Color and Shape:SolidMolecular weight:596.671
