CymitQuimica logo
Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

Show 6 more subcategories

Found 6170 products of "Apoptosis"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • MS1943

    CAS:
    MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).
    Formula:C42H54N8O3
    Purity:95.41% - 95.82%
    Color and Shape:Solid
    Molecular weight:718.93

    Ref: TM-T13780

    1mg
    39.00€
    2mg
    52.00€
    5mg
    84.00€
    10mg
    130.00€
    25mg
    250.00€
    50mg
    439.00€
    100mg
    802.00€
    200mg
    1,324.00€
    1mL*10mM (DMSO)
    120.00€
  • Ganoderic acid T1


    Ganoderic acid T1, a derivative of Ganoderic acid T, triggers cancer cell apoptosis by boosting ROS and activating caspases.
    Formula:C34H50O7
    Color and Shape:Solid
    Molecular weight:570.76

    Ref: TM-T75632

    5mg
    To inquire
    50mg
    To inquire
  • Camrelizumab

    CAS:

    Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up

    Purity:95% - 98.6%
    Color and Shape:Liquid
    Molecular weight:143.7 kDa

    Ref: TM-T37535

    1mg
    160.00€
    5mg
    547.00€
    10mg
    782.00€
    25mg
    1,159.00€
  • SPOP-IN-6lc

    CAS:

    SPOP-IN-6lc is a SPOP inhibitor with oncogenic effects in renal cancer cells.SPOP-IN-6lc can be used to study apoptosis.

    Formula:C26H31N7O2S
    Purity:99.19%
    Color and Shape:Solid
    Molecular weight:505.64

    Ref: TM-T69877

    1mg
    115.00€
    5mg
    274.00€
    10mg
    411.00€
    25mg
    825.00€
    50mg
    1,216.00€
    100mg
    1,673.00€
    200mg
    2,252.00€
  • Thalidomide-NH-amido-C6-NH2 hydrochloride


    Thalidomide-NH-amido-C6-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate that includes a thalidomide-based cereblon ligand and a linker, designed for the synthesis of PROTAC.
    Formula:C21H28ClN5O5
    Molecular weight:465.1779

    Ref: TM-T208135

    10mg
    To inquire
    50mg
    To inquire
  • (-)-Mcl-1 inhibitor 21

    CAS:

    (-)-Mcl-1 inhibitor 21 (Example 1-38) is an Mcl-1 inhibitor with an IC50 of 7.51 μM. It exhibits pro-apoptotic and anti-proliferative activity against SUDHL5 and SUDHL10 cell lines, making it useful for cancer research.

    Formula:C32H33N3O4
    Color and Shape:Solid
    Molecular weight:523.622

    Ref: TM-T204636

    10mg
    To inquire
    50mg
    To inquire
  • P-gp inhibitor 16


    P-gp inhibitor 16 (compound 14) is an inhibitor of p-glycoprotein. It significantly enhances apoptosis induced by doxorubicin and displays anticancer properties.
    Formula:C35H35N5O4
    Molecular weight:589.2689

    Ref: TM-T208251

    10mg
    To inquire
    50mg
    To inquire
  • Cu(I) chelator 1


    Cu(I) chelator 1 (Compound LH2) is a chelating agent specifically targeting the Cu(I) redox state. It inhibits the production of ROS.
    Formula:C16H27NO4S3
    Molecular weight:393.11022

    Ref: TM-T209189

    10mg
    To inquire
    50mg
    To inquire
  • PROTAC FLT3/CDK9 degrader-1


    Potent PROTAC degrader for FLT3/CDK9, induces apoptosis, and shows promise for FLT3-ITD mutated AML research.
    Formula:C48H62N12O7
    Color and Shape:Solid
    Molecular weight:919.08

    Ref: TM-T74707

    5mg
    To inquire
    50mg
    To inquire
  • EGFR-IN-107


    EGFR-IN-107 (compound 3r) is an orally active EGFR inhibitor with IC50 values of 0.4333 μM for EGFRWT and 0.0438 μM for EGFRL858R/T790M. It exhibits antiproliferative activity, effectively inhibiting the proliferation of H1975 cells and inducing apoptosis (apoptosis). EGFR-IN-107 is applicable in cancer research.
    Formula:C34H36FN7O2
    Molecular weight:593.29145

    Ref: TM-T209547

    10mg
    To inquire
    50mg
    To inquire
  • NCA029


    NCA029 is a potent activator of human caseinolytic protease P (HsClpP) with an EC50 of 0.15 μM. It targets HsClpPP and triggers an ATF3-dependent integrated stress response, resulting in the death of colon cancer cells.
    Formula:C22H20F3N3O
    Molecular weight:399.15585

    Ref: TM-T209245

    10mg
    To inquire
    50mg
    To inquire
  • 12-HETE

    CAS:
    12-HETE ((±)12-HETE) is a regulator of PGE2, having both antithrombotic and prothrombotic effects.
    Formula:C20H32O3
    Color and Shape:Solid
    Molecular weight:320.47

    Ref: TM-T35507

    25µg
    233.00€
    50µg
    442.00€
    100µg
    832.00€
    250µg
    1,783.00€
  • Canfosfamide

    CAS:
    Canfosfamide, a prodrug activated by GSTP1-1, induces apoptosis and inhibits DNA-PK, producing an alkylating agent for cancer research.
    Formula:C26H40Cl4N5O10PS
    Color and Shape:Solid
    Molecular weight:787.47

    Ref: TM-T75245

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • OICR12694 TFA

    CAS:
    OICR12694 (JNJ-65234637) TFA, an orally active B cell lymphoma 6 (BCL6) inhibitor [1], demonstrates effectiveness in targeting BCL6 pathways.
    Formula:C29H28ClF3N8O4·xC2HF3O2
    Color and Shape:Solid

    Ref: TM-T75105

    5mg
    To inquire
    50mg
    To inquire
  • NSC90616


    NSC90616 is a mutant p53 rescue compound [1] .
    Formula:C23H30FNa2O9P
    Color and Shape:Solid
    Molecular weight:546.43

    Ref: TM-T74324

    5mg
    To inquire
    50mg
    To inquire
  • sEH inhibitor-19


    sEH inhibitor-19 (Compound (R)-14i) is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.2 nM. This compound suppresses the expression of TNF-α and IL-6 and exhibits anti-inflammatory effects in mouse models of acute pancreatitis and Carrageenan-induced edema.
    Formula:C28H28F3N3O4
    Color and Shape:Solid
    Molecular weight:527.535

    Ref: TM-T204461

    10mg
    To inquire
    50mg
    To inquire
  • Anticancer agent 178


    Anticanceragent 178 (compound C2) is a potent anticancer compound. It effectively inhibits the proliferation and metabolic activity of MDA-MB 231 cells, with IC50 values of 1.1 and 4.2 μM, respectively. Additionally, Anticanceragent 178 induces ferroptosis and necroptosis in cells.
    Formula:C32H30ClFeN2O6
    Molecular weight:629.11418

    Ref: TM-T208865

    10mg
    To inquire
    50mg
    To inquire
  • Milademetan tosylate hydrate

    CAS:
    Milademetan tosylate hydrate, an oral MDM2 inhibitor targeting AML and solid tumors, induces G1 arrest and apoptosis.
    Formula:C37H44Cl2FN5O8S
    Color and Shape:Solid
    Molecular weight:808.74

    Ref: TM-T73634

    5mg
    To inquire
    50mg
    To inquire
  • Chloranthalactone B

    CAS:
    Chloranthalactone B, a sesquiterpenoid from Sarcandra glabra, inhibits inflammation via AP-1 & p38 MAPK.
    Formula:C15H16O3
    Color and Shape:Solid
    Molecular weight:244.29

    Ref: TM-T75561

    5mg
    To inquire
    50mg
    To inquire
  • Tubulin polymerization-IN-43

    CAS:
    Tubulin polymerization-IN-43 disrupts microtubules, arrests cell cycle, and induces apoptosis in leukemia by targeting colchicine sites.
    Formula:C17H13F4N3O
    Purity:99.98%
    Color and Shape:Soild
    Molecular weight:351.3

    Ref: TM-T77647

    1mg
    70.00€
    5mg
    136.00€
    10mg
    187.00€
    25mg
    309.00€
    50mg
    408.00€
    100mg
    560.00€
    200mg
    750.00€
  • RET-IN-4

    CAS:
    RET-IN-4: Oral RET inhibitor, IC50 ~1 nM for variants. Selective over JAK2/FLT3. Potent anticancer use.
    Formula:C27H31FN10O2
    Color and Shape:Solid
    Molecular weight:546.611

    Ref: TM-T40097

    5mg
    873.00€
  • PRDX1-IN-2


    PRDX1-IN-2 (compound 15) is a selective inhibitor of the antioxidant enzyme Peroxiredoxin 1 (PRDX1) with an IC50 of 0.35 μM. It reduces mitochondrial membrane potential in SW620 cells, potentially due to increased ROS resulting from PRDX1 inhibition, leading to apoptosis. PRDX1-IN-2 is applicable in colorectal cancer research.

    Ref: TM-T209850

    10mg
    To inquire
    50mg
    To inquire
  • DMUP

    CAS:
    DMUP inhibits CD47-SIRPα, induces apoptosis, boosts macrophage activity in A549 cells, and has antitumor properties.
    Formula:C24H24Cl2N2O10Pt
    Color and Shape:Solid
    Molecular weight:766.45

    Ref: TM-T73564

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Necrosis inhibitor 2 (hydrocholide)


    Necrosis inhibitor 2 hydrochloride (Compound B19) is an agent that inhibits cellular necrosis. It is useful for researching diseases associated with necrotic pathways, including inflammation, cancer, metabolic disorders, and neurodegenerative diseases.
    Formula:C24H26ClN5O5
    Molecular weight:499.16225

    Ref: TM-T208775

    10mg
    To inquire
    50mg
    To inquire
  • DA5-HTL


    DA5-HTL is a compound that combines dasatinib with the HaloTag system, effectively inhibiting the growth of tumor cells, with a GI50 of 1.923 nM.
    Formula:C39H58Cl2N8O8S
    Molecular weight:868.34754

    Ref: TM-T208773

    10mg
    To inquire
    50mg
    To inquire
  • Thalidomide-NH-C6-NH-Boc

    CAS:
    Thalidomide-based E3 ligase ligand for PROTAC degrader MI-389 synthesis, linked to cereblon and Boc.
    Formula:C24H32N4O6
    Color and Shape:Solid
    Molecular weight:472.542

    Ref: TM-T39512

    50mg
    To inquire
    100mg
    To inquire
  • Anticancer agent 204


    Anticanceragent 204 (Compound 6) is a fluorinated derivative of cinnamamides with anticancer activity. It can arrest the cell cycle of HepG2 cells in the G1 phase and induces apoptosis by reducing mitochondrial membrane polarization (MMP) levels.
    Formula:C26H18FN5O3S
    Molecular weight:499.11144

    Ref: TM-T209605

    10mg
    To inquire
    50mg
    To inquire
  • ECDD-S16


    ECDD-S16 is a potent inhibitor of pyroptosis. It effectively suppresses pyroptosis in Raw264.7 cells activated by surface and endosomal TLR ligands.
    Formula:C35H31FO12
    Molecular weight:662.17995

    Ref: TM-T208793

    10mg
    To inquire
    50mg
    To inquire
  • 3-Methoxy-9H-Carbazole

    CAS:
    3-methoxy-9H-carbazole: photosensitizer, anti-breast cancer, from Klauseneria spp., induces apoptosis.
    Formula:C13H11NO
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:197.23

    Ref: TM-T77681

    1mg
    60.00€
    5mg
    136.00€
    10mg
    197.00€
    25mg
    309.00€
    50mg
    408.00€
    100mg
    560.00€
    200mg
    750.00€
  • R1-ICR-5

    CAS:
    R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.
    Formula:C54H70N8O7S2
    Color and Shape:Solid
    Molecular weight:1007.31

    Ref: TM-T206654

    10mg
    To inquire
    50mg
    To inquire
  • MX106-4C


    MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.
    Formula:C23H25BrN2O2
    Molecular weight:440.10994

    Ref: TM-T209442

    10mg
    To inquire
    50mg
    To inquire
  • PROTAC GPX4 degrader-2


    PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.
    Formula:C50H61ClN8O9
    Molecular weight:952.425

    Ref: TM-T209085

    10mg
    To inquire
    50mg
    To inquire
  • Thalidomide-5-propargyne-NH2 hydrochloride

    CAS:
    Thalidomide derivative for CRBN protein recruitment, used in PROTACs production for protein degradation.
    Formula:C16H14ClN3O4
    Color and Shape:Solid
    Molecular weight:347.753

    Ref: TM-T40151

    100mg
    To inquire
    500mg
    To inquire
  • WEE1-IN-7


    WEE1-IN-7 (compound 12h) is a potent, orally active WEE1 inhibitor with an IC50 value of 2.1 nM. This compound induces apoptosis and causes cell cycle arrest in the S phase, demonstrating antitumor activity.

    Ref: TM-T210408

    10mg
    To inquire
    50mg
    To inquire
  • Anticancer agent 104


    Anticancer agent 104 has anticancer activity, and induces cancer cell apoptosis [1] .
    Formula:C34H47F3N2O2S2
    Color and Shape:Solid
    Molecular weight:636.87

    Ref: TM-T74795

    5mg
    To inquire
    50mg
    To inquire
  • TAS-117

    CAS:
    TAS-117, a PKB/Akt inhibitor, is used potentially for the treatment of solid tumors.
    Formula:C26H24N4O2
    Color and Shape:Solid
    Molecular weight:424.49

    Ref: TM-T28923

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Topoisomerase II inhibitor 17


    TopoisomeraseII inhibitor 17 (compound 4c) is a thiazolopyrimidine-based inhibitor of Topoisomerase II with an IC50 of 0.23 μM. This compound significantly disrupts the cell cycle and induces apoptosis.
    Formula:C25H22Cl3N3O5S
    Molecular weight:581.03458

    Ref: TM-T209153

    10mg
    To inquire
    50mg
    To inquire
  • S2/IAPinh


    S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).
    Formula:C52H75Cl2FN6O6S
    Molecular weight:1000.48299

    Ref: TM-T209534

    10mg
    To inquire
    50mg
    To inquire
  • Odoroside A

    CAS:
    Odoroside A, from Nerium oleander leaves, induces cancer cell death via ROS/p53, causing apoptosis and cell cycle arrest.
    Formula:C30H46O7
    Color and Shape:Solid
    Molecular weight:518.68

    Ref: TM-T75669

    5mg
    To inquire
    50mg
    To inquire
  • Ru-Poma


    Ru-Poma is an Ru(II)-based photosensitizer designed to enhance the efficacy of photodynamic therapy (PDT) against tumors resistant to Cisplatin. It targets Pomalidomide to partially degrade CRBN, inducing ferroptosis by increasing lipid peroxides and downregulating GPX4 and GAPDH expression. In A549 cells, Ru-Poma exhibits cytotoxicity with IC50 values of 18.46 μM in the dark and 0.37 μM under illumination.
    Formula:C89H75Cl2N11O11Ru·7H2O

    Ref: TM-T209925

    10mg
    To inquire
    50mg
    To inquire
  • Antimycobacterial agent-5


    Antimycobacterial agent-5 (compound 27) is an imidazopyridine amide compound that targets the Mycobacterium electron transport chain (ETC) respiratory CIII2CIV2 supercomplex. It acts on Mycobacterium smegmatis CIII2CIV2 with an IC50 of 441 nM.
    Formula:C25H34ClN3O
    Molecular weight:427.23904

    Ref: TM-T209574

    10mg
    To inquire
    50mg
    To inquire
  • Thalidomide-O-C4-COOH

    CAS:
    Thalidomide-O-C4-COOH is a synthetic E3 ligase linker derived from Thalidomide for PROTAC tech.
    Formula:C18H18N2O7
    Color and Shape:Solid
    Molecular weight:374.3447

    Ref: TM-T39643

    25mg
    1,018.00€
  • MRIA9

    CAS:
    MRIA9 inhibits SIK1/2/3 & PAK2/3 with IC50: SIK1 (516 nM), SIK2 (180 nM), SIK3 (127 nM); ATP-competitive.
    Formula:C24H22ClFN6O3
    Color and Shape:Solid
    Molecular weight:496.92

    Ref: TM-T36891

    5mg
    538.00€
    10mg
    858.00€
  • Bim BH3, Peptide IV

    CAS:
    This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins.
    Formula:C145H222N44O41S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3269.65

    Ref: TM-TP1611

    100mg
    To inquire
    500mg
    To inquire
  • PROTAC EGFR degrader 9

    CAS:

    PROTACEGFRdegrader 9 (Compound C6) is an orally active, CRBN-based PROTAC EGFR degrader. It has a DC50 of 10.2 nM and a Kd of 240.2 nM against EGFRL858R/T790M/C797S. PROTACEGFRdegrader 9 demonstrates effective degradation activity against various EGFR mutants while not affecting EGFRWT.

    Formula:C45H48F3N9O6S
    Molecular weight:899.98

    Ref: TM-T209870

    10mg
    To inquire
    50mg
    To inquire
  • PRMT5-IN-33


    PRMT5-IN-33 (compound A8) is a selective inhibitor of PRMT5 that competes with SAM, exhibiting an IC50 of 10.9 nM. It induces apoptosis and inhibits the proliferation of Z-138 and MOLM-13 cells, demonstrating antitumor activity.
    Formula:C25H24BrN5O3S
    Molecular weight:553.07832

    Ref: TM-T209135

    10mg
    To inquire
    50mg
    To inquire
  • Bcl-2-IN-4

    CAS:
    Bcl-2-IN-4: potent, selective, oral Bcl-2 inhibitor with 1.5 nM IC50, >200x selectivity over Bcl-xL.
    Formula:C46H50ClN9O7S
    Color and Shape:Solid
    Molecular weight:908.46

    Ref: TM-T74297

    5mg
    To inquire
    50mg
    To inquire
  • PDE4D inhibitor 1


    PDE4-IN-1 is a PDE4 inhibitor characterized by high potency (IC50: 8.6 nM) and superior selectivity over other PDE subtypes. This compound inhibits the release of inflammatory cytokines and chemokines. Additionally, PDE4-IN-1 significantly restores the damaged cAMP-CREB signaling pathway, inhibits proliferation, and promotes differentiation to reverse psoriasis formation.
    Color and Shape:Odour Solid

    Ref: TM-T206858

    10mg
    To inquire
    50mg
    To inquire
  • Fludarabine triphosphate

    CAS:
    Fludarabine triphosphate inhibits key enzymes, causing cell death.
    Formula:C10H15FN5O13P3
    Color and Shape:Solid
    Molecular weight:525.17

    Ref: TM-T40862

    25mg
    1,369.00€
  • tetrathiomolybdate

    CAS:
    Tetrathiomolybdate (TM) promotes the dimerization of the metal-binding domain (WLN4) of the cellular copper efflux protein ATP7B through its characteristic
    Formula:MoS4
    Color and Shape:Solid
    Molecular weight:224.2

    Ref: TM-T77774

    5mg
    To inquire
    50mg
    To inquire
  • MY-943


    MY-943, a potent inhibitor of tubulin polymerization and LSD1, exhibits anticancer properties by inducing G2/M phase arrest, promoting apoptosis, and
    Formula:C30H36N4O6S2
    Color and Shape:Solid
    Molecular weight:612.76

    Ref: TM-T78155

    5mg
    To inquire
    50mg
    To inquire
  • 3-Hydroxyterphenyllin

    CAS:
    3-Hydroxyterphenyllin from A. candidus is a fungal compound with antioxidant, anticancer, antibacterial, and antiviral effects.
    Formula:C20H18O6
    Color and Shape:Solid
    Molecular weight:354.35

    Ref: TM-T36000

    1mg
    400.00€
  • PROTAC GPX4 degrader-4

    CAS:
    PROTACGPX4 degrader-4 is a GPX4 PROTAC degrader with a DC50 of 5.32 nM. It inhibits the activity of cancer cell lines RT4, T24, and J82 with IC50 values of 0.09, 2.97, and 7.58 μM, respectively. This compound elevates lipid ROS levels and induces ferroptosis in T24 and RT4 cells. In T24 tumor-bearing BALB/c nude mouse models, PROTACGPX4 degrader-4 demonstrates antitumor activity. It is applicable to bladder cancer research.
    Formula:C43H58N2O13
    Color and Shape:Solid
    Molecular weight:810.93

    Ref: TM-T207431

    10mg
    To inquire
    50mg
    To inquire
  • FR900359

    CAS:
    FR900359 is a macrocyclic Gq protein inhibitor that inhibits melanoma cell proliferation and can be used to study asthma, inflammation and cancer.
    Formula:C49H75N7O15
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1002.16

    Ref: TM-T27387

    1mg
    1,198.00€
  • Petromurin C

    CAS:
    Petromurin C, a bis-indolyl benzenoid from P. muricatus, is cytotoxic to NS-1 cells (IC50=33μg/ml) and active against T. foetus (IC50=100μg/ml).
    Formula:C26H24N2O5
    Color and Shape:Solid
    Molecular weight:444.487

    Ref: TM-T35910

    2500µg
    1,215.00€
  • MS105

    CAS:
    MS105 is an orally active, selective protein tyrosine kinase 6 (PTK6) PROTAC degrader. It recruits the VHL E3 ligase through a VHL ligand fragment, facilitating ubiquitination and proteasomal degradation of PTK6, thereby inhibiting the proliferation and migration of breast cancer cells and inducing apoptosis (apoptosis). MS105 is a promising compound for breast cancer research.
    Formula:C56H70FN13O6S
    Color and Shape:Solid
    Molecular weight:1072.30

    Ref: TM-T207347

    10mg
    To inquire
    50mg
    To inquire
  • Vinepidine sulfate

    CAS:
    Vinepidine (LY-119863) sulfate, a derivative of vincristine, exhibits antitumor activity .
    Formula:C46H58N4O13S
    Color and Shape:Solid
    Molecular weight:907.04

    Ref: TM-T88271

    10mg
    To inquire
    50mg
    To inquire
  • Diprovocim-1

    CAS:
    Diprovocim-1: TLR1/2 agonist; triggers TNF-α in THP-1 cells; boosts ovalbumin IgG1 & CTLs against tumors with anti-PD-L1 in mice.
    Formula:C56H56N6O6
    Color and Shape:Solid
    Molecular weight:909.1

    Ref: TM-T37722

    1mg
    239.00€
    5mg
    593.00€
    10mg
    1,018.00€
  • Tubulin polymerization-IN-67


    Tubulin polymerization-IN-67 (Compound 5h) serves as an inhibitor of microtubule protein polymerization at the colchicine binding site, exhibiting an IC50 value of 2.92 μM. It effectively inhibits the proliferation of various cancer cell lines including HT29, A549, U2OS, MG-63, and HeLa, with IC50 values ranging from 0.12 to 4.13 μM. Additionally, Tubulin polymerization-IN-67 induces cell cycle arrest at the G2/M phase and triggers apoptosis in U2OS cells. It also inhibits cell migration in A549 and reduces mitochondrial membrane potential (MMP) while increasing intracellular ROS levels, thereby suppressing angiogenesis in HUVEC cells. Furthermore, this compound demonstrates antitumor activity in mice.
    Color and Shape:Odour Solid

    Ref: TM-T89235

    10mg
    To inquire
    50mg
    To inquire
  • Pipermethystine


    Pipermethystine is a useful organic compound for research related to life sciences and the catalog number is T124340.
    Formula:C16H17NO4
    Color and Shape:Solid
    Molecular weight:287.315

    Ref: TM-T124340

    1mg
    To inquire
    5mg
    To inquire
  • Antiproliferative agent-42


    Antiproliferative Agent-42 (Compound 7m), a dihydrodipyrrolo compound, exhibits antiproliferative activity against the Panc-1 cell line, with an IC 50 of 12.54
    Color and Shape:Odour Solid

    Ref: TM-T83015

    5mg
    To inquire
    50mg
    To inquire
  • Beclin1-Bcl-2 interaction inhibitor 1


    Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].
    Color and Shape:Odour Solid

    Ref: TM-T82902

    5mg
    To inquire
    50mg
    To inquire
  • Ac-FEID-CMK


    Ac-FEID-CMK: Potent inhibitor for zebrafish GSDMEb, reduces pyroptosis, and lessens septic AKI.
    Formula:C27H37ClN4O9
    Color and Shape:Solid
    Molecular weight:597.06

    Ref: TM-T76251

    5mg
    To inquire
    50mg
    To inquire
  • Azalamellarin N

    CAS:
    Azalamellarin N is a pyroptosis inhibitor that exhibits varying inhibitory effects on different pyroptosis inducers. It functions by targeting molecules upstream of NLRP3 inflammasome activation, instead of directly affecting the components of the NLRP3 inflammasome. Its inhibitory potency against various inducers is ranked as follows: Nigericin > R837 [1].
    Formula:C28H22N2O7
    Color and Shape:Solid
    Molecular weight:498.48

    Ref: TM-T85784

    25mg
    2,840.00€
    50mg
    4,104.00€
    100mg
    5,169.00€
  • Trilexium

    CAS:
    Trilexium (TRX-E-009-1), a third-generation benzopyran structurally related to TRX-E-002-1, increases p21 protein expression, induces apoptosis, depolymerizes microtubules, and demonstrates broad anti-cancer activity [1] [2].
    Formula:C24H23FO6
    Color and Shape:Solid
    Molecular weight:426.43

    Ref: TM-T87565

    10mg
    To inquire
    50mg
    To inquire
  • Barasertib

    CAS:
    AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
    Formula:C26H31FN7O6P
    Purity:99.92% - 99.97%
    Color and Shape:Solid
    Molecular weight:587.54

    Ref: TM-T14371

    2mg
    47.00€
    5mg
    71.00€
    10mg
    110.00€
    25mg
    197.00€
    50mg
    348.00€
    1mL*10mM (DMSO)
    93.00€
  • XIAP BIR2/BIR2-3 inhibitor-1

    CAS:
    XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].
    Formula:C72H96N16O14
    Color and Shape:Solid
    Molecular weight:1409.63

    Ref: TM-T87640

    10mg
    To inquire
    50mg
    To inquire
  • Azurin p28 peptide

    CAS:

    Azurin p28 peptide, a tumor-penetrating antitumor agent, stabilizes p53 by reducing its proteasomal degradation via the formation of a p28:p53 complex.

    Formula:C122H197N31O47S2
    Color and Shape:Solid
    Molecular weight:2914.18

    Ref: TM-T80523

    5mg
    To inquire
    50mg
    To inquire
  • PD-1/PD-L1-IN-48


    PD-1/PD-L1-IN-48 (compound HD10) is an effective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 3.1 nM. It plays a vital role in cancer research.
    Color and Shape:Odour Solid

    Ref: TM-T89108

    10mg
    To inquire
    50mg
    To inquire
  • BcI-2/BcI-xI ligand 1

    CAS:
    BcI-2/BcI-xI ligand 1, functioning as a BcI-2/BcI-xI ligand, is utilized in the synthesis of PROTAC BcI-2/BcI-xI Degrader-1 .
    Formula:C53H64ClF3N6O8S3
    Color and Shape:Solid
    Molecular weight:1101.75

    Ref: TM-T88278

    10mg
    To inquire
    50mg
    To inquire
  • Necroptosis-IN-4


    Necroptosis-IN-4 is an effective inhibitor of necroptosis, specifically targeting RIP kinase 1 (RIPK1) without inhibitory activity against RIPK3. It exhibits weak inhibitory effects on VEGFR1/2 and PDGFR-α.
    Color and Shape:Odour Solid

    Ref: TM-T89380

    10mg
    To inquire
    50mg
    To inquire
  • 5-Fluorouracil-13C,15N2

    CAS:
    5-Fluorouracil-13C,15N2 is a standard for quantifying 5-fluorouracil via GC/LC-MS and blocks DNA synthesis, causing cell apoptosis.
    Formula:C4H3FN2O2
    Color and Shape:Solid
    Molecular weight:133.057

    Ref: TM-T36895

    1mg
    755.00€
  • RET Ligand-Linker Conjugate-1


    RET Ligand-Linker Conjugate-1 consists of a complex formed by a RET ligand and a linker, which can be utilized in the synthesis of QZ2135.
    Formula:C40H44N10O
    Color and Shape:Solid
    Molecular weight:680.84

    Ref: TM-T205264

    10mg
    To inquire
    50mg
    To inquire
  • Necroptosis-IN-5


    Necroptosis-IN-5 (Compound 26) is an orally active inhibitor of necroptotic cell death (necroptosis). This compound also exhibits potent inhibitory activity against receptor-interacting protein kinase 1 (RIPK1). It can be utilized in research related to inflammatory diseases, neurodegenerative disorders, and cancer associated with necroptosis.
    Color and Shape:Odour Solid

    Ref: TM-T89312

    10mg
    To inquire
    50mg
    To inquire
  • EGFR/DHFR-IN-2


    EGFR/DHFR-IN-2 (9b) is a dual inhibitor of h-DHFR/EGFR TK, exhibiting IC50 values of 0.192 μM for h-DHFR and 0.109 μM for EGFR. It causes cell cycle arrest at the G1/S phase and induces apoptosis. Additionally, EGFR/DHFR-IN-2 (9b) is a potential inhibitor of CYP2C9 and CYP3A4. This compound can be utilized in cancer research.
    Formula:C24H16N4O5
    Color and Shape:Solid
    Molecular weight:440.11207

    Ref: TM-T207349

    10mg
    To inquire
    50mg
    To inquire
  • PBE-AMF


    PBE-AMF is a prodrug that activates H2O2 and exhibits anticancer activity. It impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing cell death (apoptosis), and blocking the cell cycle. PBE-AMF effectively and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 μM) while sparing non-cancerous MCF-10A cells.
    Color and Shape:Odour Solid

    Ref: TM-T88991

    10mg
    To inquire
    50mg
    To inquire
  • FOXO4-DRI

    CAS:
    FOXO4-DRI: a peptide blocking FOXO4/p53 interaction; induces senescent cells' apoptosis.
    Formula:C228H388N86O64
    Color and Shape:Solid
    Molecular weight:5358.06

    Ref: TM-T76563

    5mg
    To inquire
    50mg
    To inquire
  • TNF-α Antagonist

    CAS:
    TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with
    Formula:C58H71N11O15S2
    Color and Shape:Solid
    Molecular weight:1226.39

    Ref: TM-T36127

    1mg
    792.00€
    5mg
    3,307.00€
    500µg
    408.00€
  • Antagonist G TFA


    Potent vasopressin blocker, Antagonist G TFA also mildly inhibits GRP & Bradykinin, triggers AP-1, enhances chemo response.
    Formula:C51H67F3N12O8S
    Color and Shape:Solid
    Molecular weight:1065.21

    Ref: TM-T75834

    5mg
    To inquire
    50mg
    To inquire
  • (E/Z)-Eltrombopag 13C4

    CAS:
    (E/Z)-Eltrombopag 13C4 is a mix of E/Z isotopologues, both 13C-labeled TPO receptor agonists for thrombocytopenia.
    Formula:C25H22N4O4
    Color and Shape:Solid
    Molecular weight:446.444

    Ref: TM-T38602

    1mg
    299.00€
    5mg
    To inquire
    10mg
    To inquire
  • Endoplasmic Reticulum Stress Compound Library


    A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
    Color and Shape:Odour Solid

    Ref: TM-L9700

    1mg
    To inquire
    30μL*10mM (DMSO)
    To inquire
    50μL*10mM (DMSO)
    To inquire
    100μL*10mM (DMSO)
    To inquire
    250μL*10mM (DMSO)
    To inquire
  • Varlilumab

    CAS:
    Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.
    Purity:SDS-PAGE:95% SEC-HPLC:98.65%
    Color and Shape:Liquid
    Molecular weight:146 kDa

    Ref: TM-T76706

    1mg
    200.00€
    5mg
    485.00€
    10mg
    802.00€
    25mg
    1,215.00€
    50mg
    1,639.00€
  • XIAP BIR2/BIR2-3 inhibitor-3

    CAS:
    XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].
    Formula:C86H106N18O16S2
    Color and Shape:Solid
    Molecular weight:1712

    Ref: TM-T87642

    10mg
    To inquire
    50mg
    To inquire
  • Cot inhibitor-1 hydrochloride


    Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.
    Formula:C27H28Cl3FN8
    Purity:98.37%
    Color and Shape:Soild
    Molecular weight:589.92

    Ref: TM-T10865L

    1mg
    118.00€
    5mg
    227.00€
    10mg
    359.00€
    25mg
    598.00€
    50mg
    852.00€
    100mg
    1,153.00€
    1mL*10mM (DMSO)
    268.00€
  • 4-Nitrothalidomide

    CAS:
    4-Nitrothalidomide is a modified form of thalidomide that inhibits the growth and proliferation of HUVEC cells and is commonly used in the synthesis of pomalidomide, which has anticancer potential.
    Formula:C13H9N3O6
    Purity:99.94%
    Color and Shape:Solid
    Molecular weight:303.23

    Ref: TM-T206043

    50mg
    63.00€
    100mg
    94.00€
  • p-MPPF

    CAS:
    p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.
    Formula:C25H27FN4O2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:434.51

    Ref: TM-T69750L

    1mg
    201.00€
    5mg
    497.00€
    10mg
    701.00€
    25mg
    1,094.00€
    50mg
    1,508.00€
    100mg
    1,931.00€
  • CIGB-300

    CAS:
    CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by disrupting the phosphorylation activity of protein kinase CK2. The compound induces apoptosis in various tumor cell lines, making it valuable for research in cancer therapy.
    Formula:C127H215N53O30S3
    Color and Shape:Solid
    Molecular weight:3060.6

    Ref: TM-TP2765

    10mg
    To inquire
    50mg
    To inquire
  • MMRi62

    CAS:
    MMRi62, a MDM2-MDM4 inhibitor, induces ferroptosis and autophagy in PDAC, degrades FTH1 and mutant p53, and inhibits KRAS/TP53 mutant PDAC in mice.
    Formula:C21H15Cl2N3O
    Purity:99.87%
    Color and Shape:Soild
    Molecular weight:396.27

    Ref: TM-T60202

    1mg
    35.00€
    5mg
    70.00€
    10mg
    104.00€
    25mg
    202.00€
    50mg
    329.00€
    100mg
    525.00€
    500mg
    1,121.00€
    1mL*10mM (DMSO)
    78.00€
  • Ac-Trp-Glu-His-Asp-Aldehyde

    CAS:
    Ac-Trp-Glu-His-Asp-Aldehyde is a powerful and selective inhibitor of caspase-1, demonstrating a K_i value of 56 pM [1] [2].
    Formula:C28H33N7O9
    Color and Shape:Solid
    Molecular weight:611.6

    Ref: TM-T76600

    5mg
    To inquire
    50mg
    To inquire
  • Reproxalap

    CAS:

    Reproxalap (NS-2) is a dry eye treatment that neutralizes aldehydes like malondialdehyde.

    Formula:C12H13ClN2O
    Purity:99.4% - 99.97%
    Color and Shape:Solid
    Molecular weight:236.7

    Ref: TM-T16732

    5mg
    39.00€
    10mg
    52.00€
    25mg
    97.00€
    50mg
    169.00€
    100mg
    264.00€
  • YX0798


    YX0798 is a selective, orally active CDK9 inhibitor (Kd: 0.28 nM). It downregulates the oncogenic protein c-MYC and the pro-survival protein MCL-1. YX0798 disrupts the cell cycle and causes transcriptome reprogramming, ultimately leading to apoptosis. The compound exhibits antitumor activity.
    Formula:C21H19ClF3N5O2
    Color and Shape:Solid
    Molecular weight:465.86

    Ref: TM-T207141

    10mg
    To inquire
    50mg
    To inquire
  • Anti-inflammatory agent 35

    CAS:
    Anti-inflammatory agent 35 is a potent anti-inflammatory agent.
    Formula:C27H29NO8
    Purity:99.98%
    Color and Shape:Soild
    Molecular weight:495.52

    Ref: TM-T64358

    5mg
    43.00€
    10mg
    60.00€
    25mg
    110.00€
    50mg
    180.00€
    100mg
    289.00€
    1mL*10mM (DMSO)
    49.00€
  • Apoptosis inducer 32


    Apoptosisinducer 32 (Compound 7g) is an apoptosis inducer with a KD of 42 μM, demonstrating antitumor activity by causing significant morphological changes, such as membrane blebbing, nuclear fragmentation, and apoptotic body formation, in MDA-MB-231 cells. The IC50 values for Apoptosisinducer 32 are 4.77 μM in MCF-7 cells, 6.56 μM in MDA-MB-231 cells, and 337.8 μM in HEK cells.
    Formula:C29H27Cl2N3O8
    Color and Shape:Solid
    Molecular weight:616.45

    Ref: TM-T203355

    10mg
    To inquire
    50mg
    To inquire
  • PD-L1 inhibitory peptide

    CAS:
    PD-L1inhibitory peptide is an inhibitor peptide that targets the programmed cell death ligand 1 (PD-L1). By binding to PD-L1, it lifts immune suppression and restores the anti-tumor activity of T cells. PD-L1inhibitory peptide holds promise for use in tumor research.
    Formula:C96H135N21O23S
    Color and Shape:Solid
    Molecular weight:1983.29

    Ref: TM-T207654

    10mg
    To inquire
    50mg
    To inquire
  • FL118

    CAS:
    FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits
    Formula:C21H16N2O6
    Purity:97.14%
    Color and Shape:Soild
    Molecular weight:392.36

    Ref: TM-T77701

    1mg
    75.00€
    5mg
    145.00€
    10mg
    177.00€
    25mg
    356.00€
    50mg
    439.00€
    100mg
    708.00€
  • RIPK1-IN-25


    RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.
    Color and Shape:Odour Solid

    Ref: TM-T200657

    10mg
    To inquire
    50mg
    To inquire
  • Carbonic anhydrase inhibitor 33


    Carbonic anhydrase inhibitor33 (11D) is a dual inhibitor that targets both CA (carbonic anhydrase) IX/XII and CDK6. It exhibits Ki values of 19.7 nM for hCA IX and 26.1 nM for hCA XII. Additionally, Carbonic anhydrase inhibitor33 (11D) can induce G1 phase cell cycle arrest and apoptosis, making it relevant for research in non-small cell lung cancer (NSCLC).
    Formula:C19H15FN6O2S
    Color and Shape:Solid
    Molecular weight:410.09612

    Ref: TM-T207227

    10mg
    To inquire
    50mg
    To inquire
  • CDK2-IN-45


    CDK2-IN-45 is a CDK2 inhibitor with an IC50 value of 0.64 μM. It effectively inhibits the proliferation of DU-145 and PC-3 cell lines, with IC50 values of 2.20 μM and 4.17 μM, respectively. Additionally, CDK2-IN-45 induces G0/G1 phase cell cycle arrest and apoptosis. It is utilized in prostate cancer research.
    Formula:C25H16ClN5S
    Color and Shape:Solid
    Molecular weight:453.95

    Ref: TM-T207142

    10mg
    To inquire
    50mg
    To inquire
  • PI3K-AKT-mTOR Compound Library


    A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with
    Color and Shape:Odour Solid

    Ref: TM-L1300

    1mg
    To inquire
    30μL*10mM (DMSO)
    To inquire
    50μL*10mM (DMSO)
    To inquire
    100μL*10mM (DMSO)
    To inquire
    250μL*10mM (DMSO)
    To inquire
  • Necroptosis-IN-3

    CAS:
    Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.
    Formula:C12H17NOS
    Purity:99.85%
    Color and Shape:Soild
    Molecular weight:223.33

    Ref: TM-T64349

    25mg
    50.00€
    50mg
    77.00€
    100mg
    104.00€
    200mg
    170.00€
    1mL*10mM (DMSO)
    33.00€