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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6170 products of "Apoptosis"

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  • Zeluvalimab

    CAS:
    Zeluvalimab (AMG-404) is a monoclonal antibody designed to target the PD-1 receptor, and is utilized in cancer research [1].
    Color and Shape:Liquid

    Ref: TM-T77187

    5mg
    To inquire
  • Telitacicept

    CAS:
    Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand
    Color and Shape:Liquid

    Ref: TM-T78309

    1mg
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    5mg
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  • HDAC6-IN-22


    HDAC6-IN-22 (compound 30), an HDAC6 inhibitor, exhibits an IC50 of 4.63 nM and demonstrates antiproliferative effects against multiple myeloma both in vitro and
    Formula:C24H24N4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:400.47

    Ref: TM-T79771

    5mg
    To inquire
    50mg
    To inquire
  • Thalidomide-O-C6-NH2

    CAS:
    Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].
    Formula:C19H23N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:373.4

    Ref: TM-T18825

    100mg
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    500mg
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  • Rozibafusp alfa

    CAS:
    Rozibafusp alfa is an IgG2-κ antibody that targets ICOSLG, combined with a TNFSF13B fusion protein [1].
    Color and Shape:Liquid

    Ref: TM-T81256

    1mg
    To inquire
    5mg
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  • BcI-2/BcI-xI ligand 1

    CAS:
    BcI-2/BcI-xI ligand 1, functioning as a BcI-2/BcI-xI ligand, is utilized in the synthesis of PROTAC BcI-2/BcI-xI Degrader-1 .
    Formula:C53H64ClF3N6O8S3
    Color and Shape:Solid
    Molecular weight:1101.75

    Ref: TM-T88278

    10mg
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    50mg
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  • PROTAC GPX4 degrader-1

    CAS:
    PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080
    Formula:C50H57ClN10O10
    Color and Shape:Solid
    Molecular weight:993.5

    Ref: TM-T74796

    5mg
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    50mg
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  • 2,2'-Dihydroxy chalcone

    CAS:
    2,2'-Dihydroxy chalcone inhibits β-glucuronidase (IC50=1.6 μM) and lysozyme (IC50=1.4 μM), and fights E. coli, S. fowleri, S. albicans, S. aureus.
    Formula:C15H12O3
    Purity:99.70%
    Color and Shape:Solid
    Molecular weight:240.25

    Ref: TM-TN7224

    1mg
    85.00€
    5mg
    168.00€
    10mg
    240.00€
    25mg
    371.00€
    50mg
    513.00€
    100mg
    687.00€
    200mg
    928.00€
  • Pyridinium bisretinoid A2E

    CAS:
    Pyridinium bisretinoid A2E (A2E) is a fluorescent molecule isolated from the lipofuscin of retinal pigment epithelium, a weak photosensitizer.
    Formula:C42H58NO
    Purity:83.65%
    Color and Shape:Solid
    Molecular weight:592.92

    Ref: TM-T74051

    1mg
    839.00€
  • Z-Asp-CH2-DCB

    CAS:
    Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.
    Formula:C20H17Cl2NO7
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:454.26

    Ref: TM-T13378

    10mg
    43.00€
    25mg
    To inquire
    50mg
    To inquire
  • Anti-Mouse PD-1 Antibody (D265A) Antibody (RMP1-14)


    Anti-MousePD-1Antibody (D265A) is an antibody inhibitor targeting the PD-1 protein in mice.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-812

    1mg
    160.00€
    5mg
    537.00€
    10mg
    To inquire
  • β-Glucuronide-dPBD-PEG5-NH2 TFA

    CAS:
    β-Glucuronide-dPBD-PEG5-NH2 TFA is a β-glucuronide-linked pyrrolobenzodiazepine dimer employed in the synthesis of the antibody-drug conjugate (ADC) cIRCR201-
    Formula:C80H102F3N7O37
    Color and Shape:Solid
    Molecular weight:1810.69

    Ref: TM-T74438

    5mg
    To inquire
    50mg
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  • Beclin1-Bcl-2 interaction inhibitor 1


    Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].
    Color and Shape:Odour Solid

    Ref: TM-T82902

    5mg
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    50mg
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  • Sincalide ammonium

    CAS:
    Sincalide ammonium, a CCK analog, stimulates bile release, gallbladder contraction, and sphincter relaxation, aiding in diagnoses.
    Formula:C49H65N11O16S3
    Purity:98.46%
    Color and Shape:Solid
    Molecular weight:1160.3

    Ref: TM-TP1198

    1mg
    93.00€
    5mg
    222.00€
    10mg
    358.00€
    25mg
    587.00€
    50mg
    822.00€
    100mg
    1,108.00€
    500mg
    2,215.00€
  • 1,2-Naphthoquinone

    CAS:
    1,2-Naphthoquinone inhibits urease, induces apoptosis in PBMC cells, inhibitory activity against hiCE, hCE1, hAChE, and hBChE.
    Formula:C10H6O2
    Purity:98.01%
    Color and Shape:Golden Yellow Needles Color On Standing (Ntp 1992)
    Molecular weight:158.15

    Ref: TM-T20410

    25mg
    38.00€
    50mg
    52.00€
    100mg
    66.00€
  • Antiproliferative agent-42


    Antiproliferative Agent-42 (Compound 7m), a dihydrodipyrrolo compound, exhibits antiproliferative activity against the Panc-1 cell line, with an IC 50 of 12.54
    Color and Shape:Odour Solid

    Ref: TM-T83015

    5mg
    To inquire
    50mg
    To inquire
  • Lesigercept


    Lesigercept is a humanized antibody that targets IGHE.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-374

    1mg
    To inquire
    5mg
    To inquire
  • RIPK2/3-IN-1


    RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3.
    Formula:C24H16N4O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:456.54

    Ref: TM-T79352

    5mg
    To inquire
    50mg
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  • Thalidomide-Piperazine-Piperidine

    CAS:
    Thalidomide-based E3 ligase ligand linked to a PROTAC piperazine-piperidine chain.
    Formula:C22H27N5O4
    Color and Shape:Solid
    Molecular weight:425.489

    Ref: TM-T39711

    5mg
    323.00€
    10mg
    537.00€
    25mg
    1,020.00€
  • icFSP1

    CAS:
    icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
    Formula:C26H25N3O5
    Purity:99.87% - 99.93%
    Color and Shape:Soild
    Molecular weight:459.49

    Ref: TM-T77344

    1mg
    261.00€
    5mg
    597.00€
    10mg
    837.00€
    25mg
    1,179.00€
    50mg
    1,476.00€
    100mg
    1,795.00€
  • EMB-02


    EMB-02 is a bispecific antibody targeting both PD-1 and LAG-3. It inhibits the downregulation of T cell activation and proliferation mediated by PD-1 and LAG-3, showing potent anti-cancer properties.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-799

    1mg
    To inquire
    5mg
    To inquire
  • (-)-Irofulven

    CAS:
    Irofulven is an agent of DNA-damaging and antitumor. It is used for the treatment of advanced solid tumors, including prostate, ovarian, and pancreatic cancers.
    Formula:C15H18O3
    Color and Shape:Solid
    Molecular weight:246.30

    Ref: TM-T24176

    25mg
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    50mg
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    100mg
    To inquire
  • YT117R


    YT117R is a PROTAC that targets degradation of FKBP12 and BRD4.
    Formula:C50H52ClN9O7S
    Color and Shape:Solid
    Molecular weight:958.52

    Ref: TM-T200965

    10mg
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    50mg
    To inquire
  • DAPK-IN-2

    CAS:
    DAPK-IN-2: DAPK inhibitor with anticancer potential. Used in cerebral infarction and ischemia research.
    Formula:C17H14N2O4
    Purity:97.36%
    Color and Shape:Solid
    Molecular weight:310.3

    Ref: TM-T77611

    1mg
    44.00€
    5mg
    89.00€
    10mg
    138.00€
    25mg
    224.00€
    50mg
    298.00€
    100mg
    404.00€
    200mg
    542.00€
  • Pipermethystine


    Pipermethystine is a useful organic compound for research related to life sciences and the catalog number is T124340.
    Formula:C16H17NO4
    Color and Shape:Solid
    Molecular weight:287.315

    Ref: TM-T124340

    1mg
    To inquire
    5mg
    To inquire
  • YL-5092

    CAS:
    YL-5092, YTHDC1 inhibitor (IC50=7.4 nM), induces G0/G1 arrest and apoptosis, used for acute myeloid leukemia (AML).
    Formula:C22H14F3N3O2S
    Color and Shape:Solid
    Molecular weight:441.43

    Ref: TM-T200229

    10mg
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    50mg
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  • Ac-AAVALLPAVLLALLAP-DEVD-CHO

    CAS:
    Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) serves as a potent and reversible inhibitor of caspase-3 [1].
    Formula:C94H158N20O27
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2000.38

    Ref: TM-T80531

    5mg
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    50mg
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  • Anti-PD-L1/B7-H1 Antibody (29E.2A3)


    Anti-PD-L1/B7-H1 Antibody (29E.2A3) represents a chimeric antibody of mouse IgG2b, κ type, specifically targeting human PD-L1/B7-H1. The recommended isotype control for this antibody is Mouse IgG2b kappa, Isotype Control.

    Ref: TM-T9901A-110

    1mg
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    5mg
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  • PARP1-IN-15


    PARP1-IN-15 (Compound 6) is a PARP1 inhibitor that also inhibits tankyrase (TNKS) and promotes DNA double-strand breaks, leading to tumor cell apoptosis.
    Formula:C16H12N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:264.28

    Ref: TM-T79405

    5mg
    To inquire
    50mg
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  • COG-1410 acetate


    COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.
    Formula:C66H125N21O16
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:1468.83

    Ref: TM-T30998L

    1mg
    105.00€
    5mg
    268.00€
    10mg
    447.00€
    25mg
    713.00€
    50mg
    1,018.00€
    100mg
    1,369.00€
    500mg
    2,673.00€
  • PD-1/PD-L1-IN-52


    PD-1/PD-L1-IN-52 (Compound Ⅲ-5) is an orally active inhibitor of PD-1/PD-L1 interaction, exhibiting an IC50 of 109.9 nM. It demonstrates antitumor activity in a C57BL/6 mouse model of MC38 colon carcinoma cells expressing human PD-1, achieving a tumor growth inhibition (TGI) rate of 49.6%.
    Color and Shape:Odour Solid

    Ref: TM-T200724

    10mg
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    50mg
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  • Ac-AAVALLPAVLLALLAP-LEHD-CHO

    CAS:
    Ac-AAVALLPAVLLALLAP-LEHD-CHO is a caspase inhibitor targeting caspases 4, 5, and 9, demonstrating protective effects in MCF-7 cells treated with
    Formula:C97H162N22O25
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2036.46

    Ref: TM-T80537

    5mg
    To inquire
    50mg
    To inquire
  • ATPase-IN-3

    CAS:
    ATPase-IN-3 is an ATPase (ATPase) inhibitor that can be used in the study of metabolism-related diseases.
    Formula:C10H6N2O3S2
    Purity:97.76%
    Color and Shape:Soild
    Molecular weight:266.3

    Ref: TM-T83967

    2mg
    35.00€
    5mg
    52.00€
    10mg
    74.00€
    25mg
    140.00€
    50mg
    210.00€
    100mg
    309.00€
    200mg
    462.00€
  • S-Adenosyl-L-methionine iodide

    CAS:
    S-(5'-Adenosyl)-L-methionine iodide, also known as S-Adenosyl-L-methionine iodide, is a vital methyl donor present in all living organisms [1].
    Formula:C15H23IN6O5S
    Color and Shape:Solid
    Molecular weight:526.35

    Ref: TM-T74497

    5mg
    To inquire
    50mg
    To inquire
  • Mas7

    CAS:
    Amphiphilic peptide Mas7, a structural analogue of mastoparan is a known activator of heterotrimeric Gi-proteins and its downstream effectors.
    Formula:C67H124N18O15
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1421.81

    Ref: TM-TP1107

    1mg
    88.00€
    5mg
    319.00€
    10mg
    497.00€
    25mg
    842.00€
  • PD-1/PD-L1-IN-51


    PD-1/PD-L1-IN-51 (Compound III-4) is an inhibitor of PD-1/PD-L1 (IC50: hPD-L1 at 2.9 nM). It binds directly to PD-L1, blocking the interaction between PD-1 and PD-L1, and enhancing the release of IFN-γ. Additionally, PD-1/PD-L1-IN-51 exhibits antitumor activity.
    Color and Shape:Odour Solid

    Ref: TM-T200579

    10mg
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    50mg
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  • CPTH2 (hydrochloride) (357649-93-5 free base)

    CAS:
    CPTH2 is an inhibitor of the HAT activity of Gcn5.
    Formula:C14H15Cl2N3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:328.26

    Ref: TM-T22693

    5mg
    316.00€
    10mg
    416.00€
  • Thalidomide-5-propoxyethanamine

    CAS:
    Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of recruiting the CRBN protein.
    Formula:C18H21N3O5
    Color and Shape:Solid
    Molecular weight:359.38

    Ref: TM-T39892

    25mg
    1,369.00€
  • 1-Alaninechlamydocin

    CAS:

    1-Alaninechlamydocin, a fungal metabolite from Tolypocladium sp., inhibits HDACs and reduces cell proliferation with GI50s 5.3-14 nM.

    Formula:C27H36N4O6
    Color and Shape:Solid
    Molecular weight:512.607

    Ref: TM-T36797

    5mg
    6,631.00€
  • p53 and MDM2 proteins-interaction-inhibitor (racemic)

    CAS:
    p53 and MDM2 proteins-interaction-inhibitor (racemic) is an inhibitor of the interaction between p53 and MDM2 proteins.
    Formula:C40H49Cl2N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:734.75

    Ref: TM-T12351

    25mg
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    50mg
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    100mg
    To inquire
  • PD-1/PD-L1-IN-50


    Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.
    Color and Shape:Odour Solid

    Ref: TM-T200687

    10mg
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    50mg
    To inquire
  • Methyl-4-oxoretinoate

    CAS:
    Methyl-4-oxoretinoate is a synthetic retinoid with anticancer properties, used for skin conditions and potential ocular treatments.
    Formula:C21H28O3
    Purity:99.95%
    Color and Shape:Solid
    Molecular weight:328.45

    Ref: TM-T77600

    10mg
    39.00€
    25mg
    66.00€
    50mg
    92.00€
    100mg
    147.00€
  • PF-543

    CAS:
    PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.
    Formula:C27H31NO4S
    Purity:99.02%
    Color and Shape:Solid
    Molecular weight:465.6

    Ref: TM-T6085

    1mg
    38.00€
    5mg
    80.00€
    10mg
    105.00€
    25mg
    222.00€
    50mg
    334.00€
    1mL*10mM (DMSO)
    82.00€
  • Compound TPX-0046

    CAS:
    Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.
    Formula:C21H21FN6O3
    Purity:99.94%
    Color and Shape:Soild
    Molecular weight:424.43

    Ref: TM-T67779

    1mg
    79.00€
    5mg
    133.00€
    10mg
    190.00€
    25mg
    306.00€
    50mg
    414.00€
    100mg
    532.00€
  • MY-943


    MY-943, a potent inhibitor of tubulin polymerization and LSD1, exhibits anticancer properties by inducing G2/M phase arrest, promoting apoptosis, and
    Formula:C30H36N4O6S2
    Color and Shape:Solid
    Molecular weight:612.76

    Ref: TM-T78155

    5mg
    To inquire
    50mg
    To inquire
  • 3-Hydroxyterphenyllin

    CAS:
    3-Hydroxyterphenyllin from A. candidus is a fungal compound with antioxidant, anticancer, antibacterial, and antiviral effects.
    Formula:C20H18O6
    Color and Shape:Solid
    Molecular weight:354.35

    Ref: TM-T36000

    1mg
    400.00€
  • PD-1/PD-L1 inhibitory peptide C8


    PD-1/PD-L1 inhibitory peptide C8 disrupts the PD-1/PD-L1 interaction, leading to the activation of CD8+ and CD4+ T cells and an increase in IFN-γ secretion. In mouse models, PD-1/PD-L1 inhibitory peptide C8 has demonstrated antitumor activity.
    Formula:C51H72N14O14S2
    Color and Shape:Solid
    Molecular weight:1169.33

    Ref: TM-TP3029

    10mg
    To inquire
    50mg
    To inquire
  • PD-1/PD-L1-IN-9

    CAS:
    PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction.
    Formula:C22H24N2O2
    Purity:99.92%
    Color and Shape:Solid
    Molecular weight:348.44

    Ref: TM-T9651

    1mg
    57.00€
    2mg
    85.00€
    5mg
    127.00€
    10mg
    178.00€
    25mg
    298.00€
    50mg
    405.00€
    100mg
    535.00€
    500mg
    1,063.00€
    1mL*10mM (DMSO)
    140.00€
  • GGTI298 Trifluoroacetate

    CAS:
    GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.
    Formula:C27H33N3O3S·C2HF3O2
    Purity:98.07% - >99.99%
    Color and Shape:Solid
    Molecular weight:593.66

    Ref: TM-T6844

    1mg
    82.00€
    5mg
    150.00€
    10mg
    227.00€
    25mg
    442.00€
    50mg
    615.00€
    1mL*10mM (DMSO)
    192.00€
  • Satratoxin H

    CAS:
    Satratoxin H is an air- and food-borne mycotoxin, which has been implicated in human health damage.
    Formula:C29H36O9
    Color and Shape:Solid
    Molecular weight:528.598

    Ref: TM-T34536

    1mg
    712.00€
    5mg
    3,312.00€
    500µg
    386.00€
  • BY13


    BY13 is an SRC-3 PROTAC degrader with a DC50 of 0.031 μM. It selectively obstructs the ER signaling pathway by downregulating ERα levels, showing greater selectivity over the androgen receptor (AR). BY13 effectively addresses endocrine resistance in breast cancer by inducing cell cycle arrest at the G1 phase and triggering apoptosis. Additionally, it surpasses Fulvestrant in efficacy and significantly inhibits the growth of resistant breast tumors in LCC2 xenograft mouse models, exhibiting no noticeable toxicity.
    Color and Shape:Odour Solid

    Ref: TM-T210784

    10mg
    To inquire
    50mg
    To inquire
  • Tubulin polymerization-IN-43

    CAS:
    Tubulin polymerization-IN-43 disrupts microtubules, arrests cell cycle, and induces apoptosis in leukemia by targeting colchicine sites.
    Formula:C17H13F4N3O
    Purity:99.98%
    Color and Shape:Soild
    Molecular weight:351.3

    Ref: TM-T77647

    1mg
    70.00€
    5mg
    136.00€
    10mg
    187.00€
    25mg
    309.00€
    50mg
    408.00€
    100mg
    560.00€
    200mg
    750.00€
  • Avotaciclib hydrochloride


    Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic use in specific malignancies, including
    Formula:C13H12ClN7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:317.73

    Ref: TM-T78137

    5mg
    To inquire
    50mg
    To inquire
  • Salinomycin sodium salt

    CAS:
    Salinomycin sodium salt (Sodium salinomycin), an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
    Formula:C42H69NaO11
    Purity:98.76% - 99.11%
    Color and Shape:White Or Light Yellow Crystalline Powder With Special Smel
    Molecular weight:772.98

    Ref: TM-TQ0215

    10mg
    34.00€
    1mL*10mM (DMSO)
    55.00€
  • FGFR1/VEGFR2-IN-3


    FGFR1/VEGFR2-IN-3 (Compound 8m) acts as a dual inhibitor of FGFR1 and VEGFR2. This compound exhibits both anti-cancer cell proliferation and anti-migration activities, and it also has the capability to induce cell apoptosis (apoptosis).
    Formula:C27H18N4O4
    Color and Shape:Solid
    Molecular weight:462.46

    Ref: TM-T200944

    10mg
    To inquire
    50mg
    To inquire
  • PRMT5-IN-45


    PRMT5-IN-45 (compound 36) is a potent and selective inhibitor of PRMT5, exhibiting an IC50 value of 3 nM. This compound effectively reduces the levels of symmetrical dimethylarginine (sDMA) and inhibits the proliferation of the MOLM-13 cell line by inducing apoptosis and causing cell cycle arrest.
    Formula:C26H31N7O2
    Color and Shape:Solid
    Molecular weight:473.57

    Ref: TM-T200980

    10mg
    To inquire
    50mg
    To inquire
  • PROTAC EZH2 Degrader-3


    PROTAC EZH2 Degrader-3 (compound ZJ-20) is a potent EZH2 degrader that exhibits strong inhibitory effects not only on EZH2 protein expression but also on the levels of other PRC2 subunits and H3k27me3 protein. Additionally, PROTAC EZH2 Degrader-3 demonstrates antiproliferative activity by blocking the cell cycle at the G0-G1 phase and inducing apoptosis (cell death). At a concentration of 5 μM and over a period of 24 hours, it effectively suppresses the expression of these critical proteins involved in cell regulation and growth.
    Formula:C56H68N8O8
    Color and Shape:Solid
    Molecular weight:981.19

    Ref: TM-T200955

    10mg
    To inquire
    50mg
    To inquire
  • Fludarabine triphosphate

    CAS:
    Fludarabine triphosphate inhibits key enzymes, causing cell death.
    Formula:C10H15FN5O13P3
    Color and Shape:Solid
    Molecular weight:525.17

    Ref: TM-T40862

    25mg
    1,369.00€
  • SSE1806


    SSE1806, a podophyllotoxin derivative (a natural antimitotic agent), functions as a microtubule/tubulin inhibitor, exhibiting potent anticancer and
    Formula:C21H18N2O5
    Color and Shape:Solid
    Molecular weight:378.38

    Ref: TM-T79708

    1mg
    87.00€
    5mg
    379.00€
    10mg
    648.00€
  • DH-18


    DH-18 is an inhibitor of matrix metalloproteinase-2 (MMP-2), exhibiting IC50 values of 139.45 nM for MMP-2, 518.11 nM for MMP-9, and 833.34 nM for MMP-8. The compound promotes cell apoptosis and causes cell cycle arrest in the G0/G1 phase. DH-18 also inhibits cell growth, making it potential for research in chronic myeloid leukemia.
    Formula:C26H23F6N3O5S
    Color and Shape:Solid
    Molecular weight:603.53

    Ref: TM-T200984

    10mg
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    50mg
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  • Ac-VDQQD-pNA

    CAS:
    Ac-VDQQD-pNA serves as a substrate for Caspase 2, which cleaves it to yield the yellow compound pNA (p-nitroaniline).
    Formula:C31H43N9O14
    Color and Shape:Solid
    Molecular weight:765.73

    Ref: TM-TP2849

    10mg
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    50mg
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  • Thalidomide-5-PEG2-Cl

    CAS:
    Thalidomide-5-PEG2-Cl is a cereblon ligand that recruits CRBN protein and forms PROTACs through linker conjugation.
    Formula:C17H17ClN2O6
    Color and Shape:Solid
    Molecular weight:380.78

    Ref: TM-T39721

    100mg
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    500mg
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  • PLD-IN-1


    PLD-IN-1 (Compound 3r) is an orally effective inhibitor of phospholipase D (phospholipaseD) with an IC50 of 1.97 μM. It reduces the expression of CD24, CD47, and PD-L1 while enhancing the expression of calreticulin, thereby modulating the immune evasion mechanisms of lung cancer cells by promoting the phagocytosis of cancer cells by macrophages. PLD-IN-1 inhibits the viability of lung cancer cell lines A549, HCC44, H460, and HCC15 with IC50 values of 18.44, 22.31, 24.85, and 21.45 μM, respectively. It induces apoptosis (apoptosis) in A549 cells and inhibits cell migration. Additionally, PLD-IN-1 increases pro-inflammatory M1 macrophage levels and decreases anti-inflammatory M2 macrophage levels, exhibiting anti-tumor activity in mouse models.
    Formula:C19H14F6N2O
    Color and Shape:Solid
    Molecular weight:400.32

    Ref: TM-T201135

    10mg
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    50mg
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  • Asaretoclax

    CAS:
    Asaretoclax is an effective inhibitor of B-cell lymphoma 2 (Bcl-2), demonstrating potential for use in cancer research.
    Formula:C47H57F2N7O7S
    Color and Shape:Solid
    Molecular weight:902.06

    Ref: TM-T200951

    10mg
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    50mg
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  • Annonacin

    CAS:
    Annonacin is a cytotoxic acetogenin in Graviola leaf extract; it blocks mitochondrial complex and inhibits NKA/SERCA ATPase pumps.
    Formula:C35H64O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:596.88

    Ref: TM-T14293

    1mg
    775.00€
    500µg
    421.00€
  • dFKBP-1

    CAS:
    dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].
    Formula:C53H64N6O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1009.11

    Ref: TM-T18597

    100mg
    To inquire
    500mg
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  • AMG-7209

    CAS:
    AMG-7209 is an effective and selective MDM2-p53 interaction inhibitor.
    Formula:C37H41Cl2FN2O7S
    Color and Shape:Solid
    Molecular weight:747.7

    Ref: TM-T23720

    25mg
    2,178.00€
    50mg
    2,862.00€
    100mg
    3,870.00€
  • EGFR-IN-131


    EGFR-IN-131 (compound 3a) is an efficacious EGFR inhibitor capable of crossing the blood-brain barrier, with an IC50 value of 272.9 nM. This compound exhibits anti-proliferative activity, induces cellular apoptosis (apoptosis), and causes cell cycle arrest in the G0/G1 phase. Additionally, EGFR-IN-131 reduces the protein expression of p-EGFR.
    Formula:C26H23FN4O2S
    Color and Shape:Solid
    Molecular weight:474.55

    Ref: TM-T201154

    10mg
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    50mg
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  • CDK-TCIP1

    CAS:
    CDK-TCIP1 is a bivalent molecule that links the CDK9 inhibitor SNS-032 with the BCL6 ligand BI3812. It effectively and specifically kills cells overexpressing BCL6, with an EC50 of 7.7 nM for SUDHL5 cells.
    Formula:C48H62ClN11O8S2
    Color and Shape:Solid
    Molecular weight:1020.66

    Ref: TM-T201343

    10mg
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    50mg
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  • FPR1 antagonist 1


    Compound 24a, an FPR1 antagonist, demonstrates potent inhibition of the formyl peptide receptor 1 (FPR1) with an IC50 value of 25 nM.
    Formula:C25H28O5
    Color and Shape:Solid
    Molecular weight:408.49

    Ref: TM-T79781

    5mg
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    50mg
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  • PROTAC ERα Degrader-9


    PROTACERα Degrader-9 (Compound 18c) is a dual-targeting PROTAC degrader designed to diminish estrogen receptor α (ERα) and aromatase (ARO). It demonstrates a Ki of 0.25 μM for ERα binding and an IC50 of 4.6 μM for ARO inhibition. This compound curbs proliferation in wild-type MCF-7 cells (IC50=0.54 μM) and ERα mutant variants MCF-7EGFR (IC50=0.075 μM), MCF-7D538G (IC50=0.31 μM), and MCF-7Y537S (IC50=2.3 μM), while also downregulating ERS1 and MYC expression. PROTACERα Degrader-9 arrests the cell cycle at the G2/M phase and induces apoptosis in MCF-7 cells, exhibiting antitumor efficacy in mouse models.
    Formula:C58H64F3N7O9S2
    Molecular weight:1123.4159

    Ref: TM-T210250

    10mg
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    50mg
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  • MS1943

    CAS:
    MS1943 is a orally bioavailable EZH2 selective degrader(IC50 of 120 nM).
    Formula:C42H54N8O3
    Purity:95.41% - 95.82%
    Color and Shape:Solid
    Molecular weight:718.93

    Ref: TM-T13780

    1mg
    39.00€
    2mg
    52.00€
    5mg
    84.00€
    10mg
    130.00€
    25mg
    250.00€
    50mg
    439.00€
    100mg
    802.00€
    200mg
    1,324.00€
    1mL*10mM (DMSO)
    120.00€
  • MD-265

    CAS:
    MD-265 is a PROTAC degrader that targets and degrades MDM2, leading to the activation of p53 in cancer cells with wild-type p53. MD-265 achieves complete tumor regression and enhances long-term survival in leukemic mice.
    Formula:C50H51Cl2FN6O6
    Molecular weight:921.88

    Ref: TM-T203203

    10mg
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    50mg
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  • Sarglaroids F


    Sarglaroids F (compound 6), an anti-inflammatory agent extracted from the roots of Grass Coral, suppresses LPS/ATP-induced IL-1β secretion by modulating K+
    Formula:C38H44O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:692.75

    Ref: TM-T79992

    5mg
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    50mg
    To inquire
  • TS-24

    CAS:

    TS-24 is a cysteine protease histone S (CTSS) inhibitor that promotes BRCA1-mediated apoptosis.

    Formula:C20H15NO2
    Purity:99.41%
    Color and Shape:Soild
    Molecular weight:301.34

    Ref: TM-T85311

    1mg
    69.00€
    5mg
    149.00€
    10mg
    230.00€
    25mg
    464.00€
    50mg
    747.00€
    100mg
    1,198.00€
  • 15-Acetoxyscirpenol

    CAS:
    15-acetoxyscirpenol: ASM that induces apoptosis, inhibits Jurkat T cell growth dose-dependently, and activates caspases other than caspase-3.
    Formula:C17H24O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:324.373

    Ref: TM-T14003

    5mg
    2,170.00€
  • Cefatrizine

    CAS:
    Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.
    Formula:C18H18N6O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.5

    Ref: TM-T26973

    25mg
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    50mg
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    100mg
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  • Tomatine hydrochloride

    CAS:
    Tomatine hydrochloride halts fungi/bacteria growth, is extracted from wild tomato leaves, and precipitates steroids.
    Formula:C50H84ClNO21
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1070.65

    Ref: TM-T3786L

    25mg
    1,369.00€
  • Sec61-IN-4


    Sec61-IN-4 (Compound 16b) is a potent Sec61 inhibitor with an IC50 value of 0.04 nM in U87-MG cells [1].
    Color and Shape:Odour Solid

    Ref: TM-T81184

    5mg
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    50mg
    To inquire
  • Ferroptosis-IN-12


    Ferroptosis-IN-12 (Cpd-A1) is an inhibitor of ferroptosis. It effectively suppresses ferroptosis in mouse renal tubular epithelial cells (mTECs) treated with Erastin and improves renal function in dose-dependent manners in mouse models of acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP). This compound also reduces renal tubular damage and eliminates inflammation. Exhibiting good plasma stability and high distribution in renal tissues during pharmacokinetic studies in mice, Ferroptosis-IN-12 shows promising potential for research in the field of AKI.
    Color and Shape:Odour Solid

    Ref: TM-T200665

    10mg
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    50mg
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  • Diprovocim-1

    CAS:
    Diprovocim-1: TLR1/2 agonist; triggers TNF-α in THP-1 cells; boosts ovalbumin IgG1 & CTLs against tumors with anti-PD-L1 in mice.
    Formula:C56H56N6O6
    Color and Shape:Solid
    Molecular weight:909.1

    Ref: TM-T37722

    1mg
    239.00€
    5mg
    593.00€
    10mg
    1,018.00€
  • Thiocolchicine

    CAS:
    Thiocolchicine inhibits tubulin polymerization (IC50: 2.5 µM, Ki: 0.7 µM), induces apoptosis, and serves as an ADC cytotoxin.
    Formula:C22H25NO5S
    Purity:98.19%
    Color and Shape:Solid
    Molecular weight:415.5

    Ref: TM-T41248

    5mg
    46.00€
    10mg
    66.00€
    25mg
    120.00€
    50mg
    192.00€
    100mg
    308.00€
    1mL*10mM (DMSO)
    55.00€
  • Enniatin A1

    CAS:
    Enniatin A1, a cyclic hexadepsipeptide from Fusarium, induces apoptosis and disrupts ERK, inhibiting ACAT (IC50: 49 μM).
    Formula:C35H61N3O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:667.885

    Ref: TM-T11201

    1mg
    647.00€
  • PROTAC FLT-3 degrader 1

    CAS:
    PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.
    Formula:C52H61N9O9S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1020.23

    Ref: TM-T12555

    100mg
    To inquire
    500mg
    To inquire
  • Bcl-2-IN-4

    CAS:
    Bcl-2-IN-4: potent, selective, oral Bcl-2 inhibitor with 1.5 nM IC50, >200x selectivity over Bcl-xL.
    Formula:C46H50ClN9O7S
    Color and Shape:Solid
    Molecular weight:908.46

    Ref: TM-T74297

    5mg
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    50mg
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  • ABBV-167

    CAS:
    ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.
    Formula:C46H53ClN7O11PS
    Color and Shape:Solid
    Molecular weight:978.45

    Ref: TM-T38750

    5mg
    299.00€
  • Pexelizumab

    CAS:
    Pexelizumab is a humanized antibody targeting C5 to inhibit apoptosis and treat cerebral IR injury and myocardial infarction.
    Color and Shape:Liquid

    Ref: TM-T77163

    5mg
    To inquire
  • Oligomycin B

    CAS:
    Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis.
    Formula:C45H72O12
    Purity:98%
    Color and Shape:Solid
    Molecular weight:805.05

    Ref: TM-T12298

    1mg
    92.00€
    5mg
    310.00€
    10mg
    487.00€
  • KRAS inhibitor-40

    CAS:
    KRAS inhibitor-40 (Compound 41) is an inhibitor of KRAS, disrupting the KRAS G12C-BRAF complex and suppressing the phosphorylation of the downstream ERK signaling pathway. This compound also inhibits the proliferation of tumor cells with various KRAS mutations, exhibiting antitumor activity.
    Formula:C53H66ClF4N9O8S
    Color and Shape:Solid
    Molecular weight:1100.66

    Ref: TM-T204518

    10mg
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    50mg
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  • PARP1-IN-17


    PARP1-IN-17 is an inhibitor that targets PARP-1 (IC50=19.24 nM ) with a slightly reduced affinity for PARP-2 (IC50=32.58 nM ) and induces apoptosis.
    Purity:98%
    Color and Shape:Odour Solid

    Ref: TM-T81543

    5mg
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    50mg
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  • CDD-2807


    CDD-2807 is a serine/threonine kinase 33 (STK33) inhibitor with an IC50 of 9.2 nM. In mice, CDD-2807 demonstrates no significant toxicity and can cross the blood-testis barrier without accumulating in the brain. It offers reversible contraceptive effects, indicating potential for development as a male contraceptive.
    Formula:C29H26N4O
    Molecular weight:446.21066

    Ref: TM-T210217

    10mg
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    50mg
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  • AS-99 free base

    CAS:
    AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity.
    Formula:C27H30F3N5O3S2
    Color and Shape:Solid
    Molecular weight:593.68

    Ref: TM-T36977

    5mg
    785.00€
  • Suc-Ala-Leu-Pro-Phe-pNA

    CAS:
    Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA), a substrate for FK-506 binding protein (FKBP) [1], showcases the intricate interactions necessary for specific
    Formula:C33H42N6O9
    Color and Shape:Solid
    Molecular weight:666.72

    Ref: TM-T76622

    5mg
    To inquire
    50mg
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  • Diethyl phthalate

    CAS:
    Diethyl phthalate disrupts endocrine and induces apoptosis in PC12 cells; common in plastics, personal care items.
    Formula:C12H14O4
    Purity:99.68% - 99.8%
    Color and Shape:Solid
    Molecular weight:222.24

    Ref: TM-TN6982

    10g
    33.00€
    1mL*10mM (DMSO)
    34.00€
  • MDM2/4-p53-IN-3


    MDM2/4-p53-IN-3 inhibits MDM2/4-p53 PPIs (IC50: 18.5nM MDM2, 14.8nM MDM4), used in cancer research.
    Formula:C25H24Cl2FN3O3
    Color and Shape:Solid
    Molecular weight:504.38

    Ref: TM-T74936

    5mg
    To inquire
    50mg
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  • PDE4D inhibitor 1


    PDE4-IN-1 is a PDE4 inhibitor characterized by high potency (IC50: 8.6 nM) and superior selectivity over other PDE subtypes. This compound inhibits the release of inflammatory cytokines and chemokines. Additionally, PDE4-IN-1 significantly restores the damaged cAMP-CREB signaling pathway, inhibits proliferation, and promotes differentiation to reverse psoriasis formation.
    Color and Shape:Odour Solid

    Ref: TM-T206858

    10mg
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    50mg
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  • ARV-393 HCl


    ARV-393 HCl is an orally active and potent PROTAC targeting BCL6 with antitumor activity for the study of non-Hodgkin's lymphoma.
    Formula:C46H54Cl2FN9O7
    Purity:99.79%
    Color and Shape:Solid
    Molecular weight:934.88

    Ref: TM-T84316L

    1mg
    220.00€
    5mg
    539.00€
    10mg
    855.00€
    25mg
    1,690.00€
    50mg
    2,675.00€
  • (R)-MIK665

    CAS:
    (R)-MIK665 is the less active enantiomer of MIK665. MIK665 is a special inhibitor of Mcl-1(IC50 of 1.81 nM).
    Formula:C47H44ClFN6O6S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:875.41

    Ref: TM-T12629

    25mg
    9,565.00€
  • RIPK1-IN-17

    CAS:
    RIPK1-IN-17 is a dual inhibitor of RIPK1 and RIPK3 inhibits necrosis by inhibiting phosphorylation of RIPK1, RIPK3 and MLKL,in a tnf-induced inflammation model.
    Formula:C26H19F4N3O3S
    Purity:95.22%
    Color and Shape:Solid
    Molecular weight:529.51

    Ref: TM-T81268

    1mg
    50.00€
    5mg
    99.00€
    10mg
    152.00€
    25mg
    250.00€
    50mg
    369.00€
  • Anticancer agent 205


    Anticanceragent 205 (compound 9) is an effective anticancer agent that binds to the G4-mtDNA target, inhibiting the replication, transcription, and translation of mtDNA (mitochondrial genome). It induces mitochondrial dysfunction, increases ROS production, and triggers DNA damage and cellular senescence. Anticanceragent 205 also promotes apoptosis and causes cell cycle arrest at the G0/G1 phase, showing potential for research in colorectal cancer.
    Formula:C52H60I2N4
    Molecular weight:994.29074

    Ref: TM-T209798

    10mg
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    50mg
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