Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5598 products of "Apoptosis"
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Topoisomerase IIα-IN-3
CAS:<p>Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.</p>Formula:C29H20N6O2SColor and Shape:SolidMolecular weight:516.57HL271
CAS:<p>HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.</p>Formula:C13H17ClF3N5OPurity:98%Color and Shape:SolidMolecular weight:351.76Anti-inflammatory agent 54
CAS:<p>Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression</p>Formula:C17H16N2O5Color and Shape:SolidMolecular weight:328.32Thienopyridone
CAS:<p>Thienopyridone: potent, selective PRL phosphatase inhibitor, IC50s: 173/277/128 nM for PRL-1/2/3, induces apoptosis, anticancer.</p>Formula:C13H10N2OSPurity:98%Color and Shape:SolidMolecular weight:242.3RSH-7
CAS:<p>RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing</p>Formula:C22H25FN8OPurity:98.31%Color and Shape:SolidMolecular weight:436.49HDAC-IN-36
CAS:<p>HDAC-IN-36: Oral HDAC6 inhibitor, IC50 = 11.68 nM, promotes apoptosis & autophagy, anti-tumor & anti-metastatic, for breast cancer research.</p>Formula:C29H39N5O5Color and Shape:SolidMolecular weight:537.65RET-IN-22
CAS:<p>RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-</p>Formula:C29H31F3N6O4Color and Shape:SolidMolecular weight:584.59Topoisomerase I inhibitor 5
CAS:<p>Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.</p>Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46Antitumor agent-62
CAS:<p>Antitumor agent-62 releases NO, inhibits cancer cell growth, triggers apoptosis, and halts cell cycle at G2/M.</p>Formula:C21H19N3O9SColor and Shape:SolidMolecular weight:489.46IMM-H004
CAS:<p>IMM-H004 is an effective inhibitor of BV2 microglia activation.</p>Formula:C16H20N2O4Purity:98%Color and Shape:SolidMolecular weight:304.34Methylisothiazolinone
CAS:<p>Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.</p>Formula:C4H5NOSPurity:99.78%Color and Shape:Colorless Prisms LiquidMolecular weight:115.15BTK-IN-24
CAS:<p>BTK-IN-24 is a Bruton's tyrosine kinase (BTK) inhibitor with potential anticancer activity, and it can be used in the study of myeloproliferative disorders.</p>Formula:C26H19F4N5O2Purity:99.61%Color and Shape:SolidMolecular weight:509.46Nampt-IN-3
CAS:<p>Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).</p>Formula:C29H25N7O2Purity:98%Color and Shape:SolidMolecular weight:503.55CCT373567
CAS:<p>CCT373567 is a potent degrader of the transcriptional repressor BCL6 (IC50: 2.9 nM) and exhibits anti-proliferative effects.</p>Formula:C26H29ClF2N6O3Color and Shape:SolidMolecular weight:547KY1022
CAS:<p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>Formula:C17H19N3OSColor and Shape:SolidMolecular weight:313.42CEP-40125
CAS:<p>CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.</p>Formula:C28H45Cl2N3O2Purity:98.28%Color and Shape:SolidMolecular weight:526.58TH1834 dihydrochloride
CAS:<p>TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.</p>Formula:C33H42Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:641.63Topoisomerase II inhibitor 3
CAS:<p>Acridone-based Topoisomerase II inhibitor 3 targets topo IIα/β (IC50: 0.17μM α, 0.23μM β), causes DNA damage, and induces apoptosis.</p>Formula:C18H20N4O4Color and Shape:SolidMolecular weight:356.38Tezacitabine
CAS:<p>Tezacitabine, a nucleoside analogue, inhibits ribonucleotide reductase, disrupts DNA replication, and induces apoptosis in tumor cells.</p>Formula:C10H12FN3O4Color and Shape:SolidMolecular weight:257.22Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Formula:C32H36N10O2Purity:98%Color and Shape:SolidMolecular weight:592.69Perillic acid
CAS:<p>Perillic acid, a perillyl alcohol metabolite, induces lung cancer cell arrest, apoptosis, and has anti-HSV-1 and immune-modulating effects.</p>Formula:C10H14O2Color and Shape:SolidMolecular weight:166.22PDE5/HDAC-IN-1
CAS:<p>PDE5/HDAC-IN-1 is a potent inhibitor of phosphodiesterase 5 (PDE5) and HDAC, with IC50 values of 46.3 nM and 14.5 nM, respectively.</p>Formula:C27H29BrN4O4Color and Shape:SolidMolecular weight:553.45MSN-125
CAS:<p>MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.</p>Formula:C36H38BrN3O6Purity:98%Color and Shape:SolidMolecular weight:688.61Antitumor agent-44
CAS:<p>Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in human</p>Formula:C24H15N3O3Color and Shape:SolidMolecular weight:393.39BR102375
CAS:<p>BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.</p>Formula:C31H34N6O4Purity:98%Color and Shape:SolidMolecular weight:554.64Flonoltinib
CAS:<p>Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.</p>Formula:C25H34FN7OPurity:99.52%Color and Shape:SolidMolecular weight:467.58NKP-1339
CAS:<p>NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.</p>Formula:C14H12Cl4N4NaRuPurity:98%Color and Shape:SolidMolecular weight:502.14Anticancer agent 32
CAS:<p>Compound 2g, an anticancer agent, disrupts cell cycle and induces apoptosis for cancer research.</p>Formula:C24H21F2N5OColor and Shape:SolidMolecular weight:433.45AKCI
CAS:<p>AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.</p>Formula:C19H27N7OPurity:98%Color and Shape:SolidMolecular weight:369.46RETRA
CAS:<p>RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.</p>Formula:C11H12BrNO3S2Purity:98%Color and Shape:SolidMolecular weight:350.25SB 706504
CAS:<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formula:C24H19F3N8OPurity:98.686%Color and Shape:SolidMolecular weight:492.46SHP2-IN-8
CAS:<p>SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.</p>Formula:C17H21Cl2N5SColor and Shape:SolidMolecular weight:398.35N1,N11-Diethylnorspermine
CAS:<p>DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.</p>Formula:C13H32N4Color and Shape:SolidMolecular weight:244.42CK2/ERK8-IN-1
CAS:<p>TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.</p>Formula:C11H9Br4N3O2Purity:98.22%Color and Shape:SolidMolecular weight:534.82BMS-200
CAS:BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.Formula:C27H27F2NO6Color and Shape:SolidMolecular weight:499.5Nimustine
CAS:<p>Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.</p>Formula:C9H13ClN6O2Color and Shape:SolidMolecular weight:272.69Antitumor agent-70
CAS:<p>Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.</p>Formula:C21H18N4O2Color and Shape:SolidMolecular weight:358.39PI3K/AKT-IN-2
CAS:<p>PI3K/AKT-IN-2 inhibits PI3K/AKT, EMT, induces apoptosis, and blocks tubulin polymerization.</p>Formula:C32H27BrO10Color and Shape:SolidMolecular weight:651.45Merck-22-6
CAS:<p>Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.</p>Formula:C40H43N7O2Color and Shape:SolidMolecular weight:653.82DC-CPin711
CAS:<p>DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.</p>Formula:C23H22N4O2Color and Shape:SolidMolecular weight:386.45Semapimod
CAS:<p>Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.</p>Formula:C34H52N18O2Color and Shape:SolidMolecular weight:744.9BPTQ
CAS:<p>BPTQ: DNA intercalator, halts cancer cell growth by blocking S/G2/M phases.</p>Formula:C17H16N4SPurity:98%Color and Shape:SolidMolecular weight:308.4Mcl1-IN-4
CAS:Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formula:C28H26N2O5SPurity:98%Color and Shape:SolidMolecular weight:502.58VEGFR-2-IN-19
CAS:<p>VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.</p>Formula:C21H19N3O2Color and Shape:SolidMolecular weight:345.39MG-115
CAS:<p>MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.</p>Formula:C25H39N3O5Purity:97.12%Color and Shape:White PowderMolecular weight:461.59CRA-026440
CAS:<p>CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7</p>Formula:C23H24N4O4Purity:96.42%Color and Shape:SolidMolecular weight:420.46RET-IN-6
CAS:<p>RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).</p>Formula:C30H29N7Color and Shape:SolidMolecular weight:487.6Tubulin polymerization-IN-24
CAS:<p>HMBA (Tubulin-IN-24) inhibits tubulin assembly, boosts GTP hydrolysis, induces apoptosis, and arrests G2/M phase in MCF-7 cells.</p>Formula:C22H16O3Color and Shape:SolidMolecular weight:328.36IHMT-TRK-284
CAS:<p>IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.</p>Formula:C25H27N7OSColor and Shape:SolidMolecular weight:473.59Metoprolol fumarate
CAS:<p>Metoprolol fumarate (CGP 2175C): selective β1-blocker with anti-inflammatory, antitumor, anti-angiogenic effects.</p>Formula:C34H54N2O10Color and Shape:SolidMolecular weight:650.8Shield-2
CAS:<p>Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.</p>Formula:C35H51N3O7Purity:98%Color and Shape:SolidMolecular weight:625.8Epirubicin
CAS:<p>Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.</p>Formula:C27H29NO11Color and Shape:SolidMolecular weight:543.52AG-024322
CAS:<p>AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.</p>Formula:C23H20F2N6Purity:98.53%Color and Shape:SolidMolecular weight:418.44ZDLD13
CAS:<p>ZDLD13, a β-carboline, inhibits CDK4/CycD3, halts HCT116 tumor growth, and induces apoptosis with IC50=0.38μM.</p>Formula:C18H14N4OColor and Shape:SolidMolecular weight:302.33MSN-50
CAS:<p>MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.</p>Formula:C36H38BrN3O6Color and Shape:SolidMolecular weight:688.61Mcl1-IN-11
CAS:<p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>Formula:C38H41N3O5S2Purity:98%Color and Shape:SolidMolecular weight:683.88PD180970
CAS:<p>PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.</p>Formula:C21H15Cl2FN4OPurity:98.67%Color and Shape:SolidMolecular weight:429.27Verrucarin J
CAS:<p>Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).</p>Formula:C27H32O8Color and Shape:SolidMolecular weight:484.54Prexasertib mesylate
CAS:<p>Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.</p>Formula:C19H23N7O5SPurity:98%Color and Shape:SolidMolecular weight:461.49ABT-100
CAS:<p>ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.</p>Formula:C27H19F3N4O3Purity:98%Color and Shape:SolidMolecular weight:504.46BJE6-106
CAS:<p>BJE6-106 (B106) is a potent, selective PKCδ inhibitor (IC50: 0.05 μM) and targets selectivity over classical PKCα (IC50: 50 μM).</p>Formula:C26H23NO2Color and Shape:SolidMolecular weight:381.47CSRM617
CAS:<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Formula:C10H13N3O5Purity:98%Color and Shape:SolidMolecular weight:255.23hCAIX-IN-12
CAS:<p>hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.</p>Formula:C18H14N4O3S2Color and Shape:SolidMolecular weight:398.46VRT-043198
CAS:<p>VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.</p>Formula:C22H29ClN4O6Color and Shape:SolidMolecular weight:480.94NSC745885
CAS:<p>NSC745885 decreases EZH2, has selective cancer cell toxicity, and is studied for bladder and OSCC.</p>Formula:C14H6N2O2SPurity:98%Color and Shape:SolidMolecular weight:266.27bpV(phen)
CAS:<p>bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).</p>Formula:C12H8KN2O5VPurity:98%Color and Shape:SolidMolecular weight:350.24CDK1/Cyc B-IN-1
CAS:<p>CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.</p>Formula:C14H12ClN3O2S2Color and Shape:SolidMolecular weight:353.85SDZ 224-015
CAS:<p>SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.</p>Formula:C30H35Cl2N3O9Purity:95.49% - 95.49%Color and Shape:SolidMolecular weight:652.52DRI-C25441
CAS:<p>DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered</p>Formula:C31H21N3O6Color and Shape:SolidMolecular weight:531.51SLMP53-2
CAS:<p>SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with</p>Formula:C26H22N2O2Color and Shape:SolidMolecular weight:394.47Epofolate
CAS:<p>Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.</p>Formula:C67H92N16O22S3Color and Shape:SolidMolecular weight:1569.74Flunisolide hemihydrate
CAS:<p>Flunisolide hemihydrate, a corticosteroid with anti-inflammatory properties, treats asthma and rhinitis by inducing eosinophil apoptosis.</p>Formula:C48H64F2O13Color and Shape:SolidMolecular weight:887.024PI3Kα-IN-6
CAS:<p>PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.</p>Formula:C16H15IN2OSColor and Shape:SolidMolecular weight:410.27S65487
CAS:<p>S65487 (VOB560) inhibits Bcl-2, including G101V and D103Y variants, while sparing MCL-1, BFL-1, and BCL-XL, supporting its anticancer potential.</p>Formula:C41H41ClN6O4Purity:99.034%Color and Shape:SolidMolecular weight:717.26Casein Kinase inhibitor A51
CAS:<p>Casein Kinase inhibitor A51 is a CK1α inhibitor with anticancer activity used in the study of breast and prostate cancer.</p>Formula:C18H25ClN6Purity:99.88%Color and Shape:SolidMolecular weight:360.88Prinomastat hydrochloride
CAS:<p>Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.</p>Formula:C18H22ClN3O5S2Purity:98%Color and Shape:SolidMolecular weight:459.97Anisperimus
CAS:<p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55Topoisomerase I inhibitor 2
CAS:<p>ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.</p>Formula:C18H15NO3Color and Shape:SolidMolecular weight:293.32Sparfosic acid trisodium
CAS:<p>Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumour</p>Formula:C6H9NNaO8PPurity:98%Color and Shape:SolidMolecular weight:277.1ARN5187
CAS:<p>ARN5187, a lysosomal REV-ERB β ligand, inhibits transcription and autophagy, shows efficacy, cytotoxicity, and induces apoptosis.</p>Formula:C24H32FN3OColor and Shape:SolidMolecular weight:397.53PHA-690509
CAS:<p>PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.</p>Formula:C17H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:331.43PDE4-IN-10
CAS:<p>PDE4-IN-10 (7a), potent PDE4B inhibitor, IC50 7.01μM; selective, stable, TNF-α blocking, non-toxic in vitro.</p>Formula:C18H13NColor and Shape:SolidMolecular weight:243.3Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formula:C29H38FN3O5Purity:97.07% - 98.07%Color and Shape:SolidMolecular weight:527.63Quinate
CAS:<p>Quinate: oral antiarrhythmic, inhibits P450db, blocks K+ channels (IC50 19.9 μM), used in malaria research.</p>Formula:C26H36N2O9Color and Shape:SolidMolecular weight:520.579CAY10506
CAS:<p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>Formula:C20H26N2O4S3Color and Shape:SolidMolecular weight:454.63PhiKan 083 hydrochloride
CAS:<p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>Formula:C16H19ClN2Purity:98%Color and Shape:SolidMolecular weight:274.79Telomerase-IN-5
CAS:<p>Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].</p>Formula:C22H20N4OS2Purity:98%Color and Shape:SolidMolecular weight:420.55673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27QM31
CAS:<p>QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).</p>Formula:C39H38Cl4N4O4Purity:98%Color and Shape:SolidMolecular weight:768.56Antiproliferative agent-32
CAS:<p>Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cells</p>Formula:C19H15NO2Purity:98%Color and Shape:SolidMolecular weight:289.33MPT0B392
CAS:<p>MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.</p>Formula:C19H20N2O6SColor and Shape:SolidMolecular weight:404.442,5-Dihydroxybiphenyl
CAS:<p>2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.</p>Formula:C12H10O2Purity:99.66%Color and Shape:White To Grey-Brownish PowderMolecular weight:186.21Atopaxar Hydrobromide
CAS:<p>Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formula:C29H39BrFN3O5Purity:98%Color and Shape:SolidMolecular weight:608.54EGFR-IN-59
CAS:<p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>Formula:C27H23N5O4SColor and Shape:SolidMolecular weight:513.57Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Formula:C32H40BrN3O2Purity:98%Color and Shape:SolidMolecular weight:578.58FW1256
CAS:<p>FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.</p>Formula:C12H10NOPSColor and Shape:SolidMolecular weight:247.25ML132
CAS:<p>ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).</p>Formula:C22H28ClN5O5Color and Shape:SolidMolecular weight:477.94VII-31
CAS:<p>VII-31 is an activator of the NEDDylation pathway, capable of inducing apoptosis in MCF-7, PC-3, and MGC-803 cells.</p>Formula:C23H25NO5SColor and Shape:SolidMolecular weight:427.51APPA
CAS:<p>APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of</p>Formula:C14H13NO3Purity:98%Color and Shape:SolidMolecular weight:243.26RET-IN-8
CAS:<p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Formula:C27H30N6O3Color and Shape:SolidMolecular weight:486.57
