Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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3-(3-Phenoxybenzyl)amino-β-carboline
CAS:3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.Formula:C24H19N3OColor and Shape:SolidMolecular weight:365.43Sibiriline
CAS:Sibiriline is a Receptor-Interacting Protein Kinase 1 inhibitor that acts by preventing immune-dependent hepatitis.Formula:C13H10N2OPurity:98%Color and Shape:SolidMolecular weight:210.23RS6212
CAS:RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.Formula:C20H22N4O3SColor and Shape:SolidMolecular weight:398.48RIP1 kinase inhibitor 7
CAS:RIP1 Kinase Inhibitor 7 (Compound 41) serves as a potent inhibitory agent for receptor interacting protein 1 kinase (RIP1) with an IC50 of under 100 nM.Formula:C20H20FN3OPurity:98%Color and Shape:SolidMolecular weight:337.39PhiKan 083 hydrochloride
CAS:PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).Formula:C16H19ClN2Purity:98%Color and Shape:SolidMolecular weight:274.79CK2/ERK8-IN-1
CAS:TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.Formula:C11H9Br4N3O2Purity:98.22%Color and Shape:SolidMolecular weight:534.82TNF-α-IN-18
CAS:TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.Formula:C16H7ClF2O4Purity:99.77%Color and Shape:SolidMolecular weight:336.67Norartocarpetin
CAS:Norartocarpetin inhibits tyrosinase (IC50 0.47μM), prevents browning in food, and fights lung cancer (IC50 22μM) by disrupting cell mechanisms.Formula:C15H10O6Color and Shape:SolidMolecular weight:286.24FL3
CAS:FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.Formula:C25H23BrO5Color and Shape:SolidMolecular weight:483.35ASK1-IN-3
CAS:ASK1-IN-3, selective ASK1 inhibitor with 33.8 nM IC50; inhibits cell cycle kinases; induces apoptosis in HepG2 cells.Formula:C18H18N8O2Color and Shape:SolidMolecular weight:378.39MDM2-IN-1
CAS:MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.Formula:C23H21Cl2FN2O3Color and Shape:SolidMolecular weight:463.33YH-306
CAS:YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.Formula:C19H18N2O2Purity:98.06%Color and Shape:SolidMolecular weight:306.36HMBPP triammonium
CAS:HMBPP triammonium is a stimulator of gamma delta T cells.Formula:C5H15NO8P2Color and Shape:SolidMolecular weight:279.122TL02-59 dihydrochloride
CAS:TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).Formula:C32H36Cl2F3N5O4Purity:98%Color and Shape:SolidMolecular weight:682.562,3-DCPE
CAS:Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).Formula:C11H15Cl2NO2Purity:98%Color and Shape:SolidMolecular weight:264.15UCD38B HCl
CAS:UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.Formula:C15H17Cl2N7O3Purity:98%Color and Shape:SolidMolecular weight:414.25Anti-melanoma agent 1
CAS:Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.Formula:C28H28N2O2Color and Shape:SolidMolecular weight:424.53HBV-IN-23
CAS:HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.Formula:C25H27N3O3SColor and Shape:SolidMolecular weight:449.57Nec-3a
CAS:Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.Formula:C21H18F4N2O4Color and Shape:SolidMolecular weight:438.37DAT-230
CAS:DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.Formula:C20H21NO2SColor and Shape:SolidMolecular weight:339.45Topoisomerase I inhibitor 3
CAS:Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.Formula:C18H14FNO3Color and Shape:SolidMolecular weight:311.31PI3Kδ-IN-10
CAS:PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).Formula:C19H16ClN9Color and Shape:SolidMolecular weight:405.84Caspase-9 Inhibitor III
CAS:Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.Formula:C24H35ClN6O9Color and Shape:SolidMolecular weight:587.02HLI 373
CAS:HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.Formula:C18H23N5O2Color and Shape:SolidMolecular weight:341.41Autophagy-IN-2
CAS:Autophagy-IN-2 (7h) blocks autophagic flux, triggers cancer cell death, aids in triple-negative breast cancer study.Formula:C17H19N5OColor and Shape:SolidMolecular weight:309.37RGB-286147
CAS:RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.Formula:C23H22Cl2N4O3Purity:98%Color and Shape:SolidMolecular weight:473.35(R)-eIF4A3-IN-2
CAS:(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.Formula:C25H19Br2ClN4O2Color and Shape:SolidMolecular weight:602.71Caspase-3/7 activator 3
Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.Formula:C24H27NO5Color and Shape:SolidMolecular weight:409.47Anticancer agent 63
CAS:Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.Formula:C17H24F3NOSeColor and Shape:SolidMolecular weight:394.33PSB 0474
CAS:P2Y6 receptor agonistFormula:C17H20N2O13P2Purity:98%Color and Shape:SolidMolecular weight:522.29Bisindolylmaleimide VIII
CAS:Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.
Formula:C24H22N4O2Purity:97% - 98.01%Color and Shape:SolidMolecular weight:398.46PK9327
CAS:PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.Formula:C21H22N2SColor and Shape:SolidMolecular weight:334.48PI3Kα-IN-6
CAS:PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.Formula:C16H15IN2OSColor and Shape:SolidMolecular weight:410.27GW-3333
CAS:GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.Formula:C22H36N4O4Purity:98%Color and Shape:SolidMolecular weight:420.55BRD0476
CAS:BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.Formula:C35H38N4O8SPurity:98%Color and Shape:SolidMolecular weight:674.76TPB15
CAS:TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.Formula:C18H9Cl4N5OColor and Shape:SolidMolecular weight:453.11CDK6/PIM1-IN-1
CAS:CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.Formula:C25H28FN9Color and Shape:SolidMolecular weight:473.55Luxeptinib
CAS:Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.Formula:C25H17F4N5O2Color and Shape:SolidMolecular weight:495.43MRS 2693 trisodium salt
CAS:MRS 2693 trisodium salt is a P2Y6 agonist.Formula:C9H22IN5O12P2Purity:98%Color and Shape:SolidMolecular weight:581.15hnRNPK-IN-1
CAS:hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43PI3K-IN-34
CAS:PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.Formula:C23H22N6O3Color and Shape:SolidMolecular weight:430.46PI3Kδ/γ-IN-3
CAS:PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).Formula:C23H20ClN9OColor and Shape:SolidMolecular weight:473.92SZM-1209
CAS:SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.Formula:C31H29F5N4O5S2Purity:98%Color and Shape:SolidMolecular weight:696.71DRAK1/2-IN-1
CAS:DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.Formula:C22H24N2O3SColor and Shape:SolidMolecular weight:396.5ISC-4
CAS:ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.Formula:C11H13NSeColor and Shape:SolidMolecular weight:238.19BS-181
CAS:BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.Formula:C22H32N6Purity:98%Color and Shape:SolidMolecular weight:380.53RIPK1-IN-11
CAS:RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Formula:C23H24N4O4SColor and Shape:SolidMolecular weight:452.53Antitumor agent-56
CAS:Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.Formula:C28H28N2O10SColor and Shape:SolidMolecular weight:584.59Aurora A inhibitor 2
CAS:Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).Formula:C24H26N6O3Color and Shape:SolidMolecular weight:446.5Mammea A/BA
CAS:Mammea A/BA combats T. cruzi by causing mitochondrial damage, ROS, DNA fragmentation, and vacuolization, leading to cell death. Useful for Chagas research.Formula:C25H26O5Color and Shape:SolidMolecular weight:406.47Tubulin polymerization-IN-17
CAS:Compound 23g, a potent inhibitor of tubulin aggregation, induces apoptosis, and inhibits cell migration; promising for cancer research.Formula:C26H23NO5Color and Shape:SolidMolecular weight:429.46Ludartin
CAS:Ludartin activates TRPA1, induces DNA damage, and lowers mitochondrial potential, yielding anticancer effects.Formula:C15H18O3Color and Shape:SolidMolecular weight:246.3EGFR-IN-57
CAS:EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.Formula:C22H15N3O2SColor and Shape:SolidMolecular weight:385.44Metaproterenol
CAS:Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).Formula:C11H17NO3Purity:98%Color and Shape:SolidMolecular weight:211.26AG311
CAS:AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.
Formula:C17H15N5SColor and Shape:SolidMolecular weight:321.4PI3K-IN-33
CAS:PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.Formula:C23H21BrN6O2Color and Shape:SolidMolecular weight:493.36PI3Kδ-IN-11
CAS:PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.Formula:C27H21N5OColor and Shape:SolidMolecular weight:431.49Bcl-2/Mcl-1-IN-3
CAS:Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.Formula:C27H26ClNO4Color and Shape:SolidMolecular weight:463.95GGTI-2154
CAS:GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity againstFormula:C24H28N4O3Color and Shape:SolidMolecular weight:420.5VO-OHPic
CAS:VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.Formula:C12H10N2O8VColor and Shape:SolidMolecular weight:361.16Anti-inflammatory agent 22
CAS:Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.Formula:C22H16O6Color and Shape:SolidMolecular weight:376.36IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formula:C21H28N4O2Color and Shape:SolidMolecular weight:368.47NSC114792
CAS:NSC114792 is a selective JAK3 inhibitor.Formula:C26H32N4O2SPurity:98%Color and Shape:SolidMolecular weight:464.62Antiproliferative agent-7
CAS:Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.Formula:C28H32N4OColor and Shape:SolidMolecular weight:440.58S-Gem
CAS:S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.Formula:C13H15F2N3O6S2Purity:98%Color and Shape:SolidMolecular weight:411.4DMH2
CAS:DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.Formula:C27H25N5O2Purity:98%Color and Shape:SolidMolecular weight:451.52EGFR-IN-60
CAS:EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.Formula:C28H28Cl2N6OColor and Shape:SolidMolecular weight:535.47Antioxidant agent-5
CAS:Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.Formula:C24H24N6OColor and Shape:SolidMolecular weight:412.49LLP-3
CAS:Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.Formula:C32H23ClN2O4Color and Shape:SolidMolecular weight:534.99c-Met-IN-14
CAS:c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.Formula:C34H38ClFN4O7SColor and Shape:SolidMolecular weight:701.2Anticancer agent 83
CAS:Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.Formula:C20H19N5OSColor and Shape:SolidMolecular weight:377.46Cadein1
Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.Formula:C33H48F2INO2Color and Shape:SolidMolecular weight:655.64BMS-37
CAS:BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.Formula:C27H32N2O4Color and Shape:SolidMolecular weight:448.55GEM144
CAS:GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.Formula:C28H31NO5Color and Shape:SolidMolecular weight:461.55ATSP-7041
CAS:ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)Formula:C87H125N17O21Color and Shape:SolidMolecular weight:1745.02Se-Methylselenocysteine hydrochloride
CAS:Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.Formula:C4H10ClNO2SePurity:98%Color and Shape:SolidMolecular weight:218.54(S)-PERK-IN-5
CAS:(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).Formula:C25H26F2N4O3Color and Shape:SolidMolecular weight:468.5p53 Activator 2
CAS:p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.Formula:C20H21N5O2Color and Shape:SolidMolecular weight:363.41TrxR inhibitor D9
CAS:TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).Formula:C25H20AuOPSColor and Shape:SolidMolecular weight:596.43YLT205
CAS:YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.Formula:C16H12BrClN4O2S2Purity:98%Color and Shape:SolidMolecular weight:471.78AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Formula:C25H20N4O2Purity:98%Color and Shape:SolidMolecular weight:408.45Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Formula:C25H21ClN2O5Color and Shape:SolidMolecular weight:464.9LG308
CAS:LG308, a synthetic compound, has anti-tumor properties, inducing apoptosis and mitotic arrest, thereby suppressing prostate cancer growth.Formula:C19H17FN2OColor and Shape:SolidMolecular weight:308.35PHA-680626
CAS:PHA-680626 is a PLK inhibitor, effective on resistant leukemia cells, with IC50: Plk1 (0.53 μM), Plk2 (0.07 μM), Plk3 (1.61 μM).Formula:C23H26N6O2SColor and Shape:SolidMolecular weight:450.56Anti-inflammatory agent 47
CAS:Flo8, an anti-inflammatory and antioxidant agent, effectively suppresses the release of reactive oxygen species (ROS) and nitric oxide (NO) while inhibitingFormula:C25H18N2O3Purity:98%Color and Shape:SolidMolecular weight:394.42GW837016X
CAS:GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.Formula:C25H20ClFN4OSColor and Shape:SolidMolecular weight:478.97HJC0416
CAS:HJC0416 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.Formula:C18H17ClN2O4SPurity:98%Color and Shape:SolidMolecular weight:392.86HI5
CAS:HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.Formula:C42H43N5O8Color and Shape:SolidMolecular weight:745.82HDAC-IN-51
HDAC-IN-51 is an HDAC inhibitor.Formula:C27H24N4O2Purity:98.85%Color and Shape:SolidMolecular weight:436.51MX107
CAS:MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.Formula:C24H28N2O2Color and Shape:SolidMolecular weight:376.49CMLD012072
CAS:CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.Formula:C32H32N2O7Purity:98%Color and Shape:SolidMolecular weight:556.61PD-1/PD-L1-IN-20
CAS:PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction.Formula:C30H26BrClN2O3Color and Shape:SolidMolecular weight:577.9Undecylprodigiosin
CAS:Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.Formula:C25H35N3OColor and Shape:SolidMolecular weight:393.56AG6033
CAS:AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.Formula:C30H23N5O4Color and Shape:SolidMolecular weight:517.53HDAC-IN-31
CAS:HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.Formula:C25H24N4O2Color and Shape:SolidMolecular weight:412.48NSC 107512
CAS:NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.Formula:C12H16N6O5Color and Shape:SolidMolecular weight:324.297DG
CAS:7DG is a selective inhibitor of protein kinase R (PKR).Formula:C26H30O5Color and Shape:SolidMolecular weight:422.51MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormula:C29H30N2O5SColor and Shape:SolidMolecular weight:518.62DNA topoisomerase II inhibitor 1
CAS:Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.Formula:C28H24N4O3SColor and Shape:SolidMolecular weight:496.58CS1
CAS:CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.Formula:C16H12O3Color and Shape:SolidMolecular weight:252.26
