Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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HDAC1/2 and CDK2-IN-1
CAS:<p>Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.</p>Formula:C26H22ClN7OColor and Shape:SolidMolecular weight:483.95Nampt-IN-8
CAS:<p>Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.</p>Formula:C36H35N3O4Color and Shape:SolidMolecular weight:573.68NVX-207
CAS:<p>NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.</p>Formula:C36H59NO6Purity:98%Color and Shape:SolidMolecular weight:601.86SCAL-266
CAS:<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Formula:C27H28F3N5O2Purity:98%Color and Shape:SolidMolecular weight:511.54VU0424465
CAS:<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Formula:C19H19FN2O2Color and Shape:SolidMolecular weight:326.36AZD 1152 (hydrochloride)
CAS:<p>AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.</p>Formula:C26H33Cl2FN7O6PColor and Shape:SolidMolecular weight:660.47VEGFR-2/BRAF-IN-2
<p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>Formula:C26H21ClF3N5O3S2Color and Shape:SolidMolecular weight:608.05HDAC6-IN-4
CAS:<p>HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.</p>Formula:C30H38N2O5Color and Shape:SolidMolecular weight:506.63p-DDAP
CAS:<p>p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.</p>Formula:C18H31NOPurity:98%Color and Shape:SolidMolecular weight:277.44GW-3333
CAS:<p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>Formula:C22H36N4O4Purity:98%Color and Shape:SolidMolecular weight:420.55ARN5187
CAS:<p>ARN5187, a lysosomal REV-ERB β ligand, inhibits transcription and autophagy, shows efficacy, cytotoxicity, and induces apoptosis.</p>Formula:C24H32FN3OColor and Shape:SolidMolecular weight:397.53BRD0476
CAS:<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Formula:C35H38N4O8SPurity:98%Color and Shape:SolidMolecular weight:674.76Tubulin/MMP-IN-2
CAS:<p>Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.</p>Formula:C40H48NO11PColor and Shape:SolidMolecular weight:749.78Clidanac
CAS:<p>Clidanac is a potent anti-inflammatory drug and is found to uncouple the oxidative phosphorylation.</p>Formula:C16H19ClO2Purity:98%Color and Shape:SolidMolecular weight:278.77PDE4-IN-10
CAS:<p>PDE4-IN-10 (7a), potent PDE4B inhibitor, IC50 7.01μM; selective, stable, TNF-α blocking, non-toxic in vitro.</p>Formula:C18H13NColor and Shape:SolidMolecular weight:243.3TPB15
CAS:<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Formula:C18H9Cl4N5OColor and Shape:SolidMolecular weight:453.11CDK6/PIM1-IN-1
CAS:<p>CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.</p>Formula:C25H28FN9Color and Shape:SolidMolecular weight:473.55MBM-17S
CAS:<p>MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and</p>Formula:C36H40N6O10Purity:98%Color and Shape:SolidMolecular weight:716.74CB-64D
CAS:<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Formula:C22H23NO2Color and Shape:SolidMolecular weight:333.42Quinate
CAS:<p>Quinate: oral antiarrhythmic, inhibits P450db, blocks K+ channels (IC50 19.9 μM), used in malaria research.</p>Formula:C26H36N2O9Color and Shape:SolidMolecular weight:520.579AMC-01
CAS:<p>AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51.</p>Formula:C27H27BrN2O6Purity:99.95%Color and Shape:SolidMolecular weight:555.42Luxeptinib
CAS:<p>Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.</p>Formula:C25H17F4N5O2Color and Shape:SolidMolecular weight:495.43MRS 2693 trisodium salt
CAS:<p>MRS 2693 trisodium salt is a P2Y6 agonist.</p>Formula:C9H22IN5O12P2Purity:98%Color and Shape:SolidMolecular weight:581.15673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27Anticancer agent 59
<p>Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.</p>Formula:C42H59NO6Color and Shape:SolidMolecular weight:673.92MPT0B392
CAS:<p>MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.</p>Formula:C19H20N2O6SColor and Shape:SolidMolecular weight:404.44Anticancer agent 99
CAS:<p>Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.</p>Formula:C19H20F3N3O2Color and Shape:SolidMolecular weight:379.38Thioxodihydroquinazolinone-19
CAS:<p>Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.</p>Formula:C16H14N2OSPurity:98%Color and Shape:SolidMolecular weight:282.36hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Formula:C23H21N3O5Color and Shape:SolidMolecular weight:419.43IW-927
CAS:<p>IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.</p>Formula:C22H23N3O3S2Color and Shape:SolidMolecular weight:441.57hGGPPS-IN-1
CAS:<p>HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.</p>Formula:C13H13N3O6P2SColor and Shape:SolidMolecular weight:401.272,5-Dihydroxybiphenyl
CAS:<p>2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.</p>Formula:C12H10O2Purity:99.66%Color and Shape:White To Grey-Brownish PowderMolecular weight:186.21Atopaxar Hydrobromide
CAS:<p>Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Formula:C29H39BrFN3O5Purity:98%Color and Shape:SolidMolecular weight:608.54Anticancer agent 58
<p>Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.</p>Formula:C39H55NO5Color and Shape:SolidMolecular weight:617.86FW1256
CAS:<p>FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.</p>Formula:C12H10NOPSColor and Shape:SolidMolecular weight:247.257DG
CAS:<p>7DG is a selective inhibitor of protein kinase R (PKR).</p>Formula:C26H30O5Color and Shape:SolidMolecular weight:422.51Justicidin B
CAS:<p>Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.</p>Formula:C21H16O6Color and Shape:SolidMolecular weight:364.35ENMD-1068 HCl
CAS:<p>ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.</p>Formula:C15H29N3O2Purity:99.91%Color and Shape:SolidMolecular weight:283.41NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Formula:C27H24F3N3O3Color and Shape:SolidMolecular weight:495.49SS28
CAS:<p>SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.</p>Formula:C18H20O3Purity:98%Color and Shape:SolidMolecular weight:284.35DRAK1/2-IN-1
CAS:<p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>Formula:C22H24N2O3SColor and Shape:SolidMolecular weight:396.5ISC-4
CAS:<p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>Formula:C11H13NSeColor and Shape:SolidMolecular weight:238.19PD-1-IN-18
CAS:<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Formula:C11H17N5O8Purity:98%Color and Shape:SolidMolecular weight:347.28Caspase-3-IN-1
CAS:<p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>Formula:C26H25N3O6SColor and Shape:SolidMolecular weight:507.56Anticancer agent 76
CAS:<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Formula:C32H33NO5SColor and Shape:SolidMolecular weight:543.67Epinephrine bitartrate
CAS:<p>L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.</p>Formula:C13H19NO9Purity:98.6% - 99.07%Color and Shape:White SolidMolecular weight:333.3RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Formula:C23H24N4O4SColor and Shape:SolidMolecular weight:452.53PD-1/PD-L1-IN-28
CAS:<p>PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.</p>Formula:C24H24N4O2Color and Shape:SolidMolecular weight:400.47SID 3712249
CAS:<p>SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).</p>Formula:C17H21N7Purity:98%Color and Shape:SolidMolecular weight:323.4SKI-I
CAS:<p>SKI-I: Human sphingosine kinase inhibitor, IC50 1.2μM; hERK2 inhibitor, IC50 11μM; promotes tumor cell apoptosis.</p>Formula:C25H18N4O2Color and Shape:SolidMolecular weight:406.44HDACs/mTOR Inhibitor 1
CAS:<p>HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,</p>Formula:C28H38N8O5Color and Shape:SolidMolecular weight:566.65Antitumor agent-56
CAS:<p>Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.</p>Formula:C28H28N2O10SColor and Shape:SolidMolecular weight:584.59Aurora A inhibitor 2
CAS:<p>Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).</p>Formula:C24H26N6O3Color and Shape:SolidMolecular weight:446.5Mammea A/BA
CAS:<p>Mammea A/BA combats T. cruzi by causing mitochondrial damage, ROS, DNA fragmentation, and vacuolization, leading to cell death. Useful for Chagas research.</p>Formula:C25H26O5Color and Shape:SolidMolecular weight:406.47Topoisomerase II inhibitor 11
CAS:<p>Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).</p>Formula:C27H21BrCl2N2O2SColor and Shape:SolidMolecular weight:588.34Ro 31-7837
CAS:<p>Ro 31-7837 is an opener of potassium channel.</p>Formula:C17H16N2O2Color and Shape:SolidMolecular weight:280.32EAPB 02303
CAS:<p>EAPB 02303, a microtubule inhibitor, induces mitotic arrest, spindle impairment, apoptosis, and has antitumor effects, enhancing Paclitaxel.</p>Formula:C17H14N4O2Color and Shape:SolidMolecular weight:306.32Tubulin polymerization-IN-17
CAS:<p>Compound 23g, a potent inhibitor of tubulin aggregation, induces apoptosis, and inhibits cell migration; promising for cancer research.</p>Formula:C26H23NO5Color and Shape:SolidMolecular weight:429.46Ludartin
CAS:<p>Ludartin activates TRPA1, induces DNA damage, and lowers mitochondrial potential, yielding anticancer effects.</p>Formula:C15H18O3Color and Shape:SolidMolecular weight:246.3Anti-inflammatory agent 17
CAS:<p>Compound 17: Orally active, potent IL-6 & TNF-α inhibitor; not cytotoxic; promising for ALI research.</p>Formula:C20H23NO5Color and Shape:SolidMolecular weight:357.4HS-438
CAS:<p>HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.</p>Formula:C17H17N3O3SColor and Shape:SolidMolecular weight:343.4Anticancer agent 71
CAS:<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Formula:C18H13ClF3N5OColor and Shape:SolidMolecular weight:407.78RET-IN-15
CAS:<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Formula:C27H28N8O2Color and Shape:SolidMolecular weight:496.56EGFR-IN-57
CAS:<p>EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.</p>Formula:C22H15N3O2SColor and Shape:SolidMolecular weight:385.44AQX-016A
CAS:<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Formula:C22H32O2Color and Shape:SolidMolecular weight:328.49AG311
CAS:<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Formula:C17H15N5SColor and Shape:SolidMolecular weight:321.4AP23464
CAS:<p>AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.</p>Formula:C26H30N5O2PColor and Shape:SolidMolecular weight:475.52Antitumor agent-57
CAS:<p>Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.</p>Formula:C20H15NO5Color and Shape:SolidMolecular weight:349.34CMC2.24
CAS:<p>CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.</p>Formula:C26H21NO5Color and Shape:SolidMolecular weight:427.45PI3K-IN-33
CAS:<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Formula:C23H21BrN6O2Color and Shape:SolidMolecular weight:493.36PI3Kδ-IN-11
CAS:<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Formula:C27H21N5OColor and Shape:SolidMolecular weight:431.49ACA-28
CAS:<p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>Formula:C17H16O6Purity:98.73%Color and Shape:SolidMolecular weight:316.31CDK1/2/4-IN-1
CAS:<p>CDK1/2/4-IN-1 inhibits CDKs (IC50: CDK1-1.47μM; CDK2-0.78μM; CDK4-0.87μM) and is useful in cancer studies, affecting apoptosis and the cell cycle.</p>Formula:C15H16N2O2SColor and Shape:SolidMolecular weight:288.36(Rac)-Indoximod
CAS:<p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>Formula:C12H14N2O2Color and Shape:SolidMolecular weight:218.25(S)-Erypoegin K
CAS:<p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>Formula:C20H18O6Color and Shape:SolidMolecular weight:354.35Anticancer agent 56
CAS:<p>Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.</p>Formula:C20H18ClN3O3Color and Shape:SolidMolecular weight:383.83Adapalene sodium salt
CAS:<p>Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.</p>Formula:C28H28NaO3Purity:98%Color and Shape:SolidMolecular weight:435.519EGFR-IN-56
CAS:<p>EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.</p>Formula:C23H22N4O3SColor and Shape:SolidMolecular weight:434.51Anticancer agent 42
CAS:<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Formula:C19H16Cl2N2O3Color and Shape:SolidMolecular weight:391.25CDK/HDAC-IN-2
CAS:<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Formula:C25H20Cl2N6O3Color and Shape:SolidMolecular weight:523.37PQ1 Succinate
CAS:<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Formula:C25H28F3N3O6Color and Shape:SolidMolecular weight:523.5TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Formula:C20H21N5OSColor and Shape:SolidMolecular weight:379.48NSC114792
CAS:<p>NSC114792 is a selective JAK3 inhibitor.</p>Formula:C26H32N4O2SPurity:98%Color and Shape:SolidMolecular weight:464.62p-nitro-Pifithrin-α
CAS:<p>p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.</p>Formula:C15H16BrN3O3SColor and Shape:SolidMolecular weight:398.27MI-63
CAS:<p>MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.</p>Formula:C29H35Cl2FN4O3Color and Shape:SolidMolecular weight:577.52Anticancer agent 72
CAS:<p>Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.</p>Formula:C20H19N7O2Color and Shape:SolidMolecular weight:389.41TRK-IN-23
CAS:<p>TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,</p>Formula:C20H17FN4O2Purity:98%Color and Shape:SolidMolecular weight:364.37DBIBB
CAS:<p>DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.</p>Formula:C23H20N2O6SPurity:98.49% - 99.1%Color and Shape:SolidMolecular weight:452.48Topoisomerase II inhibitor 10
CAS:<p>Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM).</p>Formula:C27H20N6O7SColor and Shape:SolidMolecular weight:572.55Alteminostat
CAS:<p>Alteminostat is used as a histone deacetylase inhibitor and is an antineoplastic drug candidate.</p>Formula:C27H36N6O3Color and Shape:SolidMolecular weight:492.61IDO1/TDO-IN-1
CAS:<p>IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.</p>Formula:C21H16O6Color and Shape:SolidMolecular weight:364.35Quinidine polygalacturonate
CAS:<p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>Formula:C26H34N2O9Color and Shape:SolidMolecular weight:518.22643BLM-IN-2
<p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>Formula:C33H38BrFN4OColor and Shape:SolidMolecular weight:605.58SIRT6 activator 12q
CAS:<p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>Formula:C31H22N2O2Color and Shape:SolidMolecular weight:454.52CEP-1612
CAS:<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Formula:C35H53N7O7Color and Shape:SolidMolecular weight:683.84BLM-IN-1
CAS:<p>BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.</p>Formula:C28H35FN4OColor and Shape:SolidMolecular weight:462.6SKLB0565
CAS:<p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>Formula:C20H25ClN6OColor and Shape:SolidMolecular weight:400.91Anticancer agent 66
CAS:<p>Anticancer agent 66, a ciprofloxacin analog, triggers apoptosis in MCF-7 cells.</p>Formula:C26H23Cl2FN6O2S2Color and Shape:SolidMolecular weight:605.53Mcl1-IN-3
CAS:<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Formula:C27H22ClN3O4Purity:98%Color and Shape:SolidMolecular weight:487.93Infliximab
CAS:<p>Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.</p>Purity:98% - 99.70%Color and Shape:LiquidMolecular weight:149 kDa
