Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6068 products of "Apoptosis"
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Aurora A inhibitor 2
CAS:Aurora A inhibitor 2 (Compound 16h) is a potent inhibitor of Aurora A kinase (IC50: 21.94 nM).Formula:C24H26N6O3Color and Shape:SolidMolecular weight:446.5Antitumor agent-56
CAS:Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.Formula:C28H28N2O10SColor and Shape:SolidMolecular weight:584.59MEK-IN-5
CAS:MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.Formula:C29H27FN4O10S2Color and Shape:SolidMolecular weight:674.67Atopaxar
CAS:Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H38FN3O5Purity:97.07% - 98.07%Color and Shape:SolidMolecular weight:527.63VS 8
CAS:VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.Formula:C26H20F3N3O3Color and Shape:SolidMolecular weight:479.45RIPK1-IN-11
CAS:RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.Formula:C23H24N4O4SColor and Shape:SolidMolecular weight:452.53Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Formula:C29H30N6O2Color and Shape:SolidMolecular weight:494.59XMD15-44
CAS:XMD15-44, a RET kinase inhibitor, demonstrates potent growth-inhibitory effects on RAT1 cells transformed by RET/C634R and RET/M918T, with IC50 values of 11.5 nM and 8.3 nM, respectively. It effectively inhibits RET kinase activity and signaling in human thyroid cancer cell lines harboring oncogenic RET alleles, thereby reducing cell proliferation.Formula:C29H29F3N4OMolecular weight:506.56PHA-690509
CAS:PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.Formula:C17H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:331.43Antitumor agent-115
CAS:Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line.Formula:C19H38ClNO2Purity:98%Color and Shape:SolidMolecular weight:347.96PERK-IN-3
CAS:PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).Formula:C22H16F2N4O2Purity:98%Color and Shape:SolidMolecular weight:406.38Metoprolol fumarate
CAS:Metoprolol fumarate (CGP 2175C): selective β1-blocker with anti-inflammatory, antitumor, anti-angiogenic effects.Formula:C34H54N2O10Color and Shape:SolidMolecular weight:650.8Shield-2
CAS:Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.Formula:C35H51N3O7Purity:98%Color and Shape:SolidMolecular weight:625.8Tubulin polymerization-IN-14
CAS:Tubulin-IN-14 (20a) inhibits polymerization (IC50=3.15μM), has anti-cancer and anti-vascular effects, inducing cell death.Formula:C15H15ClN2O2Color and Shape:SolidMolecular weight:290.74CS1
CAS:CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.Formula:C16H12O3Color and Shape:SolidMolecular weight:252.26DNA topoisomerase II inhibitor 1
CAS:Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.Formula:C28H24N4O3SColor and Shape:SolidMolecular weight:496.58Anisperimus
CAS:<p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>Formula:C18H39N7O3Purity:98.10%Color and Shape:SolidMolecular weight:401.55MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormula:C29H30N2O5SColor and Shape:SolidMolecular weight:518.62CSRM617
CAS:CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.Formula:C10H13N3O5Purity:98%Color and Shape:SolidMolecular weight:255.23EGFR/BRAFV600E-IN-1
CAS:EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).Formula:C24H24ClN3O3Color and Shape:SolidMolecular weight:437.92
