Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(8 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6084 products of "Apoptosis"
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Necrostatin-5
CAS:Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.Formula:C19H17N3O2S2Purity:99.40%Color and Shape:SolidMolecular weight:383.49RET-IN-23
CAS:RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.Formula:C28H28FN11Purity:97.46%Color and Shape:SolidMolecular weight:537.591G244
CAS:1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.Formula:C29H30F2N4O2Purity:99.14%Color and Shape:SolidMolecular weight:504.57UK-101
CAS:UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μMFormula:C25H48N2O5SiPurity:98.97% - 99.08%Color and Shape:SolidMolecular weight:484.74AQ4
CAS:AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.Formula:C22H28N4O4Purity:96.28% - 97.15%Color and Shape:SolidMolecular weight:412.48W146
CAS:W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.Formula:C16H27N2O4PPurity:99.37%Color and Shape:SolidMolecular weight:342.37Brigimadlin
CAS:Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.Formula:C31H25Cl2FN4O3Purity:98.17%Color and Shape:SolidMolecular weight:591.46Ref: TM-T69923
1mg159.00€5mg271.00€10mg373.00€25mg610.00€50mg929.00€100mg1,388.00€1mL*10mM (DMSO)354.00€CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formula:C20H22N2O6Purity:98.19%Color and Shape:SolidMolecular weight:386.4Apostatin-1
CAS:Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Formula:C19H27N3OSPurity:99.31%Color and Shape:SolidMolecular weight:345.5Ref: TM-T9079
1mg37.00€2mg52.00€5mg79.00€10mg119.00€25mg235.00€50mg378.00€100mg560.00€500mg1,216.00€1mL*10mM (DMSO)87.00€p53-MDM2-IN-1
CAS:<p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>Formula:C23H20ClN3O3Purity:99.98%Color and Shape:SoildMolecular weight:421.88Lanperisone HCl
CAS:Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.Formula:C15H19ClF3NOPurity:98.67% - >99.99%Color and Shape:SolidMolecular weight:321.77MMRi64
CAS:MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.Formula:C22H17Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:410.3K-8012
CAS:K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.Formula:C23H23FN4Purity:99.72%Color and Shape:SolidMolecular weight:374.45Ref: TM-T24240
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,157.00€1mL*10mM (DMSO)266.00€Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Formula:C42H50FN7O8S2Purity:99.05%Color and Shape:SolidMolecular weight:864.02HTH-01-091
CAS:HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,Formula:C26H28Cl2N4O2Purity:98.82%Color and Shape:SolidMolecular weight:499.43Ref: TM-T24152
1mg281.00€5mg692.00€10mg938.00€25mg1,454.00€50mg1,882.00€100mg2,375.00€1mL*10mM (DMSO)775.00€Vamotinib
CAS:Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.Formula:C29H27F3N6OPurity:99.64%Color and Shape:SolidMolecular weight:532.56Ref: TM-T63746
1mg106.00€5mg259.00€10mg424.00€25mg757.00€50mg1,035.00€100mg1,415.00€200mg1,882.00€1mL*10mM (DMSO)304.00€HBED
CAS:HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.Formula:C20H24N2O6Purity:97.35% - 98.58%Color and Shape:SolidMolecular weight:388.41H2L5186303
CAS:H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.Formula:C26H20N2O8Purity:98.19%Color and Shape:SolidMolecular weight:488.45Ref: TM-T22835
2mg44.00€5mg64.00€10mg94.00€25mg180.00€50mg283.00€100mg465.00€200mg642.00€1mL*10mM (DMSO)75.00€EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Formula:C29H35N9O2SPurity:99.93%Color and Shape:SolidMolecular weight:573.71GSK-3β inhibitor 3
CAS:GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3Formula:C18H14FNO2SPurity:97.53%Color and Shape:SolidMolecular weight:327.37Ref: TM-T35554
1mg92.00€5mg188.00€10mg283.00€25mg530.00€50mg795.00€100mg1,169.00€1mL*10mM (DMSO)215.00€
