Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(27 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6059 products of "Apoptosis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Thalidomide-O-PEG4-Boc
CAS:Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].Formula:C28H38N2O11Purity:98%Color and Shape:SolidMolecular weight:578.61C-Met/Axl-IN-1
C-Met/Axl-IN-1 (Compound 22a) is an oral, selective type II c-Met/Axl inhibitor with IC50 values of 1 nM and 10 nM, respectively. It effectively suppresses tumor cell proliferation, induces cell cycle arrest, and apoptosis (apoptosis), showcasing potent anti-tumor activity.Formula:C25H18F2N6O2Color and Shape:SolidMolecular weight:472.45PROTAC EGFR degrader 5
CAS:PROTAC EGFR degrader 5 effectively breaks down EGFR Del19 in HCC827 cells at 34.8 nM, inducing apoptosis and G1 arrest.Formula:C57H72FN13O5SColor and Shape:SolidMolecular weight:1070.33Rosomidnar
CAS:PNT100: 24-base DNA oligo targeting BCL-2 regulatory region; halts tumor cell growth, induces death.Formula:C227H291O141P23Color and Shape:SolidMolecular weight:7220.63N-Deshydroxyethyl Dasatinib
CAS:N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAPFormula:C20H22ClN7OSPurity:95.96%Color and Shape:SolidMolecular weight:443.95Fludarabine triphosphate trisodium
Fludarabine triphosphate (F-ara-ATP) trisodium inhibits DNA synthesis; IC50 2.3 μM, Ki 6.1 μM, blocks DNA primase, prompts apoptosis.Formula:C10H12FN5Na3O13P3Color and Shape:SolidMolecular weight:591.12CYP51/PD-L1-IN-1
CYP51/PD-L1-IN-1 (compound L11), a quinazoline with antifungal properties, simultaneously inhibits CYP51 (IC50: 0.884 μM) and PD-L1 (IC50: 0.083 μM).Formula:C20H15N5O2Color and Shape:SolidMolecular weight:357.37YB-0158 ammonium
YB-0158 ammonium (Wnt pathway inhibitor 2 ammonium) is a reverse-rotation peptidomimetic with translation-enhancing potential and anticancer activity.Formula:C32H40N9O7PPurity:99.14% - 99.18%Color and Shape:SolidMolecular weight:693.69HJC0416 hydrochloride
CAS:HJC0416 hydrochloride: potent oral STAT3 inhibitor, better anticancer effects than Stattic, promising for breast cancer research.Formula:C18H18Cl2N2O4SColor and Shape:SolidMolecular weight:429.31Placulumab
CAS:Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.Color and Shape:LiquidAM-8553
CAS:AM-8553 is potent and selective piperidine the MDM2-p53 interaction inhibitor.Formula:C25H29Cl2NO4Color and Shape:SolidMolecular weight:478.41Manelimab
CAS:Manelimab is a monoclonal antibody that inhibits programmed death-ligand 1 ( PD-L1 ) [1] .Color and Shape:LiquidMI-1061 TFA
CAS:MI-1061 TFA: potent MDM2 inhibitor, orally bioavailable, stable (IC50=4.4 nM, Ki=0.16 nM), activates p53, induces apoptosis in mice tumors.Formula:C32H27Cl2F4N3O6Color and Shape:SolidMolecular weight:696.47Fosbretabulin [free base]
CAS:<p>Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels.</p>Formula:C18H21O8PColor and Shape:SolidMolecular weight:396.33Multi-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.Formula:C21H20ClFN2OSPurity:98%Color and Shape:SolidMolecular weight:402.91Thalidomide-NH-PEG4-COOH
CAS:Thalidomide-NH-PEG4-COOH is a E3 ligase ligand-linker for synthesizing the selective degrader dCBP-1 targeting p300/CBP.Formula:C24H31N3O10Color and Shape:SolidMolecular weight:521.523Tasisulam sodium
CAS:Tasisulam triggers apoptosis, halts mitosis, and normalizes blood vessels to combat cancer.Formula:C11H5BrCl2NNaO3S2Color and Shape:SolidMolecular weight:437.09Valproic acid sodium salt
CAS:Sodium valproate is an anti-epileptic, boosting brain GABA levels and possibly affecting potassium channels for membrane stability.Formula:C8H15NaO2Purity:98% - 99.78%Color and Shape:White PowderMolecular weight:166.2Asunercept
CAS:Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.Color and Shape:LiquidNecroptosis-IN-3
CAS:Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis.Formula:C12H17NOSPurity:99.85%Color and Shape:SoildMolecular weight:223.33
![Fosbretabulin [free base]](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT31857.webp&w=3840&q=75)
