Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(27 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(93 products)
- c-RET(62 products)
- p53(63 products)
Show 6 more subcategories
Found 6063 products of "Apoptosis"
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Linsidomine hydrochloride
CAS:SIN-1 chloride is a moxidomine metabolite with vasodilatory, anti-platelet, and antianginal effects, reducing myocardial ischemia-related damage.Formula:C6H11ClN4O2Purity:99.27% - 99.67%Color and Shape:White Solid CrystallineMolecular weight:206.631,2,3,4-Tetrahydronaphthalen-2-ol
CAS:1,2,3,4-Tetrahydronaphthalen-2-ol exhibits weak inhibitory activity against Bcl-xL and is widely used in biochemical experiments and drug synthesis research.Formula:C10H12OColor and Shape:SolidMolecular weight:148.2Thalidomide-5-propoxyethanamine
CAS:<p>Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of recruiting the CRBN protein.</p>Formula:C18H21N3O5Color and Shape:SolidMolecular weight:359.38Isomahanine
Isomahanine is a useful organic compound for research related to life sciences and the catalog number is T125848.Formula:C23H25NO2Color and Shape:SolidMolecular weight:347.458TNF-α (31-45), human
CAS:TNF-α (31-45), human is a peptide of tumor necrosis factor-α.Formula:C69H122N26O22Purity:98%Color and Shape:SolidMolecular weight:1667.895Pomalidomide-C5-Dovitinib
CAS:Pomalidomide-C5-Dovitinib (compound 2) is a PROTAC that links Pomalidomide and Dovitinib via a CRBN connector, exhibiting potent antiproliferative activity inFormula:C39H38FN9O6Purity:98%Color and Shape:SolidMolecular weight:747.77Type-I/-II Photosensitizer-1
Type-I/-II Photosensitizer-1 (compound 8b) is a photosensitizer with anticancer properties. It exhibits significant phototoxicity against A549 and 4T1 tumor cells. Under laser irradiation, Type-I/-II Photosensitizer-1 demonstrates strong oxygen-independent antitumor activity with an IC50 ranging from 1.50 to 1.76 μM.Formula:C60H48F12N8P2RuColor and Shape:SolidMolecular weight:1272.07Polyphyllin G
CAS:Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas.Formula:C51H84O22Purity:98%Color and Shape:SolidMolecular weight:1049.21CV-4-26
CV-4-26 (Compound 22) acts as a covalent inhibitor of TEAD. By inhibiting YAP/TEAD-driven transcription, it diminishes the expression of CTGF and CYR61. Furthermore, CV-4-26 impedes colony formation in Huh7 and HepG2 cells, inducing cell cycle arrest and apoptosis (apoptosis). This compound demonstrates anti-tumoral activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB).Color and Shape:Odour SolidYL5084
CAS:YL5084 is a selective JNK2/3 inhibitor with IC50s: JNK2 (70 nM), JNK3 (84 nM), and antiproliferative, apoptosis-inducing effects.Formula:C35H36N8O2Color and Shape:SolidMolecular weight:600.71Trimebutine
CAS:Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioidFormula:C22H29NO5Purity:99.49% - 99.86%Color and Shape:SolidMolecular weight:387.47(E/Z)-LAQ824
CAS:(E/Z)-LAQ824 is an inhibitor of histone deacetylase.Formula:C22H25N3O3Purity:98%Color and Shape:SolidMolecular weight:379.46Bcl-2-IN-22
<p>Bcl-2-IN-22 (compound 1), a gold (I) NHC complex, exhibits anticancer activity. It induces cell death (apoptosis) via the mitochondrial pathway with an IC50 value of 0.014 μM. Additionally, Bcl-2-IN-22 targets members of the BCL-2 family, promoting apoptosis and sensitization in multidrug-resistant leukemia cells overexpressing BCL-2.</p>Color and Shape:Odour SolidCDK/HDAC-IN-4
CDK/HDAC-IN-4 is a highly selective dual inhibitor of cyclin-dependent kinase (CDK) and histone deacetylase (HDAC), with IC50 values of 88.4 nM and 168.9 nM, respectively. This compound exhibits antiproliferative effects in both hematologic and solid tumor cells. Additionally, CDK/HDAC-IN-4 induces apoptosis and S-phase cell cycle arrest in MV-4-11 cells. It has also demonstrated significant antitumor efficacy in an MV-4-11 xenograft model.Color and Shape:Odour SolidPD-L1/VISTA-IN-2
PD-L1/VISTA-IN-2 (Compound S8) is an orally active dual inhibitor targeting PD-L1 and VISTA, with an IC50 of 1.4 μM for PD-L1 and a KD of 2.1 μM for VISTA. This compound can activate the tumor immune microenvironment, exerting anticancer effects.Formula:C22H22N2O3Color and Shape:SolidMolecular weight:362.42Ro 48-8071
CAS:Oxidosqualene cyclase inhibitorFormula:C23H27BrFNO2Purity:98%Color and Shape:SolidMolecular weight:448.37p53 and MDM2 proteins-interaction-inhibitor dihydrochloride
p53 and MDM2 proteins-interaction-inhibitor dihydrochloride is a interaction inhibitor between p53 and MDM2 proteins.Formula:C40H51Cl4N5O4Purity:98%Color and Shape:SolidMolecular weight:807.68DB818 dihydrochloride
DB818 dihydrochloride is the dihydrochloride salt form of DB818. It acts as an inhibitor of Homeobox A9 (HOXA9). By reducing the formation of the HOXA9-DNA complex, DB818 dihydrochloride inhibits the growth of AML cell lines OCI/AML3, MV4-11, and THP-1 and induces cell apoptosis (apoptosis).Color and Shape:Odour SolidFW-1
<p>FW-1 is a type I inhibitor of FLT3, with an IC50 of approximately 1 μM. It exhibits cytotoxic effects in FLT3-mutant AML cells, causes cell cycle arrest at the G0/G1 phase, and induces apoptosis in MV4-11 and MOLM-13 cells.</p>Formula:C24H27N7OColor and Shape:SolidMolecular weight:429.517Src Inhibitor 4
Src Inhibitor4 (Compound 18) is a derivative of KX-01 and functions as a Src inhibitor. It effectively disrupts tumor cells, damages microtubules, and induces cell cycle arrest, apoptosis, and immunogenic cell death. After introducing phenol or aniline functional groups, Src Inhibitor4 serves as a payload conjugation site for antibody-drug conjugates, showcasing antitumor activity.Formula:C33H34N4O3Color and Shape:SolidMolecular weight:534.648
