Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(8 products)
- Caspase(147 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(140 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(19 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6114 products of "Apoptosis"
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5-LOX-IN-2
CAS:5-LOX-in-2: a 5-lipoxygenase inhibitor with IC50 of 0.33 μM, reduces kidney cancer cell activity, induces apoptosis.Formula:C17H16O4Purity:98.74%Color and Shape:SoildMolecular weight:284.31Anticancer agent 136
Anticancer agent 136 (compound 22), a C17-triazole analogue of Geldanamycin (GDM), exhibits an IC50 value of 3.38 μM against human dermal fibroblasts (HDF) andFormula:C40H50N6O8Purity:98%Color and Shape:SolidMolecular weight:742.86Anticancer agent 146
Anticancer Agent 146 (Compound 1.19) acts as a necroptosis inducer and demonstrates anti-tumor efficacy in the MDA-MB-231 mouse xenograft model [1].Formula:C19H16Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:375.25Antimycin A2c
Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer.Formula:C28H40N2O9Purity:98%Color and Shape:SolidMolecular weight:548.63Anticancer agent 133
Compound Rh2 (Anticancer agent 133) is a cytotoxic and antimetastatic agent that induces cell cycle arrest, apoptosis, and autophagy.Formula:C24H19Cl3N5ORhPurity:98%Color and Shape:SolidMolecular weight:602.71fac-[Re(CO)3(L6)(H2O)][NO3]
Compound 6, fac-[Re(CO)3(L6)(H2O)][NO3], a rhenium(I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function.Formula:C24H14N5O7ReSPurity:98%Color and Shape:SolidMolecular weight:702.67TAT-NEP1-40
TAT-NEP1-40, a blood-brain barrier (BBB) permeable peptide, confers protection to PC12 cells against oxygen and glucose deprivation (OGD) while promotingFormula:C268H438N88O77Purity:98%Color and Shape:SolidMolecular weight:6124.89CPT2
CAS:Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC).Purity:98%Color and Shape:SolidCholicamideβ
Cholicamideβ (compound 6), a self-assembling small molecule cancer vaccine adjuvant, forms low cytotoxicity virus-like particles and upon binding to peptideFormula:C55H94N2O6Purity:98%Color and Shape:SolidMolecular weight:879.34TAT-GluN2BCTM
CAS:TAT-GluN2BCTM is a membrane-permeable peptide that selectively targets active DAPK1 (Death-associated protein kinase 1) for lysosomal degradation, therebyFormula:C224H374N86O54Purity:98%Color and Shape:SolidMolecular weight:5135.91Antitumor photosensitizer-4
Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2.Formula:C65H77ClN12O11SPurity:98%Color and Shape:SolidMolecular weight:1269.9cpm-1285
CAS:CPM-1285 induces apoptosis by effectively inhibiting the function of intracellular Bcl-2 and associated death antagonists.Formula:C153H240N44O42SPurity:98%Color and Shape:SolidMolecular weight:3399.88Anticancer agent 132
Compound Rh1 (Anticancer agent 132) acts as an inducer of apoptosis and autophagy, exhibiting both antitumor and antimetastatic activities.Formula:C24H16Cl3F3N5ORhPurity:98%Color and Shape:SolidMolecular weight:656.68Antitumor agent-103
Antitumor Agent-103 (compound 24l) induces apoptosis and possesses antiproliferative and anti-colony formation properties.Formula:C36H36N8O9S2Purity:98%Color and Shape:SolidMolecular weight:788.85Anticancer agent 153
Anticancer Agent 153 (Compound 3) promotes apoptosis through the generation of Reactive Oxygen Species (ROS) and elevates the loss of Mitochondrial Membrane
Formula:C16H11Cl2N3O3Purity:98%Color and Shape:SolidMolecular weight:364.18HNPMI
CAS:HNPMI is an epidermal growth factor receptor inhibitor that promotes apoptosis and is used in the study of colorectal cancer.Formula:C22H20N2O3Purity:97.19%Color and Shape:SoildMolecular weight:360.412-aminobenzo[d]thiazol-6-ol
CAS:2-aminobenzo[d]thiazol-6-ol: antimicrobial, antioxidant, anticancer; may trigger cancer cell apoptosis.Formula:C7H6N2OSPurity:98.92%Color and Shape:SolidMolecular weight:166.2Pyridinium bisretinoid A2E
CAS:Pyridinium bisretinoid A2E (A2E) is a fluorescent molecule isolated from the lipofuscin of retinal pigment epithelium, a weak photosensitizer.Formula:C42H58NOPurity:83.65%Color and Shape:SolidMolecular weight:592.92Topoisomerase II inhibitor 17
TopoisomeraseII inhibitor 17 (compound 4c) is a thiazolopyrimidine-based inhibitor of Topoisomerase II with an IC50 of 0.23 μM. This compound significantly disrupts the cell cycle and induces apoptosis.Formula:C25H22Cl3N3O5SMolecular weight:581.03458Ru-Poma
Ru-Poma is an Ru(II)-based photosensitizer designed to enhance the efficacy of photodynamic therapy (PDT) against tumors resistant to Cisplatin. It targets Pomalidomide to partially degrade CRBN, inducing ferroptosis by increasing lipid peroxides and downregulating GPX4 and GAPDH expression. In A549 cells, Ru-Poma exhibits cytotoxicity with IC50 values of 18.46 μM in the dark and 0.37 μM under illumination.Formula:C89H75Cl2N11O11Ru·7H2O
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