Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5599 products of "Apoptosis"
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CHM-1
CAS:<p>CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity.</p>Formula:C16H10FNO3Purity:99.839%Color and Shape:SolidMolecular weight:283.25Famitinib malate
CAS:<p>Famitinib malate (SHR1020) is a potent oral kinase inhibitor targeting c-kit, VEGFR-2, and PDGFRβ, with IC50s 2.3, 4.7, 6.6 nM, useful for cancer research.</p>Formula:C27H33FN4O7Color and Shape:SolidMolecular weight:544.57JMJD3/HDAC-IN-1
CAS:<p>Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histone</p>Formula:C21H30N6O2Purity:98%Color and Shape:SolidMolecular weight:398.5YM281
CAS:<p>YM281 is a potent EZH2 inhibitor, causes apoptosis and G0/G1 arrest, has antitumor activity in vivo, and may be researched for lymphoma.</p>Formula:C56H71N7O9SColor and Shape:SolidMolecular weight:1018.27WF-210
CAS:<p>WF-210 is an effective activator of procaspase-3 that acts by inducing apoptosis in cancer cells and reducing tumor growth.</p>Formula:C41H38FN7O7SPurity:98%Color and Shape:SolidMolecular weight:791.85INU-152
CAS:<p>INU-152: pan-RAF inhibitor with potent anti-tumor effects on BRAFV600E cancers, inhibits MAPK in mutant cells, minimal side effects on RAS-mutant melanoma.</p>Formula:C20H13F2N7O3SPurity:98%Color and Shape:SolidMolecular weight:469.42BQZ-485
CAS:<p>BQZ-485, a potent GDI2 inhibitor, interacts with Tyr245 to disrupt the native GDI2-Rab1A interaction.</p>Formula:C32H39NO3Purity:98%Color and Shape:SolidMolecular weight:485.66MS-177
CAS:<p>MS-177 is a PROTAC EZH2 degrader that promotes cholangiocarcinoma growth through the EZH2-mediated WNT7B/β-catenin pathway.</p>Formula:C48H55N11O8Color and Shape:SolidMolecular weight:914.02CP-24879 hydrochloride
CAS:<p>CP-24879 HCl, a Δ5D/Δ6D dual-inhibitor, reduces liver lipid buildup and inflammation.</p>Formula:C11H18ClNOPurity:98.08%Color and Shape:SolidMolecular weight:215.72GCN2-IN-6
CAS:<p>GCN2-IN-6: Potent, oral GCN2/PERK inhibitor; IC50s - GCN2: 1.8 nM (enzymatic), 9.3 nM (cellular); PERK: 0.26 nM (enzymatic), 230 nM (cellular).</p>Formula:C19H12Cl2F2N4O3SPurity:95.04% - 98%Color and Shape:SolidMolecular weight:485.29Lactoferrin (17-41) acetate
CAS:<p>Lactoferrin 17-41 (Lactoferricin B) acetate, a peptide derived from bovine lactoferrin spanning residues 17-41, exhibits broad-spectrum antimicrobial properties against Gram-positive and Gram-negative bacteria, viruses, protozoa, and fungi. Additionally, this compound demonstrates antitumor activities [1] [2].</p>Formula:C143H226N46O33S3Color and Shape:SolidMolecular weight:3183.82Ethylene glycol dimethacrylate
CAS:<p>Ethylene glycol dimethacrylate, a methacrylate monomer, demonstrates cytotoxic and genotoxic impacts on human gingival fibroblasts (HGFs), elevating</p>Formula:C10H14O4Purity:98%Color and Shape:SolidMolecular weight:198.22N-Oleoyl serinol
CAS:<p>N-Oleoyl serinol, a ceramide analog, plays a crucial role in stem cell therapy by inhibiting the development of teratomas in stem cells. It triggers apoptosis in remaining pluripotent embryoid body-derived cells (EBCs), thwarts teratoma formation, and promotes the enrichment of EBC cells that proceed to neural differentiation post-transplantation [1].</p>Formula:C21H41NO3Color and Shape:SolidMolecular weight:355.563FLT3-IN-14
CAS:<p>FLT3-IN-14: FLT3 inhibitor; FLT3-WT IC50=5.6nM, FLT3-ITD IC50=1.4nM; blocks Y591 phosphorylation; G1 arrest; pro-apoptotic.</p>Formula:C25H24N6O2SColor and Shape:SolidMolecular weight:472.56CA-170
CAS:<p>PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.</p>Formula:C12H20N6O7Purity:98%Color and Shape:SolidMolecular weight:360.32HS148
CAS:<p>HS148 selectively inhibits DAPK3 (Ki 119 nM), reducing gastric cancer progression via ULK1-dependent autophagy and tumor suppression pathways.</p>Formula:C15H14FN5O2SPurity:98.024%Color and Shape:SolidMolecular weight:347.37Ferroptocide
CAS:<p>Ferroptocide is a thioredoxin inhibitor that induces iron death in cancer cells and can be used in breast cancer research.</p>Formula:C30H36ClN3O7Color and Shape:SolidMolecular weight:586.08Ro 41-5253
CAS:<p>Ro 41-5253 is a RARα antagonist with antitumor activity that inhibits the proliferation of ZR-75.1 estrogen receptor-positive breast cancer cells.</p>Formula:C28H36O5SPurity:98%Color and Shape:SolidMolecular weight:484.65BTM-3566
CAS:<p>BTM-3566 triggers ISR via OMA1, induces apoptosis in cancer cells, and is used to research DLBCL.</p>Formula:C24H23F4N3O2S2Purity:99.95%Color and Shape:SolidMolecular weight:525.58RUNX-IN-1
CAS:<p>RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with their</p>Formula:C71H88Cl2N24O11Purity:98%Color and Shape:SolidMolecular weight:1524.52ICL-CCIC-0019
CAS:<p>ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.</p>Formula:C26H44Br2N4Purity:99.54%Color and Shape:SolidMolecular weight:572.46Lacutoclax
CAS:<p>Lacutoclax (LP-108) is an orally active and selective Bcl-2 inhibitor with antitumor activity both in vivo and ex vivo，lymphoma and leukemia.</p>Formula:C48H55ClN8O7SColor and Shape:SolidMolecular weight:923.52(S)-Verapamil hydrochloride
CAS:(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.Formula:C27H39ClN2O4Color and Shape:SolidMolecular weight:491.06C 87
CAS:C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.Formula:C24H15ClN6O3SPurity:≥98%Color and Shape:SolidMolecular weight:502.93Nirogacestat dihydrobromide
CAS:<p>Potent γ-secretase inhibitor; IC50: 1.2 nM (cell), 6.2 nM (cell-free); lowers Aβ in mice/guinea pigs' brain, CSF, plasma.</p>Formula:C27H43Br2F2N5OColor and Shape:SolidMolecular weight:651.48MK-2206 free base
CAS:<p>MK-2206 free base is an allosteric Akt inhibitor that is both potent and selective, administered orally, exhibiting IC50 values of 8, 12, and 65 nM for Akt1,</p>Formula:C25H21N5OPurity:98%Color and Shape:SolidMolecular weight:407.47Boserolimab
CAS:<p>Boserolimab (MK-5890) is a chimeric, humanized IgG1κ antibody that targets the signaling regulatory protein CD27 in mice.</p>Color and Shape:LiquidRIPK1-IN-8
CAS:<p>RIPK1-IN-8 is an aminoimidazolopyridine and is a selective and potent inhibitor of RIPK1 (IC50: 4 nM).RIPK1-IN-8 has research potential in inflammatory diseases</p>Formula:C26H24F2N6O3Color and Shape:SolidMolecular weight:506.5Siremadlin (R Enantiomer)
CAS:<p>Siremadlin R Enantiomer is the R enantiomer of Siremadlin. Siremadlin is a potent and highly specific inhibitor of MDM-2/p53.</p>Formula:C26H24Cl2N6O4Purity:98%Color and Shape:SolidMolecular weight:555.41AAPK-25
CAS:<p>AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.</p>Formula:C21H13Cl2N3O2SPurity:97.05%Color and Shape:SolidMolecular weight:442.32Antitumor agent-60
CAS:<p>Antitumor agent-60 inhibits growth by targeting RAS-RAF, binding CRAF (Kd: 721.3 nM), boosting p53/ROS, causing apoptosis, and arresting G2/M phase.</p>Formula:C24H28O10SColor and Shape:SolidMolecular weight:508.54BRD4 Inhibitor-18
CAS:<p>BRD4 Inhibitor-18: potent (IC50: 110 nM), impairs MV-4-11 cell growth, disrupts G0/G1 phase, and induces apoptosis.</p>Formula:C26H26ClN3O3SColor and Shape:SolidMolecular weight:496.02MI-219
CAS:<p>MI-219 is a human double minute 2 (HDM2) inhibitor.</p>Formula:C27H32Cl2FN3O4Color and Shape:SolidMolecular weight:552.47Calicheamicin
CAS:<p>Calicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.</p>Formula:C55H74IN3O21S4Purity:98.22% - 98.78%Color and Shape:SolidMolecular weight:1368.35Ogremorphin
CAS:<p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>Formula:C21H17N3OSPurity:99.65% - 99.65%Color and Shape:SolidMolecular weight:359.44CR-1-31-B
CAS:<p>CR-1-31-B, a synthetic rocaglate, inhibits eIF4A, hinders protein synthesis initiation, and induces apoptosis in cancer cells.</p>Formula:C28H29NO8Color and Shape:SolidMolecular weight:507.539NSC194598
CAS:<p>NSC194598 is a p53 DNA-binding inhibitor, demonstrating an in vitro IC50 of 180 nM and an in vivo range of 2-40 μM.</p>Formula:C20H19N3OColor and Shape:SolidMolecular weight:317.38BTM-3528
CAS:<p>BTM-3528 is a mitochondrial protease OMA1 activator that induces an overactivation of the mitochondrial integrated stress response (ISR).</p>Formula:C24H19F4N3O2S2Purity:99.37% - 99.37%Color and Shape:SolidMolecular weight:521.55CNDAC
CAS:<p>CNDAC, a nucleoside analog, is a major metabolite of oral drug sapacitabine.</p>Formula:C10H12N4O4Purity:98%Color and Shape:SolidMolecular weight:252.23EAD1 TFA(1644388-26-0 Free base)
CAS:<p>EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis</p>Formula:C26H28Cl2F3N7O2Purity:97.41%Color and Shape:SolidMolecular weight:598.45TL02-59
CAS:<p>TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.</p>Formula:C32H34F3N5O4Purity:98.77%Color and Shape:SolidMolecular weight:609.64USP7-IN-3
CAS:<p>USP7-IN-3 is a potent and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7).</p>Formula:C29H31F3N6O3Purity:98%Color and Shape:SolidMolecular weight:568.59GNE-900
CAS:<p>GNE-900 is an ATP-competitive ChK1 inhibitor with selective and oral activity.GNE-900 inhibits ChKl and ChK2 with IC50 values of 0.0011 and 1.5 µM, respectively</p>Formula:C23H21N5Purity:97.18%Color and Shape:SolidMolecular weight:367.45DX3-235
CAS:<p>DX3-235 is an oxidative phosphorylation (OXPHOS) inhibitor on mitochondrial complex I function in galactose-containing media, resulting in reduced ATP.</p>Formula:C26H39N5O6S2Purity:99.97%Color and Shape:SolidMolecular weight:581.75HDAC-IN-50
CAS:<p>HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.</p>Formula:C31H41N7O4Color and Shape:SolidMolecular weight:575.7Mezigdomide
CAS:<p>Mezigdomide (CC-92480) is a potent, novel cereblon E3 ubiquitin ligase modulator (CELMoD) that acts as a molecular glue.Cost-effective and quality-assured.</p>Formula:C32H30FN5O4Purity:97.21% - 99.68%Color and Shape:SolidMolecular weight:567.61TC ASK 10
CAS:<p>TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1,IC50 = 14 nM). The IC50 value for ASK2 is 0.51 μM.</p>Formula:C21H23Cl2N5OPurity:99.86%Color and Shape:SolidMolecular weight:432.35PRMT6-IN-3
CAS:<p>PRMT6-IN-3 is a selective PRMT6 inhibitor with an IC50 value of 192 nM.PRMT6-IN-3 has anticancer activity and induces apoptosis in cancer cells.</p>Formula:C19H26N4O2SPurity:98.12%Color and Shape:SolidMolecular weight:374.5Atiprimod dimaleate
CAS:<p>Atiprimod Dimaleate is a JAK2 inhibitor.</p>Formula:C30H52N2O8Color and Shape:SolidMolecular weight:568.74Topoisomerase II inhibitor 15
CAS:<p>Topoisomerase II inhibitor 15 (compound 2g) serves as a potent apoptotic inducer, exhibiting heightened selectivity for head and neck tumors [1].</p>Formula:C15H11Cl2N5Purity:98%Color and Shape:SolidMolecular weight:332.19
