Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(127 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(90 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Atacicept
CAS:Atacicept (TACI-Ig) is a homodimeric fusion protein that inhibits B cell stimulation.Purity:97.9% (SDS-PAGE); 98.7% (SEC-HPLC) - 97.9% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidMolecular weight:35.36 kDaDAPK-IN-2
CAS:DAPK-IN-2: DAPK inhibitor with anticancer potential. Used in cerebral infarction and ischemia research.Formula:C17H14N2O4Purity:97.36%Color and Shape:SolidMolecular weight:310.3Balstilimab
CAS:Balstilimab (AGEN2034) is a fully human monoclonal IgG4 antibody against PD-1 [1] .Color and Shape:LiquidAnti-Mouse CD44 Antibody (IM7)
Anti-Mouse CD44 Antibody (IM7) is a monoclonal antibody targeting CD44 in mice.Purity:99%Color and Shape:Odour LiquidMolecular weight:150 kDaCIGB-300 acetate
CIGB-300 acetate (P15-Tat acetate) is a peptide that acts as an inhibitor of casein kinase 2 (CK2). It exhibits anticancer properties by disrupting the phosphorylation activity of CK2. CIGB-300 acetate induces apoptosis in various tumor cell lines and is applicable for cancer research.Color and Shape:Odour SolidZeluvalimab
CAS:Zeluvalimab (AMG-404) is a monoclonal antibody designed to target the PD-1 receptor, and is utilized in cancer research [1].Color and Shape:LiquidHexapeptide-11
CAS:Hexapeptide-11 is a novel proteostasis network modulator in human diploid fibroblasts.Formula:C36H48N6O7Purity:98%Color and Shape:SolidMolecular weight:676.8Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl
CAS:Thalidomide 4'-oxyacetamide-alkyl-C2-amine HCl is an E3 ligase ligand-linker conjugate containing the E3 ubiquitin ligase cereblon (CRBN) and linker.Formula:C17H19ClN4O6Purity:99.78%Color and Shape:SolidMolecular weight:410.814-N-Nonyloxyphenol
CAS:4-N-Nonyloxyphenol, kaolinite nanotube photosensitizer, degrades phenolic pesticides, and disrupts endocrine.
Formula:C15H24O2Purity:99.94%Color and Shape:SoildMolecular weight:236.35Finotonlimab
Finotonlimab (SCT-I10A), a humanized IgG PD-1 monoclonal antibody, shows potential in the research of solid tumors or lymphomas [1].Color and Shape:Odour LiquidSotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Purity:98.50% - 98.50%Color and Shape:LiquidMolecular weight:144.35 kDaM24
CAS:M24 inhibits Mcl-1 (Ki = 0.33μM), blocks HepG2 cell growth, and triggers apoptosis.Formula:C44H40Cl3N5O11SColor and Shape:SolidMolecular weight:953.24Ac-AAVALLPAVLLALLAP-YVAD-CHO
CAS:Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1].Formula:C97H160N20O24Purity:98%Color and Shape:SolidMolecular weight:1990.43Destruxin B
CAS:Destruxin B: cyclic peptide from Metarhizium fungus, induces apoptosis in lung cancer via mitochondrial pathway.Formula:C30H51N5O7Purity:98%Color and Shape:SolidMolecular weight:593.766AlbA-DCA
AlbA-DCA, a compound of Albiziabioside A and dichloroacetate, boosts ROS and reduces lactic acid in tumors, killing cancer cells and triggering apoptosis.Formula:C43H67Cl2NO12Purity:98%Color and Shape:SolidMolecular weight:860.9Anti-Mouse PD-1 Antibody (D265A) Antibody (RMP1-14)
Anti-MousePD-1Antibody (D265A) is an antibody inhibitor targeting the PD-1 protein in mice.Color and Shape:Odour LiquidPD0166285 dihydrochloride
CAS:PD-166285 is an effective and broadly active inhibitor of protein tyrosine kinase.Formula:C26H29Cl4N5O2Color and Shape:SolidMolecular weight:585.35EMB-02
EMB-02 is a bispecific antibody targeting both PD-1 and LAG-3. It inhibits the downregulation of T cell activation and proliferation mediated by PD-1 and LAG-3, showing potent anti-cancer properties.Color and Shape:Odour LiquidPROTAC NCOA4 degrader-1
PROTACNCOA4 degrader-1 (Compound V3) is a PROTAC-based degrader of NCOA4, exhibiting a DC50 of 3 nM in HeLa cells. Besides acting as a ferroptosis inhibitor, this compound effectively reduces the levels of NCOA4 and decreases intracellular ferrous (Fe2+) levels. Moreover, PROTACNCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model.Color and Shape:Odour SolidEldecalcitol
CAS:Eldecalcitol, orally active vitamin D analog, boosts bone density and treats osteoporosis.Formula:C30H50O5Purity:98%Color and Shape:SolidMolecular weight:490.72PD-1/PD-L1-IN-48
PD-1/PD-L1-IN-48 (compound HD10) is an effective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 3.1 nM. It plays a vital role in cancer research.Color and Shape:Odour SolidRIPK1-IN-25
RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.Color and Shape:Odour SolidSI-2
CAS:SI-2, a SRC-3 inhibitor, triggers breast cancer cell death (IC50: 3-20 nM), sparing normal cells.Formula:C15H15N5Purity:98.4%Color and Shape:SolidMolecular weight:265.31Ref: TM-T28773
1mg358.00€1mL*10mM (DMSO)800.00€5mg873.00€10mg1,161.00€25mg1,755.00€50mg2,358.00€100mg3,177.00€Ac-DNLD-CHO
CAS:Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, exhibiting IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7Formula:C20H31N5O10Purity:98%Color and Shape:SolidMolecular weight:501.49Oxatomide
CAS:Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).Formula:C27H30N4OPurity:99.28% - 99.72%Color and Shape:White PowderMolecular weight:426.55Ref: TM-T19839
1mg35.00€5mg75.00€1mL*10mM (DMSO)84.00€10mg114.00€25mg222.00€50mg356.00€100mg557.00€500mg1,153.00€3-Methoxy-9H-Carbazole
CAS:3-methoxy-9H-carbazole: photosensitizer, anti-breast cancer, from Klauseneria spp., induces apoptosis.Formula:C13H11NOPurity:99.24%Color and Shape:SolidMolecular weight:197.23Tubulin polymerization-IN-43
CAS:Tubulin polymerization-IN-43 disrupts microtubules, arrests cell cycle, and induces apoptosis in leukemia by targeting colchicine sites.Formula:C17H13F4N3OPurity:99.98%Color and Shape:SoildMolecular weight:351.3BMSpep-57
CAS:BMSpep-57: Macrocyclic peptide, inhibits PD-1/PD-L1, IC50=7.68 nM, binds PD-L1 (Kd=19 nM/MST, 19.88 nM/SPR), boosts T cell IL-2 in PBMCs.Formula:C89H126N24O19SColor and Shape:SolidMolecular weight:1868.2COG-1410 acetate
COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.Formula:C66H125N21O16Purity:99.61%Color and Shape:SolidMolecular weight:1468.83VPC-70063
CAS:VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.Formula:C16H12F6N2SPurity:99.98%Color and Shape:SolidMolecular weight:378.34Ref: TM-T60019
1mg49.00€5mg101.00€1mL*10mM (DMSO)130.00€10mg152.00€25mg268.00€50mg385.00€100mg560.00€200mg790.00€Ac-AAVALLPAVLLALLAP-LEHD-CHO
CAS:Ac-AAVALLPAVLLALLAP-LEHD-CHO is a caspase inhibitor targeting caspases 4, 5, and 9, demonstrating protective effects in MCF-7 cells treated withFormula:C97H162N22O25Purity:98%Color and Shape:SolidMolecular weight:2036.46HKB99
CAS:HKB99 suppresses NSCLC growth, metastasis, and overcomes erlotinib resistance.Formula:C23H18N2O6SPurity:97.35% - 97.35%Color and Shape:SolidMolecular weight:450.46Ac-AAVALLPAVLLALLAP-LEVD-CHO
CAS:Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable inhibitor of caspase-4 that exhibits antitumor activity [1].Formula:C96H164N20O25Purity:98%Color and Shape:SolidMolecular weight:1998.45YL-5092
CAS:YL-5092, YTHDC1 inhibitor (IC50=7.4 nM), induces G0/G1 arrest and apoptosis, used for acute myeloid leukemia (AML).Formula:C22H14F3N3O2SColor and Shape:SolidMolecular weight:441.43YL5084
CAS:YL5084 is a selective JNK2/3 inhibitor with IC50s: JNK2 (70 nM), JNK3 (84 nM), and antiproliferative, apoptosis-inducing effects.Formula:C35H36N8O2Color and Shape:SolidMolecular weight:600.71NLRP3-IN-55
NLRP3-IN-55 (Compound 19) is an effective inhibitor of NLRP3, exhibiting an inhibitory concentration (IC50) of 0.34 μM. It targets the NLRP3 protein directly with a dissociation constant (KD) of 0.45 μM, effectively blocking the assembly and activation of the NLRP3 inflammasome. This action results in anti-inflammatory effects and inhibits cell pyroptosis.Formula:C32H30ClFN2O4Color and Shape:SolidMolecular weight:561.04SM-164 Hydrochloride
SM-164 Hydrochloride: Smac mimetic, cell-permeable, binds XIAP BIR2 and BIR3, IC50 of 1.39 nM, potent XIAP antagonist.Formula:C62H85ClN14O6Color and Shape:SolidMolecular weight:1157.88Ac-FEID-CMK TFA
Ac-FEID-CMK TFA is a zebrafish GSDMEb-derived peptide inhibitor that acts by inhibiting the caspy2-mediated atypical inflammatory vesicle pathway.Formula:C29H38ClF3N4O11Purity:95%Color and Shape:SolidMolecular weight:711.08PROTAC PD-1/PD-L1 degrader-1
CAS:PROTAC PD-1/PD-L1 degrader-1, a Cereblon-based inhibitor, blocks PD-1/PD-L1 with 39.2 nM IC50, boosting immune response and reducing PD-L1 via lysosomes.Formula:C59H58ClN7O11Purity:99.07%Color and Shape:SolidMolecular weight:1076.59SRE-II
SRE-II, an amide derivative, serves as an activatable photosensitizer tailored for photodynamic cancer research, exhibiting diminished fluorescence andFormula:C15H9ClINO2Purity:98%Color and Shape:SolidMolecular weight:397.59dFKBP-1
CAS:dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].Formula:C53H64N6O14Purity:98%Color and Shape:SolidMolecular weight:1009.11Ono 3403
CAS:Ono 3403, a synthetic serine protease inhibitor, blocks TNF-alpha, NO production, and has antitumor properties.Formula:C26H31N3O8SPurity:98%Color and Shape:SolidMolecular weight:545.6IETD-CHO TFA
IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1].Formula:C95H162N20O26·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:2000.42 (free acid)YT117R
YT117R is a PROTAC that targets degradation of FKBP12 and BRD4.Formula:C50H52ClN9O7SColor and Shape:SolidMolecular weight:958.52NOD1/2-IN-1
NOD1/2-IN-1 (Compound 18) is a potent RIPK2 inhibitor, demonstrating an IC50 value of 1.4 nM in the ADP-Glo assay. It blocks the production of pro-inflammatory cytokines by inhibiting the NOD1/NOD2 pathway (IC50 values are 18 nM and 170 nM for NOD1 and NOD2, respectively), thereby reducing inflammatory responses. This compound is utilized in research related to colitis.Color and Shape:Odour Solid2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc
2-Methylbiphenyl-oxadiazole-NH-Ph-NH-PEG3-C2-NH-Boc is the PD-L1 ligand-linker polymer of AUTACPD-L1degrader-3. It can be utilized in the synthesis of AUTAC.Formula:C35H45N5O6Color and Shape:SolidMolecular weight:631.76LTB
LTB is a prodrug formed through the conjugation of the glycolysis inhibitor (Lonidamine) and the PD1/PDL1 blocker (BMS-1) via a thioketal bond. LTB can encapsulate the photosensitizer Chlorin e6 (Ce6), constructing a co-delivery photodynamic nanoplatfform through self-assembly (LTB-6 NPs).Formula:C53H59Cl2N3O7S2Color and Shape:SolidMolecular weight:985.09Compound TPX-0046
CAS:Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.Formula:C21H21FN6O3Purity:99.94%Color and Shape:SoildMolecular weight:424.43SLF-amido-C2-COOH
CAS:SLF-amido-C2-COOH is a synthetic ligand for FKBP (SLF), and can be used in the synthesis of PROTACs.Formula:C34H44N2O9Purity:95.8%Color and Shape:SolidMolecular weight:624.72PD-1/PD-L1 inhibitory peptide C8
PD-1/PD-L1 inhibitory peptide C8 disrupts the PD-1/PD-L1 interaction, leading to the activation of CD8+ and CD4+ T cells and an increase in IFN-γ secretion. In mouse models, PD-1/PD-L1 inhibitory peptide C8 has demonstrated antitumor activity.Formula:C51H72N14O14S2Color and Shape:SolidMolecular weight:1169.33
