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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

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Found 6170 products of "Apoptosis"

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  • WK369


    WK369 is an innovative small molecule inhibitor of BCL6, demonstrating remarkable bioactivity against ovarian cancer by inducing cell cycle arrest and triggering apoptosis. It binds directly to the BCL6-BTB domain, obstructing the interaction between BCL6 and SMRT, which results in the reactivation of p53, ATR, and CDKN1A.
    Formula:C19H20FN5O2
    Molecular weight:369.1601

    Ref: TM-T209047

    10mg
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    50mg
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  • NAE-IN-1


    NAE-IN-1 (compound X-10) is a potent inhibitor of NAE1. It induces apoptosis and causes cell cycle arrest in the G2/M phase. Furthermore, NAE-IN-1 increases ROS levels and inhibits cell migration, demonstrating antiproliferative activity.
    Formula:C29H30N4O2S
    Molecular weight:498.20895

    Ref: TM-T209353

    10mg
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    50mg
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  • RIPK1-IN-22


    RIPK1-IN-13 (compound 28) is a selective inhibitor of receptor-interacting serine/threonine-protein kinase 1 (RIPK1), showing a pKi of 7.66 as measured by the ADP-Glo kinase assay. It exhibits inhibitory effects in human leukemia U937 cells with a pIC50 of 7.2.
    Formula:C22H22N4O3S
    Molecular weight:422.14126

    Ref: TM-T209395

    10mg
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    50mg
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  • 155H1


    155H1 (Compound 11) is a stapled peptide that covalently binds to hMcl1 (172-323) with an IC50 of 18 nM.
    Formula:C79H120FN19O23S
    Molecular weight:1753.85092

    Ref: TM-TP3562

    10mg
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    50mg
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  • WEE1-IN-7


    WEE1-IN-7 (compound 12h) is a potent, orally active WEE1 inhibitor with an IC50 value of 2.1 nM. This compound induces apoptosis and causes cell cycle arrest in the S phase, demonstrating antitumor activity.

    Ref: TM-T210408

    10mg
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    50mg
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  • RIP1 kinase inhibitor 9


    RIP1 kinase inhibitor 9 (compound SY-1) is a selective inhibitor of RIP kinase. It effectively reduces central inflammatory responses caused by seizures. RIP1 kinase inhibitor 9 also obstructs Z-VAD-FMK-induced necroptosis in HT-29 cells, with an EC50 of 7.04 nM.
    Formula:C25H21N3O3
    Molecular weight:411.15829

    Ref: TM-T209274

    10mg
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    50mg
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  • PROTAC PD-L1 degrader-1


    PROTACPD-L1 degrader-1 is a CRBN-based PD-L1-PROTAC degrader with significant PD-L1 protein degradation capacity. It demonstrates strong PD-L1 degradation activity in 4T1 cells, with a DC50 of 0.609 μM. This compound is applicable to breast cancer research.

    Ref: TM-T210164

    10mg
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    50mg
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  • ECDD-S16


    ECDD-S16 is a potent inhibitor of pyroptosis. It effectively suppresses pyroptosis in Raw264.7 cells activated by surface and endosomal TLR ligands.
    Formula:C35H31FO12
    Molecular weight:662.17995

    Ref: TM-T208793

    10mg
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    50mg
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  • Anticancer agent 204


    Anticanceragent 204 (Compound 6) is a fluorinated derivative of cinnamamides with anticancer activity. It can arrest the cell cycle of HepG2 cells in the G1 phase and induces apoptosis by reducing mitochondrial membrane polarization (MMP) levels.
    Formula:C26H18FN5O3S
    Molecular weight:499.11144

    Ref: TM-T209605

    10mg
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    50mg
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  • Necrosis inhibitor 2 (hydrocholide)


    Necrosis inhibitor 2 hydrochloride (Compound B19) is an agent that inhibits cellular necrosis. It is useful for researching diseases associated with necrotic pathways, including inflammation, cancer, metabolic disorders, and neurodegenerative diseases.
    Formula:C24H26ClN5O5
    Molecular weight:499.16225

    Ref: TM-T208775

    10mg
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    50mg
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  • EGFR-PK/JNK-2-IN-1


    EGFR-PK/JNK-2-IN-1 (Compound 6c) is a dual inhibitor of EGFR-PK and JNK-2, with IC50 values of 2.7 and 3.0 μM, respectively. It can induce apoptosis and cause cell cycle arrest at various stages. This compound is applicable in cancer research.
    Formula:C22H17ClN4O3S
    Molecular weight:452.07099

    Ref: TM-T209433

    10mg
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    50mg
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  • Thalidomide-N-C3-O-C4-O-C3-OH


    Thalidomide-N-C3-O-C4-O-C3-OH is a conjugate of an E3 ligase ligand and a linker, used in the synthesis of the Aster-APROTAC degrader.
    Formula:C23H31N3O7
    Molecular weight:461.2162

    Ref: TM-T210110

    10mg
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    50mg
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  • HDAC6-IN-28


    HDAC6-IN-28 (compound 10C) is a potent inhibitor of HDAC6 with an IC50 of 261 nM. It significantly induces apoptosis in B16-F10 cells and causes S phase arrest. Additionally, HDAC6-IN-28 effectively increases the expression of acetylated-α-tubulin both in vitro and in vivo.
    Formula:C23H16FN3O2
    Molecular weight:385.12265

    Ref: TM-T208751

    10mg
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    50mg
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  • LC-1-40


    LC-1-40 is a PROTAC that selectively degrades NUDT1 (DC50=0.97 nM). In mouse models, LC-1-40 selectively inhibits tumor growth induced by MYCN and induces nucleotide damage and apoptosis (cell death) in MYCN-associated tumors. It is applicable for cancer research.
    Formula:C49H48N8O6
    Molecular weight:844.36968

    Ref: TM-T209447

    10mg
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    50mg
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  • Chlopynostat


    Chlopynostat (Compound 6c) is an HDAC1 inhibitor with an IC50 value of 67 nM. It induces apoptosis by inhibiting HDAC1, thereby reversing STAT4/p66Shc defects.
    Formula:C22H17ClN4O2
    Molecular weight:404.104

    Ref: TM-T209732

    10mg
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    50mg
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  • RIPK2-IN-4


    RIPK2-IN-4 is a potent and specific inhibitor of RIPK2 with an IC50 value of 5 nM.
    Formula:C16H10N6S2
    Molecular weight:350.04084

    Ref: TM-T208744

    10mg
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    50mg
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  • Thalidomide-NH-amido-C6-NH2 hydrochloride


    Thalidomide-NH-amido-C6-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate that includes a thalidomide-based cereblon ligand and a linker, designed for the synthesis of PROTAC.
    Formula:C21H28ClN5O5
    Molecular weight:465.1779

    Ref: TM-T208135

    10mg
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    50mg
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  • Camrelizumab

    CAS:

    Camrelizumab (SHR-1210) is a human IgG4-κ monoclonal antibody with high affinity and directed against PD-1.Camrelizumab binds PD-1 with a binding affinity of up

    Purity:95% - 98.6%
    Color and Shape:Liquid
    Molecular weight:143.7 kDa

    Ref: TM-T37535

    1mg
    160.00€
    5mg
    547.00€
    10mg
    782.00€
    25mg
    1,159.00€
  • Lw13


    Lw13 is a PROTAC targeting Hsp90, exhibiting maximal degradation efficacy at a concentration of 0.05 μM in Siha cells. Lw13 induces apoptosis and demonstrates potent antitumor activity both in vitro and in vivo.
    Formula:C46H55F3N8O8
    Molecular weight:904.4095

    Ref: TM-T210047

    10mg
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    50mg
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  • SB 699551

    CAS:
    SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.
    Formula:C34H45N3O
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:511.74

    Ref: TM-T23325L

    1mg
    190.00€
    5mg
    471.00€
    10mg
    662.00€
    25mg
    1,036.00€
    50mg
    1,429.00€
    100mg
    1,821.00€
    200mg
    2,489.00€
  • Feladilimab

    CAS:

    Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist.

    Purity:SDS-PAGE:95% SEC-HPLC:98%
    Color and Shape:Liquid
    Molecular weight:145.24 kDa

    Ref: TM-T77433

    1mg
    187.00€
    5mg
    512.00€
    10mg
    787.00€
    25mg
    1,169.00€
    50mg
    1,568.00€
  • Pacmilimab

    CAS:
    Pacmilimab (CX-072) is a Probody immune checkpoint inhibitor targeting programmed death ligand 1 (PD-L1) with anti-tumor activity for the study of solid tumors.
    Purity:98.8% (SDS-PAGE); 96.3% (SEC-HPLC) - 98.8% (SDS-PAGE); 96.3% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:153.3 kDa

    Ref: TM-T77128

    1mg
    158.00€
    5mg
    404.00€
    10mg
    643.00€
    25mg
    973.00€
    50mg
    1,314.00€
  • Poly (I:C):Kanamycin (1:1)


    Poly (I:C):Kanamycin (1:1) is an equimolar mixture of Poly(I:C) and kanamycin. TLR3 agonist commonly used as a vaccine adjuvant; enhanced Poly(I:C) stability.

    Color and Shape:Solid

    Ref: TM-T73674

    2mg
    38.00€
    5mg
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    25mg
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  • WF 10129

    CAS:
    WF 10129 is a new angiotensin converting enzyme inhibitor generated by a fungus, Doratomyces putredinis.
    Formula:C20H28N2O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:424.45

    Ref: TM-T26329

    25mg
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  • C188

    CAS:
    C188, a naphthol-based STAT3 inhibitor, blocks IL-6-induced STAT3 activity in HepG2 cells, sparing STAT1.
    Formula:C19H15NO7S2
    Color and Shape:Solid
    Molecular weight:433.45

    Ref: TM-T26936

    10mg
    197.00€
  • MBC-11 triethylamine


    MBC-11 triethylamine, a first-in-class etidronate-araC conjugate, may treat TIBD.
    Formula:C17H35N4O14P3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:612.4

    Ref: TM-T11956

    25mg
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  • Ro 48-8071

    CAS:
    Oxidosqualene cyclase inhibitor
    Formula:C23H27BrFNO2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:448.37

    Ref: TM-T22629

    5mg
    132.00€
    10mg
    254.00€
    50mg
    1,018.00€
    100mg
    1,783.00€
  • Solanidine

    CAS:
    Solanidine is a cholestane alkaloid isolated from potato species with antitumor effects. Solanidine inhibits proliferation.
    Formula:C27H43NO
    Purity:96.83%
    Color and Shape:Solid
    Molecular weight:397.64

    Ref: TM-T12971

    1mg
    93.00€
    5mg
    260.00€
    10mg
    447.00€
    25mg
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    50mg
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  • BKM1644

    CAS:
    BKM1644 is an effective inhibition of the proliferation of metastatic, castration-resistant PCa (mCRPC) cells.
    Formula:C34H37Cl2F5N2O9P2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:845.51

    Ref: TM-T26831

    25mg
    1,369.00€
  • Antitumor photosensitizer-7


    Antitumor photosensitizer-7 (compound 15), a photosensitizer possessing anti-cancer properties, demonstrates substantial cytotoxic effects on the G361 melanoma cell line when exposed to 414 nm blue light irradiation.
    Formula:C23H20N2O3
    Color and Shape:Solid
    Molecular weight:372.42

    Ref: TM-T200006

    10mg
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  • Linsidomine hydrochloride

    CAS:
    SIN-1 chloride is a moxidomine metabolite with vasodilatory, anti-platelet, and antianginal effects, reducing myocardial ischemia-related damage.
    Formula:C6H11ClN4O2
    Purity:99.27% - 99.67%
    Color and Shape:White Solid Crystalline
    Molecular weight:206.63

    Ref: TM-T23356

    2mg
    34.00€
    5mg
    50.00€
    10mg
    84.00€
    25mg
    145.00€
    50mg
    To inquire
    1mL*10mM (DMSO)
    56.00€
  • Isorhamnetin 3-glucuronide


    Isorhamnetin 3-glucuronide is a useful organic compound for research related to life sciences and the catalog number is T124938.
    Formula:C22H20O13
    Color and Shape:Solid
    Molecular weight:492.389

    Ref: TM-T124938

    1mg
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    5mg
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  • 2-Chloronaphthalene

    CAS:
    2-Chloronaphthalene is an organochlorine chemical compound and is a chlorinated derivative of naphthalene. The compound is an isomer for 1-chloronaphthalene.
    Formula:C10H7Cl
    Purity:98%
    Color and Shape:Solid
    Molecular weight:162.62

    Ref: TM-T20317

    1g
    188.00€
  • Lambertianic acid

    CAS:
    Lambertianic acid is a bioactive chemical that has anti-allergic and antibacterial effects.
    Formula:C20H28O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:316.441

    Ref: TM-T25605

    25mg
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  • Fludioxonil

    CAS:
    Fludioxonil (CGA 173506), a phenylpyrrole fungicide, inhibits the growth of B. cinerea from strawberry and blackberry crops.
    Formula:C12H6F2N2O2
    Purity:99.971%
    Color and Shape:Solid
    Molecular weight:248.18

    Ref: TM-T20905

    25mg
    43.00€
    50mg
    57.00€
    100mg
    80.00€
    500mg
    173.00€
  • Aspochalasin D

    CAS:

    Aspochalasin D, isolated from A. microcysticus, shows antibacterial properties and cytotoxicity affecting Ba/F3-V12 cells, with IC50s of 0.49 and 1.9 μg/ml.

    Formula:C24H35NO4
    Color and Shape:Solid
    Molecular weight:401.54

    Ref: TM-T37443

    1mg
    217.00€
    5mg
    882.00€
  • Linearol

    CAS:
    Linearol: diterpene from Sideritis L. with antioxidant, anti-inflammatory, anti-apoptotic effects.
    Formula:C22H34O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:362.50

    Ref: TM-T25735

    25mg
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  • spisulosine

    CAS:

    spisulosine is a natural product for research related to life sciences. The catalog number is T9664 and the CAS number is 196497-48-0.

    Formula:C18H39NO
    Color and Shape:Solid
    Molecular weight:285.516

    Ref: TM-T9664

    5mg
    1,786.00€
    10mg
    3,163.00€
  • 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE

    CAS:

    Phospholipid with stearic acid and 15(S)-HpETE boosts ferroptosis in MEFs upon GPX4 inhibition.

    Formula:C43H78NO10P
    Color and Shape:Solid
    Molecular weight:800.068

    Ref: TM-T37487

    50µg
    401.00€
    100µg
    748.00€
  • Albicanol

    CAS:
    Albicanol is a biochemical.
    Formula:C15H26O
    Color and Shape:Solid
    Molecular weight:222.372

    Ref: TM-T29832

    25mg
    To inquire
  • Ceftiofur hydrochloride

    CAS:
    Ceftiofur hydrochloride (U-67279A) is a stable, broad-spectrum 3rd-gen cephalosporin with antibacterial properties.
    Formula:C19H17N5O7S3·HCl
    Purity:99.51%
    Color and Shape:Off-White Solid
    Molecular weight:560.02

    Ref: TM-T6268

    1g
    57.00€
    500mg
    44.00€
    1mL*10mM (DMSO)
    34.00€
  • NQO2-IN-1

    CAS:
    NQO2-IN-1, a resveratrol analog, is a potent NQO2 inhibito,antitumor,generation of ROS and up-regulation of DR5 (death receptor 5) to promote apoptosis.
    Formula:C18H18N2O3
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:310.35

    Ref: TM-T203013

    1mg
    128.00€
    5mg
    305.00€
    10mg
    444.00€
    25mg
    686.00€
    50mg
    947.00€
    100mg
    1,180.00€
    200mg
    1,602.00€
  • RET-IN-28

    CAS:
    RET-IN-28 (Compound 16) is an inhibitor of RET (a transmembrane receptor tyrosine kinase). It specifically inhibits the activity of a mutant RET enzyme (RET-V804M) and is utilized in cancer research.
    Formula:C26H29N9
    Color and Shape:Solid
    Molecular weight:467.57

    Ref: TM-T203439

    10mg
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  • Azadirone

    CAS:

    Azadirone, a limonoid, sensitizes cancer cells to TRAIL by modulating DR4/DR5, survival, and apoptotic proteins.

    Formula:C9H15N3O5
    Color and Shape:Solid
    Molecular weight:245.23

    Ref: TM-T26709

    25mg
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    50mg
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    100mg
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  • Resolvin D2 n-3 DPA

    CAS:

    RvD2 n-3 DPA is an SPM made from docosapentaenoic acid in human leukocytes, inhibiting neutrophil chemotaxis and adhesion.

    Formula:C22H34O5
    Color and Shape:Solid
    Molecular weight:378.509

    Ref: TM-T37289

    10µg
    527.00€
    25µg
    1,216.00€
    50µg
    2,347.00€
    100µg
    4,114.00€
  • Vonlerolizumab

    CAS:
    Vonlerolizumab (MOXR 0916) is a humanized IgG OX40 agonist monoclonal antibody with potential in cancer and immune disease research.
    Purity:SDS-PAGE:97.3%;SEC-HPLC:99.4%
    Color and Shape:Liquid
    Molecular weight:145.25 kDa

    Ref: TM-T9901A-006

    1mg
    315.00€
    5mg
    820.00€
  • Conophylline

    CAS:
    Conophylline, an alkaloid from Ervatamia microphylla, induces pancreatic cell differentiation and apoptosis, and suppresses HSC.
    Formula:C44H50N4O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:794.89

    Ref: TM-T13624

    5mg
    1,521.00€
  • (R)-JAK2/STAT3-IN-10a

    CAS:

    (R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a structural domain inhibitor of GP130 D1 with antitumor activity.

    Formula:C34H35BrF3N5O2
    Purity:97.99%
    Color and Shape:Soild
    Molecular weight:682.57

    Ref: TM-T72754L

    1mg
    185.00€
    5mg
    459.00€
    10mg
    657.00€
    25mg
    1,026.00€
    50mg
    1,415.00€
    100mg
    1,872.00€
  • WKYMVM

    CAS:
    WKYMVM is a N-formyl peptide receptor (FPR1) agonist.
    Formula:C41H61N9O7S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:856.11

    Ref: TM-T7484

    1mg
    645.00€
  • Ac-IEPD-AFC

    CAS:
    Ac-IEPD-AFC (IEPD) is a fluorescent substrate for granzyme B and can be used to measure granzyme B activity.
    Formula:C32H38F3N5O11
    Purity:99.16%
    Color and Shape:Solid
    Molecular weight:725.67

    Ref: TM-TP1128

    1mg
    49.00€
    5mg
    93.00€
    10mg
    137.00€
    25mg
    224.00€
    50mg
    331.00€
    100mg
    489.00€