Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5598 products of "Apoptosis"
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Osthole
CAS:<p>Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.</p>Formula:C15H16O3Purity:99.93% - 99.96%Color and Shape:Fine White PowderMolecular weight:244.29Arctigenin
CAS:<p>(-)-Arctigenin ((-)-Arctigenin) is found in burdock.</p>Formula:C21H24O6Purity:98% - 99.51%Color and Shape:SolidMolecular weight:372.41Necrostatin-1
CAS:<p>Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.</p>Formula:C13H13N3OSPurity:99.25% - >99.99%Color and Shape:SolidMolecular weight:259.33R547
CAS:<p>R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.</p>Formula:C18H21F2N5O4SPurity:90% - 99.64%Color and Shape:SolidMolecular weight:441.45Pyraclostrobin
CAS:<p>Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.</p>Formula:C19H18ClN3O4Purity:99.89%Color and Shape:SolidMolecular weight:387.82CCT007093
CAS:<p>CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).</p>Formula:C15H12OS2Purity:98% - 99.88%Color and Shape:SolidMolecular weight:272.39PHT-427
CAS:<p>PHT-427 (CS-0223) is a dual Akt (Ki: 2.7 μM) and PDPK1 (Ki: 5.2 μM) inhibitor (high-affinity binding for the PH domains of Akt and PDPK1).</p>Formula:C20H31N3O2S2Purity:97.54% - >99.99%Color and Shape:SolidMolecular weight:409.61NPS-1034
CAS:<p>NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.</p>Formula:C31H23F2N5O3Purity:98.48%Color and Shape:SolidMolecular weight:551.54Bafetinib
CAS:<p>Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.</p>Formula:C30H31F3N8OPurity:94.16% - 99.68%Color and Shape:SolidMolecular weight:576.62NVP-CGM097
CAS:<p>NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).</p>Formula:C38H47ClN4O4Purity:98.77%Color and Shape:SolidMolecular weight:659.26Telekin
CAS:<p>Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.</p>Formula:C15H20O3Purity:99.86% - 99.97%Color and Shape:SolidMolecular weight:248.32L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Formula:C5H9NO4Purity:99.14% - 99.55%Color and Shape:White Solid CrystallineMolecular weight:147.13Sirtinol
CAS:<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formula:C26H22N2O2Purity:97.12% - 99.96%Color and Shape:SolidMolecular weight:394.47API-1
CAS:<p>API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .</p>Formula:C13H15N5O6Purity:97.15%Color and Shape:SolidMolecular weight:337.29AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43Atractylenolide II
CAS:<p>Atractylenolide II inhibits STAT3, activates p38, deactivates ERK/Akt, and induces p53-dependent cytotoxicity against melanoma.</p>Formula:C15H20O2Purity:99.89% - 99.93%Color and Shape:SolidMolecular weight:232.32RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Formula:C24H16F6N6OPurity:99.56%Color and Shape:SolidMolecular weight:518.41Epieriocalyxin A
CAS:<p>Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.</p>Formula:C20H24O5Purity:97.00%Color and Shape:SolidMolecular weight:344.4Helichrysetin
CAS:<p>Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.</p>Formula:C16H14O5Purity:96.32% - ≥95%Color and Shape:SolidMolecular weight:286.28Ligustrazine
CAS:<p>Ligustrazine (Tetramethylpyrazine), a natural compound isolated from Chuan Xiong shows anti-inflammation, antioxidant, antiplatelet, and antiapoptosis effects.</p>Formula:C8H12N2Purity:99.91% - >99.99%Color and Shape:White Crystals Or PowderMolecular weight:136.19Didymin
CAS:<p>Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.</p>Formula:C28H34O14Purity:99.12% - 99.87%Color and Shape:Faintly Beige PowderMolecular weight:594.563,6-Dihydroxyflavone
CAS:<p>3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.</p>Formula:C15H10O4Purity:99.92%Color and Shape:SolidMolecular weight:254.24Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Formula:C40H54N4O10SPurity:99.85%Color and Shape:White To Light Yellow Crystal PowdeMolecular weight:782.9Nystatin
CAS:<p>Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat</p>Formula:C47H75NO17Purity:69.55% - 99.53%Color and Shape:Yellow SuspensionMolecular weight:926.1CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Formula:C34H43N3O3Purity:98.3% - 99.61%Color and Shape:SolidMolecular weight:541.72KEA1-97
CAS:<p>Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).</p>Formula:C15H9Cl2FN4Purity:97.07%Color and Shape:SolidMolecular weight:335.16Pralatrexate
CAS:<p>Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate</p>Formula:C23H23N7O5Purity:94.32% - 99.59%Color and Shape:SolidMolecular weight:477.47Vatalanib dihydrochloride
CAS:<p>Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.</p>Formula:C20H15ClN4·2HClPurity:99.16%Color and Shape:White To Off-White Crystalline PowderMolecular weight:419.73ML385
CAS:<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Formula:C29H25N3O4SPurity:98.08% - >99.99%Color and Shape:SolidMolecular weight:511.59XL019
CAS:<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Formula:C25H28N6O2Purity:99.19%Color and Shape:SolidMolecular weight:444.53tubuloside B
CAS:<p>Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.</p>Formula:C31H38O16Purity:97.59% - 99.72%Color and Shape:SolidMolecular weight:666.62ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Formula:C42H45ClN6O5S2Purity:98.15% - >99.99%Color and Shape:SolidMolecular weight:813.43JX06
CAS:<p>JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.</p>Formula:C10H16N2O2S4Purity:99.4%Color and Shape:SolidMolecular weight:324.51MK-2206 dihydrochloride
CAS:<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Formula:C25H23Cl2N5OPurity:99.228% - 99.94%Color and Shape:SolidMolecular weight:480.39Geranyl acetate
CAS:<p>Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.</p>Formula:C12H20O2Purity:98% - 99.36%Color and Shape:Physical Description Clear Colorless Liquid With An Odor Of Lavender (Ntp 1992)Molecular weight:196.295'-Methylthioadenosine
CAS:<p>5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.</p>Formula:C11H15N5O3SPurity:99.32% - 99.34%Color and Shape:SolidMolecular weight:297.33Stattic
CAS:<p>Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.</p>Formula:C8H5NO4SPurity:98.32% - 99.76%Color and Shape:SolidMolecular weight:211.19Rasagiline Mesylate
CAS:<p>Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.</p>Formula:C13H17NO3SPurity:99.33%Color and Shape:White PowderMolecular weight:267.34DL-Buthionine-(S,R)-sulfoximine
CAS:<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Formula:C8H18N2O3SPurity:98% - 99.64%Color and Shape:White Fine PowderMolecular weight:222.31AT7519 Hydrochloride
CAS:<p>AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.</p>Formula:C16H18Cl3N5O2Purity:99.66% - 99.9%Color and Shape:SolidMolecular weight:418.71Gefitinib dihydrochloride
CAS:<p>Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.</p>Formula:C22H26Cl3FN4O3Color and Shape:SolidMolecular weight:519.82Aurintricarboxylic acid
CAS:<p>Aurintricarboxylic acid (NSC-4056) blocks nucleases and topoisomerases, stopping nucleic acid binding.</p>Formula:C22H14O9Purity:97.1%Color and Shape:Deep Red Coarse Crystalline PowderMolecular weight:422.34Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35Tamibarotene
CAS:<p>Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic</p>Formula:C22H25NO3Purity:98.55% - 99.73%Color and Shape:Crystalline SolidMolecular weight:351.44Piperlongumine
CAS:<p>Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.</p>Formula:C17H19NO5Purity:97.03% - 99.90%Color and Shape:SolidMolecular weight:317.34Polydatin
CAS:<p>Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.</p>Formula:C20H22O8Purity:97.2% - 98.94%Color and Shape:White Fine PowderMolecular weight:390.38Sclareol
CAS:<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Formula:C20H36O2Purity:99.58% - 99.97%Color and Shape:White Fine PowderMolecular weight:308.5SC-43
CAS:<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Formula:C21H13ClF3N3O2Purity:98.44%Color and Shape:SolidMolecular weight:431.8TW-37
CAS:<p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>Formula:C33H35NO6SPurity:97.06% - ≥95%Color and Shape:SolidMolecular weight:573.7Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Formula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47
