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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

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Found 6170 products of "Apoptosis"

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  • Osajin

    CAS:
    Osajin is the major bioactive iso avone present in the fruit of Maclura pomifera. It has antitumor, antioxidant, and anti-inflammatory activities.
    Formula:C25H24O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:404.46

    Ref: TM-T16407

    5mg
    617.00€
  • Targaprimir-96

    CAS:
    Targaprimir-96 is a potent microRNA-96 (miR-96) processing inhibitor.
    Formula:C77H102N18O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1391.75

    Ref: TM-T13085

    25mg
    1,369.00€
  • HLDA-212

    CAS:
    HLDA-212 (Compound 43) is a bifunctional small molecule designed to target HaloTag-tagged protein (target protein, TP) and Aurora kinase A/B (AURKA/B, effector protein, EP). By binding TP and EP, it forms a stable ternary complex (TP:RIPTAC:EP) that inhibits the cell survival functions of EP, inducing apoptosis in cancer cells expressing TP. In 293_HFL cells, HLDA-212 demonstrates antiproliferative activity with a GI50 of 0.011 μM. This compound holds promise for treating cancers with high TP expression, such as prostate cancer and hematological malignancies.
    Formula:C70H90BrFN8O19S
    Color and Shape:Solid
    Molecular weight:1478.47

    Ref: TM-T207415

    10mg
    To inquire
    50mg
    To inquire
  • CTP-347

    CAS:
    CTP-347, a deuterated version of paroxetine, is potentially the best non-hormonal drug in its class for the treatment of hot flashes.
    Formula:C19H20FNO3
    Color and Shape:Solid
    Molecular weight:331.38

    Ref: TM-T31108

    100mg
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    500mg
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  • ATWLPPRAANLLMAAS

    CAS:
    ATWLPPRAANLLMAAS is a chimeric peptide with anti-angiogenic and potent antitumor capabilities. It effectively inhibits the proliferation, viability, migration, and invasion of human hepatocellular carcinoma cells, and induces apoptosis (apoptosis).
    Formula:C76H123N21O20S
    Molecular weight:1682.98

    Ref: TM-TP2993

    10mg
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    50mg
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  • Thalidomide-O-amido-PEG3-C2-NH2

    CAS:
    Thalidomide-O-amido-PEG3-C2-NH2 is a cereblon ligand-linker for PROTACs with a 3-unit PEG.
    Formula:C23H30N4O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.51

    Ref: TM-T17915

    100mg
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    500mg
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  • Ecdysone

    CAS:
    Ecdysone is a major steroid hormone in insects and herbs.
    Formula:C27H44O6
    Purity:99.22%
    Color and Shape:Powder
    Molecular weight:464.63

    Ref: TM-TN3910

    1mg
    96.00€
    5mg
    289.00€
    10mg
    421.00€
    25mg
    675.00€
    50mg
    928.00€
    100mg
    1,251.00€
    200mg
    1,693.00€
  • β-Amyloid (1-40) (rat)

    CAS:
    Rat form of the beta-Amyloid (1-40) peptide
    Formula:C190H291N51O57S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:4233.76

    Ref: TM-TP1441

    1mg
    150.00€
  • Spexin

    CAS:
    Potent GAL2/GAL3 agonist (EC50 = 45.7, 112.2 nM), inactive at GAL1. Reduces appetite, fatty acid uptake in adipocytes, and LH in goldfish; anxiolytic in vivo.
    Formula:C74H114N20O19S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1619.9

    Ref: TM-TP1930

    1mg
    888.00€
  • Z-DQMD-FMK

    CAS:

    Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.

    Formula:C29H40FN5O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:685.72

    Ref: TM-TP2037

    1mg
    309.00€
  • ZZM-1220


    ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.
    Formula:C25H29N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:447.53

    Ref: TM-T79776

    5mg
    To inquire
    50mg
    To inquire
  • Fuscin

    CAS:
    Fuscin, a quinonoid from O. fuscum, inhibits ADP/ATP translocase, depletes glutathione, disrupts NADH oxidation, and blocks MIP-1α/CCR5 binding (IC50: 21µM).
    Formula:C15H16O5
    Color and Shape:Solid
    Molecular weight:276.288

    Ref: TM-T37714

    5mg
    2,025.00€
  • Chloranil

    CAS:
    Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in mice.
    Formula:C6Cl4O2
    Purity:98.03%
    Color and Shape:Solid
    Molecular weight:245.88

    Ref: TM-T80673

    1g
    33.00€
  • KWCN-41

    CAS:
    KWCN-41, Selective RIPK1 inhibitor (IC50=88 nM), inhibits necrosis specifically, anti-inflammatory effects.
    Formula:C18H17N3O2
    Color and Shape:Solid
    Molecular weight:307.35

    Ref: TM-T74801

    1mg
    161.00€
    5mg
    389.00€
  • DC-Y13-27


    Dc-y13-27, a derivative of DC-Y13, is a potent YTHDF2 inhibitor (KD: 37.9 μM).

    Formula:C14H10N2O2S
    Purity:99.75%
    Color and Shape:Soild
    Molecular weight:270.31

    Ref: TM-T77764

    2mg
    35.00€
    5mg
    52.00€
    10mg
    88.00€
    25mg
    160.00€
    50mg
    235.00€
    100mg
    354.00€
    1mL*10mM (DMSO)
    58.00€
  • AVJ16

    CAS:
    AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.
    Formula:C28H27N3O4
    Purity:98.87% - 99.72%
    Color and Shape:Solid
    Molecular weight:469.53

    Ref: TM-T9980

    1mg
    130.00€
    5mg
    313.00€
    10mg
    500.00€
    25mg
    807.00€
    50mg
    1,108.00€
    100mg
    1,485.00€
    200mg
    1,998.00€
    1mL*10mM (DMSO)
    323.00€
  • PROTAC Bcl2 degrader-1

    CAS:
    PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).
    Formula:C45H45BrN6O10S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:941.84

    Ref: TM-T10485

    1mg
    1,080.00€
    5mg
    2,340.00€
    10mg
    To inquire
    50mg
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    100mg
    To inquire
  • Mcl-1 inhibitor 16


    Mcl-1 Inhibitor 16 (Compound 9), a platinum-based mitochondrial-targeting agent, inhibits Mcl-1 and induces Bax/Bak-dependent apoptosis in cancer cells.
    Formula:C25H29Cl2N3Pt
    Color and Shape:Solid
    Molecular weight:637.51

    Ref: TM-T79242

    5mg
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    50mg
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  • MYC-RIBOTAC


    MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered
    Formula:C55H58N10O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1067.17

    Ref: TM-T78055

    5mg
    To inquire
    50mg
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  • TAPI 0

    CAS:
    ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
    Formula:C24H32N4O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:456.54

    Ref: TM-TP2107

    1mg
    1,161.00€
  • (-)-Mcl-1 inhibitor 21

    CAS:

    (-)-Mcl-1 inhibitor 21 (Example 1-38) is an Mcl-1 inhibitor with an IC50 of 7.51 μM. It exhibits pro-apoptotic and anti-proliferative activity against SUDHL5 and SUDHL10 cell lines, making it useful for cancer research.

    Formula:C32H33N3O4
    Color and Shape:Solid
    Molecular weight:523.622

    Ref: TM-T204636

    10mg
    To inquire
    50mg
    To inquire
  • Thalidomide-O-C8-NH2

    CAS:
    Thalidomide-O-C8-NH2 is a synthetic cereblon ligand & PROTAC linker, serving as an E3 ligase ligand-linker.
    Formula:C21H27N3O5
    Color and Shape:Solid
    Molecular weight:401.463

    Ref: TM-T39376

    25mg
    1,369.00€
  • Cyanoacetamide

    CAS:
    Cyanoacetamide has inhibitory activity against the myeloid leukaemia cell differentiation protein Mcl-1
    Formula:C3H4N2O
    Purity:97.04%
    Color and Shape:Needles From Alcohol White To Light Cream Crystalline Powder
    Molecular weight:84.08

    Ref: TM-T20453

    5g
    48.00€
    10g
    63.00€
    25g
    89.00€
  • Zalypsis

    CAS:
    Zalypsis, a transcription factor inhibitor, is used potentially for the treatment of lymphoma, and cervical carcinoma.
    Formula:C37H38F3N3O8
    Color and Shape:Solid
    Molecular weight:709.71

    Ref: TM-T29202

    25mg
    2,448.00€
    50mg
    3,222.00€
    100mg
    4,410.00€
  • Tubulin/MMP-IN-3


    Tubulin/MMP-IN-3 (Compound 15j) is a dual inhibitor of tubulin polymerization and MMP, effectively inhibiting MMP-2 and MMP-9 with IC50 values of 21.13 μM and 19.24 μM, respectively. It disrupts the NF-κB signaling pathway, leading to mitochondrial dysfunction and mitochondrial-dependent apoptosis. Tubulin/MMP-IN-3 shows antiproliferative activity in various cancer cells by causing cell cycle arrest at the G2/M phase and demonstrates antitumor effects in mouse models.
    Formula:C38H41N2O12P
    Color and Shape:Solid
    Molecular weight:748.712

    Ref: TM-T204105

    10mg
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    50mg
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  • HG-7-85-01

    CAS:
    HG-7-85-01 is a novel ATP-competitive and type II tyrosine kinase inhibitor targeting both wild-type and watchman mutant BCR-ABL, PDGFRα, Kit, and Src kinases.
    Formula:C31H31F3N6O2S
    Purity:98.08%
    Color and Shape:Solid
    Molecular weight:608.68

    Ref: TM-T38653

    1mg
    71.00€
    2mg
    92.00€
    5mg
    157.00€
    10mg
    241.00€
    25mg
    485.00€
    50mg
    690.00€
    100mg
    888.00€
  • GPLGIAGQ

    CAS:
    GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.
    Formula:C31H53N9O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:711.81

    Ref: TM-TP1535

    100mg
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    500mg
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  • EGFR-IN-86


    EGFR-IN-86 (compound 4i), an EGFR inhibitor (IC50: 1.5 nM), demonstrates potent activity against glioblastoma by inducing apoptosis and causing G2/M phase cell
    Formula:C20H21N7O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:423.49

    Ref: TM-T78862

    5mg
    To inquire
    50mg
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  • Anticancer agent 102

    CAS:
    Anticancer Agent 102, a tetracaine derivative, exhibits anti-cancer activity by inducing apoptosis [1].
    Formula:C20H19F6N3O
    Color and Shape:Solid
    Molecular weight:431.37

    Ref: TM-T74767

    5mg
    To inquire
    50mg
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  • HDAC3-IN-6


    HDAC3-IN-6 (Compound SC26) is a selective HDAC3 inhibitor with an IC50 of 53 nM. It induces PD-L1 expression in a dose-dependent manner and leads to significant apoptosis and reactive oxygen species (ROS) production. HDAC3-IN-6 exhibits strong antitumor efficacy against colorectal cancer.
    Formula:C23H23N5O3
    Color and Shape:Solid
    Molecular weight:417.46

    Ref: TM-T205688

    10mg
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    50mg
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  • CAY10678

    CAS:
    CAY10678 is an mPGES-1 inhibitor that inhibits PD-1.CAY10678 reduces collagen deposition and T-cell depletion, and may be used to study melanoma.CASHIPS
    Formula:C23H34N4O
    Purity:99.66%
    Color and Shape:Solid
    Molecular weight:382.54

    Ref: TM-T38369

    1mg
    50.00€
    5mg
    114.00€
    10mg
    170.00€
    25mg
    334.00€
    50mg
    505.00€
    100mg
    713.00€
    500mg
    1,468.00€
  • Apoptolidin

    CAS:
    Apoptolidin, from Nocardiopsis, induces apoptosis, targets mitochondrial ATPase (Ki 4-5 μM), kills glial cells, and has antibiotic and antifungal properties.
    Formula:C58H96O21
    Color and Shape:Solid
    Molecular weight:1129.385

    Ref: TM-T35605

    100µg
    592.00€
  • Z-VDVA-(DL-Asp)-FMK

    CAS:
    Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.
    Formula:C32H46FN5O11
    Color and Shape:Solid
    Molecular weight:695.742

    Ref: TM-T39344

    5mg
    873.00€
  • Thalidomide-O-amido-C6-NH2

    CAS:
    Thalidomide-O-amido-C6-NH2 is a synthetic E3 ligase used for PROTAC creation, containing cereblon ligand and linker.
    Formula:C21H26N4O6
    Color and Shape:Solid
    Molecular weight:430.45

    Ref: TM-T39361

    100mg
    To inquire
    500mg
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  • BCMA72-80

    CAS:
    BCMA72-80: HLA-A2-specific peptide with high affinity; used in multiple myeloma and other BCMA+ tumor research.
    Formula:C59H97N13O11S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1196.55

    Ref: TM-TP1806

    100mg
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    500mg
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  • Enpp/Carbonic anhydrase-IN-1

    CAS:
    Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent inhibitor of Enpp and carbonic anhydrase.
    Formula:C23H25NO4S
    Purity:99.96%
    Color and Shape:Soild
    Molecular weight:411.51

    Ref: TM-T67775

    10mg
    46.00€
    25mg
    86.00€
    50mg
    129.00€
    100mg
    203.00€
    200mg
    288.00€
  • Spiroplatin

    CAS:
    Spiroplatin (TNO-6) is a novel platinum-containing analogue with antitumor activity that is commonly used in the study of solid tumors.
    Formula:C8H18N2O4PtS
    Purity:≥98%
    Color and Shape:Solid
    Molecular weight:433.39

    Ref: TM-T68144

    1mg
    175.00€
    5mg
    434.00€
    10mg
    622.00€
    25mg
    973.00€
    50mg
    1,341.00€
  • BC011


    BC011 is a human monoclonal antibody (mAb) targeting TNFRSF1B. It enhances the proliferation of CD8+ T cells and depletes Treg cells, resulting in an increased proportion of effector T cells within the tumor microenvironment. BC011 is applicable in the study of tumor immunology.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1592

    1mg
    To inquire
    5mg
    To inquire
  • Ganoderic acid Mk

    CAS:
    GA-Mk is a triterpenoid from Ganoderma lucidum mycelia, inhibits HeLa cell growth, and induces apoptosis via mitochondria; used in cervical cancer studies.
    Formula:C34H50O7
    Color and Shape:Solid
    Molecular weight:570.76

    Ref: TM-T75629

    5mg
    To inquire
    50mg
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  • YW-N-7 TFA


    YW-N-7 (TFA) is a PROTAC designed to target, inhibit, and degrade RET kinase, demonstrating a DC50 of 88 nM. It exhibits antitumor activity in xenograft mouse models driven by KIF5B-RET, making it a valuable compound for cancer research.
    Formula:C58H63F3N12O9
    Color and Shape:Solid
    Molecular weight:1129.19

    Ref: TM-T205127

    10mg
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    50mg
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  • GB-223


    GB-223 is a human monoclonal antibody (mAb) that targets TNFSF11/RANKL/CD254. It is applicable in the study of giant cell tumors of bone and postmenopausal osteoporosis.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1603

    1mg
    To inquire
    5mg
    To inquire
  • GSK2800528


    GSK2800528 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa, utilized for research related to inflammation and psoriasis.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-1727

    1mg
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    5mg
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  • Placulumab

    CAS:
    Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.
    Color and Shape:Liquid

    Ref: TM-T77114

    5mg
    To inquire
  • Ferumoxytol

    CAS:
    Ferumoxytol is an iron oxide nanoparticle with anti-leukemia properties, specifically against acute myeloid leukemia (AML) cells with low ferroportin (FPN) expression. By increasing intracellular iron levels, Ferumoxytol induces the Fenton reaction to produce reactive oxygen species (ROS), resulting in oxidative stress and ferroptosis. It selectively kills leukemia cells with low FPN expression while sparing normal cells, making it useful for studying leukemia targeting iron metabolism abnormalities.
    Color and Shape:Solid

    Ref: TM-T207484

    10mg
    To inquire
    50mg
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  • Baminercept

    CAS:
    Baminercept (BG 9924) is a lymphotoxin-β receptor-immunoglobulin fusion protein that blocks the lymphotoxin-letter/LIGHT axis.
    Purity:95% (SDS-PAGE); 98.3% (SEC-HPLC) - 95% (SDS-PAGE); 98.3% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:46.88 kDa

    Ref: TM-T78303

    1mg
    371.00€
    5mg
    964.00€
    10mg
    1,549.00€
  • Dazodalibep

    CAS:
    Dazodalibep (MEDI 4920; VIB 4920) is a monoclonal antibody that specifically targets CD40LG/TNFSF5 and is fused to human serum albumin (ALB/HSA) [1].
    Color and Shape:Liquid

    Ref: TM-T82606

    1mg
    To inquire
    5mg
    To inquire
  • PROTAC RIPK degrader-6

    CAS:
    PROTAC RIPK degrader-6 (example 1) is a PROTAC designed for the targeted degradation of RIP Kinase, featuring a RIP2 kinase inhibitor connected through a linker
    Formula:C43H48N6O11S2
    Color and Shape:Solid
    Molecular weight:889.01

    Ref: TM-T36243

    5mg
    808.00€
    10mg
    1,156.00€
    25mg
    1,890.00€
    1mL*10mM (DMSO)
    693.00€
  • Rosamultic acid


    Rosamultic acid is a useful organic compound for research related to life sciences and the catalog number is T125342.
    Formula:C30H46O5
    Color and Shape:Solid
    Molecular weight:486.693

    Ref: TM-T125342

    1mg
    To inquire
    5mg
    To inquire
  • Lodapolimab

    CAS:
    Lodapolimab (LY3300054) is an IgGλ anti- PD-1 monoclonal antibody [1] .
    Color and Shape:Liquid

    Ref: TM-T77068

    5mg
    To inquire
  • Hematein

    CAS:
    Hematein blocks Akt/PKB, Wnt signaling, promotes apoptosis in lung cancer, is a dye from hematoxylin, and inhibits casein kinase II (IC50: 0.74 μM).
    Formula:C16H12O6
    Purity:98%
    Color and Shape:Dark Brown Crystalline Powder
    Molecular weight:300.26

    Ref: TM-T15469

    100mg
    33.00€
    1mL*10mM (DMSO)
    52.00€