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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6170 products of "Apoptosis"

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  • EGFR/BRAFV600E-IN-3


    EGFR/BRAFV600E-IN-3 is an inhibitor targeting EGFR, BRAFV600E, and EGFRT790M with IC50 values of 57 nM, 68 nM, and 9.70 nM, respectively.
    Formula:C25H18N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:422.44

    Ref: TM-T78850

    5mg
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    50mg
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  • BRD4 Inhibitor-39


    BRD4 Inhibitor-39 (compound 12m) is an orally active inhibitor of BRD4 with an IC50 of 0.02 μM. It can induce apoptosis and demonstrates antitumor activity.
    Formula:C24H19BrFN9
    Color and Shape:Solid
    Molecular weight:532.37

    Ref: TM-T204232

    10mg
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    50mg
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  • Mcl-1 inhibitor 14


    Compound (Ra)-10, also known as Mcl-1 inhibitor 14, is a potent inhibitor of myeloid cell leukemia-1 (MCL-1), exhibiting a K_i of 0.018 nM, and holds potential
    Formula:C39H41ClFN5O5S
    Color and Shape:Solid
    Molecular weight:746.29

    Ref: TM-T79215

    5mg
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    50mg
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  • DiPT-4


    DiPT-4, a dual TOP1/PARP1 inhibitor, effectively induces DNA double-strand breaks (DSBs), cell cycle arrest, and apoptosis in cancer cells, with potential to
    Formula:C32H22FN5O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:591.61

    Ref: TM-T78747

    5mg
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    50mg
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  • Pimagedine

    CAS:
    Pimagedine is a prototype therapeutic agent for the prevention of formation of advanced glycation endproducts.
    Formula:CH6N4
    Color and Shape:Solid
    Molecular weight:74.09

    Ref: TM-T34066

    25mg
    1,369.00€
  • Distamycin A

    CAS:
    Distamycin A (NSC-82150), oligopeptide antibiotic, binds A/T rich DNA, affects cleavage sites, enhances apoptosis.
    Formula:C22H27N9O4
    Color and Shape:Solid
    Molecular weight:481.51

    Ref: TM-T73730

    5mg
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    50mg
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  • PH14


    PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for PI3Kα and 24.5 nM for HDAC3.
    Purity:98%
    Color and Shape:Odour Solid

    Ref: TM-T81499

    5mg
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    50mg
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  • Pralnacasan

    CAS:
    Pralnacasan blocks IL-18, IL-1β, IFN-γ. It’s a potent oral enzyme inhibitor with use in arthritis therapy (Ki: 1.4 nM).
    Formula:C26H29N5O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:523.54

    Ref: TM-T16570

    25mg
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    50mg
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    100mg
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  • U7D-1


    U7D-1: First-class USP7 PROTAC degrader, DC50 33 nM, anticancer, induces apoptosis in Jeko-1.
    Formula:C53H65N9O7
    Color and Shape:Solid
    Molecular weight:940.14

    Ref: TM-T74682

    5mg
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    50mg
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  • Ch282-5

    CAS:
    Ch282-5, an orally active inhibitor targeting the Bcl-2 protein, promotes mitochondria-dependent apoptosis (Apoptosis) by disrupting mitophagy and the mTOR pathway. It demonstrates antiproliferative effects on colorectal cancer cells, effective both in vitro and in vivo, while also inhibiting metastasis. Further, Ch282-5 augments Oxaliplatin-induced autophagy (Autophagy) by downregulating Mcl-1 protein and raising platelet count, which helps mitigate the adverse effects of Navitoclax.
    Formula:C34H34N2Na2O14S2
    Color and Shape:Solid
    Molecular weight:804.75

    Ref: TM-T200076

    10mg
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    50mg
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  • NCT-58

    CAS:
    NCT-58 is a potent HSP90 inhibitor that blocks Akt, downregulates HER family, and induces apoptosis in HER2+ breast cancer without triggering HSR.
    Formula:C27H34N2O5
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:466.57

    Ref: TM-T9996

    2mg
    43.00€
    5mg
    80.00€
    10mg
    119.00€
    25mg
    245.00€
    50mg
    394.00€
    100mg
    627.00€
    200mg
    842.00€
    1mL*10mM (DMSO)
    197.00€
  • PTD10

    CAS:
    PTD10 is a BTK-targeting PROTAC degradator, induces apoptosis via caspase-dependent and mitochondrial pathways, B-cell dysregulation.
    Formula:C49H51N11O8
    Purity:99.12%
    Color and Shape:Solid
    Molecular weight:922.99

    Ref: TM-T79201

    1mg
    224.00€
    5mg
    545.00€
    10mg
    855.00€
    25mg
    1,295.00€
    50mg
    1,690.00€
    100mg
    2,275.00€
  • Rozanolixizumab

    CAS:

    Rozanolixizumab (RYSTIGGO) is a humanized IgG4 monoclonal antibody that targets FcRn in newborns for autoimmune research.

    Purity:SDS-PAGE:97.2%;SEC-HPLC:95.9%
    Color and Shape:Liquid
    Molecular weight:145.19 kDa

    Ref: TM-T39057

    1mg
    216.00€
    5mg
    472.00€
    10mg
    755.00€
    25mg
    1,121.00€
    50mg
    1,501.00€
  • Antitumor agent-116


    Antitumor Agent-116 (Compound 6C) is an anti-tumor agent that exhibits anti-proliferative properties and induces apoptosis.
    Formula:C31H23BrN4O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:627.51

    Ref: TM-T79582

    5mg
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    50mg
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  • Verdinexor

    CAS:
    Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.
    Formula:C18H12F6N6O
    Purity:98% - 99.68%
    Color and Shape:Solid
    Molecular weight:442.32

    Ref: TM-T6123

    1mg
    35.00€
    5mg
    111.00€
    10mg
    187.00€
    25mg
    341.00€
    50mg
    567.00€
    100mg
    905.00€
    200mg
    1,216.00€
    1mL*10mM (DMSO)
    123.00€
  • HTR2A antagonist 1


    HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.
    Formula:C35H43Cl2F2N5O4
    Color and Shape:Solid
    Molecular weight:706.65

    Ref: TM-T204966

    10mg
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    50mg
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  • ROS inducer 4


    Compound TE3, also known as ROS inducer 4, serves as a mitochondrial inhibitor. This compound induces a variety of mitochondria-related physiological alterations in tumors, including mitochondrial fragmentation, intense generation and accumulation of ROS, reduced mitochondrial membrane potential, and lower ATP content. Additionally, it activates ROS-mediated apoptotic signaling within mitochondria.
    Formula:C49H62BrO4P
    Color and Shape:Solid
    Molecular weight:825.89

    Ref: TM-T89939

    10mg
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    50mg
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  • Topoisomerase I/II inhibitor 6


    TopoisomeraseI/II inhibitor 6 (compound 3i) acts as an effective inhibitor of topoisomerase I and II, with IC50 values of 4.77 µM and 15 µM, respectively. Additionally, it exhibits antiproliferative activity against the human melanoma cell line LOX IMVI, demonstrating IC50 values of 26.7 µM and 25.4 µM.
    Formula:C31H28F2N4O6S
    Color and Shape:Solid
    Molecular weight:622.64

    Ref: TM-T201278

    10mg
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    50mg
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  • PRMT5-IN-31


    PRMT5-IN-31 (Compound 3m), a selective PRMT5 inhibitor (IC50: 0.31 μM), increases hnRNP E1 protein levels by occupying the substrate site of PRMT5 and
    Formula:C21H24N2O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.43

    Ref: TM-T79274

    5mg
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    50mg
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  • Streptonigrin

    CAS:
    Streptonigrin, from Streptomyces flocculus, has anti-tumor and anti-bacterial properties, inhibiting PAD1-4.
    Formula:C25H22N4O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:506.46

    Ref: TM-T16946

    1mg
    548.00€
    5mg
    2,403.00€
  • (E/Z)-10-Hydroxy-2-decenoic acid

    CAS:
    (E/Z)-10-Hydroxy-2-decenoic acid is a useful organic compound for research related to life sciences.
    Formula:C10H18O3
    Color and Shape:Solid
    Molecular weight:186.251

    Ref: TM-T124254

    1mg
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    5mg
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  • S65487 hydrochloride

    CAS:
    S65487 (VOB560) hydrochloride, a potent and selective Bcl-2 inhibitor, is effective against BCL-2 mutations, including G101V and D103Y.
    Formula:C41H42Cl2N6O4
    Color and Shape:Solid
    Molecular weight:753.73

    Ref: TM-T39135

    10mg
    627.00€
    25mg
    1,341.00€
  • Enterodiol


    Enterodiol is a natural product that can be used as a reference standard.
    Formula:C18H22O4
    Color and Shape:Solid
    Molecular weight:302.37

    Ref: TM-T124226

    1mg
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    5mg
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  • Toremifene citrate

    CAS:
    Toremifene citrate is a selective estrogen receptor modulator (SERM). It is an estrogen agonist for bone tissue and cholesterol metabolism but is antagonistic on the mammary and uterine tissue.
    Formula:C32H36ClNO8
    Purity:99.83% - >99.99%
    Color and Shape:White Or Almost White Powder
    Molecular weight:598.08

    Ref: TM-T1464

    1g
    120.00€
    2g
    173.00€
    50mg
    34.00€
    100mg
    46.00€
    500mg
    93.00€
    1mL*10mM (DMSO)
    49.00€
  • Thalidomide-NH-C6-NH2 TFA

    CAS:
    Thalidomide-based cereblon ligand linked to PROTAC technology as E3 ligase ligand-linker.
    Formula:C21H25F3N4O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:486.44

    Ref: TM-T18809

    2mg
    63.00€
    5mg
    92.00€
  • HDAC-IN-77


    HDAC-IN-77 (HL-5s), an HDAC inhibitor, has the capability to induce ferroptosis and suppress the Nrf2/HO-1 signaling pathway. This compound is utilized in cancer research.
    Formula:C22H26N4O2S
    Color and Shape:Solid
    Molecular weight:410.53

    Ref: TM-T200029

    10mg
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    50mg
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  • Verproside

    CAS:
    Verproside is a useful organic compound for research related to life sciences. The catalog number is T124745 and the CAS number is 50932-20-2.
    Formula:C22H26O13
    Color and Shape:Solid
    Molecular weight:498.437

    Ref: TM-T124745

    1mg
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    5mg
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  • AS-99 TFA


    AS-99 TFA: potent ASH1L inhibitor, IC50=0.79 μM, combats leukemia, inhibits cell growth, induces apoptosis.
    Color and Shape:Solid

    Ref: TM-T36978

    5mg
    482.00€
    10mg
    818.00€
  • PROTAC KDM4 degrader-1


    PROTACKDM4 degrader-1 (Compound 11) is a proteolysis-targeting chimera (PROTAC) degrader specifically designed for KDM4. It effectively degrades KDM4A-C while sparing KDM4D. In esophageal cancer cells, PROTACKDM4 degrader-1 demonstrates strong antiproliferative activity, inducing apoptosis and cell cycle arrest, and inhibits lysine demethylation of histone H3.
    Color and Shape:Odour Solid

    Ref: TM-T206971

    10mg
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    50mg
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  • NQO2-IN-1

    CAS:
    NQO2-IN-1, a resveratrol analog, is a potent NQO2 inhibito,antitumor,generation of ROS and up-regulation of DR5 (death receptor 5) to promote apoptosis.
    Formula:C18H18N2O3
    Purity:99.83%
    Color and Shape:Soild
    Molecular weight:310.35

    Ref: TM-T203013

    1mg
    128.00€
    5mg
    305.00€
    10mg
    444.00€
    25mg
    686.00€
    50mg
    947.00€
    100mg
    1,180.00€
    200mg
    1,602.00€
  • Aphidicolin

    CAS:
    Aphidicolin blocks DNA synthesis, hinders herpes virus growth, and stimulates apoptosis in leukemia cells; it's a mold-derived DNA polymerase inhibitor.
    Formula:C20H34O4
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:338.48

    Ref: TM-T14304

    1mg
    274.00€
  • Thalidomide-O-amido-PEG4-azide

    CAS:
    Thalidomide-O-amido-PEG4-azide is a polyethylene glycol (PEG) derivative serving as a linker for Proteolysis Targeting Chimeras (PROTACs) synthesis [1].
    Formula:C25H32N6O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:576.56

    Ref: TM-T18821

    2mg
    62.00€
    5mg
    90.00€
    10mg
    130.00€
    25mg
    212.00€
    50mg
    339.00€
    100mg
    532.00€
  • CS4


    CS4 is a selective HDAC inhibitor, with IC50 values for HDAC1, HDAC6, HDAC8, HDAC4, and HDAC11 reported as 38 nM, 12 nM, 5.8 μM, 19 μM, and 61 μM, respectively. It enhances the acetylation of α-tubulin and histone 3 (histone 3). Additionally, CS4 activates PPARγ and blocks glycolysis (glycolysis). It induces cell cycle arrest at the G2 phase and triggers apoptosis (apoptosis), exhibiting anticancer effects both in vitro and in vivo.
    Color and Shape:Odour Solid

    Ref: TM-T206840

    10mg
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    50mg
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  • CRA-026440 hydrochloride

    CAS:
    CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor.
    Formula:C23H25ClN4O4
    Purity:99.78%
    Color and Shape:Soild
    Molecular weight:456.92

    Ref: TM-T10883L

    1mg
    115.00€
    5mg
    274.00€
    10mg
    432.00€
    25mg
    735.00€
    50mg
    1,159.00€
    100mg
    1,568.00€
    1mL*10mM (DMSO)
    47.00€
  • Lesigercept


    Lesigercept is a humanized antibody that targets IGHE.
    Color and Shape:Odour Liquid

    Ref: TM-T9901A-374

    1mg
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    5mg
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  • YN14-H


    YN14-H is a PROTAC degrader that targets KRASG12C. It effectively inhibits the growth of NCI-H358 and MIA PaCa-2 cells, with IC50 values of 0.042 μM and 0.021 μM, respectively, and DC50 values of 28.9 nM and 18.1 nM. YN14-H significantly induces apoptosis and suppresses cell migration. It demonstrates favorable pharmacokinetics and excellent in vivo antitumor activity.
    Color and Shape:Odour Solid

    Ref: TM-T206431

    10mg
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    50mg
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  • PD1-PDL1-IN 1 TFA


    PD1-PDL1-IN 1 TFA (compound 16) is a potent inhibitor of programmed cell death 1 (PD-1), functioning as an immune modulator [1].
    Formula:C16H24F3N7O8
    Color and Shape:Solid
    Molecular weight:499.4

    Ref: TM-T73630

    5mg
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    50mg
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  • Dehydroaltenusin

    CAS:
    Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM).
    Formula:C15H12O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:288.255

    Ref: TM-T15094

    25mg
    1,369.00€
  • Albanol B

    CAS:
    Albanol B, from mulberries, combats Alzheimer's, bacteria, and oxidation, hinders cancer growth, and triggers cell arrest and apoptosis.
    Formula:C34H22O8
    Color and Shape:Solid
    Molecular weight:558.53

    Ref: TM-T75602

    5mg
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    50mg
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  • A947

    CAS:
    A947 is a potent and selective SMARCA2 PROTAC that induces the degradation of SMARCA2, with significant antitumor activity in SMARCA4-mutant NSCLC cells.
    Formula:C61H76N12O7S
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:1121.4

    Ref: TM-T74686

    1mg
    1,083.00€
    5mg
    2,311.00€
    10mg
    3,465.00€
  • VEGFR/PARP-IN-1


    VEGFR/PARP-IN-1 (Compound 14b) is a dual inhibitor of VEGFR and PARP with IC50 values of 191 nM and 60.9 nM, respectively.
    Formula:C29H27N9O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:517.58

    Ref: TM-T79647

    5mg
    To inquire
    50mg
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  • 3MB-PP1

    CAS:
    3MB-PP1 is a bulky purine analog and a Polo-like kinase 1 (Plk1) inhibitor.
    Formula:C17H21N5
    Purity:99.96%
    Color and Shape:White Solid
    Molecular weight:295.38

    Ref: TM-T21678

    5mg
    50.00€
    10mg
    92.00€
    25mg
    166.00€
    50mg
    255.00€
    100mg
    374.00€
    500mg
    To inquire
    1mL*10mM (DMSO)
    55.00€
  • dTAG-47

    CAS:
    dTAG-47 targets FKBP12 F36V for protein degradation, useful in basal-like breast cancer research.
    Formula:C59H73N5O14
    Color and Shape:Solid
    Molecular weight:1076.24

    Ref: TM-T74556

    5mg
    1,584.00€
  • ICy-OH

    CAS:
    ICy-OH, an iodinated anticancer photosensitizer, excels in deep tissue imaging (640 nm excitation) and triggers pyroptosis in pancreatic cancer cells.
    Formula:C26H25I2NO2
    Color and Shape:Solid
    Molecular weight:637.29

    Ref: TM-T74922

    5mg
    To inquire
    50mg
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  • Avotaciclib hydrochloride


    Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic use in specific malignancies, including
    Formula:C13H12ClN7O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:317.73

    Ref: TM-T78137

    5mg
    To inquire
    50mg
    To inquire
  • PZ703b TFA


    PZ703b TFA, a Bcl-xl PROTAC degradation agent, promotes apoptosis and halts bladder cancer cell proliferation, making it a pertinent investigative compound for
    Formula:C82H103ClF6N10O13S4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1714.46

    Ref: TM-T77913

    5mg
    To inquire
    50mg
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  • BMf-BH3


    BMf-BH3 is a Bcl-2 family peptide, key in HDAC inhibition affecting acetylation balance.
    Formula:C131H214N45O35S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:3012.5

    Ref: TM-TP1836

    100mg
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    500mg
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  • dPDL1-4


    dPDL1-4 is a potent and selective eHSPTAC eHSP90PD-L1 degrader, with DC50 values of 7.77 μM (HeLa) and 6.52 μM (B16F10). It links eHSP90 to target proteins, inducing lysosomal degradation. dPDL1-4 effectively degrades PD-L1 and inhibits tumor growth, making it useful for research in cervical cancer and melanoma.
    Color and Shape:Odour Solid

    Ref: TM-T211758

    10mg
    To inquire
    50mg
    To inquire
  • Thalidomide-O-PEG4-azide

    CAS:
    Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
    Formula:C23H29N5O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:519.5

    Ref: TM-T18828

    2mg
    82.00€
  • SC-2001

    CAS:
    SC-2001 inhibits MCL-1 and STAT3, enhances SHP-1, induces apoptosis in breast cancer, and counters STAT3-driven sorafenib resistance in liver cancer.
    Formula:C18H14BrN3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:368.23

    Ref: TM-T28697

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€