Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5593 products of "Apoptosis"
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CHS-828
CAS:<p>CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).</p>Formula:C19H22ClN5OPurity:98% - 99.9%Color and Shape:SolidMolecular weight:371.86MSC 2032964A
CAS:<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Formula:C16H13F3N6OPurity:99.76%Color and Shape:SolidMolecular weight:362.31AZD1208 hydrochloride
CAS:<p>AZD1208 hydrochloride is a highly selective, potent and orally active PIM inhibitor.</p>Formula:C21H22ClN3O2SColor and Shape:SolidMolecular weight:415.94MG 149
CAS:<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Formula:C22H28O3Purity:98.69% - 99.86%Color and Shape:SolidMolecular weight:340.46Thalidomide-4-OH
CAS:<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Formula:C13H10N2O5Purity:99.59%Color and Shape:SolidMolecular weight:274.23SCR7 pyrazine
CAS:<p>SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).</p>Formula:C18H12N4OSPurity:98.72% - 99.85%Color and Shape:SolidMolecular weight:332.38VER-50589
CAS:<p>VER-50589 is a potent HSP90 inhibitor.</p>Formula:C19H17ClN2O5Purity:99.96% - >99.99%Color and Shape:SolidMolecular weight:388.8Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Formula:C18H18N2O3Purity:98.92% - 99.52%Color and Shape:SolidMolecular weight:310.35Sclareol
CAS:<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Formula:C20H36O2Purity:99.58% - 99.97%Color and Shape:White Fine PowderMolecular weight:308.5PUMA BH3 Free base
<p>PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of</p>Formula:C130H206N42O45SPurity:96.64%Color and Shape:SolidMolecular weight:3109.35Sirtinol
CAS:<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formula:C26H22N2O2Purity:97.12% - 99.96%Color and Shape:SolidMolecular weight:394.47TVB-3166
CAS:<p>TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).</p>Formula:C24H24N4OPurity:99.53% - 99.57%Color and Shape:SolidMolecular weight:384.47PD0166285
CAS:<p>PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.</p>Formula:C26H27Cl2N5O2Purity:99.23%Color and Shape:SolidMolecular weight:512.43TAK-243
CAS:<p>TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).</p>Formula:C19H20F3N5O5S2Purity:98.09% - 98.93%Color and Shape:SolidMolecular weight:519.52GS-444217
CAS:<p>GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).</p>Formula:C23H21N7OPurity:99.08%Color and Shape:SolidMolecular weight:411.46Glafenine Hydrochloride
CAS:<p>Glafenine Hydrochloride is an anti-inflammatory agent.</p>Formula:C19H17ClN2O4·HClPurity:98.89%Color and Shape:SolidMolecular weight:409.26Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Formula:C25H22N4O4Purity:99.27%Color and Shape:Orange To Red SolidMolecular weight:442.47Linderalactone
CAS:<p>1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.</p>Formula:C15H16O3Purity:99.79%Color and Shape:SolidMolecular weight:244.29Cynaroside
CAS:<p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>Formula:C21H20O11Purity:98% - >99.99%Color and Shape:SolidMolecular weight:448.38NVP-ADW742
CAS:<p>NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl</p>Formula:C28H31N5OPurity:96.14% - 98.70%Color and Shape:SolidMolecular weight:453.58Bigelovin
CAS:<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Formula:C17H20O5Purity:99.61% - 99.72%Color and Shape:SolidMolecular weight:304.34TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formula:C21H17ClN2O6Purity:97.62% - 99.09%Color and Shape:SolidMolecular weight:428.82Ketorolac hemicalcium
CAS:<p>Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.</p>Formula:C30H24CaN2O6Color and Shape:SolidMolecular weight:548.608Thalidomide-propargyl
CAS:<p>Thalidomide-propargyl, a Cereblon ligand, links proteins in PROTAC formation.</p>Formula:C16H12N2O5Purity:95.14%Color and Shape:SolidMolecular weight:312.28PI-1840
CAS:<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formula:C22H26N4O3Purity:98.82%Color and Shape:SolidMolecular weight:394.47Britannin
CAS:<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formula:C19H26O7Purity:98% - 99.98%Color and Shape:SolidMolecular weight:366.41Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Formula:C15H26OPurity:96.01%Color and Shape:Clear To Yellowish LiquidMolecular weight:222.37LY-294002 hydrochloride
CAS:<p>LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.</p>Formula:C19H17NO3·HClPurity:99.95%Color and Shape:SolidMolecular weight:343.81Zinc Protoporphyrin
CAS:<p>Zinc Protoporphyrin is an oral HO-1 inhibitor that reduces PG's protection against H2O2 and has anti-cancer properties.</p>Formula:C34H32N4O4ZnPurity:95.43% - 99.27%Color and Shape:SolidMolecular weight:626.02ELR510444
CAS:<p>ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.</p>Formula:C19H16N2O2S2Purity:97.67% - 98.69%Color and Shape:SolidMolecular weight:368.47Pemetrexed disodium hemipenta hydrate
CAS:<p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>Formula:C20H21N5O6·2NaH2OPurity:98.76%Color and Shape:SolidMolecular weight:518.43K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Formula:C13H15N3O2SPurity:>99.99%Color and Shape:SolidMolecular weight:277.34Isoalantolactone
CAS:<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>Formula:C15H20O2Purity:99.75% - 99.94%Color and Shape:SolidMolecular weight:232.32Alda-1
CAS:<p>Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.</p>Formula:C15H11Cl2NO3Purity:98.5% - 99.63%Color and Shape:SolidMolecular weight:324.16Thalidomide-PEG4-Propargyl
CAS:<p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>Formula:C24H28N2O9Purity:97.46%Color and Shape:SolidMolecular weight:488.49DC661
CAS:<p>DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.</p>Formula:C31H39Cl2N5Purity:99.07%Color and Shape:SolidMolecular weight:552.58Flavokawain A
CAS:<p>NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.</p>Formula:C18H18O5Purity:97.1% - 99.72%Color and Shape:SolidMolecular weight:314.332BIX01294 (hydrochloride hydrate)
CAS:<p>BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.</p>Formula:C28H43Cl3N6O3Color and Shape:SolidMolecular weight:618.04Temsirolimus
CAS:<p>Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.</p>Formula:C56H87NO16Purity:97.76% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:1030.29Zoledronic acid monohydrate
CAS:<p>Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.</p>Formula:C5H12N2O8P2Purity:99.91%Color and Shape:White To Off-White PowderMolecular weight:290.1Desoxyrhaponticin
CAS:<p>Deoxyrhaponticin may reduce post-meal blood sugar and inhibit cancer cell growth.</p>Formula:C21H24O8Purity:99.97% - ≥95%Color and Shape:SolidMolecular weight:404.41Amuvatinib
CAS:<p>Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.</p>Formula:C23H21N5O3SPurity:99.38% - >99.99%Color and Shape:SolidMolecular weight:447.51Bardoxolone
CAS:<p>Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.</p>Formula:C31H41NO4Purity:97.9% - 98.97%Color and Shape:SolidMolecular weight:491.66Tandutinib hydrochloride
CAS:<p>Tandutinib hydrochloride: FLT3 inhibitor (IC50 0.22 μM), targets c-Kit, PDGFR, treats AML, crosses blood-brain barrier.</p>Formula:C31H43ClN6O4Color and Shape:SolidMolecular weight:599.16Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Formula:C21H22O5Purity:99.03% - 99.9%Color and Shape:SolidMolecular weight:354.4BO-264
CAS:<p>BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).</p>Formula:C18H19N5O3Purity:98.03% - 99.81%Color and Shape:SolidMolecular weight:353.38Trifloxystrobin
CAS:<p>Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.</p>Formula:C20H19F3N2O4Purity:99.49%Color and Shape:SolidMolecular weight:408.37Toddaculin
CAS:<p>Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the</p>Formula:C16H18O4Purity:99.91%Color and Shape:SolidMolecular weight:274.31GSK1324726A
CAS:<p>GSK1324726A (I-BET726) is a greatly specific inhibitor of BET family proteins for BRD2(IC50=41 nM), BRD3(IC50=31 nM), and BRD4 (IC50=22 nM).</p>Formula:C25H23ClN2O3Purity:98.34% - 99.85%Color and Shape:SolidMolecular weight:434.91Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Formula:C24H29FN6·2CH4O3SPurity:98% - 99.38%Color and Shape:SolidMolecular weight:612.74
