Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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Autophagy-IN-A9
CAS:<p>Autophagy-IN-A9 is a bioactive chemical.</p>Formula:C15H11ClFN3Purity:99.72%Color and Shape:SolidMolecular weight:287.72Oxaprozin potassium
CAS:<p>Oxaprozin potassium is an oral COX inhibitor (IC50: 2.2 μM for COX-1, 36 μM for COX-2), induces apoptosis, and blocks NF-κB activation.</p>Formula:C18H14KNO3Color and Shape:SolidMolecular weight:331.412Amifostine trihydrate
CAS:<p>Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.</p>Formula:C5H15N2O3PS·3H2OPurity:99.71% - 99.80%Color and Shape:SolidMolecular weight:268.27Chlorfenapyr
CAS:<p>Chlorfenapyr (AC 303630) is a pyrrole insecticide and converts active substances (insecticidal activity) in insects by a multifunctional oxidase</p>Formula:C15H11BrClF3N2OPurity:99.33% - 99.49%Color and Shape:Off-White To Light Brown Powder With An Halide OdorMolecular weight:407.61Alemtuzumab
CAS:<p>Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.</p>Purity:97.2% (SDS-PAGE); 96.7% (SEC-HPLC) - 98.00%Color and Shape:LiquidMolecular weight:146.04 kDaBMS-1
CAS:<p>BMS-1 is a PD-1/PD-L1 inhibitor and immunomodulator; it targets the CD274 gene product, PD-L1, linked to tumor evasion and higher mortality.</p>Formula:C29H33NO5Purity:99.40% - 99.81%Color and Shape:SolidMolecular weight:475.58Citric acid monohydrate
CAS:<p>Citric Acid Monohydrate: tricarboxylic, from citrus, antioxidant, stabilizes drugs, preservative.</p>Formula:C6H10O8Purity:99.87%Color and Shape:White Solid CrystallineMolecular weight:210.14Protosappanin B
CAS:<p>Protosappanin B enhances cell survival, growth protein 43; degrades p53 via MDM2 ubiquitination.</p>Formula:C16H16O6Purity:98% - 98.86%Color and Shape:SolidMolecular weight:304.29Madecassoside
CAS:<p>Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activities</p>Formula:C48H78O20Purity:99.46% - 99.85%Color and Shape:White PowderMolecular weight:975.12Picropodophyllin
CAS:<p>Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.</p>Formula:C22H22O8Purity:98.88% - 99.62%Color and Shape:SolidMolecular weight:414.41HYPOCRELLIN B
CAS:<p>HYPOCRELLIN B, from Hypocrella bambusae, breaks DNA, triggers apoptosis in ovarian cells, and stops Staphylococcus growth via ROS.</p>Formula:C30H24O9Purity:98% - 98.87%Color and Shape:SolidMolecular weight:528.51Malachite green oxalate
CAS:<p>Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.</p>Formula:C23H25N2·C2HO4C2H2O4Color and Shape:Dark Green Crystals With A Metallic LusterMolecular weight:463.51Fosbretabulin Disodium
CAS:<p>Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).</p>Formula:C18H19O8P·2NaPurity:97.43% - 99.96%Color and Shape:White SolidMolecular weight:440.29Cabozantinib hydrochloride
CAS:<p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>Formula:C28H25ClFN3O5Purity:99.97%Color and Shape:SolidMolecular weight:537.96Liensinine
CAS:<p>1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.</p>Formula:C37H42N2O6Purity:98.92% - 99.93%Color and Shape:White-Like PowderMolecular weight:610.74Antineoplaston A10
CAS:<p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>Formula:C13H14N2O3Purity:99.42%Color and Shape:SolidMolecular weight:246.26Galanthamine
CAS:<p>Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.</p>Formula:C17H21NO3Purity:98.03% - 99.87%Color and Shape:Off-White SolidMolecular weight:287.35Cidofovir
CAS:<p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>Formula:C8H14N3O6PPurity:99.24% - 99.76%Color and Shape:Fluffy White PowderMolecular weight:279.19STM2457
CAS:<p>View and buy STM2457 from TargetMol.STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3.Cited in 2 publications.</p>Formula:C25H28N6O2Purity:97.44% - 98.90%Color and Shape:SolidMolecular weight:444.53BAI1
CAS:<p>BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).</p>Formula:C19H21Br2N3OPurity:97.74%Color and Shape:SolidMolecular weight:467.2Pictilisib
CAS:<p>Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).</p>Formula:C23H27N7O3S2Purity:98.69% - 99.97%Color and Shape:SolidMolecular weight:513.64ON1231320
CAS:<p>ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.</p>Formula:C22H15F2N5O3SPurity:97.31%Color and Shape:SolidMolecular weight:467.45ICCB-19 hydrochloride
CAS:<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Formula:C12H22ClN3OSPurity:99.3%Color and Shape:SolidMolecular weight:291.84PROCYANIDIN C1
CAS:<p>Procyanidin C1 is a natural polyphenol. It reduces Bcl-2 protein levels.Cost-effective and quality-assured.</p>Formula:C45H38O18Purity:97.01% - 99.86%Color and Shape:SolidMolecular weight:866.773,4-Dicaffeoylquinic acid
CAS:<p>3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.</p>Formula:C25H24O12Purity:96.33% - 98.82%Color and Shape:SolidMolecular weight:516.45Sophoraflavanone G
CAS:<p>Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related</p>Formula:C25H28O6Purity:97.09% - 99.77%Color and Shape:SolidMolecular weight:424.49CM-272
CAS:<p>CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.</p>Formula:C28H38N4O3Purity:97.83%Color and Shape:SolidMolecular weight:478.63Prexasertib dihydrochloride
CAS:<p>Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.</p>Formula:C18H21Cl2N7O2Purity:98.46% - 99.82%Color and Shape:SolidMolecular weight:438.31LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34Thalidomide-O-C4-NH2 hydrochloride
CAS:<p>Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.</p>Formula:C17H20ClN3O5Purity:98.33%Color and Shape:SolidMolecular weight:381.81PF-3758309 dihydrochloride
<p>PF-3758309 dihydrochloride is a potent PAK4 inhibitor (Kd = 2.7 nM, Ki = 18.7 nM), oral, ATP-competitive; blocks cell growth, induces apoptosis.</p>Formula:C25H32Cl2N8OSColor and Shape:SolidMolecular weight:563.55MG-101
CAS:<p>MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins.</p>Formula:C20H37N3O4Purity:98% - ≥98%Color and Shape:SolidMolecular weight:383.53Tomatine
CAS:<p>Tomatine (lycopersicin) is an antiproliferatve agent of breast adenocarcinoma cells.</p>Formula:C50H83NO21Purity:98.42% - 99.94%Color and Shape:White To Light YellowMolecular weight:1034.19PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formula:C16H17N3O4SPurity:98.74% - 99.19%Color and Shape:SolidMolecular weight:347.39CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Formula:C26H31BrN8OPurity:98.51% - 99.89%Color and Shape:SolidMolecular weight:551.48ASP3026
CAS:<p>ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.</p>Formula:C29H40N8O3SPurity:98.78% - 99.81%Color and Shape:SolidMolecular weight:580.74α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formula:C10H16OPurity:97.02% - 98.41%Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Molecular weight:152.23Voreloxin hydrochloride
CAS:<p>Voreloxin hydrochloride (SNS-595 hydrochloride) is a potent inhibitor of Topoisomerase II with broad-spectrum anti-tumor activity.</p>Formula:C18H20ClN5O4SPurity:99.84%Color and Shape:SolidMolecular weight:437.9Fasentin
CAS:<p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>Formula:C11H9ClF3NO2Purity:99.95%Color and Shape:SolidMolecular weight:279.64Diallyl Trisulfide
CAS:<p>Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.</p>Formula:C6H10S3Purity:95% - ≥98%Color and Shape:LiquidMolecular weight:178.34Capmatinib 2HCl
CAS:<p>Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.</p>Formula:C23H19Cl2FN6OPurity:98.80%Color and Shape:SolidMolecular weight:485.34Indinavir sulfate
CAS:<p>Indinavir sulfate (L735524 sulfate) is a HIV protease inhibitor.It inhibits the HIV-1 protease with an IC50 value of 0.41 nM and Ki value of 0.24 nM.</p>Formula:C36H49N5O8SPurity:99.75% - >99.99%Color and Shape:White PowderMolecular weight:711.87Mitoxantrone diacetate
CAS:<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Formula:C26H36N4O10Color and Shape:SolidMolecular weight:564.592SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Formula:C14H8N2OPurity:97.63% - 99.82%Color and Shape:SolidMolecular weight:220.23ONO-8130
CAS:<p>ONO-8130 is an orally available antagonist of EP1 receptor.</p>Formula:C25H28N2O5S2Purity:97.82%Color and Shape:SolidMolecular weight:500.63Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formula:C32H46O8Purity:97.1% - 99.33%Color and Shape:SolidMolecular weight:558.7HS-1793
CAS:<p>HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.</p>Formula:C16H12O3Purity:98.16% - 99.82%Color and Shape:SolidMolecular weight:252.26MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formula:C20H19ClFN5OSPurity:99.09% - 99.79%Color and Shape:SolidMolecular weight:431.91PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Formula:C17H17N7Purity:98.45% - 99.67%Color and Shape:SolidMolecular weight:319.36Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Formula:C9H10O4Purity:99.88%Color and Shape:White Crystal Or PowderMolecular weight:182.17
