Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formula:C21H21N3O2SPurity:97.24% - 99.83%Color and Shape:SolidMolecular weight:379.48Niraparib hydrochloride
CAS:<p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>Formula:C19H21ClN4OPurity:99.26%Color and Shape:SolidMolecular weight:356.85Polydatin
CAS:<p>Polydatin, a resveratrol glycoside from Polygonum cuspidatum, inhibits platelet aggregation, alters lipid ratios, and modulates cell functions.</p>Formula:C20H22O8Purity:97.2% - 98.94%Color and Shape:White Fine PowderMolecular weight:390.38Galgravin
CAS:<p>Galgravin combats inflammation, safeguards neurons, promotes neurite growth, and resists Abeta25-35 and MPP+ toxicity.</p>Formula:C22H28O5Purity:99.75% - 99.88%Color and Shape:SolidMolecular weight:372.45SNS-032
CAS:<p>SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.</p>Formula:C17H24N4O2S2Purity:98.27% - 99.91%Color and Shape:SolidMolecular weight:380.53NPS-1034
CAS:<p>NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.</p>Formula:C31H23F2N5O3Purity:98.48%Color and Shape:SolidMolecular weight:551.54EB-3D
CAS:<p>EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.</p>Formula:C30H36Br2N4O2Purity:99.48%Color and Shape:SolidMolecular weight:644.4NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Formula:C27H34N4O5Purity:99.59%Color and Shape:SolidMolecular weight:494.58Linifanib
CAS:<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formula:C21H18FN5OPurity:98% - 98.24%Color and Shape:SolidMolecular weight:375.4GW 5074
CAS:<p>GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.</p>Formula:C15H8Br2INO2Purity:99.32%Color and Shape:SolidMolecular weight:520.94YH239-EE
CAS:<p>YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.</p>Formula:C25H27Cl2N3O4Purity:99.61%Color and Shape:SolidMolecular weight:504.413,6-Dihydroxyflavone
CAS:<p>3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.</p>Formula:C15H10O4Purity:99.92%Color and Shape:SolidMolecular weight:254.24Alofanib
CAS:<p>Alofanib (RPT835) selectively inhibits FGFR2 in KATO III cells with IC50 <10 nM; doesn’t affect FGFR1/3 or FGF2-FGFR2 binding.</p>Formula:C19H15N3O6SPurity:99.53% - 99.81%Color and Shape:SolidMolecular weight:413.4Oroxin B
CAS:<p>Oroxin B (Hypocretin-2) has antioxidant activity.</p>Formula:C27H30O15Purity:98.22% - 99.81%Color and Shape:SolidMolecular weight:594.52Thonningianin A
CAS:<p>Thonningianin A: an anti-cancer compound with antioxidant effects, GST inhibitor, and radical scavenger.</p>Formula:C42H34O21Purity:98.37% - 99.94%Color and Shape:SolidMolecular weight:874.71CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Formula:C34H43N3O3Purity:98.3% - 99.61%Color and Shape:SolidMolecular weight:541.72Pralatrexate
CAS:<p>Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate</p>Formula:C23H23N7O5Purity:94.32% - 99.59%Color and Shape:SolidMolecular weight:477.47Vistusertib
CAS:<p>Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.</p>Formula:C25H30N6O3Purity:97.08% - 99.06%Color and Shape:SolidMolecular weight:462.54ML385
CAS:<p>ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.</p>Formula:C29H25N3O4SPurity:98.08% - >99.99%Color and Shape:SolidMolecular weight:511.59Vandetanib
CAS:<p>Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.</p>Formula:C22H24BrFN4O2Purity:99.7% - >99.99%Color and Shape:White SolidMolecular weight:475.35tubuloside B
CAS:<p>Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.</p>Formula:C31H38O16Purity:97.59% - 99.72%Color and Shape:SolidMolecular weight:666.62JX06
CAS:<p>JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.</p>Formula:C10H16N2O2S4Purity:99.4%Color and Shape:SolidMolecular weight:324.51MK-2206 dihydrochloride
CAS:<p>MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and</p>Formula:C25H23Cl2N5OPurity:99.228% - 99.94%Color and Shape:SolidMolecular weight:480.39Geranyl acetate
CAS:<p>Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.</p>Formula:C12H20O2Purity:98% - 99.36%Color and Shape:Physical Description Clear Colorless Liquid With An Odor Of Lavender (Ntp 1992)Molecular weight:196.29Pexidartinib
CAS:<p>Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential</p>Formula:C20H15ClF3N5Purity:98.34% - 99.45%Color and Shape:SolidMolecular weight:417.81Nutlin-3b
CAS:<p>Nutlin-3b, a less potent (+)-enantiomer of Nutlin-3, inhibits p53/MDM2 at IC50: 13.6 μM, 150x weaker than Nutlin-3a.</p>Formula:C30H30Cl2N4O4Purity:98.83%Color and Shape:SolidMolecular weight:581.492,5-dimethyl Celecoxib
CAS:<p>2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.</p>Formula:C18H16F3N3O2SPurity:99.85%Color and Shape:SolidMolecular weight:395.4Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Formula:C22H28N4O6Purity:96.29% - 98.74%Color and Shape:Blue PowderMolecular weight:444.48PS210
CAS:<p>PS210 selectively activates PDK1 (Kd: 3 μM), doesn't affect PDK1 downstream kinases. Prodrug PS423 inhibits PDK1-mediated S6K phosphorylation.</p>Formula:C19H15F3O5Purity:99.78%Color and Shape:SolidMolecular weight:380.31Obacunone
CAS:<p>Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.</p>Formula:C26H30O7Purity:98% - ≥95%Color and Shape:White PowderMolecular weight:454.51Fidaxomicin
CAS:<p>Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults.</p>Formula:C52H74Cl2O18Purity:99.76% - 99.82%Color and Shape:SolidMolecular weight:1058.04HS-173
CAS:<p>HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).</p>Formula:C21H18N4O4SPurity:99.33% - 99.64%Color and Shape:SolidMolecular weight:422.46AGK2
CAS:<p>AGK2（IC50=3.5 μM） is an effective, and specific SIRT2 inhibitor.</p>Formula:C23H13Cl2N3O2Purity:98.68% - 99.17%Color and Shape:SolidMolecular weight:434.27Loganin
CAS:<p>Loganin inhibits Cox-1, suppresses TNF-α, and has antioxidant and anti-melanogenic properties.</p>Formula:C17H26O10Purity:99.01% - >99.99%Color and Shape:White PowderMolecular weight:390.38SHR0302
CAS:<p>SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,</p>Formula:C18H22N8O2SPurity:99.11%Color and Shape:SolidMolecular weight:414.48PP121
CAS:<p>PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.</p>Formula:C17H17N7Purity:98.45% - 99.67%Color and Shape:SolidMolecular weight:319.36MK-8745
CAS:<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formula:C20H19ClFN5OSPurity:99.09% - 99.79%Color and Shape:SolidMolecular weight:431.91HS-1793
CAS:<p>HS-1793, resveratrol-like, reduces HIF-1, VEGF in hypoxia, and curbs human breast cancer growth in mouse model.</p>Formula:C16H12O3Purity:98.16% - 99.82%Color and Shape:SolidMolecular weight:252.26EPZ004777
CAS:<p>EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.</p>Formula:C28H41N7O4Purity:98.99% - 99.32%Color and Shape:SolidMolecular weight:539.67Kinsenoside
CAS:<p>Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.</p>Formula:C10H16O8Purity:99.2% - >99.99%Color and Shape:SolidMolecular weight:264.235-Geranoxy-7-methoxycoumarin
CAS:<p>5-Geranoxy-7-methoxycoumarin shows antifungal activity.</p>Formula:C20H24O4Purity:98.94% - 99.99%Color and Shape:SolidMolecular weight:328.4Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Formula:C18H19N3O3S·HClPurity:99.63% - 99.79%Color and Shape:SolidMolecular weight:393.89SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Formula:C14H8N2OPurity:97.63% - 99.82%Color and Shape:SolidMolecular weight:220.23PHA-767491 hydrochloride
CAS:<p>PHA-767491 (CAY-10572) is a potent Cdc7/CDK9 inhibitor (IC50: 10/34 nM), selective against GSK3-β, CDK1/2, CDK5, MK2, CHK2, PLK1.</p>Formula:C12H12ClN3OPurity:99.56% - 99.92%Color and Shape:SolidMolecular weight:249.69Capmatinib 2HCl
CAS:<p>Capmatinib 2HCl (INC-280 2HCl), a c-MET inhibitor, is potent (IC50 = 0.13 nM), highly specific, and induces apoptosis in tumor cells.</p>Formula:C23H19Cl2FN6OPurity:98.80%Color and Shape:SolidMolecular weight:485.34Phenazine methylsulfate
CAS:<p>Phenazine methylsulfate is anti-bacterial agents.</p>Formula:C14H14N2O4SPurity:97.67% - >99.99%Color and Shape:Yellow CrystallineMolecular weight:306.34α-Thujone
CAS:<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formula:C10H16OPurity:97.02% - 98.41%Color and Shape:Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Molecular weight:152.23CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Formula:C26H31BrN8OPurity:98.51% - 99.89%Color and Shape:SolidMolecular weight:551.48CI-1040
CAS:<p>CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).</p>Formula:C17H14ClF2IN2O2Purity:99.64%Color and Shape:Off-White To Pale Beige SolidMolecular weight:478.66SJ-172550
CAS:<p>SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).</p>Formula:C22H21ClN2O5Purity:99.87%Color and Shape:SolidMolecular weight:428.87
