Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(11 products)
- Caspase(144 products)
- FOXO1(3 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(139 products)
- PDK(9 products)
- PERK(26 products)
- Serine/threonin kinase(18 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6039 products of "Apoptosis"
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PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Formula:C18H21Cl3N4OPurity:99.5%Color and Shape:SolidMolecular weight:415.75Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurity:98.77% - 99.93%Color and Shape:White SolidMolecular weight:499.7PEAQX
CAS:<p>PEAQX (NVP-AAM077) is an oral NMDA antagonist, inhibits 1A/2A receptors (IC50: 270 nM), less so 1A/2B (IC50: 29,600 nM).</p>Formula:C17H17BrN3O5PPurity:98% - 99.9%Color and Shape:SolidMolecular weight:454.21AR42
CAS:<p>AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).</p>Formula:C18H20N2O3Purity:98.46% - 98.96%Color and Shape:SolidMolecular weight:312.36Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Formula:C26H27F4N3O7Purity:98.13% - 99%Color and Shape:SolidMolecular weight:569.5Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purity:98% - 99.88%Color and Shape:Yellow Crystalline PowderMolecular weight:232.361400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Formula:C10H17Cl2N3Purity:98% - 99.94%Color and Shape:SolidMolecular weight:250.17Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Formula:C15H18O8Purity:98.81% - 99.92%Color and Shape:White SolidMolecular weight:326.30Ipatasertib
CAS:Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Formula:C24H32ClN5O2Purity:98.28% - 99.79%Color and Shape:SolidMolecular weight:458Sulforaphane
CAS:Sulforaphane is a natural isothiocyanate that activates Nrf2. Sulforaphane has antitumor and anti-inflammatory activities. Cost-effective and quality-assured.Formula:C6H11NOS2Purity:95% - 99.79%Color and Shape:Light Yellow LiquidMolecular weight:177.29Nω-Hydroxy-nor-L-Arginine Dihydrochloride
CAS:Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginaseFormula:C5H14Cl2N4O3Purity:99.12% - 99.84%Color and Shape:SolidMolecular weight:249.10ZZW-115 hydrochloride
CAS:ZZW-115 hydrochloride inhibits the activity of NUPR1.Formula:C24H34Cl3F3N4SPurity:99.97%Color and Shape:SolidMolecular weight:573.97Chromium picolinate
CAS:Chromium picolinate causes DNA damage and mutation. It is an activator of p38.Formula:C18H12CrN3O6Purity:99.64%Color and Shape:Violet-Red Crystalline PowderMolecular weight:418.30Thalidomide-NH-PEG1-NH2 hydrochloride
CAS:Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-Formula:C17H21ClN4O5Purity:97.13%Color and Shape:SolidMolecular weight:396.83Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purity:98.90% - 99.90%Color and Shape:White To Fainly Beige Crystalline PowderMolecular weight:250.29Thalidomide-NH-CH2-COOH
CAS:Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing aFormula:C15H13N3O6Purity:96.3800%Color and Shape:SolidMolecular weight:331.28Tetrahydroxyquinone monohydrate
CAS:<p>Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.</p>Formula:C6H6O7Color and Shape:SolidMolecular weight:190.11Apocynin
CAS:Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).Formula:C9H10O3Purity:99.71% - 99.98%Color and Shape:Yellowish To Brown PowderMolecular weight:166.17Alda-1
CAS:Alda-1 activates ALDH2*1 and ALDH2*2, permeates cells, and targets mitochondrial aldehyde dehydrogenase 2.Formula:C15H11Cl2NO3Purity:98.5% - 99.63%Color and Shape:SolidMolecular weight:324.16Metamizole magnesium
CAS:<p>Metamizole magnesium (Metamizolemagnesiumsalt) is a pain reliever, which can antispasmodic.</p>Formula:C26H32MgN6O8S2Purity:93.51%Color and Shape:SolidMolecular weight:645.01ARRY 520 hydrochloride
CAS:'ARRY 520 hydrochloride: a KSP inhibitor causing apoptosis and strong anti-proliferative effects.'Formula:C20H23ClF2N4O2SPurity:98.06% - 99.62%Color and Shape:SolidMolecular weight:456.94Eltrombopag Olamine
CAS:Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietinFormula:C29H36N6O6Purity:99.59% - 99.89%Color and Shape:SolidMolecular weight:564.63HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formula:C23H22N4O3S2Purity:99.77% - 99.86%Color and Shape:SolidMolecular weight:466.58ISRIB (trans-isomer)
CAS:ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Formula:C22H24Cl2N2O4Purity:97.86% - 99.27%Color and Shape:SolidMolecular weight:451.34Thalidomide 4-fluoride
CAS:<p>Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand.</p>Formula:C13H9FN2O4Purity:99.12%Color and Shape:SolidMolecular weight:276.22Thalidomide-O-amido-C6-NH2 hydrochloride
CAS:Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.Formula:C21H27ClN4O6Purity:97.33%Color and Shape:SolidMolecular weight:466.915CA-4948
CAS:CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.Formula:C24H25N7O5Purity:99.35% - 99.88%Color and Shape:SolidMolecular weight:491.5Tenovin-6
CAS:Tenovin-6 is a p53 transcriptional activity agonist.Formula:C25H34N4O2SPurity:98.89% - >99.99%Color and Shape:SolidMolecular weight:454.63Dacarbazine citrate
CAS:Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.Formula:C12H18N6O8Color and Shape:SolidMolecular weight:374.31FOXO4-DRI acetate
FOXO4-DRI acetate is a bioactive chemical.Formula:C36H64N14O14SPurity:99.10%Color and Shape:SolidMolecular weight:5358.06Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formula:C36H56O13Purity:99.66% - 99.74%Color and Shape:SolidMolecular weight:696.82TrxR1-IN-B19
CAS:TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stressFormula:C21H22O5Purity:98.6%Color and Shape:SolidMolecular weight:354.4Thalidomide-O-amido-C3-NH2 TFA
CAS:Thalidomide-based E3 ligase linker for PROTAC tech; cereblon ligand conjugate.Formula:C20H21F3N4O8Purity:98.47%Color and Shape:SolidMolecular weight:502.4Thalidomide-O-COOH
CAS:Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.Formula:C15H12N2O7Purity:98% - 98.29%Color and Shape:SolidMolecular weight:332.27Methoxychlor
CAS:<p>Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.</p>Formula:C16H15Cl3O2Purity:98.82% - ≥95%Color and Shape:Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfMolecular weight:345.65Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Formula:C19H22Cl2N4Color and Shape:SolidMolecular weight:377.31GSK778 hydrochloride
CAS:GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.Formula:C30H34ClN5O3Purity:97.26% - 98.35%Color and Shape:SolidMolecular weight:548.08Thalidomide-4-OH
CAS:<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Formula:C13H10N2O5Purity:99.59%Color and Shape:SolidMolecular weight:274.23Thalidomide-NH-C4-NH-Boc
CAS:Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.Formula:C22H28N4O6Purity:98.87%Color and Shape:SolidMolecular weight:444.48Difurazon hydrochloride
CAS:Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.Formula:C14H13ClN6O6Purity:98.51%Color and Shape:SolidMolecular weight:396.74Methoxyamine HCl
CAS:Methoxyamine HCl targets DNA repair sites, potentially increasing DNA breaks and enhancing alkylating agents' anti-cancer effects.Formula:CH6ClNOPurity:≥98%Color and Shape:SolidMolecular weight:83.51Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formula:C25H27N5O4Purity:99.94% - >99.99%Color and Shape:White PowderMolecular weight:461.51OICR-9429
CAS:<p>OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.</p>Formula:C29H32F3N5O3Purity:97.07% - 99.93%Color and Shape:SolidMolecular weight:555.59Thalidomide-O-amido-PEG3-C2-NH2 TFA
CAS:Synthetic E3 ligase ligand-linker, Thalidomide-O-amido-PEG3-C2-NH2 TFA, used in PROTAC with cereblon ligand and PEG.Formula:C25H31F3N4O11Purity:99.82%Color and Shape:SolidMolecular weight:620.54Bigelovin
CAS:Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.Formula:C17H20O5Purity:99.61% - 99.72%Color and Shape:SolidMolecular weight:304.34KRCA-0008
CAS:KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.Formula:C30H37ClN8O4Purity:96.19%Color and Shape:SolidMolecular weight:609.12Perhexiline
CAS:Perhexiline: oral CPT1/2 inhibitor, limits fat metabolism, crosses BBB, anti-cancer, induces liver cell apoptosis, for cancer/cardio research.Formula:C19H35NColor and Shape:SolidMolecular weight:277.49Ketorolac hemicalcium
CAS:Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.Formula:C30H24CaN2O6Color and Shape:SolidMolecular weight:548.608Thalidomide-propargyl
CAS:Thalidomide-propargyl, a Cereblon ligand, links proteins in PROTAC formation.Formula:C16H12N2O5Purity:95.14%Color and Shape:SolidMolecular weight:312.28Thalidomide-NH-C6-NH2 hydrochloride
CAS:<p>Pomalidomide-C6-NH2 HCl is a synthetic conjugate for PROTAC, combining CRBN ligand and linker.</p>Formula:C19H25ClN4O4Purity:99.27%Color and Shape:SolidMolecular weight:408.88
