Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(127 products)
- FOXO1(3 products)
- IAP(65 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(24 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(91 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5622 products of "Apoptosis"
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673-A
CAS:<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formula:C15H13NOColor and Shape:SolidMolecular weight:223.27Mcl-1 inhibitor 10
CAS:<p>Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.</p>Formula:C21H15F3O4Color and Shape:SolidMolecular weight:388.342'-Deoxyadenosine
CAS:<p>2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.</p>Formula:C10H13N5O3Purity:99.71%Color and Shape:SolidMolecular weight:251.24Anticancer agent 59
Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.Formula:C42H59NO6Color and Shape:SolidMolecular weight:673.92WJ35435
CAS:<p>WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.</p>Formula:C20H21N3O3Purity:98%Color and Shape:SolidMolecular weight:351.4MPT0B392
CAS:<p>MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.</p>Formula:C19H20N2O6SColor and Shape:SolidMolecular weight:404.44RIPK1-IN-12
CAS:<p>RIPK1-IN-12: Strong RIPK1 blocker, hinders necroptosis; EC50=1.6 nM (human), 2.9 nM (mouse).</p>Formula:C24H26N4O3SColor and Shape:SolidMolecular weight:450.55(1S,2S)-Bortezomib
CAS:(1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib.Formula:C19H25BN4O4Purity:99.6%Color and Shape:SolidMolecular weight:384.243-(3-Phenoxybenzyl)amino-β-carboline
CAS:<p>3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.</p>Formula:C24H19N3OColor and Shape:SolidMolecular weight:365.43TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formula:C17H17NOPurity:99.76%Color and Shape:SolidMolecular weight:251.322,5-Dihydroxybiphenyl
CAS:<p>2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.</p>Formula:C12H10O2Purity:99.66%Color and Shape:White To Grey-Brownish PowderMolecular weight:186.21Atopaxar Hydrobromide
CAS:Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H39BrFN3O5Purity:98%Color and Shape:SolidMolecular weight:608.54Ramentaceone
CAS:<p>Ramentaceone is an antineoplastic.</p>Formula:C11H8O3Purity:98%Color and Shape:SolidMolecular weight:188.18Anti-osteoporosis agent-1
CAS:<p>Anti-osteoporosis agent-1 (comp 4aa) is an effective RPA (replication protein A) inhibitor, demonstrating potency with an IC50 value of 18 μM [1].</p>Formula:C20H19ClN2O2Color and Shape:SolidMolecular weight:354.83HX 630
CAS:<p>RXR agonist</p>Formula:C28H27NO2SPurity:98%Color and Shape:SolidMolecular weight:441.58FW1256
CAS:FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.Formula:C12H10NOPSColor and Shape:SolidMolecular weight:247.257DG
CAS:<p>7DG is a selective inhibitor of protein kinase R (PKR).</p>Formula:C26H30O5Color and Shape:SolidMolecular weight:422.51GLUT4-IN-2
CAS:<p>GLUT4-IN-2, selective GLUT4 blocker; IC50: 6.8μM (GLUT4), 11.4μM (GLUT1). Induces apoptosis, G0/G1 arrest, has antitumor effects.</p>Formula:C17H11N3O4S2Purity:99.90%Color and Shape:SolidMolecular weight:385.42ENMD-1068 HCl
CAS:<p>ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.</p>Formula:C15H29N3O2Purity:99.91%Color and Shape:SolidMolecular weight:283.41Ethacridine
CAS:<p>Ethacridine acts as an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and functions as an activator of transcriptional coactivators. It induces apoptosis in thyroid cancer cells and promotes the differentiation of thyroid follicular cells.</p>Formula:C15H15N3OColor and Shape:SolidMolecular weight:253.30BLM-IN-1
CAS:BLM-IN-1: BLM inhibitor, KD 1.81 μM, IC50 0.95 μM; causes DNA damage, apoptosis, stops cancer cell growth.Formula:C28H35FN4OColor and Shape:SolidMolecular weight:462.6(S)-Elobixibat
CAS:<p>(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.</p>Formula:C36H45N3O7S2Color and Shape:SolidMolecular weight:695.89STK17A/B-IN-1
CAS:<p>STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective inhibitor of STK17A/B, demonstrating an IC50 of 23 nM for STK17A. This compound is utilized in tumor research.</p>Formula:C26H27N7OColor and Shape:SolidMolecular weight:453.54UCD38B HCl
CAS:<p>UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.</p>Formula:C15H17Cl2N7O3Purity:98%Color and Shape:SolidMolecular weight:414.25SS28
CAS:<p>SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.</p>Formula:C18H20O3Purity:98%Color and Shape:SolidMolecular weight:284.35Anti-melanoma agent 1
CAS:<p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>Formula:C28H28N2O2Color and Shape:SolidMolecular weight:424.535HPP-33
CAS:5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.Formula:C20H21NO3Color and Shape:SolidMolecular weight:323.39MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Formula:C35H49F2N7O4Purity:98.77% - 99.99%Color and Shape:SolidMolecular weight:669.8ARP 101
CAS:<p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>Formula:C20H26N2O5SPurity:98.26%Color and Shape:SolidMolecular weight:406.5Caspase-3-IN-1
CAS:<p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>Formula:C26H25N3O6SColor and Shape:SolidMolecular weight:507.56Epinephrine bitartrate
CAS:<p>L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.</p>Formula:C13H19NO9Purity:98.6% - 99.07%Color and Shape:White SolidMolecular weight:333.3Pracinostat dihydrochloride
CAS:<p>Pracinostat dihydrochloride is a highly effective histone deacetylase (HDAC) inhibitor with IC₅₀ values ranging from 40 to 140 nM, utilized in cancer research. Additionally, it inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC₅₀ of less than 10 nM.</p>Formula:C20H32Cl2N4O2Color and Shape:SolidMolecular weight:431.40PD-1/PD-L1-IN-28
CAS:<p>PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.</p>Formula:C24H24N4O2Color and Shape:SolidMolecular weight:400.47HBV-IN-23
CAS:<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Formula:C25H27N3O3SColor and Shape:SolidMolecular weight:449.57SID 3712249
CAS:<p>SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).</p>Formula:C17H21N7Purity:98%Color and Shape:SolidMolecular weight:323.4Selicrelumab
CAS:<p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>Purity:98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Color and Shape:LiquidSKI-I
CAS:<p>SKI-I: Human sphingosine kinase inhibitor, IC50 1.2μM; hERK2 inhibitor, IC50 11μM; promotes tumor cell apoptosis.</p>Formula:C25H18N4O2Color and Shape:SolidMolecular weight:406.44HDACs/mTOR Inhibitor 1
CAS:<p>HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,</p>Formula:C28H38N8O5Color and Shape:SolidMolecular weight:566.65Ro 31-7837
CAS:<p>Ro 31-7837 is an opener of potassium channel.</p>Formula:C17H16N2O2Color and Shape:SolidMolecular weight:280.32EAPB 02303
CAS:<p>EAPB 02303, a microtubule inhibitor, induces mitotic arrest, spindle impairment, apoptosis, and has antitumor effects, enhancing Paclitaxel.</p>Formula:C17H14N4O2Color and Shape:SolidMolecular weight:306.32RDR03871
CAS:<p>RDR03871 is an MDM2 inhibitor.</p>Formula:C18H16ClF3N6Purity:97.78%Color and Shape:SolidMolecular weight:408.81Nec-3a
CAS:<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Formula:C21H18F4N2O4Color and Shape:SolidMolecular weight:438.37Anti-inflammatory agent 17
CAS:<p>Compound 17: Orally active, potent IL-6 & TNF-α inhibitor; not cytotoxic; promising for ALI research.</p>Formula:C20H23NO5Color and Shape:SolidMolecular weight:357.4IM-54
CAS:<p>IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.</p>Formula:C19H23N3O2Purity:99.24%Color and Shape:SolidMolecular weight:325.4RIP1 kinase inhibitor 5
CAS:<p>RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) in</p>Formula:C13H17F2NO2Purity:98%Color and Shape:SolidMolecular weight:257.28HS-438
CAS:<p>HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.</p>Formula:C17H17N3O3SColor and Shape:SolidMolecular weight:343.4RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Formula:C32H33FN6O4Color and Shape:SolidMolecular weight:584.64MDM2/XIAP-IN-2
CAS:<p>MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).</p>Formula:C29H32N2O4SColor and Shape:SolidMolecular weight:504.64KRC-108
CAS:<p>KRC-108 is a potent kinase inhibitor targeting Ron, Flt3, TrkA, and c-Met with strong anti-proliferative effects on various cancer cells.</p>Formula:C20H20N6OColor and Shape:SolidMolecular weight:360.41ACA-28
CAS:<p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>Formula:C17H16O6Purity:98.73%Color and Shape:SolidMolecular weight:316.31
