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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5622 products of "Apoptosis"

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  • Ivaltinostat
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    Ivaltinostat

    CAS:
    <p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>
    Formula:C24H33N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:427.54

    Ref: TM-T14936

  • Ceranib-2
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    Ceranib-2

    CAS:
    <p>Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.</p>
    Formula:C25H19NO3
    Purity:98.49%
    Color and Shape:Solid
    Molecular weight:381.42

    Ref: TM-T10761

  • RET-IN-6
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    RET-IN-6

    CAS:
    <p>RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).</p>
    Formula:C30H29N7
    Color and Shape:Solid
    Molecular weight:487.6

    Ref: TM-T63249

  • LOM612
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    LOM612

    CAS:
    LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.
    Formula:C13H10N2O2S
    Color and Shape:Solid
    Molecular weight:258.3

    Ref: TM-T19405

  • p53 Activator 5
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    p53 Activator 5

    CAS:
    <p>Potent p53 Activator 5, SC150 &lt;0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>
    Formula:C29H32F6N4O
    Color and Shape:Solid
    Molecular weight:566.58

    Ref: TM-T72770

  • Erbstatin
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    Erbstatin

    CAS:
    <p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>
    Formula:C9H9NO3
    Color and Shape:Solid
    Molecular weight:179.17

    Ref: TM-T24039

  • Cinnabarinic acid
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    Cinnabarinic acid

    CAS:
    <p>mGlu4 receptor agonist</p>
    Formula:C14H8N2O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:300.22

    Ref: TM-T22669

  • BI-0282
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    BI-0282

    CAS:
    <p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>
    Formula:C30H23Cl2FN4O4
    Color and Shape:Solid
    Molecular weight:593.43

    Ref: TM-T64196

  • MI-192
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    MI-192

    CAS:
    <p>MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.</p>
    Formula:C24H21N3O2
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T21898

  • PI3K/Akt/mTOR-IN-3
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    PI3K/Akt/mTOR-IN-3

    CAS:
    <p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>
    Formula:C34H51NO2
    Color and Shape:Solid
    Molecular weight:505.77

    Ref: TM-T63455

  • MMP2-IN-1
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    MMP2-IN-1

    CAS:
    MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.
    Formula:C15H13NO5S
    Color and Shape:Solid
    Molecular weight:319.33

    Ref: TM-T60845

  • RDR03871
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    RDR03871

    CAS:
    <p>RDR03871 is an MDM2 inhibitor.</p>
    Formula:C18H16ClF3N6
    Purity:97.78%
    Color and Shape:Solid
    Molecular weight:408.81

    Ref: TM-T28509

  • Imofinostat
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    Imofinostat

    CAS:
    Imofinostat (MPT0E028) is a selective, orally available pan-HDAC inhibitor with IC₅₀ values of 53.0/106.2/29.5 nM against HDAC1/HDAC2/HDAC6 in HCT116 cells.
    Formula:C17H16N2O4S
    Color and Shape:Solid
    Molecular weight:344.38

    Ref: TM-T16131

  • VEGFR-2-IN-19
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    VEGFR-2-IN-19

    CAS:
    <p>VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.</p>
    Formula:C21H19N3O2
    Color and Shape:Solid
    Molecular weight:345.39

    Ref: TM-T61137

  • Caylin-2
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    Caylin-2

    CAS:
    <p>Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.</p>
    Formula:C32H30F6N4O4
    Color and Shape:Solid
    Molecular weight:648.6

    Ref: TM-T36465

  • SMI-6860766
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    SMI-6860766

    CAS:
    <p>SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.</p>
    Formula:C15H11BrClNO
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.61

    Ref: TM-T24808

  • Quinidine polygalacturonate
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    Quinidine polygalacturonate

    CAS:
    Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.
    Formula:C26H34N2O9
    Color and Shape:Solid
    Molecular weight:518.22643

    Ref: TM-T64286

  • RO2468
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    RO2468

    CAS:
    <p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>
    Formula:C30H30Cl2FN5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:614.49

    Ref: TM-T24719

  • Merck-22-6
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    Merck-22-6

    CAS:
    <p>Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.</p>
    Formula:C40H43N7O2
    Color and Shape:Solid
    Molecular weight:653.82

    Ref: TM-T25791

  • Topoisomerase II inhibitor 3
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    Topoisomerase II inhibitor 3

    CAS:
    <p>Acridone-based Topoisomerase II inhibitor 3 targets topo IIα/β (IC50: 0.17μM α, 0.23μM β), causes DNA damage, and induces apoptosis.</p>
    Formula:C18H20N4O4
    Color and Shape:Solid
    Molecular weight:356.38

    Ref: TM-T61283

  • TH-Z835
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    TH-Z835

    CAS:
    <p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>
    Formula:C30H38N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:498.66

    Ref: TM-T78661

  • CCT373567
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    CCT373567

    CAS:
    <p>CCT373567 is a potent degrader of the transcriptional repressor BCL6 (IC50: 2.9 nM) and exhibits anti-proliferative effects.</p>
    Formula:C26H29ClF2N6O3
    Color and Shape:Solid
    Molecular weight:547

    Ref: TM-T63862

  • Antitumor agent-70
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    Antitumor agent-70

    CAS:
    <p>Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.</p>
    Formula:C21H18N4O2
    Color and Shape:Solid
    Molecular weight:358.39

    Ref: TM-T61313

  • ZC0101
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    ZC0101

    CAS:
    <p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>
    Formula:C17H15N3O2
    Color and Shape:Solid
    Molecular weight:293.32

    Ref: TM-T60618

  • SK-7041
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    SK-7041

    CAS:
    <p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>
    Formula:C19H21N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:339.39

    Ref: TM-T24798

  • Nampt-IN-3
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    Nampt-IN-3

    CAS:
    <p>Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).</p>
    Formula:C29H25N7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:503.55

    Ref: TM-T13792

  • OT-82
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    OT-82

    CAS:
    OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.
    Formula:C26H21FN4O
    Purity:98.91% - 99.315%
    Color and Shape:Solid
    Molecular weight:424.47

    Ref: TM-T12330

  • Methylisothiazolinone
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    Methylisothiazolinone

    CAS:
    <p>Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.</p>
    Formula:C4H5NOS
    Purity:99.78%
    Color and Shape:Colorless Prisms Liquid
    Molecular weight:115.15

    Ref: TM-T19774

  • RET-IN-22
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    RET-IN-22

    CAS:
    <p>RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-</p>
    Formula:C29H31F3N6O4
    Color and Shape:Solid
    Molecular weight:584.59

    Ref: TM-T78683

  • ZT55
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    ZT55

    CAS:
    <p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>
    Formula:C17H16N2O3
    Color and Shape:Solid
    Molecular weight:296.32

    Ref: TM-T73567

  • DRI-C25441
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    DRI-C25441

    CAS:
    <p>DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered</p>
    Formula:C31H21N3O6
    Color and Shape:Solid
    Molecular weight:531.51

    Ref: TM-T79194

  • Anticancer agent 58
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    Anticancer agent 58

    <p>Anticancer agent 58 targets A549/T24 cell lines; IC50: 0.6/0.7 μM. It triggers apoptosis, ups Ca2+/ROS, and lowers mitochondrial potential.</p>
    Formula:C39H55NO5
    Color and Shape:Solid
    Molecular weight:617.86

    Ref: TM-T72475

  • S130
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    S130

    CAS:
    S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.
    Formula:C24H25N3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:387.47

    Ref: TM-T12819

  • EGFR-IN-60
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    EGFR-IN-60

    CAS:
    <p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>
    Formula:C28H28Cl2N6O
    Color and Shape:Solid
    Molecular weight:535.47

    Ref: TM-T63769

  • PI3Kδ/γ-IN-3
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    PI3Kδ/γ-IN-3

    CAS:
    <p>PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM).</p>
    Formula:C23H20ClN9O
    Color and Shape:Solid
    Molecular weight:473.92

    Ref: TM-T63078

  • Alteminostat
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    Alteminostat

    CAS:
    <p>Alteminostat is used as a histone deacetylase inhibitor and is an antineoplastic drug candidate.</p>
    Formula:C27H36N6O3
    Color and Shape:Solid
    Molecular weight:492.61

    Ref: TM-T25059

  • Topoisomerase II inhibitor 10
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    Topoisomerase II inhibitor 10

    CAS:
    <p>Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM).</p>
    Formula:C27H20N6O7S
    Color and Shape:Solid
    Molecular weight:572.55

    Ref: TM-T64047

  • BMS-200
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    BMS-200

    CAS:
    BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.
    Formula:C27H27F2NO6
    Color and Shape:Solid
    Molecular weight:499.5

    Ref: TM-T70285

  • DBIBB
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    DBIBB

    CAS:
    <p>DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.</p>
    Formula:C23H20N2O6S
    Purity:98.49% - 99.1%
    Color and Shape:Solid
    Molecular weight:452.48

    Ref: TM-T22070

  • DMH2
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    DMH2

    CAS:
    <p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>
    Formula:C27H25N5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:451.52

    Ref: TM-T25346

  • CymitQuimica logo
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    SZM-1209

    CAS:
    <p>SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.</p>
    Formula:C31H29F5N4O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:696.71

    Ref: TM-T73382

  • EP12
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    EP12

    CAS:
    <p>EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by</p>
    Formula:C26H22FN3O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:427.47

    Ref: TM-T78846

  • BLM-IN-2
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    BLM-IN-2

    <p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>
    Formula:C33H38BrFN4O
    Color and Shape:Solid
    Molecular weight:605.58

    Ref: TM-T73391

  • BMS-1166 hydrochloride
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    BMS-1166 hydrochloride

    CAS:
    <p>"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."</p>
    Formula:C36H34Cl2N2O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:677.57

    Ref: TM-T14670

  • APPA
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    APPA

    CAS:
    <p>APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of</p>
    Formula:C14H13NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:243.26

    Ref: TM-T78612

  • PD-1/PD-L1-IN 5
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    PD-1/PD-L1-IN 5

    CAS:
    <p>PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).</p>
    Formula:C22H18N4O3S
    Color and Shape:Solid
    Molecular weight:418.47

    Ref: TM-T62193

  • SIRT6 activator 12q
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    SIRT6 activator 12q

    CAS:
    <p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>
    Formula:C31H22N2O2
    Color and Shape:Solid
    Molecular weight:454.52

    Ref: TM-T72484

  • Ac-​IETD-​CHO
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    Ac-​IETD-​CHO

    CAS:
    <p>Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.</p>
    Formula:C21H34N4O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:502.52

    Ref: TM-T78586

  • CEP-1612
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    CEP-1612

    CAS:
    <p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>
    Formula:C35H53N7O7
    Color and Shape:Solid
    Molecular weight:683.84

    Ref: TM-T30795

  • SKLB0565
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    SKLB0565

    CAS:
    <p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>
    Formula:C20H25ClN6O
    Color and Shape:Solid
    Molecular weight:400.91

    Ref: TM-T61942