Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(127 products)
- FOXO1(3 products)
- IAP(65 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(24 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(91 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5622 products of "Apoptosis"
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DC-5163
CAS:<p>DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.</p>Formula:C18H20ClN3OSPurity:98%Color and Shape:SolidMolecular weight:361.89Topoisomerase II inhibitor 9
CAS:<p>Topoisomerase II inhibitor 9: Topo II blocker (IC50: 0.97 μM), DNA intercalator (IC50: 43.51 μM), arrests G2/M in Hep G-2 cells and triggers apoptosis.</p>Formula:C22H17N7O3S2Color and Shape:SolidMolecular weight:491.55Caylin-2
CAS:<p>Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.</p>Formula:C32H30F6N4O4Color and Shape:SolidMolecular weight:648.6c-Met-IN-9
CAS:<p>c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.</p>Formula:C25H19F2N5O3Color and Shape:SolidMolecular weight:475.45B-Raf IN 9
CAS:<p>B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).</p>Formula:C23H20N4OSColor and Shape:SolidMolecular weight:400.5PI3Kα-IN-7
CAS:<p>PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.</p>Formula:C17H22N8O2SColor and Shape:SolidMolecular weight:402.47IM-54
CAS:<p>IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.</p>Formula:C19H23N3O2Purity:99.24%Color and Shape:SolidMolecular weight:325.4HDAC1/6-IN-1
CAS:<p>HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.</p>Formula:C32H45N7O4Color and Shape:SolidMolecular weight:591.74AD-2646
CAS:<p>AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.</p>Formula:C23H40N2O4Color and Shape:SolidMolecular weight:408.57NSC260594
CAS:<p>NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-</p>Formula:C29H24N6O3Color and Shape:SolidMolecular weight:504.54Trehalose 6-behenate
CAS:<p>Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.</p>Formula:C34H64O12Purity:98%Color and Shape:SolidMolecular weight:664.86AV123
CAS:AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.Formula:C11H14N4O2Color and Shape:SolidMolecular weight:234.25Dipin
CAS:<p>Dipin is an Antineoplastic.</p>Formula:C12H24N6O2P2Purity:98%Color and Shape:SolidMolecular weight:346.31MCL-1/BCL-2-IN-3
CAS:MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.Formula:C27H25BrN2O5SColor and Shape:SolidMolecular weight:569.47pan-HER-IN-1
CAS:<p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>Formula:C19H14BrN5OColor and Shape:SolidMolecular weight:408.25HMBPP triammonium
CAS:<p>HMBPP triammonium is a stimulator of gamma delta T cells.</p>Formula:C5H15NO8P2Color and Shape:SolidMolecular weight:279.122MpsBAY2a
CAS:<p>carcinoma cell proliferation.</p>Formula:C29H28N6OPurity:98%Color and Shape:SolidMolecular weight:476.57MBC-11
CAS:MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.Formula:C11H20N3O14P3Purity:>99.99% - >99.99%Color and Shape:SolidMolecular weight:511.21YH-306
CAS:<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Formula:C19H18N2O2Purity:98.06%Color and Shape:SolidMolecular weight:306.36MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Formula:C23H21Cl2FN2O3Color and Shape:SolidMolecular weight:463.33TH1834 dihydrochloride
CAS:<p>TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.</p>Formula:C33H42Cl2N6O3Purity:98%Color and Shape:SolidMolecular weight:641.63AK301
CAS:AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).Formula:C19H21ClN2O2Purity:99.75%Color and Shape:SolidMolecular weight:344.84Antitumor agent-19
CAS:<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Formula:C24H21ClF3N5OPurity:98.95% - 99.38%Color and Shape:SolidMolecular weight:487.9Bcl-2/Mcl-1-IN-2
CAS:<p>Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.</p>Formula:C26H24ClNO3Color and Shape:SolidMolecular weight:433.93PI3K/Akt/mTOR-IN-3
CAS:<p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>Formula:C34H51NO2Color and Shape:SolidMolecular weight:505.77GDP366
CAS:<p>GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.</p>Formula:C20H17N5OSPurity:98.78% - 99.84%Color and Shape:SolidMolecular weight:375.45BI-0282
CAS:<p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>Formula:C30H23Cl2FN4O4Color and Shape:SolidMolecular weight:593.43Mcl1-IN-9
CAS:<p>Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.</p>Formula:C37H39ClN4O4Purity:98%Color and Shape:SolidMolecular weight:639.18MBM-17
CAS:<p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>Formula:C28H28N6O2Purity:98%Color and Shape:SolidMolecular weight:480.56Erbstatin
CAS:<p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>Formula:C9H9NO3Color and Shape:SolidMolecular weight:179.17BS-181
CAS:BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.Formula:C22H32N6Purity:98%Color and Shape:SolidMolecular weight:380.53A-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Formula:C16H26N4O3Purity:96.29%Color and Shape:SolidMolecular weight:322.4LOM612
CAS:LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.Formula:C13H10N2O2SColor and Shape:SolidMolecular weight:258.3Se-Methylselenocysteine hydrochloride
CAS:<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Formula:C4H10ClNO2SePurity:98%Color and Shape:SolidMolecular weight:218.54(5Z,2E)-CU-3
CAS:<p>(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mM</p>Formula:C16H12N2O4S3Purity:99.02%Color and Shape:SolidMolecular weight:392.47USP7-IN-4
CAS:<p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>Formula:C29H34N6O3Purity:98.27% - 99.09%Color and Shape:SolidMolecular weight:514.62NSC405640
CAS:<p>NSC405640 selectively inhibits MDM2-p53 interaction, restoring mutated p53 structure; halts growth of cells with normal p53. [1]</p>Formula:C12H10Cl2SnColor and Shape:SolidMolecular weight:343.82Sparfosic Acid
CAS:<p>Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma</p>Formula:C6H10NO8PPurity:98.89%Color and Shape:SolidMolecular weight:255.12FKGK 18
CAS:<p>FKGK 18: GVIA iPLA2 inhibitor, 99.9% at 0.091 fraction, selective, IC50 ~50 nM–3 μM, reduces blood glucose and diabetes in NOD mice.</p>Formula:C16H15F3OColor and Shape:SolidMolecular weight:280.28ICG-001
CAS:<p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Formula:C33H32N4O4Purity:99.55% - 99.62%Color and Shape:SolidMolecular weight:548.63ML132
CAS:<p>ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).</p>Formula:C22H28ClN5O5Color and Shape:SolidMolecular weight:477.94GZD856
CAS:GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.Formula:C29H27F3N6OPurity:98%Color and Shape:SolidMolecular weight:532.56Docetaxel trihydrate
CAS:Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis.Formula:C43H59NO17Purity:98.68% - >99.99%Color and Shape:White Crystalline PowderMolecular weight:861.95KS106
CAS:<p>KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.</p>Formula:C18H15BrF3N3O2SPurity:99.31%Color and Shape:SolidMolecular weight:474.3ARP 101
CAS:<p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>Formula:C20H26N2O5SPurity:98.26%Color and Shape:SolidMolecular weight:406.5GL-331
CAS:<p>GL-331, a DNA topoisomerase II inhibitor, is used potentially for the treatment of small cell lung cancer and gastric cancer.</p>Formula:C27H24N2O9Color and Shape:SolidMolecular weight:520.49KY1022
CAS:<p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>Formula:C17H19N3OSColor and Shape:SolidMolecular weight:313.42VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Formula:C26H20Cl2F3N5O3S2Color and Shape:SolidMolecular weight:642.5Apoptotic agent-1
CAS:<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Formula:C12H6ClN5O2SColor and Shape:SolidMolecular weight:319.73LG190178
CAS:<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Formula:C28H42O5Color and Shape:SolidMolecular weight:458.63
