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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 5622 products of "Apoptosis"

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  • CEP-1612
    Targetmol
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    CEP-1612

    CAS:
    <p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>
    Formula:C35H53N7O7
    Color and Shape:Solid
    Molecular weight:683.84

    Ref: TM-T30795

  • SIRT6 activator 12q
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    SIRT6 activator 12q

    CAS:
    <p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>
    Formula:C31H22N2O2
    Color and Shape:Solid
    Molecular weight:454.52

    Ref: TM-T72484

  • BLM-IN-2
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    BLM-IN-2

    <p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>
    Formula:C33H38BrFN4O
    Color and Shape:Solid
    Molecular weight:605.58

    Ref: TM-T73391

  • Autophagy-IN-2
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    Autophagy-IN-2

    CAS:
    <p>Autophagy-IN-2 (7h) blocks autophagic flux, triggers cancer cell death, aids in triple-negative breast cancer study.</p>
    Formula:C17H19N5O
    Color and Shape:Solid
    Molecular weight:309.37

    Ref: TM-T60749

  • EGFR-IN-60
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    EGFR-IN-60

    CAS:
    <p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>
    Formula:C28H28Cl2N6O
    Color and Shape:Solid
    Molecular weight:535.47

    Ref: TM-T63769

  • Benpyrine
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    Benpyrine

    CAS:
    Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.
    Formula:C16H16N6O
    Color and Shape:Solid
    Molecular weight:308.34

    Ref: TM-T36486

  • HLI 373
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    HLI 373

    CAS:
    <p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>
    Formula:C18H23N5O2
    Color and Shape:Solid
    Molecular weight:341.41

    Ref: TM-T22087

  • Antioxidant agent-5
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    Antioxidant agent-5

    CAS:
    <p>Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.</p>
    Formula:C24H24N6O
    Color and Shape:Solid
    Molecular weight:412.49

    Ref: TM-T62111

  • Caspase-9 Inhibitor III
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    Caspase-9 Inhibitor III

    CAS:
    <p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>
    Formula:C24H35ClN6O9
    Color and Shape:Solid
    Molecular weight:587.02

    Ref: TM-T72281

  • LLP-3
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    LLP-3

    CAS:
    <p>Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.</p>
    Formula:C32H23ClN2O4
    Color and Shape:Solid
    Molecular weight:534.99

    Ref: TM-T35542

  • c-Met-IN-14
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    c-Met-IN-14

    CAS:
    <p>c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.</p>
    Formula:C34H38ClFN4O7S
    Color and Shape:Solid
    Molecular weight:701.2

    Ref: TM-T73022

  • Anticancer agent 83
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    Anticancer agent 83

    CAS:
    <p>Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.</p>
    Formula:C20H19N5OS
    Color and Shape:Solid
    Molecular weight:377.46

    Ref: TM-T61576

  • Cadein1
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    Cadein1

    <p>Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.</p>
    Formula:C33H48F2INO2
    Color and Shape:Solid
    Molecular weight:655.64

    Ref: TM-T73413

  • BMS-37
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    BMS-37

    CAS:
    <p>BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.</p>
    Formula:C27H32N2O4
    Color and Shape:Solid
    Molecular weight:448.55

    Ref: TM-T70286

  • GEM144
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    GEM144

    CAS:
    <p>GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.</p>
    Formula:C28H31NO5
    Color and Shape:Solid
    Molecular weight:461.55

    Ref: TM-T62916

  • ATSP-7041
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    ATSP-7041

    CAS:
    <p>ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)</p>
    Formula:C87H125N17O21
    Color and Shape:Solid
    Molecular weight:1745.02

    Ref: TM-T70611

  • Se-Methylselenocysteine hydrochloride
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    Se-Methylselenocysteine hydrochloride

    CAS:
    <p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>
    Formula:C4H10ClNO2Se
    Purity:98%
    Color and Shape:Solid
    Molecular weight:218.54

    Ref: TM-T78587

  • (S)-PERK-IN-5
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    (S)-PERK-IN-5

    CAS:
    <p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>
    Formula:C25H26F2N4O3
    Color and Shape:Solid
    Molecular weight:468.5

    Ref: TM-T63007

  • PI3Kδ-IN-10
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    PI3Kδ-IN-10

    CAS:
    <p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>
    Formula:C19H16ClN9
    Color and Shape:Solid
    Molecular weight:405.84

    Ref: TM-T62013

  • Topoisomerase I inhibitor 3
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    Topoisomerase I inhibitor 3

    CAS:
    <p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>
    Formula:C18H14FNO3
    Color and Shape:Solid
    Molecular weight:311.31

    Ref: TM-T60766

  • Aurora kinase-IN-1
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    Aurora kinase-IN-1

    <p>Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.</p>
    Formula:C30H25Br2N3O5
    Color and Shape:Solid
    Molecular weight:667.34

    Ref: TM-T72522

  • p53 Activator 2
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    p53 Activator 2

    CAS:
    <p>p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.</p>
    Formula:C20H21N5O2
    Color and Shape:Solid
    Molecular weight:363.41

    Ref: TM-T61369

  • TrxR inhibitor D9
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    TrxR inhibitor D9

    CAS:
    <p>TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).</p>
    Formula:C25H20AuOPS
    Color and Shape:Solid
    Molecular weight:596.43

    Ref: TM-T29018

  • DAT-230
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    DAT-230

    CAS:
    <p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>
    Formula:C20H21NO2S
    Color and Shape:Solid
    Molecular weight:339.45

    Ref: TM-T70527

  • Apoptotic agent-3
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    Apoptotic agent-3

    CAS:
    <p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>
    Formula:C31H21N5OS
    Color and Shape:Solid
    Molecular weight:511.6

    Ref: TM-T63530

  • CCT373566
    Targetmol
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    CCT373566

    CAS:
    <p>CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro &amp; shrinks tumors in vivo.</p>
    Formula:C26H29ClF2N6O3
    Color and Shape:Solid
    Molecular weight:547

    Ref: TM-T63861

  • YLT205
    Targetmol
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    YLT205

    CAS:
    <p>YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.</p>
    Formula:C16H12BrClN4O2S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:471.78

    Ref: TM-T24660

  • RDR03871
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    RDR03871

    CAS:
    <p>RDR03871 is an MDM2 inhibitor.</p>
    Formula:C18H16ClF3N6
    Purity:97.78%
    Color and Shape:Solid
    Molecular weight:408.81

    Ref: TM-T28509

  • MDM2-p53-IN-16
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    MDM2-p53-IN-16

    CAS:
    <p>MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.</p>
    Formula:C32H33N3O5
    Color and Shape:Solid
    Molecular weight:539.62

    Ref: TM-T72832

  • Ferroptosis inducer-1
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    Ferroptosis inducer-1

    CAS:
    <p>Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .</p>
    Formula:C25H21ClN2O5
    Color and Shape:Solid
    Molecular weight:464.9

    Ref: TM-T72403

  • Anti-melanoma agent 1
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    Anti-melanoma agent 1

    CAS:
    <p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>
    Formula:C28H28N2O2
    Color and Shape:Solid
    Molecular weight:424.53

    Ref: TM-T62291

  • UCD38B HCl
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    UCD38B HCl

    CAS:
    <p>UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.</p>
    Formula:C15H17Cl2N7O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:414.25

    Ref: TM-T24920

  • HX 630
    Targetmol
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    HX 630

    CAS:
    <p>RXR agonist</p>
    Formula:C28H27NO2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:441.58

    Ref: TM-T22844

  • TRAF-STOP inhibitor 6877002
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    TRAF-STOP inhibitor 6877002

    CAS:
    <p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>
    Formula:C17H17NO
    Purity:99.76%
    Color and Shape:Solid
    Molecular weight:251.32

    Ref: TM-T17157

  • (1S,2S)-Bortezomib
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    (1S,2S)-Bortezomib

    CAS:
    (1S,2S)-Bortezomib (Bortezomib) is an enantiomer of Bortezomib.
    Formula:C19H25BN4O4
    Purity:99.6%
    Color and Shape:Solid
    Molecular weight:384.24

    Ref: TM-T10061

  • PARP1-IN-10
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    PARP1-IN-10

    CAS:
    <p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>
    Formula:C20H23N3O5
    Color and Shape:Solid
    Molecular weight:385.41

    Ref: TM-T61694

  • Nevanimibe
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    Nevanimibe

    CAS:
    <p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>
    Formula:C27H39N3O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.62

    Ref: TM-T12225

  • Apoptosis inducer 6
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    Apoptosis inducer 6

    CAS:
    <p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>
    Formula:C27H26N4O3S
    Color and Shape:Solid
    Molecular weight:486.59

    Ref: TM-T63232

  • HMBPP triammonium
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    HMBPP triammonium

    CAS:
    <p>HMBPP triammonium is a stimulator of gamma delta T cells.</p>
    Formula:C5H15NO8P2
    Color and Shape:Solid
    Molecular weight:279.122

    Ref: TM-T32087

  • Obatoclax
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    Obatoclax

    CAS:
    <p>Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.</p>
    Formula:C20H19N3O
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:317.38

    Ref: TM-T41278

  • HDAC-IN-51
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    HDAC-IN-51

    <p>HDAC-IN-51 is an HDAC inhibitor.</p>
    Formula:C27H24N4O2
    Purity:97.19%
    Color and Shape:Solid
    Molecular weight:436.51

    Ref: TM-T73181

  • MX107
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    MX107

    CAS:
    <p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>
    Formula:C24H28N2O2
    Color and Shape:Solid
    Molecular weight:376.49

    Ref: TM-T69845

  • CT1-3
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    CT1-3

    CAS:
    <p>CT1-3 is a potent anti-cancer compound targeting JNK/Bcl-2 pathways, blocking EMT in HCCs, and is non-toxic to liver/kidneys in mice.</p>
    Formula:C25H29NO3S2
    Color and Shape:Solid
    Molecular weight:455.63

    Ref: TM-T62822

  • YH-306
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    YH-306

    CAS:
    <p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>
    Formula:C19H18N2O2
    Purity:98.06%
    Color and Shape:Solid
    Molecular weight:306.36

    Ref: TM-T24642

  • PC-046
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    PC-046

    CAS:
    <p>PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).</p>
    Formula:C22H18N2O3
    Color and Shape:Solid
    Molecular weight:358.39

    Ref: TM-T71252

  • Tubulin inhibitor 23
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    Tubulin inhibitor 23

    CAS:
    <p>Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.</p>
    Formula:C26H23NO6S
    Color and Shape:Solid
    Molecular weight:477.53

    Ref: TM-T63120

  • CAY10682
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    CAY10682

    CAS:
    <p>(±)-Nutlin-3 &amp; CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>
    Formula:C30H25BrFN5O
    Color and Shape:Solid
    Molecular weight:570.45

    Ref: TM-T36192

  • n-Octyl caffeate
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    n-Octyl caffeate

    CAS:
    <p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>
    Formula:C17H24O4
    Color and Shape:Solid
    Molecular weight:292.37

    Ref: TM-T72740

  • Rohinitib
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    Rohinitib

    CAS:
    <p>Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.</p>
    Formula:C29H31NO8
    Color and Shape:Solid
    Molecular weight:521.56

    Ref: TM-T71395

  • SCAL-255
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    SCAL-255

    CAS:
    <p>SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.</p>
    Formula:C27H28F3N5O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:527.54

    Ref: TM-T79476