Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5600 products of "Apoptosis"
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A09-003
CAS:<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Formula:C23H26N4OPurity:99.61%Color and Shape:SolidMolecular weight:374.48CP 461
CAS:<p>CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.</p>Formula:C25H22ClFN2OPurity:99.82%Color and Shape:SolidMolecular weight:420.91LQZ-7F
CAS:<p>LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.</p>Formula:C14H7N9O3Purity:98.64%Color and Shape:SolidMolecular weight:349.26Vamotinib
CAS:<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Formula:C29H27F3N6OPurity:99.64%Color and Shape:SolidMolecular weight:532.56RIPK3-IN-1
CAS:<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Formula:C29H25FN4O4Purity:98.27%Color and Shape:SolidMolecular weight:512.53Cot inhibitor-1
CAS:<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Formula:C27H27Cl2FN8Purity:98.59%Color and Shape:SolidMolecular weight:553.46Triparanol
CAS:<p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>Formula:C27H32ClNO2Purity:99.72%Color and Shape:SolidMolecular weight:438NecroX-7
CAS:<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Formula:C24H29N3O3SPurity:98.22%Color and Shape:SolidMolecular weight:439.57Imipramine
CAS:<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Formula:C19H24N2Purity:99.4%Color and Shape:White To Off-White /Hydrochloride/ SolidMolecular weight:280.41HBED
CAS:<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formula:C20H24N2O6Purity:97.35% - 98.58%Color and Shape:SolidMolecular weight:388.41Triciribine phosphate
CAS:<p>Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.</p>Formula:C13H17N6O7PPurity:97.94%Color and Shape:SolidMolecular weight:400.28LCS3
CAS:<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Formula:C11H7ClN2O4Purity:99.68%Color and Shape:SolidMolecular weight:266.64TAI-1
CAS:<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Formula:C24H21N3O3SPurity:99.58%Color and Shape:SolidMolecular weight:431.51Apostatin-1
CAS:<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Formula:C19H27N3OSPurity:99.31%Color and Shape:SolidMolecular weight:345.5BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formula:C23H19Cl2N3OSPurity:99.49%Color and Shape:SolidMolecular weight:456.39Alethine
CAS:<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Formula:C10H22N4O2S2Purity:98.83%Color and Shape:SolidMolecular weight:294.44TC-DAPK 6
CAS:<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Formula:C17H12N2O2Purity:98.73%Color and Shape:SolidMolecular weight:276.29MMRi64
CAS:<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Formula:C22H17Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:410.3VAS 3947
CAS:<p>VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.</p>Formula:C14H10N6OSPurity:98.44%Color and Shape:SolidMolecular weight:310.33CBS9106
CAS:<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Formula:C18H21ClF3N3O3Purity:98.98%Color and Shape:SolidMolecular weight:419.83Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formula:C36H35ClN4O4Purity:99.63%Color and Shape:SolidMolecular weight:623.14TNIK-IN-3
CAS:<p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>Formula:C23H18FN3O2Purity:98.39%Color and Shape:SolidMolecular weight:387.41LDCA
CAS:<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Formula:C8H5Cl3FNOPurity:98.99%Color and Shape:SolidMolecular weight:256.49Ro24-7429
CAS:<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Formula:C14H13ClN4Purity:99.29% - 99.85%Color and Shape:SolidMolecular weight:272.73CCT020312
CAS:<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Formula:C31H30Br2N4O2Purity:98.63%Color and Shape:SolidMolecular weight:650.4Lanperisone HCl
CAS:<p>Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.</p>Formula:C15H19ClF3NOPurity:98.67% - >99.99%Color and Shape:SolidMolecular weight:321.77SPD304 dihydrochloride
CAS:<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Formula:C32H34Cl2F3N3O2Purity:99.25%Color and Shape:SolidMolecular weight:620.53JY-2
CAS:<p>JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.</p>Formula:C13H7Cl2N3OPurity:99.66%Color and Shape:SolidMolecular weight:292.12HBDDE
CAS:<p>HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.</p>Formula:C16H18O8Purity:97.94%Color and Shape:SolidMolecular weight:338.31A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formula:C29H37Cl3N6OPurity:99.75% - 99.96%Color and Shape:SolidMolecular weight:592GSK-3β inhibitor 3
CAS:<p>GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3</p>Formula:C18H14FNO2SPurity:97.53%Color and Shape:SolidMolecular weight:327.37NLRP3/AIM2-IN-3
CAS:<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Formula:C16H14N2O2Purity:97.04%Color and Shape:SolidMolecular weight:266.29ZDLD20
CAS:<p>ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.</p>Formula:C22H22N6OPurity:98.59%Color and Shape:SolidMolecular weight:386.45cRIPGBM chloride
CAS:<p>cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.</p>Formula:C26H20ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:446.9CDK9-IN-7
CAS:<p>CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.</p>Formula:C29H37N7O2SPurity:98.08%Color and Shape:SolidMolecular weight:547.71XX-650-23
CAS:<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Formula:C18H12N2O2Purity:97.01%Color and Shape:SolidMolecular weight:288.3DCG066
CAS:<p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>Formula:C30H31F6N3O2Purity:98.26% - 98.38%Color and Shape:SolidMolecular weight:579.58Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Formula:C42H50FN7O8S2Purity:99.05%Color and Shape:SolidMolecular weight:864.02Trk-IN-9
CAS:<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Formula:C23H24ClFN6OPurity:98.15%Color and Shape:SolidMolecular weight:454.93SB 699551 dihydrochloride
CAS:<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Formula:C34H47Cl2N3OPurity:99.83%Color and Shape:SolidMolecular weight:584.66C6 Ceramide
CAS:<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Formula:C24H47NO3Purity:99.67%Color and Shape:SolidMolecular weight:397.63RS1-PDK1 inhibitor
CAS:<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Formula:C15H9ClN2O2S3Purity:98.12%Color and Shape:SolidMolecular weight:380.89Brigimadlin
CAS:<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Formula:C31H25Cl2FN4O3Purity:98.17%Color and Shape:SolidMolecular weight:591.46Droloxifene
CAS:<p>Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.</p>Formula:C26H29NO2Purity:99.86% - 99.97%Color and Shape:Solid PowderMolecular weight:387.51R306465
CAS:<p>R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.</p>Formula:C19H19N5O4SPurity:98.46% - 99.54%Color and Shape:SolidMolecular weight:413.45H2L5186303
CAS:<p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>Formula:C26H20N2O8Purity:98.19%Color and Shape:SolidMolecular weight:488.45MBM-55
CAS:<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Formula:C28H27FN6O2Purity:99.83%Color and Shape:SolidMolecular weight:498.55SCFSkp2-IN-2
CAS:<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Formula:C17H20N4O2Purity:99.86%Color and Shape:SolidMolecular weight:312.37UCB-5307
CAS:<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formula:C22H21N3OPurity:98.76%Color and Shape:SolidMolecular weight:343.42OR-1896
CAS:<p>OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.</p>Formula:C13H15N3O2Purity:99.33%Color and Shape:SolidMolecular weight:245.28
