Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5599 products of "Apoptosis"
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KR-33493
CAS:<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Formula:C20H18BrN3O3SPurity:99.96%Color and Shape:SolidMolecular weight:460.34GSK854
CAS:<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Formula:C18H19ClN6O4S2Purity:98.79%Color and Shape:SolidMolecular weight:482.96CDK9-IN-7
CAS:<p>CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.</p>Formula:C29H37N7O2SPurity:98.08%Color and Shape:SolidMolecular weight:547.71Prinomastat
CAS:<p>Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.</p>Formula:C18H21N3O5S2Purity:99.23%Color and Shape:SolidMolecular weight:423.51DB1976
CAS:<p>DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.</p>Formula:C20H16N8SePurity:98.74%Color and Shape:SolidMolecular weight:447.35RIPK3-IN-1
CAS:<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Formula:C29H25FN4O4Purity:98.27%Color and Shape:SolidMolecular weight:512.53NM-3
CAS:<p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>Formula:C13H12O6Purity:99.89%Color and Shape:SolidMolecular weight:264.23Tubulin inhibitor 11
CAS:<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Formula:C22H23N3O3SPurity:98.32%Color and Shape:SoildMolecular weight:409.5AOH1160
CAS:<p>AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).</p>Formula:C25H20N2O3Purity:98.46% - 99.52%Color and Shape:SolidMolecular weight:396.44D609
CAS:<p>D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.</p>Formula:C11H15KOS2Purity:97.67% - 99.56%Color and Shape:Off-White PowderMolecular weight:266.46SCFSkp2-IN-2
CAS:<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Formula:C17H20N4O2Purity:99.86%Color and Shape:SolidMolecular weight:312.37Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formula:C36H35ClN4O4Purity:99.63%Color and Shape:SolidMolecular weight:623.14ZDLD20
CAS:<p>ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.</p>Formula:C22H22N6OPurity:98.59%Color and Shape:SolidMolecular weight:386.45TC-DAPK 6
CAS:<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Formula:C17H12N2O2Purity:98.73%Color and Shape:SolidMolecular weight:276.29BC 11 hydrobromide
CAS:<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Formula:C8H12BBrN2O2SPurity:98.07%Color and Shape:SolidMolecular weight:290.97Cipepofol
CAS:<p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>Formula:C14H20OPurity:99.77%Color and Shape:SolidMolecular weight:204.31Perphenazine dihydrochloride
CAS:<p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>Formula:C21H28Cl3N3OSPurity:99.67%Color and Shape:SolidMolecular weight:476.89A09-003
CAS:<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Formula:C23H26N4OPurity:99.61%Color and Shape:SolidMolecular weight:374.48HBDDE
CAS:<p>HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.</p>Formula:C16H18O8Purity:97.94%Color and Shape:SolidMolecular weight:338.31GSK-3β inhibitor 3
CAS:<p>GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3</p>Formula:C18H14FNO2SPurity:97.53%Color and Shape:SolidMolecular weight:327.37R306465
CAS:<p>R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.</p>Formula:C19H19N5O4SPurity:98.46% - 99.54%Color and Shape:SolidMolecular weight:413.45Ro 08-2750
CAS:<p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>Formula:C13H10N4O3Purity:98.795%Color and Shape:SolidMolecular weight:270.24Pyrazoloacridine
CAS:<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Formula:C19H21N5O3Purity:99.72%Color and Shape:SolidMolecular weight:367.4CP 461
CAS:<p>CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.</p>Formula:C25H22ClFN2OPurity:99.82%Color and Shape:SolidMolecular weight:420.91EGFR-IN-11
CAS:<p>EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.</p>Formula:C29H35N9O2SPurity:99.93%Color and Shape:SolidMolecular weight:573.71CCT018159
CAS:<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Formula:C20H20N2O4Purity:98.78% - 99.79%Color and Shape:SolidMolecular weight:352.38NecroX-7
CAS:<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Formula:C24H29N3O3SPurity:98.22%Color and Shape:SolidMolecular weight:439.57Mitazalimab
CAS:<p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>Purity:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidSTAT3-IN-13
CAS:<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formula:C21H20N6O3SPurity:98.89%Color and Shape:SolidMolecular weight:436.49GCN2-IN-1
CAS:<p>GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.</p>Formula:C19H18N10OPurity:99.49% - 99.64%Color and Shape:SolidMolecular weight:402.41K-8012
CAS:<p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>Formula:C23H23FN4Purity:99.72%Color and Shape:SolidMolecular weight:374.45MMRi64
CAS:<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Formula:C22H17Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:410.3DC_AC50
CAS:<p>"DC_AC50 inhibits Atox1/CCS to reduce cancer cell growth and prevent chemotherapy resistance."</p>Formula:C17H12BrF2N3OSPurity:99.84% - 99.9%Color and Shape:SolidMolecular weight:424.26WYE-132
CAS:<p>WYE-125132: potent mTOR inhibitor, IC50 0.19 nM, selective over PI3Ks/hSMG1/ATR.</p>Formula:C27H33N7O4Purity:99.16%Color and Shape:SolidMolecular weight:519.6Anticancer agent 81
CAS:<p>Compound 37b3, an anticancer, halts tumor growth, triggers cell death, and pairs with Trastuzumab to form T-PBA, an ADC with targeted delivery.</p>Formula:C46H46N6O5Purity:98%Color and Shape:SolidMolecular weight:762.89hGGPPS-IN-3
CAS:<p>13h (hGGPPS-IN-3), a strong C2-ThP-BPs hGGPPS blocker, triggers MM cell apoptosis and shows in vivo anti-myeloma effects.</p>Formula:C21H19BrN4O7P2SPurity:98%Color and Shape:SolidMolecular weight:613.31Antitumor agent-92
CAS:<p>Antitumor Agent-92, a derivative of Icaritin, halts cell cycle, triggers cell death, and is promising for liver cancer study.</p>Formula:C33H41NO10Purity:98%Color and Shape:SolidMolecular weight:611.68DX3-235
CAS:<p>DX3-235 is an oxidative phosphorylation (OXPHOS) inhibitor on mitochondrial complex I function in galactose-containing media, resulting in reduced ATP.</p>Formula:C26H39N5O6S2Purity:99.97%Color and Shape:SolidMolecular weight:581.75Antitumor agent-110
CAS:<p>Antitumor Agent-110 (Compound 13), an imidazotetrazine anticancer agent, exhibits excellent permeability.</p>Formula:C10H6N6OSPurity:98%Color and Shape:SolidMolecular weight:258.26Ethylene dimethanesulfonate
CAS:<p>Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diester</p>Formula:C4H10O6S2Purity:98.94%Color and Shape:SolidMolecular weight:218.25AM-8735
CAS:<p>AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).</p>Formula:C27H31Cl2NO6SPurity:98%Color and Shape:SolidMolecular weight:568.51Ro 41-5253
CAS:<p>Ro 41-5253 is a RARα antagonist with antitumor activity that inhibits the proliferation of ZR-75.1 estrogen receptor-positive breast cancer cells.</p>Formula:C28H36O5SPurity:98%Color and Shape:SolidMolecular weight:484.65NSC 689534
CAS:<p>NSC 689534 forms a chelate with copper (Cu 2+), resulting in the NSC 689534/Cu 2+ complex, which is a potent inducer of oxidative stress and exhibits antitumor activity [1].</p>Formula:C19H18N6SColor and Shape:SolidMolecular weight:362.45TC ASK 10
CAS:<p>TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1,IC50 = 14 nM). The IC50 value for ASK2 is 0.51 μM.</p>Formula:C21H23Cl2N5OPurity:99.86%Color and Shape:SolidMolecular weight:432.35JMJD3/HDAC-IN-1
CAS:<p>Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histone</p>Formula:C21H30N6O2Purity:98%Color and Shape:SolidMolecular weight:398.5IK-862
CAS:<p>IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.</p>Formula:C25H27N3O4Purity:97.75% - 98.29%Color and Shape:SolidMolecular weight:433.54E2RCat
CAS:<p>4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expression</p>Formula:C22H14ClNO4S2Purity:98.44%Color and Shape:SolidMolecular weight:455.93MTI-31
CAS:<p>MTI-31 (LXI-15029) is a potent oral mTORC1/2 inhibitor with a Kd of 0.20 nM, >5,000-fold selectivity, and an IC50 of 39 nM.</p>Formula:C26H30N6O3Purity:99.97%Color and Shape:SolidMolecular weight:474.55FLT3-IN-14
CAS:<p>FLT3-IN-14: FLT3 inhibitor; FLT3-WT IC50=5.6nM, FLT3-ITD IC50=1.4nM; blocks Y591 phosphorylation; G1 arrest; pro-apoptotic.</p>Formula:C25H24N6O2SColor and Shape:SolidMolecular weight:472.56IM156
CAS:<p>IM156, a Metformin derivative, activates AMPK, enhances cognition in aging animals, and inhibits OXPHOS in solid tumor research.</p>Formula:C13H16F3N5OPurity:99.67%Color and Shape:SolidMolecular weight:315.29
