CymitQuimica logo
Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.

Subcategories of "Cell Cycle/Checkpoint"

Show 10 more subcategories

Found 3888 products of "Cell Cycle/Checkpoint"

Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.
  • T-2513 hydrochloride

    CAS:
    T-2513 hydrochloride: selective topoisomerase I inhibitor, binds DNA complex, halts DNA/RNA synthesis, causes cell death.
    Formula:C25H28ClN3O5
    Color and Shape:Solid
    Molecular weight:485.96

    Ref: TM-T63225

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • GR 83895

    CAS:
    GR 83895 is an antagonist of prototype fibrinogen receptor.
    Formula:C29H39N9O8S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:673.74

    Ref: TM-T25460

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Antiviral agent 67

    CAS:
    Antiviralagent 67 (compound PC6) is an inhibitor of DENVNS5 (RNA-dependent RNA polymerase) with a Ki value of 1.12 nM.
    Formula:C19H19N3O
    Color and Shape:Solid
    Molecular weight:305.374

    Ref: TM-T206310

    10mg
    To inquire
    50mg
    To inquire
  • 3′-Amino-2′,3′-dideoxy-CTP

    CAS:
    3′-Amino-2′,3′-dideoxy-CTP is an analog of nucleoside triphosphates. It selectively inhibits DNA polymerase β.
    Formula:C9H17N4O12P3
    Color and Shape:Solid
    Molecular weight:466.17

    Ref: TM-TSW-01126

    10mg
    To inquire
    50mg
    To inquire
  • CHK1 inhibitor

    CAS:
    CHK1 inhibitor (GDC-0575 analog) is a CHK1 inhibitor.
    Formula:C17H21BrN4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:377.28

    Ref: TM-T10793

    25mg
    1,504.00€
    50mg
    1,963.00€
    100mg
    2,520.00€
  • 3-deoxy-3-fluoro-β-D-Ribofuranose 25

    CAS:
    Compound 25, β-D-Ribofuranose, 3-deoxy-3-fluoro-, 1,2-diacetate 5-(4-methylbenzoate), exhibits strong activity in inhibiting the growth of tumor cells [1].
    Formula:C17H19FO7
    Color and Shape:Solid
    Molecular weight:354.33

    Ref: TM-T87696

    10mg
    To inquire
    50mg
    To inquire
  • BWC0977

    CAS:
    BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.
    Formula:C22H21FN6O5
    Color and Shape:Solid
    Molecular weight:468.44

    Ref: TM-T201074

    25mg
    6,922.00€
    50mg
    9,712.00€
    100mg
    13,590.00€
  • Dyrk1A-IN-2


    Dyrk1A-IN-2 is a DYRK1A inhibitor (EC50: 37 nM). dyrk1A-IN-2 exhibits efficient promotion of human β-cell replication, as well as low cytotoxicity.
    Formula:C27H32N6O4
    Color and Shape:Solid
    Molecular weight:504.58

    Ref: TM-T63440

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • KL-50

    CAS:
    KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.
    Formula:C7H7FN6O2
    Color and Shape:Solid
    Molecular weight:226.17

    Ref: TM-T200136

    25mg
    1,690.00€
    50mg
    2,210.00€
    100mg
    2,879.00€
  • Cdc7-IN-10

    CAS:
    Cdc7-IN-10 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in studies of proliferative diseases.
    Formula:C20H22F2N4O2S
    Color and Shape:Solid
    Molecular weight:420.48

    Ref: TM-T62230

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • CBP/p300-IN-2

    CAS:
    CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc).
    Formula:C27H29F2N7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:521.56

    Ref: TM-T10702

    25mg
    2,300.00€
    50mg
    3,022.00€
    100mg
    4,085.00€
  • USP7-IN-6

    CAS:
    USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).
    Formula:C41H43N7O4S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:729.89

    Ref: TM-T13271

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Glycyl H-1152 hydrochloride

    CAS:
    Glycyl-H-1152 is a potent ROCK-II inhibitor (IC50=11.8 nM) with high selectivity over CaMKII, PKG, Aurora A, PKA, and PKC. Better than Y-27632 and HA-1077.
    Formula:C18H26Cl2N4O3S
    Color and Shape:Solid
    Molecular weight:449.39

    Ref: TM-T35459

    1mg
    575.00€
    5mg
    2,367.00€
    10mg
    4,123.00€
    500µg
    304.00€
  • Haspin-IN-2

    CAS:
    Haspin-IN-2 is a potent haspin inhibitor (IC50: 50 nM) and also inhibits CLK1 (IC50: 445 nM) and DYRK1A (IC50: 917 nM).
    Formula:C12H8N4O3
    Color and Shape:Solid
    Molecular weight:256.22

    Ref: TM-T60394

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CDK8-IN-9


    CDK8-IN-9, potent CDK8 inhibitor (IC50: 48.6 nM), curbs tumor growth, useful for colorectal cancer research.
    Color and Shape:Solid

    Ref: TM-T64245

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Aurora/LIM kinase-IN-1


    Aurora/LIM kinase-IN-1 (Compound F114) is a dual inhibitor targeting aurora and lim kinases, potentially useful in GBM cancer treatment efforts.
    Formula:C16H20N6O
    Color and Shape:Solid
    Molecular weight:312.37

    Ref: TM-T60783

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Cdc7-IN-8

    CAS:
    Cdc7-IN-8, inhibits Cdc7 kinase, key in DNA replication, and is promising for cancer research. (WO2021032170A1)
    Formula:C19H21N5O2
    Color and Shape:Solid
    Molecular weight:351.40

    Ref: TM-T61224

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • LNA-AMP

    CAS:
    LNA-AMP is a nucleotide analog used in the synthesis of oligonucleotides.
    Formula:C11H14N5O7P
    Color and Shape:Solid
    Molecular weight:359.23

    Ref: TM-TSW-00964

    10mg
    To inquire
    50mg
    To inquire
  • CHK-IN-1

    CAS:
    CHK-IN-1 is a dual inhibitor of CHK1 and CHK2 with antiproliferative activity.
    Formula:C18H19ClFN5OS
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:407.89

    Ref: TM-T13148

    1mg
    630.00€
    5mg
    1,603.00€
  • L-I-OddU

    CAS:
    L-I-OddU: Selective anti-EBV, halts virus DNA/protein synthesis. EC50: 0.03 µM, low toxicity (CC50: 1000 nM).
    Formula:C8H9IN2O5
    Color and Shape:Solid
    Molecular weight:340.07

    Ref: TM-T61080

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • 2′-O-MOE-AMP

    CAS:
    2′-O-MOE-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.
    Formula:C13H20N5O8P
    Color and Shape:Solid
    Molecular weight:405.30

    Ref: TM-TSW-00946

    10mg
    To inquire
    50mg
    To inquire
  • CDK7-IN-17

    CAS:
    CDK7-IN-17 (compound 11) is a pyrimidine-derived CDK7 inhibitor for studying transcription-disrupted cancers.
    Formula:C24H26F3N6OP
    Purity:99.60%
    Color and Shape:Solid
    Molecular weight:502.47

    Ref: TM-T63410

    1mg
    264.00€
    5mg
    650.00€
    10mg
    888.00€
    25mg
    1,369.00€
    50mg
    1,783.00€
  • CDK7/12-IN-1

    CAS:
    CDK7/12-IN-1 is a selective CDK7 (IC50: 3 nM) and CDK12 (IC50: 277 nM) inhibitor, effective against tumor growth.
    Formula:C25H34N8O
    Color and Shape:Solid
    Molecular weight:462.59

    Ref: TM-T62926

    25mg
    1,639.00€
  • Kolavenic acid analog

    CAS:
    KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.
    Formula:C25H38O4
    Color and Shape:Solid
    Molecular weight:402.57

    Ref: TM-T61970

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • DS96432529


    DS96432529 is a potent and orally active bone anabolic agent through CDK8 inhibition.
    Formula:C18H26N4O3S
    Color and Shape:Soild
    Molecular weight:378.49

    Ref: TM-T61590

    25mg
    1,341.00€
    50mg
    1,746.00€
    100mg
    2,835.00€
  • CDK2-IN-31

    CAS:
    CDK2-IN-31 (compound I-125A) is an inhibitor of CDK2 and is utilized in cancer research.
    Formula:C37H52N6O5
    Color and Shape:Solid
    Molecular weight:660.85

    Ref: TM-T201156

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • MRL-436

    CAS:
    MRL-436 is an RNA polymerase inhibitor with antibacterial activity. Its effectiveness depends on the β' subunit and the 622nd residue of the RNAP ω subunit. MRL-436 can inhibit Rifampicin-resistant RNA polymerase derivatives and shows antibacterial activity against Rifampicin-resistant strains.
    Formula:C24H22N4O
    Color and Shape:Solid
    Molecular weight:382.46

    Ref: TM-T212262

    10mg
    To inquire
    50mg
    To inquire
  • D-G23

    CAS:
    D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.
    Formula:C19H22N4O3
    Color and Shape:Solid
    Molecular weight:354.403

    Ref: TM-T206763

    10mg
    To inquire
    50mg
    To inquire
  • Antibacterial agent 110


    Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).
    Formula:C22H21N5O4S
    Color and Shape:Solid
    Molecular weight:451.5

    Ref: TM-T62740

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • LIMK1 inhibitor 2

    CAS:
    LIMK1 inhibitor 2 (compound 41) is a LIMK1 inhibitor with an IC50 value of 9 μM.
    Formula:C10H11N3OS
    Color and Shape:Solid
    Molecular weight:221.279

    Ref: TM-T204765

    10mg
    To inquire
    50mg
    To inquire
  • Dencatistat

    CAS:
    Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.
    Formula:C24H27N7O5S
    Purity:98.85%
    Color and Shape:Solid
    Molecular weight:525.58

    Ref: TM-T86106

    1mg
    86.00€
    5mg
    180.00€
    10mg
    279.00€
    25mg
    558.00€
    50mg
    912.00€
    100mg
    1,454.00€
    200mg
    1,882.00€
  • Cdc7-IN-11

    CAS:
    Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.
    Formula:C20H22F2N4O2S
    Color and Shape:Solid
    Molecular weight:420.48

    Ref: TM-T62231

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • WEE1-IN-11

    CAS:
    WEE1-IN-11 (Compound 13) serves as a potent CDK2 inhibitor with an IC50 of 2.0 nM. It exhibits inhibitory effects on several cell lines, including NCI-H446, A427, OVCAR3, C33A, and WiDr, with respective IC50 values of 93.9, 34.5, 86.7, 23.1, and 85 nM.
    Formula:C26H29FN8OS2
    Color and Shape:Solid
    Molecular weight:552.69

    Ref: TM-T200924

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • BAY-364

    CAS:
    BAY-364 (BAY-299N) functions as an inhibitor targeting the second bromine domain in TAF1, demonstrating inhibitory effects on TAF1 in Kasumi-1 cells, CD34+
    Formula:C23H19N3O4
    Color and Shape:Solid
    Molecular weight:401.41

    Ref: TM-T73451

    25mg
    1,639.00€
    50mg
    2,142.00€
    100mg
    2,790.00€
  • AJI-214

    CAS:
    AJI-214 functions as a dual-target inhibitor that specifically blocks Aurora kinase A and JAK2. By directly inhibiting Aurora kinase A, AJI-214 prevents mitotic progression and cell polarity in T cells while concurrently suppressing JAK2 activation to reduce STAT3 phosphorylation. This inhibition decreases the differentiation of TH1 and TH17 cells. AJI-214 is utilized in research focused on the modulation of immune responses and the prevention of graft-versus-host disease (GVHD).
    Formula:C17H13ClFN5O
    Color and Shape:Solid
    Molecular weight:357.77

    Ref: TM-T200387

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • DYR530

    CAS:
    DYR530 is a ligand for the target protein (protein kinase DYRK1A) of PROTAC.
    Formula:C23H24FN7
    Color and Shape:Solid
    Molecular weight:417.48

    Ref: TM-T201243

    25mg
    1,554.00€
    50mg
    2,025.00€
    100mg
    2,508.00€
  • MtTMPK-IN-2

    CAS:
    MtTMPK-IN-2 inhibits M. tuberculosis TMPK (IC50: 1.1 μM), Mtb H37Rv (MIC: 12.5 μM), and is cytotoxic in MRC-5 cells (EC50: 6.1 μM).
    Formula:C23H24ClN3O3
    Color and Shape:Solid
    Molecular weight:425.91

    Ref: TM-T62305

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • AJI-100

    CAS:
    AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective IC50 values of 12.7 nM and 18.5 nM. It inhibits T cell mitosis and cell polarity by directly targeting Aurora kinase A and reduces STAT3 phosphorylation by inhibiting JAK2 activation, consequently diminishing the differentiation of TH1 and TH17 cells. This compound is utilized in researching immune response regulation and the prevention of graft-versus-host disease (GVHD).
    Formula:C17H14FN5O
    Color and Shape:Solid
    Molecular weight:323.32

    Ref: TM-T200052

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Lisavanbulin

    CAS:
    Lisavanbulin (BAL-101553) is a prodrug of Avanbulin (BAL 27862), a microtubule-targeting agent. It exhibits antitumor activity, particularly effective against tumors with high expression of end-binding protein 1.
    Formula:C26H29N9O3
    Color and Shape:Solid
    Molecular weight:515.57

    Ref: TM-T88188

    10mg
    To inquire
    50mg
    To inquire
  • Methyl 3-oxodecanoate

    CAS:
    Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.
    Formula:C11H20O3
    Color and Shape:Solid
    Molecular weight:200.275

    Ref: TM-T206384

    10mg
    To inquire
    50mg
    To inquire
  • MtTMPK-IN-1


    MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.
    Formula:C22H24N4O3
    Color and Shape:Solid
    Molecular weight:392.45

    Ref: TM-T61796

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CLK1/4-IN-1


    CLK1/4-IN-1 inhibits Clk1/4 (IC50: 9.7/6.6 nM), curbing T24 cell growth (GI50: 1.1 μM). Potential cancer research tool.
    Formula:C18H14ClNO4S
    Color and Shape:Solid
    Molecular weight:375.83

    Ref: TM-T61543

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • Antitumor agent-74


    Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.
    Formula:C26H23FN6
    Color and Shape:Solid
    Molecular weight:438.5

    Ref: TM-T62509

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CYP2C19-IN-1


    CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.
    Formula:C26H26N2O6S
    Color and Shape:Solid
    Molecular weight:494.56

    Ref: TM-T63337

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • Tetrahydrouridine dihydrate


    THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.
    Formula:C9H20N2O8
    Color and Shape:Solid
    Molecular weight:284.26

    Ref: TM-T60553

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • 3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite

    CAS:
    3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.
    Formula:C41H50N9O3P
    Color and Shape:Solid
    Molecular weight:747.87

    Ref: TM-TSW-01106

    10mg
    To inquire
    50mg
    To inquire
  • CDK9-IN-13


    CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.
    Formula:C27H35N5O2
    Color and Shape:Solid
    Molecular weight:461.6

    Ref: TM-T62919

    25mg
    1,108.00€
    50mg
    1,449.00€
    100mg
    2,385.00€
  • DYRKs-IN-1 hydrochloride

    CAS:
    DYRKs-IN-1 HCl inhibits DYRK1A (5 nM IC50) & DYRK1B (8 nM IC50) with antitumor properties.
    Formula:C30H31Cl2N7O4
    Color and Shape:Solid
    Molecular weight:624.52

    Ref: TM-T72242

    25mg
    2,205.00€
    50mg
    2,872.00€
    100mg
    4,680.00€
  • 4,5'-Dimethylangelicin-NHS


    NHS-modified coumarin, 4,5'-Dimethylangelicin-NHS, shows photochemical activity & photosensitivity.
    Formula:C21H19NO7S
    Color and Shape:Solid
    Molecular weight:429.44

    Ref: TM-T62365

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • AB25583

    CAS:
    AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.
    Formula:C22H17ClN4O3S
    Color and Shape:Solid
    Molecular weight:452.91

    Ref: TM-T200101

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • MtTMPK-IN-9


    MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.
    Formula:C25H26N6O7
    Color and Shape:Solid
    Molecular weight:522.51

    Ref: TM-T63657

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • LNA-CTP

    CAS:

    LNA-CTP is a nucleotide analog utilized in the synthesis of oligonucleotides.

    Formula:C10H16N3O14P3
    Color and Shape:Solid
    Molecular weight:495.17

    Ref: TM-TSW-00954

    10mg
    To inquire
    50mg
    To inquire
  • Aurora B inhibitor 1

    CAS:
    Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.
    Formula:C25H26ClF2N7O2
    Purity:98.37%
    Color and Shape:Solid
    Molecular weight:529.97

    Ref: TM-T12010

    1mg
    630.00€
    5mg
    1,620.00€
  • 2′-OMe-UMP

    CAS:
    2′-OMe-UMP is a nucleotide analog used in the synthesis of oligonucleotides.
    Formula:C10H15N2O9P
    Molecular weight:338.21

    Ref: TM-TSW-00966

    10mg
    To inquire
    50mg
    To inquire
  • WRN inhibitor 11

    CAS:
    WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.
    Formula:C34H35ClF3N9O5
    Color and Shape:Solid
    Molecular weight:742.15

    Ref: TM-T201262

    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • UM-C162

    CAS:
    UM-C162, a benzimidazole derivative, offers protection to nematodes from Staphylococcus aureus infections. It inhibits biofilm formation without impairing bacterial viability. Additionally, UM-C162 disrupts the production of Staphylococcus aureus hemolysins, proteases, and coagulases. This compound holds potential as an antivirulence agent for managing Staphylococcus aureus infections.
    Formula:C30H25N3O4
    Color and Shape:Solid
    Molecular weight:491.54

    Ref: TM-T201580

    10mg
    To inquire
    50mg
    To inquire
  • Antiangiogenic agent 2


    Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.

    Formula:C26H26FN3O4
    Color and Shape:Solid
    Molecular weight:463.5

    Ref: TM-T62931

    25mg
    1,444.00€
    50mg
    1,882.00€
    100mg
    2,375.00€
  • MtTMPK-IN-8


    MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.
    Formula:C24H24N6O7
    Color and Shape:Solid
    Molecular weight:508.48

    Ref: TM-T63491

    25mg
    1,369.00€
    50mg
    1,783.00€
    100mg
    2,250.00€
  • CDK4/6-IN-3

    CAS:
    CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.
    Formula:C25H31FN8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.57

    Ref: TM-T10737

    25mg
    3,619.00€
    50mg
    4,573.00€
    100mg
    6,120.00€
  • Elacytarabine

    CAS:
    Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.
    Formula:C27H45N3O6
    Purity:97.69%
    Color and Shape:Solid
    Molecular weight:507.66

    Ref: TM-T15009

    25mg
    63.00€
    50mg
    To inquire
    1mL*10mM (DMSO)
    34.00€
  • Zelasudil

    CAS:
    Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.
    Formula:C22H21F2N7O
    Purity:99.15%
    Color and Shape:Solid
    Molecular weight:437.445

    Ref: TM-T69665

    1mg
    92.00€
    5mg
    168.00€
    10mg
    248.00€
    25mg
    421.00€
    50mg
    587.00€
    100mg
    820.00€
    1mL*10mM (DMSO)
    170.00€
  • USP15-IN-1

    CAS:
    USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM).
    Formula:C22H23N3O3
    Purity:99.509% - 99.81%
    Color and Shape:Solid
    Molecular weight:377.44

    Ref: TM-T61575

    1mg
    119.00€
    5mg
    289.00€
    10mg
    460.00€
    25mg
    747.00€
    50mg
    1,035.00€
    100mg
    1,395.00€
    500mg
    2,673.00€
  • GFB-12811

    CAS:
    GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.
    Formula:C22H23F4N5O
    Purity:98.88%
    Color and Shape:Solid
    Molecular weight:449.44

    Ref: TM-T62695

    1mg
    281.00€
    5mg
    708.00€
    10mg
    1,108.00€
    25mg
    2,097.00€
    50mg
    3,052.00€
    1mL*10mM (DMSO)
    700.00€
  • HRO761

    CAS:
    HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.
    Formula:C31H31ClF3N9O5
    Purity:98.74% - 99.62%
    Color and Shape:Solid
    Molecular weight:702.08

    Ref: TM-T72107

    1mg
    57.00€
    5mg
    118.00€
    10mg
    167.00€
    25mg
    280.00€
    50mg
    475.00€
    100mg
    708.00€
    1mL*10mM (DMSO)
    778.00€
  • CTPS1-IN-1

    CAS:
    CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.
    Formula:C21H22N6O4S2
    Purity:99.46%
    Color and Shape:Solid
    Molecular weight:486.57

    Ref: TM-T86105

    1mg
    163.00€
    5mg
    394.00€
    10mg
    620.00€
    25mg
    964.00€
    50mg
    1,288.00€
    100mg
    1,738.00€
    200mg
    2,367.00€
  • VCPIP1-IN-1

    CAS:
    VCPIP1-IN-1 is a VCPIP1 inhibitor used in cancer research.
    Formula:C13H15ClN2O2
    Purity:99.3%
    Color and Shape:Solid
    Molecular weight:266.72

    Ref: TM-T88664

    1mg
    47.00€
    5mg
    92.00€
    10mg
    145.00€
    25mg
    281.00€
    50mg
    447.00€
    100mg
    715.00€
    200mg
    964.00€
    1mL*10mM (DMSO)
    101.00€
  • LY3143921 hydrate

    CAS:
    LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].
    Formula:C16H14FN5O2
    Purity:98.43%
    Color and Shape:Solid
    Molecular weight:327.31

    Ref: TM-T9064

    1mg
    50.00€
    5mg
    92.00€
    10mg
    133.00€
    25mg
    216.00€
    50mg
    329.00€
    100mg
    504.00€
  • SR 11302

    CAS:
    SR 11302 is an inhibitor of activator protein-1 (AP-1).
    Formula:C26H32O2
    Purity:98.65%
    Color and Shape:Solid
    Molecular weight:376.53

    Ref: TM-T23384

    1mg
    93.00€
    5mg
    137.00€
    10mg
    205.00€
    25mg
    356.00€
    50mg
    587.00€
    100mg
    888.00€
    1mL*10mM (DMSO)
    150.00€
  • INCB086550

    CAS:
    INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.
    Formula:C41H39N7O4
    Purity:98.49%
    Color and Shape:Solid
    Molecular weight:693.79

    Ref: TM-T36899

    1mg
    145.00€
    5mg
    359.00€
    10mg
    540.00€
    25mg
    868.00€
    50mg
    1,169.00€
    100mg
    1,596.00€
  • Bicyclomycin benzoate

    CAS:
    Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.
    Formula:C19H22N2O8
    Color and Shape:Solid
    Molecular weight:406.39

    Ref: TM-T10541

    1mg
    Discontinued
    Discontinued product
  • Troxacitabine

    CAS:
    Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.
    Formula:C8H11N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:213.19

    Ref: TM-T17175

    1mg
    Discontinued
    Discontinued product
  • 5'-O-DMT-N6-ibu-dA

    CAS:
    5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.
    Formula:C35H37N5O6
    Color and Shape:Solid
    Molecular weight:623.71

    Ref: TM-T39332

    ne
    Discontinued
    Discontinued product
  • Ethynylcytidine

    CAS:
    Ethynylcytidine is a nucleoside antimetabolite.
    Formula:C11H13N3O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:267.24

    Ref: TM-TQ0006

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product
  • Tanuxiciclib

    CAS:
    Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor, specifically designed to interfere with cell cycle progression by inhibiting the activity of CDKs, which are crucial regulators of cell division.
    Formula:C15H13FN6O
    Color and Shape:Solid
    Molecular weight:312.308

    Ref: TM-T39404

    ne
    Discontinued
    Discontinued product
  • Formycin A

    CAS:
    Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.
    Formula:C10H13N5O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:267.24

    Ref: TM-T11312

    5mg
    Discontinued
    Discontinued product
  • NSC639828

    CAS:
    NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.
    Formula:C18H13BrClN5O3
    Color and Shape:Solid
    Molecular weight:462.69

    Ref: TM-T38742

    ne
    Discontinued
    Discontinued product
  • GSK-3/CDK5/CDK2-IN-1

    CAS:
    GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].
    Formula:C21H22N4O2
    Color and Shape:Solid
    Molecular weight:362.433

    Ref: TM-T35555

    ne
    Discontinued
    Discontinued product
  • 3BrB-PP1

    CAS:
    3BrB-PP1 is an ATP-competitive analog that exhibits specific inhibitory activity towards protein kinase, particularly effective against protein kinases with mutations in the ATP-binding pocket, such as the Thr97 mutation within Sty1's ATP-binding pocket.
    Formula:C16H18BrN5
    Color and Shape:Solid
    Molecular weight:360.259

    Ref: TM-T41113

    ne
    Discontinued
    Discontinued product
  • 2'-Deoxy-2'-fluoro-5-iodouridine

    CAS:
    2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.
    Formula:C9H10FIN2O5
    Color and Shape:Solid
    Molecular weight:372.09

    Ref: TM-TNU0622

    ne
    Discontinued
    Discontinued product
  • PLK1-IN-6


    PLK1-IN-6: potent, selective PLK1 inhibitor, IC50 = 0.45 nM, hinders cancer cell growth.

    Formula:C28H37N9O3
    Color and Shape:Solid
    Molecular weight:547.65

    Ref: TM-T74777

    5mg
    Discontinued
    50mg
    Discontinued
    Discontinued product
  • 5'-DMT-3'-TBDMS-ibu-rG

    CAS:
    5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.
    Formula:C41H51N5O8Si
    Color and Shape:Solid
    Molecular weight:769.96

    Ref: TM-T40919

    ne
    Discontinued
    Discontinued product
  • N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine

    CAS:
    N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine, catalog number T66118 and CAS number 64325-78-6, is a valuable organic compound for life sciences research.
    Formula:C38H35N5O6
    Color and Shape:Solid
    Molecular weight:657.727

    Ref: TM-T66118

    ne
    Discontinued
    Discontinued product
  • MitoE10

    CAS:
    MitoE10 is an effective mitochondrial targeting antioxidant.
    Formula:C42H55O5PS
    Color and Shape:Solid
    Molecular weight:702.92

    Ref: TM-T33406

    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product
  • Ribocil-C

    CAS:
    Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.
    Formula:C21H21N7OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:419.5

    Ref: TM-T12722L

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product
  • 6-Amino-5-nitropyridin-2-one

    CAS:
    6-Amino-5-nitropyridin-2-one, a pyridine derivative, serves as a nucleobase within hachimoji DNA, where it is specifically paired with 5-aza-7-deazaguanine.
    Formula:C5H5N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:155.11

    Ref: TM-T19157

    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product
  • Tibremciclib

    CAS:

    Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].

    Formula:C28H32F2N8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:518.6

    Ref: TM-T79863

    ne
    Discontinued
    5mg
    Discontinued
    50mg
    Discontinued
    Discontinued product
  • PHI-101

    CAS:

    PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.

    Formula:C19H19FN4O2S
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:386.44

    Ref: TM-T81490

    1mg
    Discontinued
    5mg
    Discontinued
    10mg
    Discontinued
    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    200mg
    Discontinued
    Discontinued product
  • YK-2168

    CAS:

    YK-2168 is a differentiated selective inhibitor of CDK9.

    Formula:C16H18ClN5
    Color and Shape:Solid
    Molecular weight:315.80

    Ref: TM-T200769

    10mg
    Discontinued
    25mg
    Discontinued
    50mg
    Discontinued
    100mg
    Discontinued
    Discontinued product