Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(541 products)
- Cell Cycle Arrest(5 products)
- Chk(48 products)
- DYRK(48 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(180 products)
- Integrin(239 products)
- Kinesin(88 products)
- LIM Kinase(20 products)
- Microtubule Associated(275 products)
- PKC(117 products)
- PLK(25 products)
- ROCK(63 products)
- Rho(5 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3827 products of "Cell Cycle/Checkpoint"
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FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Formula:C17H18FN3SPurity:98.61%Color and Shape:SolidMolecular weight:315.41Dalpiciclib
CAS:Dalpiciclib (SHR-6390) selectively inhibits CDK4/6 (IC50: 12.4/9.9 nM), is orally available, and impedes esophageal cancer growth.
Formula:C25H30N6O2Purity:99.69%Color and Shape:SolidMolecular weight:446.54Sarecycline free base
CAS:Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.Formula:C24H29N3O8Purity:98%Color and Shape:SolidMolecular weight:487.5Pritelivir
CAS:Pritelivir (BAY 57-1293) (BAY 57-1293) is a potent helicase-primase inhibitor with active against HSV-1 and HSV-2 (IC50: 20 nM).Formula:C18H18N4O3S2Purity:97.96% - 99.42%Color and Shape:SolidMolecular weight:402.49CX-5461 dihydrochloride
CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).Formula:C27H29Cl2N7O2SColor and Shape:SolidMolecular weight:586.54Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFormula:C25H23FN4OPurity:98.38%Color and Shape:SolidMolecular weight:414.47Ref: TM-T8873
1mg49.00€5mg104.00€10mg166.00€25mg325.00€50mg490.00€100mg737.00€500mg1,483.00€1mL*10mM (DMSO)115.00€AT13148
CAS:AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.Formula:C17H16ClN3OPurity:98.04% - ≥95%Color and Shape:SolidMolecular weight:313.78Calcium N5-methyltetrahydrofolate
CAS:Calcium N5-methyltetrahydrofolate (NSC-173328) is the calcium salt of levomefolic acid, which has been proposed for treatment of cardiovascular disease andFormula:C20H23CaN7O6Purity:99.41%Color and Shape:SolidMolecular weight:497.51Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Formula:C17H14N4Purity:99.74%Color and Shape:SolidMolecular weight:274.32Ref: TM-T5673
1mg34.00€5mg73.00€10mg94.00€25mg177.00€50mg323.00€100mg460.00€200mg622.00€1mL*10mM (DMSO)71.00€AT7519 TFA
CAS:AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.Formula:C18H18Cl2F3N5O4Color and Shape:SolidMolecular weight:496.27Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:SolidMolecular weight:482.55Ref: TM-T4226
1mg34.00€5mg71.00€10mg92.00€25mg152.00€50mg222.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)52.00€GLPG0187
CAS:GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formula:C29H37N7O5SPurity:99.4% - 99.70%Color and Shape:SolidMolecular weight:595.71Ref: TM-T4259
1mg44.00€5mg98.00€10mg144.00€25mg236.00€50mg350.00€100mg522.00€500mg1,134.00€1mL*10mM (DMSO)129.00€SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFormula:C15H19Br2ClN4Purity:98.13% - 98.47%Color and Shape:SolidMolecular weight:450.6Antitumor agent-152
CAS:Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.
Formula:C17H19N5O2S2Purity:95.00%Color and Shape:SolidMolecular weight:389.5Roniciclib
CAS:Roniciclib (BAY 1000394) is a potent pan-CDK inhibitor and a novel oral cytotoxic agent. Roniciclib inhibits the activity of cell-cycle CDKs CDK1, CDK2, CDK3, CDK4, and of transcriptional CDKs CDK7 and CDK9 with IC(50) values in the range between 5 and 25 nmol/L.Formula:C18H21F3N4O3SPurity:98% - 98.63%Color and Shape:SolidMolecular weight:430.44Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Formula:C9H12N2O5SPurity:99.91%Color and Shape:SolidMolecular weight:260.27CC-671
CAS:CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.Formula:C28H28N6O4Purity:98.66% - 98.8%Color and Shape:SolidMolecular weight:512.56Ref: TM-T4482
1mg50.00€5mg105.00€10mg170.00€25mg340.00€50mg512.00€100mg733.00€500mg1,513.00€1mL*10mM (DMSO)120.00€Folinic acid calcium hydrate
CAS:Folinic acid (Leucovorin) calcium hydrate is a biofolic acid often used as a rescue agent with methotrexate (MTX) to reduce MTX-induced toxicity.Formula:C20H23CaN7O8Color and Shape:SolidMolecular weight:529.523Acelarin
CAS:Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Formula:C25H27F2N4O8PPurity:99.26%Color and Shape:SolidMolecular weight:580.47Danofloxacin
CAS:Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.Formula:C19H20FN3O3Purity:99.77% - 99.8%Color and Shape:SolidMolecular weight:357.38
