
Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(94 products)
- CDK(500 products)
- Cell Cycle Arrest(4 products)
- Chk(42 products)
- DYRK(48 products)
- Dynamin(23 products)
- Ferroptosis(215 products)
- HSP(169 products)
- Integrin(224 products)
- Kinesin(66 products)
- LIM Kinase(19 products)
- Microtubule Associated(262 products)
- PKC(102 products)
- PLK(28 products)
- ROCK(69 products)
- Rho(2 products)
- Wee1(15 products)
- c-Myc(69 products)
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Found 3482 products of "Cell Cycle/Checkpoint"
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5'-DMT-5-F-2'-dU Phosphoramidite
CAS:<p>5'-DMT-5-F-2'-dU Phosphoramidite is a nucleoside phosphoramidite analog employed in oligonucleotide synthesis. It plays a crucial role in developing therapeutic oligonucleotides, which are used in crafting drugs for cancer treatment.</p>Formula:C39H46FN4O8PColor and Shape:SolidMolecular weight:748.777CDK9 autophagic degrader 1
CAS:<p>CDK9 autophagic degrader 1 (Compound 28) is an ATTEC degrader used to target and degrade CDK9, also impacting the levels of its associated Cyclin T1. At a concentration of 100 nM, it exhibits over 80% inhibition of CDK9.</p>Formula:C34H39N7O4S2Color and Shape:SolidMolecular weight:673.8487-Methylguanosine 5′-monophosphate
CAS:<p>7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a component of nucleic acids.</p>Formula:C11H16N5O8PColor and Shape:SolidMolecular weight:377.25LNA-GDP
CAS:<p>LNA-GDP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>Formula:C11H15N5O11P2Color and Shape:SolidMolecular weight:455.21AB25583
CAS:<p>AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.</p>Formula:C22H17ClN4O3SColor and Shape:SolidMolecular weight:452.91CDK4/6-IN-3
CAS:<p>CDK4/6-IN-3 is a brain-penetrant CDK4/CDK6 inhibitor (Kis: <0.3 nM and 2.2 nM) used for the treatment of glioblastoma. It inhibits CDK1 with a Ki of 110 nM.</p>Formula:C25H31FN8Purity:98%Color and Shape:SolidMolecular weight:462.57MtTMPK-IN-8
<p>MtTMPK-IN-8 inhibits MtbTMPK, has low cytotoxicity, shows 0.78-9.4 μM activity against Mycobacterium, useful for tuberculosis research.</p>Formula:C24H24N6O7Color and Shape:SolidMolecular weight:508.4812(S)-HETE
CAS:<p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>Formula:C20H32O3Color and Shape:SolidMolecular weight:320.47LIMK1 inhibitor 2
CAS:<p>LIMK1 inhibitor 2 (compound 41) is a LIMK1 inhibitor with an IC50 value of 9 μM.</p>Formula:C10H11N3OSColor and Shape:SolidMolecular weight:221.279Metesind Glucuronate
CAS:<p>Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.</p>Formula:C29H34N4O10SColor and Shape:SolidMolecular weight:630.67Valopicitabine dihydrochloride
CAS:<p>Valopicitabine, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>Formula:C15H25ClN4O6Color and Shape:SolidMolecular weight:392.84Antibacterial agent 110
<p>Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).</p>Formula:C22H21N5O4SColor and Shape:SolidMolecular weight:451.5CDK4/9-IN-1
CAS:<p>CDK4/9-IN-1 (Compound 29) is a selective dual inhibitor of CDK4 and CDK9, exhibiting IC50 values of 23 nM and 12 nM, respectively. It holds potential for use in cancer research.</p>Formula:C22H34N6O2Color and Shape:SolidMolecular weight:414.544Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Formula:C26H26FN3O4Color and Shape:SolidMolecular weight:463.5P162-0948
CAS:<p>P162-0948 is a selective CDK8 inhibitor with an IC50 value of 50.4 nM. It reduces cell migration and the expression of EMT-related proteins in the A549 human alveolar epithelial cell line. Furthermore, P162-0948 decreases Smad phosphorylation, indicating disruption of the TGF-β/Smad signaling pathway, making it a promising compound for pulmonary fibrosis research.</p>Formula:C20H15FN4O2Color and Shape:SolidMolecular weight:362.3572'-O-MOE-UTP
CAS:<p>2'-O-MOE-UTP is a nucleotide analog employed in the synthesis of oligonucleotides.</p>Formula:C12H21N2O16P3Color and Shape:SolidMolecular weight:542.225-Methylcytosine hydrochloride
CAS:<p>5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.</p>Formula:C5H8ClN3OColor and Shape:SolidMolecular weight:161.59JY-3-094
CAS:<p>JY-3-094 is a selective Myc inhibitor that targets the hydrophobic domain of Myc and inhibits the formation of the Myc-Max heterodimer, with an IC50 of 33 μM, and can be used for cancer research.</p>Formula:C13H8N4O5Purity:98.72%Color and Shape:SolidMolecular weight:300.23CDK7-IN-17
CAS:<p>CDK7-IN-17, a pyrimidine-based CDK7 inhibitor, shows promise for various cancers, especially with abnormal transcription.</p>Formula:C24H26F3N6OPColor and Shape:SolidMolecular weight:502.47IIP0943
CAS:<p>IIP0943 is a selective PLK1 (polo-like kinase 1) inhibitor with an IC50 of 5.1 nM for PLK1. It also exhibits inhibitory activity on the proliferation of HCT116 cells, with an IC50 of 0.22 µM. IIP0943 shows potential for research in the field of oncology.</p>Formula:C26H28N6O3SColor and Shape:SolidMolecular weight:504.604

