Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(543 products)
- Cell Cycle Arrest(5 products)
- Chk(47 products)
- DYRK(48 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(228 products)
- Kinesin(88 products)
- LIM Kinase(20 products)
- Microtubule Associated(273 products)
- PKC(119 products)
- PLK(25 products)
- ROCK(63 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
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Found 3827 products of "Cell Cycle/Checkpoint"
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THZ2
CAS:THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).Formula:C31H28ClN7O2Purity:98.28%Color and Shape:SolidMolecular weight:566.05DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.Formula:C41H49N4O9PPurity:98.28%Color and Shape:SolidMolecular weight:772.82BMS-3
CAS:BMS-3 is a potent LIMK inhibitor with IC50s of 5 nM and 6 nM for LIMK1 and LIMK2, respectively.Formula:C17H12Cl2F2N4OSPurity:99.31% - 99.81%Color and Shape:SolidMolecular weight:429.27Palbociclib dihydrochloride
Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.Formula:C24H31Cl2N7O2Color and Shape:SolidMolecular weight:520.45Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formula:C20H18FNO4Purity:98.33% - 99.58%Color and Shape:SolidMolecular weight:355.36Tipiracil hydrochloride
CAS:Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Formula:C9H12Cl2N4O2Purity:98.13% - ≥95%Color and Shape:SolidMolecular weight:279.12BSJ-4-116
CAS:BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription termination.Formula:C40H49ClN8O8SPurity:99.09%Color and Shape:SolidMolecular weight:837.38SEL120-34A HCl
CAS:SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with IC50s of 4.4 nM and 10.4 nM , respectivelyFormula:C15H19Br2ClN4Purity:98.13% - 98.47%Color and Shape:SolidMolecular weight:450.6USP7/USP47 inhibitor
CAS:USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,Formula:C18H11Cl2N3O3S3Purity:98.5% - 98.71%Color and Shape:SolidMolecular weight:484.4Ref: TM-T4338
1mg40.00€5mg96.00€10mg152.00€25mg268.00€50mg429.00€100mg703.00€200mg954.00€1mL*10mM (DMSO)94.00€SAR407899
CAS:SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.Formula:C14H16N2O2Purity:99.42%Color and Shape:SolidMolecular weight:244.29Ref: TM-T7391
2mg34.00€5mg50.00€10mg75.00€25mg128.00€50mg200.00€100mg319.00€200mg474.00€1mL*10mM (DMSO)55.00€Mps1-IN-3 hydrochloride
Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.Formula:C26H32ClN7O4SColor and Shape:SolidMolecular weight:574.09JNJ-7706621
CAS:JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formula:C15H12F2N6O3SPurity:99.1% - 99.85%Color and Shape:SolidMolecular weight:394.36Ref: TM-T6126
1mg48.00€5mg100.00€10mg155.00€25mg268.00€50mg432.00€100mg595.00€200mg833.00€1mL*10mM (DMSO)94.00€Amenamevir
CAS:Amenamevir (ASP2151) is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2 (EC50: 14 ng/mLFormula:C24H26N4O5SPurity:99.00% - 99.86%Color and Shape:SolidMolecular weight:482.55Ref: TM-T4226
1mg34.00€5mg71.00€10mg92.00€25mg152.00€50mg222.00€100mg334.00€200mg494.00€1mL*10mM (DMSO)52.00€Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Formula:C30H57N7O10Purity:98.84%Color and Shape:SolidMolecular weight:675.81Tipiracil
CAS:Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.Formula:C9H11ClN4O2Purity:99.815%Color and Shape:SolidMolecular weight:242.66LXW7
CAS:LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formula:C29H48N12O12S2Purity:>99.99%Color and Shape:SolidMolecular weight:820.89POL1-IN-1
CAS:POL1-IN-1 (Compound 3A) 是一种RNA 聚合酶 1 POL1抑制剂，IC50值低于 0.5 uM。 它能有效抑制A375恶性黑色素瘤细胞系中RNA 聚合酶I 的转录。
Formula:C21H20N6Purity:98% - 98.01%Color and Shape:SolidMolecular weight:356.42Acelarin
CAS:Acelarin (NUC-1031) (NUC-1031) is a ProTide enhancement and transformation of the nucleoside analog, gemcitabine.
Formula:C25H27F2N4O8PPurity:99.26%Color and Shape:SolidMolecular weight:580.47Hesperadin
CAS:Hesperadin(IC50=250 nM) effectively inhibits Aurora B.Formula:C29H32N4O3SPurity:98.04% - 99.44%Color and Shape:SolidMolecular weight:516.653-Deazauridine
CAS:3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Formula:C10H13NO6Purity:99.86%Color and Shape:SolidMolecular weight:243.21
