Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase(114 products)
- CDK(543 products)
- Cell Cycle Arrest(5 products)
- Chk(47 products)
- DYRK(48 products)
- Dynamin(27 products)
- Ferroptosis(226 products)
- HSP(179 products)
- Integrin(228 products)
- Kinesin(88 products)
- LIM Kinase(20 products)
- Microtubule Associated(273 products)
- PKC(119 products)
- PLK(25 products)
- ROCK(63 products)
- Rho(6 products)
- Wee1(14 products)
- c-Myc(76 products)
Show 10 more subcategories
Found 3826 products of "Cell Cycle/Checkpoint"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
GSK-25
CAS:GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K, and a dramatically improved P450 profile.Formula:C24H16Cl2F2N6OPurity:98.59%Color and Shape:SolidMolecular weight:513.33Ref: TM-T4488
1mg47.00€2mg59.00€5mg92.00€10mg117.00€25mg172.00€50mg271.00€100mg454.00€1mL*10mM (DMSO)95.00€CHR-6494
CAS:CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).Formula:C16H16N6Purity:98.78%Color and Shape:SolidMolecular weight:292.34Ref: TM-T14959
5mg54.00€10mg82.00€25mg145.00€50mg259.00€100mg442.00€200mg643.00€1mL*10mM (DMSO)60.00€TAK-960 hydrochloride
CAS:TAK-960 hydrochloride is an oral, potent PLK1 inhibitor with IC50 of 0.8 nM, effective against various tumor cells and xenografts.Formula:C27H35ClF3N7O3Color and Shape:SolidMolecular weight:598.06Dasabuvir sodium
CAS:Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).Formula:C26H26N3NaO5SColor and Shape:SolidMolecular weight:515.56Brr2-IN-3
CAS:Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.Formula:C24H20N4O3SPurity:99.26%Color and Shape:SolidMolecular weight:444.51Ref: TM-T22282
1mg52.00€2mg65.00€5mg92.00€10mg161.00€25mg290.00€50mg420.00€100mg587.00€200mg792.00€1mL*10mM (DMSO)110.00€Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Formula:C23H15F2NO2Purity:99.1% - 99.57%Color and Shape:SolidMolecular weight:375.37Arginine-glycine-aspartic acid
CAS:RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formula:C12H22N6O6Purity:99.11%Color and Shape:SolidMolecular weight:346.34ML367
CAS:ML367 inhibits ATAD5 stabilization with low micromolar activity, serving as a probe molecule.Formula:C19H12F2N4Purity:99.39%Color and Shape:SolidMolecular weight:334.32S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Formula:C22H21NO2SPurity:97.02%Color and Shape:Almost White To Light Yellow Granular PowderMolecular weight:363.47NU6027
CAS:NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-Formula:C11H17N5O2Purity:98.36%Color and Shape:SolidMolecular weight:251.29M2I-1
CAS:M2I-1 inhibits Mad2 binding to Cdc20, disrupting SAC-related PPI and Mad2 dynamics, blocks Mad2-F-Mbp1 in FP assays.Formula:C19H24N4O4SPurity:99.02% - >99.99%Color and Shape:SolidMolecular weight:404.48Bonafton
CAS:Bonafton (Bonaphthone) is an antiviral agent.Formula:C10H5BrO2Purity:97.16%Color and Shape:SolidMolecular weight:237.05Ref: TM-T8877
1mg56.00€5mg118.00€10mg167.00€25mg281.00€50mg421.00€100mg605.00€200mg845.00€1mL*10mM (DMSO)92.00€Poloxin
CAS:Poloxin is a non-ATP competitive Polo-like Kinase 1 inhibitor. It targets the polo-box domain (IC50: appr 4.8 μM).Formula:C18H19NO3Purity:99.19%Color and Shape:SolidMolecular weight:297.35RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formula:C22H16ClN3OPurity:99.95%Color and Shape:SolidMolecular weight:373.83BS-181 hydrochloride
CAS:BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM.Formula:C22H32N6·HClPurity:99.21%Color and Shape:SolidMolecular weight:416.99Ref: TM-T6162
1mg37.00€2mg52.00€5mg79.00€10mg116.00€25mg250.00€50mg416.00€100mg645.00€200mgTo inquire1mL*10mM (DMSO)87.00€Cdk5 Substrate acetate
Cdk5, a serine/threonine kinase active in neurons, phosphorylates proteins like histone H1; its synthetic substrate has a Km of 5 µM.Formula:C55H103N15O14Purity:96.21%Color and Shape:SolidMolecular weight:1198.5Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Formula:C17H24ClNO4Purity:99.75%Color and Shape:SolidMolecular weight:341.83Pyridostatin hydrochloride
CAS:Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.Formula:C31H37Cl5N8O5Color and Shape:SolidMolecular weight:778.943-Deazauridine
CAS:3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Formula:C10H13NO6Purity:99.86%Color and Shape:SolidMolecular weight:243.21Preq1-Dihydrochloride
CAS:Preq1-Dihydrochloride, a queuosine pathway intermediate, binds strongly to PreQ1 riboswitch aptamer, suppressing protein expression.Formula:C7H11Cl2N5OPurity:99.46%Color and Shape:SolidMolecular weight:252.1
