Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
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Subcategories of "Cell Cycle/Checkpoint"
Aurora Kinase
CDK
Cell Cycle Arrest
Chk
DYRK
Dynamin
Ferroptosis
HSP
Integrin
KSP
Kinesin
LIM Kinase
Microtubule Associated
PKC
PLK
ROCK
Rho
Wee1
c-Myc
Show 11 more subcategories
Products of "Cell Cycle/Checkpoint"
CDK2/Bcl2-IN-1
CDK2/Bcl2-IN-1 (compound 1) is a saponin-based inhibitor of CDK-2 (IC50=117.6 nM) that exhibits potent cytotoxic …
Formula:
C35H56O10S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
668.88
Ref: TM-T78813
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
Avotaciclib hydrochloride
Avotaciclib hydrochloride, a CDK1 inhibitor, is the hydrochloride salt of Avotaciclib and exhibits potential therapeutic …
Formula:
C13H12ClN7O
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
317.73
Ref: TM-T78137
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
Visugromab
CAS:2556646-63-8
Visugromab, a GDF-15 neutralizing IgG4 monoclonal antibody (mAb), demonstrates potent efficacy in treating PD-1/PD-L1 relapsed/refractory …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T80863
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
Moloney murine leukemia virus RT
Moloney murine leukemia virus reverse transcriptase (MMLV RT) is a monomeric replicative polymerase intrinsic to …
Purity:
98%
Ref: TM-T79921
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
PKMYT1-IN-3
PKMYT1-IN-3 (compound 8ma) is a potent, selective inhibitor of PKMYT1, demonstrating an IC50 of 16.5 …
Formula:
C24H26FN5O2
Color and Shape:
Liquid
Molecular weight:
435.49
Ref: TM-T200211
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
Sintilimab
CAS:2072873-06-2
Sintilimab (IBI308), an IgG4 monoclonal antibody, blocks PD-1, enhancing T-cell anti-tumor response; treats Hodgkin's, lung, …
Purity:
> 95%
Color and Shape:
Liquid
Molecular weight:
144.04 kDa
Ref: TM-T35394
| 1mg | 158.00 € | ||
| 5mg | 398.00 € | ||
| 10mg | 685.00 € | ||
| 25mg | 1,012.00 € | ||
| 50mg | 1,390.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
2-Methylbutyrylcarnitine chloride
2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating …
Formula:
C12H24ClNO4
Color and Shape:
Liquid
Molecular weight:
281.78
Ref: TM-T200397
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
AURKA against 1
Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase …
Formula:
C28H32FN9O2
Color and Shape:
Liquid
Molecular weight:
545.61
Ref: TM-T89903
| 10mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
hDHODH-IN-12
hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of …
Formula:
C22H15F3N4O3
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
440.37
Ref: TM-T78932
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
CDK2-IN-19
CDK2-IN-19 (Compound 32) is a selective, orally active inhibitor of CDK2 (K i: 0.18 nM) …
Formula:
C20H21FN6O4S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
460.48
Ref: TM-T79648
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
Cirtuvivint
CAS:2143917-62-6
Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be …
Formula:
C24H25N7O
Purity:
100% - 100%
Color and Shape:
Solid
Molecular weight:
427.5
Ref: TM-T39608
| 1mg | 103.00 € | ||
| 5mg | 245.00 € | ||
| 10mg | 368.00 € | ||
| 25mg | 737.00 € | ||
| 50mg | 1,074.00 € | ||
| 100mg | 1,445.00 € | ||
| 500mg | 2,822.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Abciximab
CAS:143653-53-6
Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.
Purity:
SDS-PAGE:95.2%;SEC-HPLC:95.9%
Color and Shape:
Liquid
Molecular weight:
95.18 kDa
Ref: TM-T76844
| 1mg | 198.00 € | ||
| 5mg | 523.00 € | ||
| 10mg | 823.00 € | ||
| 25mg | 1,234.00 € | ||
| 50mg | 1,652.00 € | ||
| 100mg | 2,255.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
SP-96
CAS:2682114-54-9
SP-96: Aurora B inhibitor, IC50=0.316 nM, selectively hinders MDA-MD-468 growth, GI50=107 nM, for triple-negative breast …
Formula:
C25H20FN7O
Purity:
99.52%
Color and Shape:
Solid
Molecular weight:
453.47
Ref: TM-T41256
| 1mg | 73.00 € | ||
| 5mg | 159.00 € | ||
| 10mg | 247.00 € | ||
| 25mg | 482.00 € | ||
| 50mg | 701.00 € | ||
| 100mg | 985.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
CDK9-Cyclin T1 PPI-IN-1
CDK9-Cyclin T1 PPI-IN-1 (Compound B19) is a selective inhibitor of the CDK9-Cyclin T1 protein-protein interaction …
Purity:
98%
Ref: TM-T82758
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
Pidilizumab
CAS:1036730-42-3
Pidilizumab (CT-011), a humanized IgG1κ anti-PD-1 monoclonal antibody, serves as a DLL1 antagonist with potential …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T81461
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
Farletuzumab
CAS:896723-44-7
Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.
Purity:
> 95%
Color and Shape:
Liquid
Molecular weight:
145.36 kDa
Ref: TM-T76720
| 1mg | 346.00 € | ||
| 5mg | 866.00 € | ||
| 10mg | 1,383.00 € | ||
| 25mg | 2,032.00 € | ||
| 50mg | 2,757.00 € | ||
| 100mg | 3,647.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
CAF-382
CAF-382 (compound B1), an analog of SNS-032, functions as a CDKL5 and pan-CDK inhibitor, exhibiting …
Formula:
C16H22N4O2S2
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
366.5
Ref: TM-T79606
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
ART558
CAS:2603528-97-6
ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor …
Formula:
C21H21F3N4O2
Purity:
99.18%
Color and Shape:
Solid
Molecular weight:
418.41
Ref: TM-T9275
| 1mg | 157.00 € | ||
| 5mg | 384.00 € | ||
| 10mg | 574.00 € | ||
| 25mg | 915.00 € | ||
| 50mg | 1,240.00 € | ||
| 100mg | 1,663.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Eg5-IN-1
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an …
Formula:
C23H16ClFN4O
Purity:
98.21%
Color and Shape:
Liquid
Molecular weight:
418.85
Ref: TM-T77586
| 1mg | 182.00 € | ||
| 5mg | 449.00 € | ||
| 10mg | 643.00 € | ||
| 25mg | 1,007.00 € | ||
| 50mg | 1,384.00 € | ||
| 100mg | 1,828.00 € | ||
| 500mg | 3,664.00 € |
Estimated delivery in United States, on Friday 13 Dec 2024
Danburstotug
CAS:2307144-65-4
Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 …
Purity:
98%
Color and Shape:
Liquid
Ref: TM-T82613
| 1mg | To inquire | ||
| 5mg | To inquire |
Estimated delivery in United States, on Friday 13 Dec 2024
