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CDK
Samuraciclib hydrochloride
CAS:1805789-54-1
Samuraciclib hydrochloride is a potent, selective, ATP competitive and oral active CDK7 inhibitor with IC50 …
Formula:
C22H31ClN6O
Purity:
98.99%
Color and Shape:
Solid
Molecular weight:
430.97
Estimated delivery in United States, on Tuesday 1 Feb 2022
BRD6989
CAS:642008-81-9
BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and …
Formula:
C16H16N4
Purity:
98.82%
Color and Shape:
Solid
Molecular weight:
264.33
Estimated delivery in United States, on Tuesday 1 Feb 2022
Ribociclib succinate
CAS:1374639-75-4
Ribociclib succinate is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). …
Formula:
C27H36N8O5
Purity:
99.57%
Color and Shape:
Solid
Molecular weight:
552.63
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDC4297
CAS:1453834-21-3
LDC4297 is a potent and selective CDK7 inhibitor.
Formula:
C23H28N8O
Molecular weight:
432.52
Estimated delivery in United States, on Tuesday 1 Feb 2022
SY-1365
CAS:1816989-16-8
SY-1365 is a highly selective covalent CDK7 inhibitor. SY-1365 possesses therapeutic potential in both hematological …
Formula:
C31H35ClN8O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
587.12
Estimated delivery in United States, on Tuesday 1 Feb 2022
CAN508
CAS:140651-18-9
CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It …
Formula:
C9H10N6O
Molecular weight:
218.22
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDC000067
CAS:1073485-20-7
LDC000067 is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 …
Formula:
C18H18N4O3S
Purity:
99.07%
Color and Shape:
solid
Molecular weight:
370.43
Estimated delivery in United States, on Tuesday 1 Feb 2022
FIT-039
CAS:1113044-49-7
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin …
Formula:
C17H18FN3S
Molecular weight:
315.41
Estimated delivery in United States, on Tuesday 1 Feb 2022
SU-9516
CAS:666837-93-0
SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.
Formula:
C13H11N3O2
Molecular weight:
241.24
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK4/6-IN-4
CAS:2138499-06-4
CDK4/6-IN-4 is a selective CDK4/6 inhibitor and the active metabolite of Abemaciclib.
Formula:
C27H32F2N8O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
522.59
Estimated delivery in United States, on Tuesday 1 Feb 2022
1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester
CAS:2326428-25-3
1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester is a novel CDK7 inhibitors.
Formula:
C26H39N7O3
Molecular weight:
497.64
Estimated delivery in United States, on Tuesday 1 Feb 2022
CLK-IN-T3
CAS:2109805-56-1
CLK-IN-T3 is a potent inhibitor of CDC-like kinase (CLK) (IC50s: 0.67 nM, 15 nM, and …
Formula:
C28H30N6O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
482.58
Estimated delivery in United States, on Tuesday 1 Feb 2022
Purvalanol B
CAS:212844-54-7
Purvalanol B is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin …
Formula:
C20H25ClN6O3
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
432.9
Estimated delivery in United States, on Tuesday 1 Feb 2022
Simurosertib
CAS:1330782-76-7
Simurosertib is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: <0.3 nM).
Formula:
C17H19N5OS
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
341.43
Estimated delivery in United States, on Tuesday 1 Feb 2022
NS13001
CAS:1063331-94-1
NS13001 is a potent, selective, orally active allosteric positive modulator of SK channels (small conductance …
Formula:
C17H16ClN7
Purity:
99.55%
Color and Shape:
solid
Molecular weight:
353.81
Estimated delivery in United States, on Tuesday 1 Feb 2022
AS2863619
CAS:2241300-51-4
AS2863619 is an orally active inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19 (IC50s of …
Formula:
C16H14Cl2N8O
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
405.24
Estimated delivery in United States, on Tuesday 1 Feb 2022
(±)-BAY-1251152
CAS:1610358-53-6
(±)-BAY-1251152 is a racemic mixture of BAY-1251152. BAY-1251152 is highly selective inhibitor of PTEF/CDK9.
Formula:
C19H18F2N4O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
404.43
Estimated delivery in United States, on Tuesday 1 Feb 2022
Trilaciclib hydrochloride
CAS:1977495-97-8
Trilaciclib hydrochloride is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 …
Formula:
C24H32Cl2N8O
Purity:
99.69%
Color and Shape:
Solid
Molecular weight:
519.47
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK9-IN-9
CAS:2246956-84-1
CDK9-IN-9 is a potent and selective CDK9 inhibitor (IC50: 1.8 nM) with anti-cancer activity. It …
Formula:
C22H23F2N5O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
459.51
Estimated delivery in United States, on Tuesday 1 Feb 2022
PROTAC CDK2/9 Degrader-1
CAS:2408641-24-5
PROTAC CDK2/9 Degrader-1 is a potent CDK2 and CDK9 dual degrader(DC50 of 62 nM and …
Formula:
C40H41N13O7
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
815.84
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK8-IN-4
CAS:1613638-82-6
CDK8-IN-4 is an inhibitor of CDK8 (IC50: 0.2 nM).
Formula:
C20H18N4O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
330.38
Estimated delivery in United States, on Tuesday 1 Feb 2022
Palbociclib hydrochloride
CAS:827022-32-2
Palbociclib (PD-0332991) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition …
Formula:
C24H29N7O2·HCl
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
483.99
Estimated delivery in United States, on Tuesday 1 Feb 2022
Abemaciclib Metabolites M2
CAS:1231930-57-6
Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 …
Formula:
C25H28F2N8
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
478.54
Estimated delivery in United States, on Tuesday 1 Feb 2022
WHI-P180
CAS:211555-08-7
WHI-P180 is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, …
Formula:
C16H15N3O3
Purity:
97.74%
Color and Shape:
solid
Molecular weight:
297.31
Estimated delivery in United States, on Tuesday 1 Feb 2022
PF-06873600
CAS:2185857-97-8
PF-06873600 is a selective and orally bioavailable cyclin-dependent kinase (CDK) inhibitor(CDK2, CDK4 and CDK6 with …
Formula:
C20H27F2N5O4S
Purity:
98.77%
Color and Shape:
Solid
Molecular weight:
471.52
Estimated delivery in United States, on Tuesday 1 Feb 2022
Tricin
CAS:520-32-1
Tricin can inhibit human cytomegalovirus (HCMV) replication by inhibiting CDK9. Tricin inhibits the proliferation and …
Formula:
C17H14O7
Molecular weight:
330.29
Estimated delivery in United States, on Tuesday 1 Feb 2022
THZ1
CAS:1604810-83-4
THZ1 is a novel selective and potent covalent CDK7 inhibitor.
Formula:
C31H28ClN7O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
566.05
Estimated delivery in United States, on Tuesday 1 Feb 2022
Cdc7-IN-1
CAS:1402055-25-7
Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM …
Formula:
C21H16ClN3O4
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
409.82
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDKI-73
CAS:1421693-22-2
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL …
Formula:
C15H15FN6O2S2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
394.45
Estimated delivery in United States, on Tuesday 1 Feb 2022
LY2835219
CAS:1231930-82-7
LY2835219 is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM).
Formula:
C27H32F2N8·CH4O3S
Purity:
99.10%
Color and Shape:
solid
Molecular weight:
602.7
Estimated delivery in United States, on Tuesday 1 Feb 2022
AS2863619 free base
CAS:2241300-50-3
AS2863619 free base enables the conversion of antigen-specific effector/memory T cells into Foxp3+ regulatory T …
Formula:
C16H12N8O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
332.32
Estimated delivery in United States, on Tuesday 1 Feb 2022
CLK1-IN-1
CAS:2123491-32-5
CLK1-IN-1 is a potent and selective inhibitor of the Cdc2-like kinase 1 (CLK1; IC50: 2 …
Formula:
C24H16FN5O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
409.42
Estimated delivery in United States, on Tuesday 1 Feb 2022
MSC2530818
CAS:1883423-59-3
MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).
Formula:
C18H17ClN4O
Purity:
99.33%
Color and Shape:
Solid
Molecular weight:
340.81
Estimated delivery in United States, on Tuesday 1 Feb 2022
Flavopiridol hydrochloride
CAS:131740-09-5
Alvocidib Hydrochloride is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, …
Formula:
C21H21Cl2NO5
Purity:
99.00%
Color and Shape:
solid
Molecular weight:
438.3
Estimated delivery in United States, on Tuesday 1 Feb 2022
6-(Dimethylamino)purine
CAS:938-55-6
6-(Dimethylamino)purine is a serine threonine protein kinase and CDK inhibitor
Formula:
C7H9N5
Purity:
99.49%
Color and Shape:
Solid
Molecular weight:
163.18
Estimated delivery in United States, on Tuesday 1 Feb 2022
Atuveciclib
Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb/CDK9 inhibitor. It inhibits CDK9/CycT1 (IC50: …
Formula:
C18H18FN5O2S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
387.43
Estimated delivery in United States, on Tuesday 1 Feb 2022
Roscovitine
CAS:186692-46-6
Roscovitine is a potent inhibitor of Cdk2/cyclin E (IC50: 0.1 µM). It also inhibits Cdk7/cyclin …
Formula:
C19H26N6O
Purity:
98.00%
Color and Shape:
White To Off-White Solid
Molecular weight:
354.45
Estimated delivery in United States, on Tuesday 1 Feb 2022
EHT 5372
CAS:1425945-60-3
EHT 5372 is a strong DYRKs family kinases of inhibitor (IC50s: 0.22, 0.28 nM for …
Formula:
C18H14FN5O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
383.4
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK2-IN-4
CAS:2079895-42-2
CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM …
Formula:
C23H18N6O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
442.49
Estimated delivery in United States, on Tuesday 1 Feb 2022
(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 …
Formula:
C24H25Cl2F3N4O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
513.38
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK4/6-IN-2
CAS:1800506-48-2
CDK4/6-IN-2 is a potent CDK4 and CDK6 inhibitor (IC50s: 2.7 and 16 nM) extracted from …
Formula:
C27H32F2N8
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
506.59
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK inhibitor II
CAS:1269815-17-9
CDK-IN-2 is a potent and specific CDK9 inhibitor (IC50: <8 nM).
Formula:
C18H19ClFN3O2
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
363.81
Estimated delivery in United States, on Tuesday 1 Feb 2022
XL413
CAS:1169558-38-6
XL-413 is an orally bioavailable cell division cycle 7 homolog (CDC7) kinase inhibitor with potential …
Formula:
C14H12ClN3O2
Purity:
98.0%
Color and Shape:
solid
Molecular weight:
289.06
Estimated delivery in United States, on Tuesday 1 Feb 2022
Roniciclib
CAS:1223498-69-8
Roniciclib is an inhibitor of pan-cyclin dependent kinase (IC50s: 5-25 nM for CDK1, CDK2, CDK3, …
Formula:
C18H21F3N4O3S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
430.44
Estimated delivery in United States, on Tuesday 1 Feb 2022
IIIM-290
CAS:2213468-64-3
IIIM-290 is an oral CDK inhibitor (IC50s: 90 and 94 nM for CDK2/A and CDK9/T1).
Formula:
C23H21Cl2NO5
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
462.32
Estimated delivery in United States, on Tuesday 1 Feb 2022
Ribociclib hydrochloride
CAS:1211443-80-9
Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). …
Formula:
C23H31ClN8O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
471
Estimated delivery in United States, on Tuesday 1 Feb 2022
Indomethacin-D4
CAS:87377-08-0
Indomethacin-D4 is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 …
Formula:
C19H12D4ClNO4
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
361.81
Estimated delivery in United States, on Tuesday 1 Feb 2022
THZ2
CAS:1604810-84-5
THZ2, an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential …
Formula:
C31H28ClN7O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
566.05
Estimated delivery in United States, on Tuesday 1 Feb 2022
Estimated delivery in United States, on Tuesday 1 Feb 2022
Bohemine
CAS:189232-42-6
Bohemine is a cyclin-dependent kinase inhibitor.
Formula:
C18H24N6O
Purity:
98.60%
Color and Shape:
solid
Molecular weight:
340.42
Estimated delivery in United States, on Tuesday 1 Feb 2022
Indoramin D5
CAS:57165-41-0
Indoramin D5 is a piperidine antiadrenergic agent. Indoramin D5 is deuterium labeled Indoramin.
Formula:
C22H20D5N3O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
352.48
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK8-IN-1
CAS:1629633-48-2
CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).
Formula:
C11H8F3N3O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
255.2
Estimated delivery in United States, on Tuesday 1 Feb 2022
K03861
CAS:853299-07-7
K03861 is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 …
Formula:
C24H26F3N7O2
Purity:
99.30%
Color and Shape:
solid
Molecular weight:
501.5
Estimated delivery in United States, on Tuesday 1 Feb 2022
T025
CAS:2407433-00-3
T025 is a highly potent and orally available inhibitor of Cdc2-like kinase (CLK)(Kds of 4.8, …
Formula:
C21H18N8
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
382.42
Estimated delivery in United States, on Tuesday 1 Feb 2022
LDC-4297 HCl (1453834-21-3(free base))
LDC4297 is a potent and selective CDK7 inhibitor with an IC50 of 0.13 nM.
Formula:
C23H29ClN8O
Purity:
99.81%
Color and Shape:
solid
Molecular weight:
469.02
Estimated delivery in United States, on Tuesday 1 Feb 2022
FN-1501
CAS:1429515-59-2
FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM …
Formula:
C22H25N9O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
431.49
Estimated delivery in United States, on Tuesday 1 Feb 2022
SR-4835
CAS:2387704-62-1
SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; …
Formula:
C21H20Cl2N10O
Purity:
100.00%
Color and Shape:
Solid
Molecular weight:
499.36
Estimated delivery in United States, on Tuesday 1 Feb 2022
FMF-04-159-2
CAS:2364489-81-4
FMF-04-159-2 inhibits CDK14 and CDK2 with IC50s of 39.6 nM and 256 nM in NanoBRET …
Formula:
C28H30Cl3N7O5S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
683.01
Estimated delivery in United States, on Tuesday 1 Feb 2022
BS194
CAS:1092443-55-4
BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.
Formula:
C20H27N5O3
Purity:
99.64%
Color and Shape:
solid
Molecular weight:
385.46
Estimated delivery in United States, on Tuesday 1 Feb 2022
(R)-CR8 trihydrochloride
CAS:1786438-30-9
(R)-CR8 trihydrochloride is a potent inhibitor CDK1/2/5/7/9.
Formula:
C24H32Cl3N7O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
540.92
Estimated delivery in United States, on Tuesday 1 Feb 2022
GW779439X
CAS:551919-98-3
GW779439X is an inhibitor of CDK.
Formula:
C22H21F3N8
Color and Shape:
Solid
Molecular weight:
454.45
Estimated delivery in United States, on Tuesday 1 Feb 2022
BS-181 HCl
CAS:1397219-81-6
BS-181 HCl is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is …
Formula:
C22H32N6·HCl
Purity:
99.97%
Color and Shape:
solid
Molecular weight:
416.99
Estimated delivery in United States, on Tuesday 1 Feb 2022
Furanodiene
CAS:19912-61-9
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
Formula:
C15H20O
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
216.15
Estimated delivery in United States, on Tuesday 1 Feb 2022
JNJ-39758979 dihydrochloride
JNJ-39758979 dihydrochloride functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. …
Formula:
C11H21Cl2N5
Molecular weight:
294.22
Estimated delivery in United States, on Tuesday 1 Feb 2022
1 nM-PP1
CAS:221244-14-0
1 nM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor …
Formula:
C20H21N5
Purity:
98.93%
Color and Shape:
White Cyrstalline Solid
Molecular weight:
331.41
Estimated delivery in United States, on Tuesday 1 Feb 2022
Atuveciclib Racemate
CAS:1414943-88-6
Atuveciclib is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an …
Formula:
C18H18FN5O2S
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
387.43
Estimated delivery in United States, on Tuesday 1 Feb 2022
CP-10
CAS:2366268-80-4
CP-10 is a PROTAC with highly selective and remarkable CDK6 degradation (DC50: 2.1 nM). It …
Formula:
C44H49N13O7
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
871.94
Estimated delivery in United States, on Tuesday 1 Feb 2022
(R)-CR8
CAS:294646-77-8
(R)-CR8 is a potent and selective CDK inhibitor.
Formula:
C24H29N7O
Purity:
98.41%
Color and Shape:
solid
Molecular weight:
431.53
Estimated delivery in United States, on Tuesday 1 Feb 2022
TP-353
CAS:1253799-29-9
TP353 is a CDK7 inhibitor.
Formula:
C35H30FNO3
Purity:
99.98%
Color and Shape:
solid
Molecular weight:
531.62
Estimated delivery in United States, on Tuesday 1 Feb 2022
Trilaciclib
CAS:1374743-00-6
Trilaciclib is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and …
Formula:
C24H30N8O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
446.55
Estimated delivery in United States, on Tuesday 1 Feb 2022
BSJ-4-116
CAS:2519823-34-6
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 …
Formula:
C40H49ClN8O8S
Molecular weight:
837.38
Estimated delivery in United States, on Tuesday 1 Feb 2022
Voruciclib hydrochloride
CAS:1000023-05-1
Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).
Formula:
C22H20Cl2F3NO5
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
506.3
Estimated delivery in United States, on Tuesday 1 Feb 2022
AG-024322
CAS:837364-57-5
AG-024322 is a potent ATP-competitive inhibitor of pan-CDK against cell cycle kinases CDK1, CDK2, and …
Formula:
C23H20F2N6
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
418.44
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK4/6/1 Inhibitor
CAS:2099128-41-1
CDK4/6/1 Inhibitor is a CDK4/6 inhibitor (IC50s: 3 and 1 nM).
Formula:
C28H30F2N6
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
488.57
Estimated delivery in United States, on Tuesday 1 Feb 2022
MBQ-167
CAS:2097938-73-1
MBQ-167 is a dual inhibitor of Rac/Cdc42 (IC50s: 103 nM for Rac 1/2/3 and 78 …
Formula:
C22H18N4
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
338.41
Estimated delivery in United States, on Tuesday 1 Feb 2022
Palbociclib D8
CAS:1628752-83-9
Palbociclib D8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active inhibitor …
Formula:
C24H21D8N7O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
455.58
Estimated delivery in United States, on Tuesday 1 Feb 2022
Men 10376
CAS:135306-85-3
Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of …
Formula:
C57H68N12O10
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
1081.22
Estimated delivery in United States, on Tuesday 1 Feb 2022
ALSTERPAULLONE
CAS:237430-03-4
Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec
Formula:
C16H11N3O3
Purity:
99.39%
Color and Shape:
solid
Molecular weight:
293.28
Estimated delivery in United States, on Tuesday 1 Feb 2022
Purvalanol A
CAS:212844-53-6
Purvalanol A is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for …
Formula:
C19H25ClN6O
Purity:
98.13%
Color and Shape:
Powder
Molecular weight:
388.89
Estimated delivery in United States, on Tuesday 1 Feb 2022
SEL120-34A
CAS:1609522-33-9
SEL120-34A is a selective, orally available, and ATP-competitive CDK8 inhibitor (IC50s: 4.4 nM and 10.4 …
Formula:
C15H18Br2N4
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
414.14
Estimated delivery in United States, on Tuesday 1 Feb 2022
CID44216842
CAS:1222513-26-9
CID44216842 is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT …
Formula:
C22H20BrN3O3S
Purity:
99.63%
Molecular weight:
486.38
Estimated delivery in United States, on Tuesday 1 Feb 2022
THAL-SNS-032
CAS:2139287-33-3
THAL-SNS-032 is a selective CDK9 degrader PROTAC.
Formula:
C40H52N8O10S2
Purity:
99.68%
Color and Shape:
Solid
Molecular weight:
869.02
Estimated delivery in United States, on Tuesday 1 Feb 2022
Ribociclib
CAS:1211441-98-3
LEE011 is an orally available, and highly specific CDK4/6 inhibitor (IC5010/39 nM).
Formula:
C23H30N8O
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
434.54
Estimated delivery in United States, on Tuesday 1 Feb 2022
SEL120-34A HCl
CAS:1609452-30-3
SEL120-34A HCl is a selective, orally available and ATP-competitive inhibitor of CDK8(CDK8/CycC and CDK19/CycC with …
Formula:
C15H18Br2N4xHCl
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
N/A
Estimated delivery in United States, on Tuesday 1 Feb 2022
Indirubin-3-monoxime
CAS:667463-82-3
Indirubin-3-monoxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role …
Formula:
C16H11N3O2
Purity:
98.26%
Molecular weight:
277.28
Estimated delivery in United States, on Tuesday 1 Feb 2022
THZ1-R
CAS:1621523-07-6
THZ1-R displays diminished activity for CDK7 inhibition(Kd:142 nM).
Formula:
C31H30ClN7O2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
568.07
Estimated delivery in United States, on Tuesday 1 Feb 2022
PNU 112455A
CAS:21886-12-4
PNU 112455A is an ATP site competetive inhibitor of CDK2 and CDK5,binds to the ATP …
Formula:
C10H12ClN5O2S
Purity:
100.00%
Color and Shape:
solid
Molecular weight:
301.75
Estimated delivery in United States, on Tuesday 1 Feb 2022
CC671
CAS:1618658-88-0
CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.
Formula:
C28H28N6O4
Purity:
98.65%
Color and Shape:
Solid
Molecular weight:
512.56
Estimated delivery in United States, on Tuesday 1 Feb 2022
JSH-150
CAS:2247481-21-4
JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).
Formula:
C24H33ClN6O2S
Purity:
99.96%
Color and Shape:
Solid
Molecular weight:
505.08
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK12-IN-3
CAS:2220184-50-7
CDK12-IN-3 is a selective CDK12 inhibitor (IC50: 491 nM in an enzymatic assay).
Formula:
C23H28F2N8O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
470.52
Estimated delivery in United States, on Tuesday 1 Feb 2022
ON-013100
CAS:865783-95-5
ON-013100 is an antineoplastic drug. It also acts as a mitotic inhibitor that could inhibit …
Formula:
C19H22O7S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
394.44
Estimated delivery in United States, on Tuesday 1 Feb 2022
THZ531
CAS:1702809-17-3
THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).
Formula:
C30H32ClN7O2
Purity:
99.86%
Color and Shape:
Solid
Molecular weight:
558.08
Estimated delivery in United States, on Tuesday 1 Feb 2022
Lappaol F
CAS:69394-17-8
1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity …
Formula:
C40H42O12
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
714.8
Estimated delivery in United States, on Tuesday 1 Feb 2022
SCH900776
CAS:891494-63-6
CHK1 Inhibitor MK-8776 is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential …
Formula:
C15H18BrN7
Purity:
99.60%
Color and Shape:
solid
Molecular weight:
376.25
Estimated delivery in United States, on Tuesday 1 Feb 2022
MLS-573151
CAS:10179-57-4
MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against …
Formula:
C21H19N3O2S
Molecular weight:
377.46
Estimated delivery in United States, on Tuesday 1 Feb 2022
CDK8/19-IN-1
CAS:1818427-07-4
CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, …
Formula:
C19H18N4O4S2
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
430.5
Estimated delivery in United States, on Tuesday 1 Feb 2022
Lerociclib dihydrochloride
CAS:2097938-59-3
Lerociclib dihydrochloride is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 2 nM …
Formula:
C26H36Cl2N8O
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
547.52
Estimated delivery in United States, on Tuesday 1 Feb 2022
Atuveciclib S-Enantiomer
Atuveciclib (BAY-1143572) S-enantiomer is a potent and selective CDK9 inhibitor (IC50: 16 nM for CDK9/CycT1).
Formula:
C18H18FN5O2S
Purity:
98.00%
Color and Shape:
solid
Molecular weight:
387.43
Estimated delivery in United States, on Tuesday 1 Feb 2022
Lerociclib
CAS:1628256-23-4
Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 2nM, 1 …
Formula:
C26H34N8O
Purity:
98.00%
Color and Shape:
Solid
Molecular weight:
474.6
Estimated delivery in United States, on Tuesday 1 Feb 2022
YKL-5-124
CAS:1957203-01-8
YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 …
Formula:
C28H33N7O3
Color and Shape:
Solid
Molecular weight:
515.61
Estimated delivery in United States, on Tuesday 1 Feb 2022
