PKC
PKC (Protein Kinase C) inhibitors target the PKC family of serine/threonine kinases, which are involved in a wide range of cellular processes, including cell cycle regulation, apoptosis, and differentiation. PKC plays a key role in signal transduction pathways that influence cell proliferation and survival. Inhibiting PKC can lead to changes in cell cycle progression, making these inhibitors valuable in research related to cancer, neurobiology, and cardiovascular diseases. At CymitQuimica, we provide a diverse selection of high-quality PKC inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Found 124 products of "PKC"
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Aurothiomalate tetramer sodium
Aurothiomalate tetramer sodium, a tetrameric form of Aurothiomalate sodium, functions as an anti-arthritis gold agent. It also acts as a potent and selective inhibitor of the oncogenic PKCι signaling pathway.Color and Shape:Odour SolidPKCδ Peptide Substrate
CAS:PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) andFormula:C109H191N35O29SColor and Shape:SolidMolecular weight:2487.97Protein kinase C α peptide TFA
CAS:Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase.Formula:C68H115F3N24O26SColor and Shape:SolidMolecular weight:1773.85NPC-15437 dihydrochloride
CAS:NPC-15437 dihydrochloride is a PKC inhibitor blocking enzyme activity and phorbol ester binding, selective over other kinases, in cellular signaling research.Formula:C25H52Cl2N4O2Color and Shape:SolidMolecular weight:511.62K-252b
CAS:K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.
Formula:C26H19N3O5Purity:98%Color and Shape:Ready-To-Use SolutionMolecular weight:453.45(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formula:C39H72O5Color and Shape:SolidMolecular weight:620.99PKC-θ inhibitor
CAS:PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.Formula:C20H25F3N6O3Purity:99.46%Color and Shape:SolidMolecular weight:454.45Ref: TM-T5423
1mg101.00€5mg236.00€10mg313.00€25mg442.00€50mg580.00€100mg893.00€200mg1,198.00€1mL*10mM (DMSO)259.00€Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Formula:C14H19Cl2N3O2SPurity:99.81%Color and Shape:White Crystalline SolidMolecular weight:364.29[Ala107]-MBP (104-118) acetate
[Ala107]-MBP (104-118) acetate ([Ala107]-MBP ) is synthetic peptide analog of bovine myelin basic protein (MBP).Formula:C59H108N20O21Purity:99.23%Color and Shape:SolidMolecular weight:1553.72PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formula:C21H22N6OPurity:98.82%Color and Shape:SolidMolecular weight:374.44Ref: TM-T8764
1mg107.00€2mg152.00€5mg219.00€10mg349.00€25mg583.00€50mg833.00€100mg1,134.00€500mg2,268.00€1mL*10mM (DMSO)226.00€Taurochenodeoxycholic Acid
CAS:Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formula:C26H45NO6SPurity:99.53% - 99.86%Color and Shape:SolidMolecular weight:499.7Valrubicin
CAS:Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.Formula:C34H36F3NO13Purity:98.63%Color and Shape:SolidMolecular weight:723.64Go 6983
CAS:Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!Formula:C26H26N4O3Purity:98.41% - 99.85%Color and Shape:SolidMolecular weight:442.51Ref: TM-T6313
1mg40.00€2mg52.00€5mg79.00€10mg119.00€25mg233.00€50mg368.00€100mg533.00€1mL*10mM (DMSO)84.00€Darovasertib
CAS:Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).Formula:C22H23F3N8OPurity:98.72% - ≥95%Color and Shape:SolidMolecular weight:472.47Taurochenodeoxycholic acid sodium
CAS:Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formula:C26H44NNaO6SPurity:98.23% - 99.56%Color and Shape:White To Off-White PowderMolecular weight:521.68Fasudil hydrochloride
CAS:Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.Formula:C14H18ClN3O2SPurity:99.54% - ≥95%Color and Shape:White SolidMolecular weight:327.83Verbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formula:C29H36O15Purity:97.46% - 99.55%Color and Shape:SolidMolecular weight:624.59Ref: TM-T3375
2mg39.00€5mg58.00€10mg88.00€25mg168.00€50mg255.00€100mg359.00€200mg525.00€1mL*10mM (DMSO)81.00€Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formula:C36H56O8Purity:98.55% - >99.99%Color and Shape:White To Off-White SolidMolecular weight:616.83Afuresertib hydrochloride
CAS:Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)
Formula:C18H18Cl3FN4OSPurity:99.96%Color and Shape:SolidMolecular weight:463.8TAS-301
CAS:TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.Formula:C23H19NO3Purity:99.55%Color and Shape:SolidMolecular weight:357.4Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:97.61% - >99.99%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg49.00€5mg84.00€10mg119.00€25mg205.00€50mg310.00€100mg462.00€500mg1,035.00€1mL*10mM (DMSO)90.00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Chelerythrine
CAS:1.Formula:C21H18NO4Purity:98.36% - 99.96%Color and Shape:SolidMolecular weight:348.37Sotrastaurin
CAS:Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).Formula:C25H22N6O2Purity:98% - 99.70%Color and Shape:SolidMolecular weight:438.48Ref: TM-T6278
1mg44.00€5mg86.00€10mg135.00€25mg254.00€50mg423.00€100mg605.00€200mg845.00€1mL*10mM (DMSO)94.00€Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formula:C19H20O5Purity:97.22% - 99.91%Color and Shape:SolidMolecular weight:328.36Ref: TM-T3S1416
1mg40.00€5mg84.00€10mg113.00€25mg245.00€50mg439.00€100mg627.00€500mg1,288.00€1mL*10mM (DMSO)93.00€Ζ-Stat
CAS:ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis inFormula:C10H8O10S3Purity:99.85%Color and Shape:SolidMolecular weight:384.36Chelerythrine chloride
CAS:Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect toFormula:C21H18ClNO4Purity:95% - 99.19%Color and Shape:Yellow To Orange SolidMolecular weight:383.83Ref: TM-T3419
2mg34.00€5mg50.00€10mg84.00€25mg145.00€50mg205.00€100mg289.00€200mg432.00€1mL*10mM (DMSO)65.00€R59949
CAS:R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.Formula:C28H25F2N3OSPurity:97.04%Color and Shape:SolidMolecular weight:489.58Ref: TM-T26019
1mg39.00€2mg52.00€5mg87.00€10mg138.00€25mg281.00€50mg425.00€100mg625.00€200mg883.00€1mL*10mM (DMSO)95.00€Taurolithocholic acid sodium salt
CAS:Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormula:C26H44NNaO5SPurity:99.79% - 99.93%Color and Shape:SolidMolecular weight:505.69Desmethylglycitein
CAS:Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormula:C15H10O5Purity:97.93%Color and Shape:SolidMolecular weight:270.24Hypocrellin A
CAS:Hypocrellin A is a natural PKC inhibitor with light-induced antitumor, antifungal and antiviral activities.Cost-effective and quality-assured.Formula:C30H26O10Purity:98% - 99.95%Color and Shape:SolidMolecular weight:546.52Bisindolylmaleimide V
CAS:Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.Formula:C21H15N3O2Purity:90%Color and Shape:Red SolidMolecular weight:341.36Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFormula:C28H26N4O3Purity:99.24% - 99.82%Color and Shape:Off-White PowderMolecular weight:466.53Ref: TM-T6680
1mg58.00€2mg82.00€5mg92.00€10mg138.00€25mg234.00€50mg380.00€100mg565.00€500mg1,215.00€1mL*10mM (DMSO)103.00€1,2-Dimyristoyl-sn-glycerol
CAS:1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..Formula:C31H60O5Purity:99.96%Color and Shape:White Powder With LumpsMolecular weight:512.81Hispidin
CAS:Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective propertiesFormula:C13H10O5Purity:98.27%Color and Shape:White Crystalline PowderMolecular weight:246.22Ref: TM-T7792
1mg88.00€5mg187.00€10mg298.00€25mg533.00€50mg747.00€100mg1,017.00€1mL*10mM (DMSO)207.00€HA-100
CAS:HA-100 is an inhibitor of protein kinaseFormula:C13H15N3O2SPurity:99.44%Color and Shape:Pale Yellow Crystalline SolidMolecular weight:277.34PKC ζ pseudosubstrate acetate
PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.Formula:C78H132N30O18Purity:98.78%Color and Shape:SolidMolecular weight:1778.10Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Formula:C25H24N4O2Purity:97.51% - 98.75%Color and Shape:Orange SolidMolecular weight:412.48Mitoxantrone
CAS:Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formula:C22H28N4O6Purity:96.29% - 98.74%Color and Shape:Blue PowderMolecular weight:444.48PKC-θ inhibitor hcl
CAS:PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).Formula:C20H26ClF3N6O3Purity:98.93%Color and Shape:SolidMolecular weight:490.91Ref: TM-T5817
1mg88.00€2mg114.00€5mg220.00€10mg356.00€25mg595.00€50mg848.00€100mg1,153.00€500mg2,305.00€Aurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Formula:C4H3AuNa2O4SPurity:99.66%Color and Shape:SoildMolecular weight:390.07Decursinol angelate
CAS:Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.Formula:C19H20O5Purity:99.93%Color and Shape:SolidMolecular weight:328.36Rottlerin
CAS:Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formula:C30H28O8Purity:97.41% - 99.44%Color and Shape:Orange To Brown PowderMolecular weight:516.54D-ERYTHRO-SPHINGOSINE
CAS:D-erythro-Sphingosine (trans-4-Sphingenine) is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activatorFormula:C18H37NO2Purity:98% - 99.85%Color and Shape:SolidMolecular weight:299.49Procyanidin A1
CAS:Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.Formula:C30H24O12Purity:99.52%Color and Shape:SolidMolecular weight:576.50Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFormula:C18H17Cl2FN4OSPurity:97.51% - 99.51%Color and Shape:SolidMolecular weight:427.32Ref: TM-T1911
1mg37.00€2mg52.00€5mg74.00€10mg92.00€25mg166.00€50mg259.00€100mg452.00€500mg982.00€1mL*10mM (DMSO)74.00€Bisindolylmaleimide IV
CAS:Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)
Formula:C20H13N3O2Purity:98.83%Color and Shape:Dark Red SolidMolecular weight:327.34TPPB
CAS:TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).
Formula:C27H30F3N3O3Purity:97.71% - 98.00%Color and Shape:SolidMolecular weight:501.54Ro 31-8220 Mesylate
CAS:Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.Formula:C25H23N5O2S·CH4O3SPurity:98.79% - 99.02%Color and Shape:SolidMolecular weight:553.65Ref: TM-T6643
1mg49.00€2mg64.00€5mg92.00€10mg150.00€25mg230.00€50mg319.00€100mg475.00€1mL*10mM (DMSO)133.00€
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