Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Found 2592 products of "Chromatin/Epigenetics"
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BMS-986158
CAS:BMS-986158: BET inhibitor, IC50 of 6.6 nM in SCLC, 5 nM in TNBC cells.Formula:C30H33N5O2Purity:98.78%Color and Shape:SolidMolecular weight:495.62Ref: TM-T14685
1mg87.00€5mg259.00€10mg465.00€25mg745.00€50mg1,026.00€100mg1,388.00€1mL*10mM (DMSO)283.00€BRD-6929
CAS:BRD-6929, a brain-targeted HDAC1/2 inhibitor (IC50 1/8 nM), enhances gnidimacrin's anti-HIV effect, useful in mood behavior studies.Formula:C19H17N3O2SPurity:98.01% - 99.05%Color and Shape:SolidMolecular weight:351.42Ref: TM-T10603
5mg48.00€10mg86.00€25mg166.00€50mg289.00€100mg419.00€200mg587.00€1mL*10mM (DMSO)49.00€LIN28 inhibitor LI71
CAS:LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM.Formula:C21H21NO3Purity:95.88%Color and Shape:SolidMolecular weight:335.4Ref: TM-T11850
1mg107.00€5mg255.00€10mg414.00€25mg745.00€50mg1,063.00€100mg1,459.00€1mL*10mM (DMSO)341.00€BRD 4354
CAS:BRD 4354 is an inhibitor of HDAC5 and HDAC9. For HDAC5 and HDAC9, the IC50s values are 0.85 and 1.88 μM, respectively.Formula:C21H23ClN4OPurity:99.86%Color and Shape:SolidMolecular weight:382.89Ref: TM-T10602L
1mg34.00€2mg44.00€5mg66.00€10mg92.00€25mg178.00€50mg308.00€100mg512.00€500mg1,071.00€1mL*10mM (DMSO)73.00€ODM-207
CAS:ODM-207 (BET-IN-4) is a potent BRD4 inhibitor.Formula:C22H21N3O3Purity:99.75%Color and Shape:SolidMolecular weight:375.42Ref: TM-T10521
1mg44.00€5mg92.00€10mg133.00€25mg235.00€50mg339.00€100mg480.00€200mg660.00€1mL*10mM (DMSO)90.00€Fenbendazole
CAS:Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.Formula:C15H13N3O2SPurity:99.74%Color and Shape:White To Yellowish PowderMolecular weight:299.351-Naphthohydroxamic acid
CAS:1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1Formula:C11H9NO2Purity:99.19%Color and Shape:SolidMolecular weight:187.19Ref: TM-T13996
5mg33.00€10mg60.00€25mg108.00€50mg200.00€100mg299.00€200mg430.00€1mL*10mM (DMSO)38.00€SIRT-IN-2
CAS:SIRT-IN-2 is a potent SIRT1/2/3 inhibitor(IC50s of 4, 1, 7 μM, respectively).Formula:C15H21N5O3S2Purity:98.26%Color and Shape:SolidMolecular weight:383.49Ref: TM-T12919
1mg92.00€5mg215.00€10mg344.00€25mg587.00€50mg803.00€100mg1,099.00€200mg1,468.00€1mL*10mM (DMSO)236.00€A-3 hydrochloride
CAS:A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formula:C12H14Cl2N2O2SPurity:99.32%Color and Shape:SolidMolecular weight:321.22Ref: TM-T14069
1mg34.00€5mg63.00€10mg90.00€25mg161.00€50mg260.00€100mg416.00€500mg888.00€1mL*10mM (DMSO)95.00€Histone Acetyltransferase Inhibitor II
CAS:Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 μM).with anti-acetylase activityFormula:C20H16Br2O3Purity:97.13%Color and Shape:SolidMolecular weight:464.15Ilginatinib
CAS:Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H20FN7Purity:98.4% - 99.01%Color and Shape:SolidMolecular weight:389.43Ref: TM-T12266
1mg64.00€5mg138.00€10mg187.00€25mg273.00€50mg393.00€100mg562.00€200mg743.00€1mL*10mM (DMSO)133.00€Deferoxamine Mesylate
CAS:Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formula:C26H52N6O11SPurity:94.68% - 99.8%Color and Shape:SolidMolecular weight:656.79Ilginatinib hydrochloride
CAS:Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H21ClFN7Purity:99.55%Color and Shape:SolidMolecular weight:425.89Ref: TM-T12266L2
1mg70.00€5mg150.00€10mg215.00€25mg358.00€50mg517.00€100mg707.00€200mg973.00€1mL*10mM (DMSO)166.00€TRIM24/BRPF1-IN-2
CAS:TRIM24/BRPF1-IN-2 is a TRIM24/BRPF1 dual inhibitor with anticancer activity that inhibits the proliferation of prostate cancer cells.Formula:C20H22N2O4SPurity:98.69% - 99.13%Color and Shape:SoildMolecular weight:386.47FIDAS-5
CAS:FIDAS-5 is an orally active methionine adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM. Cost-effective and quality-assured.Formula:C15H13ClFNPurity:98.3% - 99.17%Color and Shape:SolidMolecular weight:261.72Ref: TM-T11285
1mg59.00€2mg85.00€5mg116.00€10mg187.00€25mg331.00€50mg512.00€100mg740.00€500mg1,415.00€Uzansertib phosphate
CAS:Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase, inhibiting PIM1, PIM2 and PIM3.Formula:C26H29F3N5O7PPurity:99.75% - 99.79%Color and Shape:SolidMolecular weight:611.51Levetiracetam
CAS:Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onsetFormula:C8H14N2O2Purity:99.67% - 99.86%Color and Shape:White Crystalline PowderMolecular weight:170.21MS402
CAS:MS402 is a novel BD1-selective BET BrD inhibitor.Formula:C20H19ClN2O3Purity:99.72%Color and Shape:SolidMolecular weight:370.83Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purity:99.28% - >99.99%Color and Shape:Bright Yellow-Orange Amorphous Solid Crystalline YellowMolecular weight:493.94MAK683
CAS:MAK683 is an inhibitor of embryonic ectoderm development (EED) (IC50s: 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay).Formula:C20H17FN6OPurity:98.25% - 99.92%Color and Shape:SolidMolecular weight:376.39Ref: TM-T15201
1mg52.00€5mg107.00€10mg188.00€25mg411.00€50mg607.00€100mg847.00€500mg1,758.00€1mL*10mM (DMSO)95.00€A-485
CAS:A-485 is a p300/CBP histone acetyltransferase (HAT) inhibitor that inhibits p300 and CBP. A-485 has antitumor effects. Cost effective and quality assured.Formula:C25H24F4N4O5Purity:98.01% - 99.44%Color and Shape:SolidMolecular weight:536.48Ref: TM-T14073
1mg88.00€5mg159.00€10mg273.00€25mg339.00€50mg404.00€100mg698.00€1mL*10mM (DMSO)187.00€Miltefosine
CAS:Miltefosine (HePC), effective oral drug for both visceral and cutaneous leishmaniasis, in clinical trials worldwide.Formula:C21H46NO4PPurity:98% - 99.94%Color and Shape:White To Off-White PowderMolecular weight:407.57Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formula:C5H15N2O3PSPurity:99.59%Color and Shape:White SolidMolecular weight:214.22L-2-Hydroxyglutaric acid disodium
CAS:L-2-Hydroxyglutaric acid disodium may affect epigenetics and contribute to renal cancer, inhibiting Mi-CK (Km 2.52 mM, Ki 11.13 mM).Formula:C5H6Na2O5Purity:99.92%Color and Shape:SolidMolecular weight:192.08ZEN-3694
CAS:ZEN-3694 (ZEN 3694) is a bromo-structural domain extra-terminal inhibitor (BETi) with activity in androgen signaling inhibitor (ASI) resistance models and canFormula:C19H19N5OPurity:98.94% - 99.76%Color and Shape:SolidMolecular weight:333.39Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Formula:C8H6N2S3Purity:98.79% - 99.77%Color and Shape:SolidMolecular weight:226.34ZL0580
CAS:ZL0580 suppresses HIV by blocking Tat activation, halting transcription, and promoting repressive chromatin at the HIV promoter.Formula:C25H23F3N4O4SPurity:99.70%Color and Shape:SolidMolecular weight:532.53NU6140
CAS:NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Formula:C23H30N6O2Purity:98.33%Color and Shape:SolidMolecular weight:422.52Ref: TM-T16359
2mg39.00€5mg60.00€10mg92.00€25mg177.00€50mg285.00€100mg414.00€200mg580.00€1mL*10mM (DMSO)67.00€VTP50469
CAS:VTP50469 is a highly selective and orally active small molecule inhibitor of the Menin-MLL protein-protein interaction.Cost-effective and quality-assured.Formula:C32H47FN6O4SPurity:98.31% - 99.55%Color and Shape:SolidMolecular weight:630.82Ref: TM-T13336
1mg164.00€5mg334.00€10mg401.00€25mg560.00€50mg715.00€100mg964.00€1mL*10mM (DMSO)465.00€Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formula:C6H13NO5·HClPurity:99.77%Color and Shape:White Solid CrystallineMolecular weight:215.63N6-Cyclohexyladenosine
CAS:N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm.Formula:C16H23N5O4Purity:99.92% - 99.98%Color and Shape:SolidMolecular weight:349.38GNE-781
CAS:GNE-781: potent CBP inhibitor (IC50: 0.94 nM), also targets BRET/BRD4(1) (IC50: 6.2/5100 nM).Formula:C27H33F2N7O2Purity:99.25% - 99.64%Color and Shape:SolidMolecular weight:525.59Ref: TM-T15405
1mg138.00€5mg298.00€10mg485.00€25mg808.00€50mg1,093.00€100mg1,483.00€1mL*10mM (DMSO)343.00€SNDX-5613
CAS:Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction.Cost-effective and quality-assured.Formula:C32H47FN6O4SPurity:99.12% - 99.74%Color and Shape:SolidMolecular weight:630.82Ref: TM-T12943
1mg73.00€2mg97.00€5mg160.00€10mg274.00€25mg542.00€50mg778.00€100mg1,074.00€1mL*10mM (DMSO)217.00€Tranylcypromine (2-PCPA) hydrochloride
CAS:Tranylcypromine (2-PCPA) HCl, a MAO inhibitor, treats major, dysthymic, and atypical depression.Formula:C9H11N·HClPurity:99.48% - 99.86%Color and Shape:SolidMolecular weight:169.66Pulrodemstat benzenesulfonate
CAS:Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally inhibitor of lysine specific demethylase-1 (LSD1) with anticancer effect.Formula:C30H29F2N5O5SPurity:97.67%Color and Shape:SolidMolecular weight:609.64Ref: TM-T11882
1mg60.00€2mg86.00€5mg124.00€10mg188.00€25mg329.00€50mg490.00€100mg710.00€1mL*10mM (DMSO)170.00€Bendazol
CAS:Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.
Formula:C14H12N2Purity:98.7% - 99.87%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:208.26A-395
CAS:A-395 blocks PRC2 (EZH2-EED-SUZ12) interactions, strongly inhibiting the complex with an IC50 of 18 nM.
Formula:C26H35FN4O2SPurity:98.43%Color and Shape:SolidMolecular weight:486.65Lin28-let-7a antagonist 1
CAS:Lin28-let-7a antagonist 1, with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction，and shows a clear antagonistic effect against the Lin28-let-7a interaction.Formula:C31H29N5O7Purity:99.44%Color and Shape:SolidMolecular weight:583.59Ref: TM-T11851
1mg96.00€5mg205.00€10mg313.00€25mg562.00€50mg845.00€100mg1,243.00€1mL*10mM (DMSO)266.00€Ilginatinib maleate
CAS:Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2.
Formula:C25H24FN7O4Purity:99.74% - 99.82%Color and Shape:SolidMolecular weight:505.5Delgocitinib
CAS:Delgocitinib is a potent JAK inhibitor (IC50: 2.8-58 nM), treats inflammatory diseases, and is the first topical drug for atopic dermatitis.Formula:C16H18N6OPurity:99.95%Color and Shape:SolidMolecular weight:310.35Ref: TM-T15096
1mg160.00€5mg295.00€10mg462.00€25mg879.00€50mg1,341.00€100mg1,953.00€200mg2,628.00€1mL*10mM (DMSO)330.00€5-Azacytidine
CAS:5-Azacytidine (Ladakamycin) is a cytidine nucleoside analog, a DNA methylation inhibitor with specificity.Formula:C8H12N4O5Purity:98% - 99.79%Color and Shape:Crystals From Methanol Physical Description White Crystalline Powder (Ntp 1992)Molecular weight:244.2Gusacitinib
CAS:Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Formula:C24H28N8O2Purity:98.06% - 99.94%Color and Shape:SolidMolecular weight:460.53Ref: TM-T14331
1mg39.00€5mg84.00€10mg116.00€25mg178.00€50mg333.00€100mg495.00€200mg710.00€1mL*10mM (DMSO)110.00€MAT2A inhibitor 2
CAS:MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A).Formula:C18H24ClN3O3Purity:99.52%Color and Shape:SolidMolecular weight:365.85Golidocitinib
CAS:Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).Formula:C25H31N9O2Purity:98.87% - 99.88%Color and Shape:SolidMolecular weight:489.57Centrinone
CAS:Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).Formula:C26H25F2N7O6S2Purity:98.76%Color and Shape:SolidMolecular weight:633.65JAK2 Inhibitor V
CAS:JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.Formula:C23H24N2OPurity:98.36% - 99.15%Color and Shape:SolidMolecular weight:344.45Ref: TM-T3042
2mg37.00€5mg54.00€10mg80.00€25mg148.00€50mg259.00€100mg477.00€500mg1,063.00€1mL*10mM (DMSO)59.00€MK8722
CAS:MK8722 is an effective and systemic activator of pan-AMPK.Formula:C24H20ClN3O4Purity:98.08% - 99.8800%Color and Shape:SolidMolecular weight:449.89Ref: TM-T16099
1mg34.00€2mg49.00€5mg74.00€10mg113.00€25mg215.00€50mg396.00€100mg585.00€1mL*10mM (DMSO)82.00€MS417
CAS:MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weakFormula:C20H19ClN4O2SPurity:99.87%Color and Shape:SolidMolecular weight:414.91L002
CAS:L002 is a potent inhibitor of acetyltransferase p300 with an IC50 of 1.98 μM, blocking histone and p53 acetylation, and may treat cardiac hypertrophy.Formula:C15H15NO5SPurity:98.59%Color and Shape:SolidMolecular weight:321.35SYP-5
CAS:SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.Formula:C18H16O3SPurity:98.31%Color and Shape:SolidMolecular weight:312.38
