Topoisomerase
Topoisomerases are enzymes that regulate the topology of DNA during processes such as replication, transcription, and chromosome segregation by introducing transient breaks into the DNA strands to relieve torsional stress. Topoisomerase inhibitors interfere with this process, leading to the accumulation of DNA breaks and the induction of cell death, particularly in rapidly dividing cells. These inhibitors are widely used as chemotherapeutic agents in cancer treatment. At CymitQuimica, we offer a broad range of high-quality topoisomerase inhibitors to support your research in DNA replication, cancer therapy, and cell cycle regulation.
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Nalidixic acid
CAS:389-08-2
Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal …
Formula:
C12H12N2O3
Purity:
99.22% - 99.95%
Color and Shape:
Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)
Molecular weight:
232.24
Ref: TM-T0909
| 500mg | 49.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Lomefloxacin
CAS:98079-51-7
Lomefloxacin (SC47111A) is a synthetic broad-spectrum fluoroquinolone with antibacterial activity.
Formula:
C17H19F2N3O3
Purity:
98.59%
Color and Shape:
Off-White To Yellow Crystals
Molecular weight:
351.35
Ref: TM-T1444
| 25mg | 46.00 € | ||
| 100mg | 59.00 € | ||
| 200mg | 74.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Lomefloxacin hydrochloride
CAS:98079-52-8
Lomefloxacin hydrochloride (Okacyn) is a fluoroquinolone that inhibits DNA replication in bacteria, causing cell death.
Formula:
C17H20ClF2N3O3
Purity:
99.43% - 99.75%
Color and Shape:
White Powder
Molecular weight:
387.81
Ref: TM-T1625
| 100mg | 52.00 € | ||
| 500mg | 88.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Epirubicin hydrochloride
CAS:56390-09-1
Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective …
Formula:
C27H30ClNO11
Purity:
98.13% - 99.79%
Color and Shape:
Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
Molecular weight:
579.98
Ref: TM-T0125
| 2mg | 39.00 € | ||
| 5mg | 56.00 € | ||
| 10mg | 88.00 € | ||
| 25mg | 150.00 € | ||
| 50mg | 240.00 € | ||
| 100mg | 324.00 € | ||
| 500mg | 785.00 € | ||
| 1mL*10mM (DMSO) | 73.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Pefloxacin Mesylate Dihydrate
CAS:149676-40-4
Pefloxacin Mesylate Dihydrate (1589 RB) , an antibacterial agent, restrains bacterial DNA replication by inhibiting …
Formula:
C17H20FN3O3·CH4O3S·2H2O
Purity:
99.79%
Color and Shape:
Solid
Molecular weight:
465.49
Ref: TM-T0425L
| 1g | 97.00 € | ||
| 100mg | 34.00 € | ||
| 200mg | 50.00 € | ||
| 500mg | 74.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Gatifloxacin
CAS:112811-59-3
Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.
Formula:
C19H22FN3O4
Purity:
99.50%
Color and Shape:
White Powder
Molecular weight:
375.39
Ref: TM-T1293
| 1g | 52.00 € | ||
| 500mg | 48.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Nalidixic acid sodium salt
CAS:3374-05-8
Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.
Formula:
C12H11N2NaO3
Purity:
99.72% - 99.95%
Color and Shape:
White To Off-White Powder
Molecular weight:
254.22
Ref: TM-T0909L
| 100mg | 42.00 € | ||
| 200mg | 54.00 € | ||
| 500mg | 94.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Berberine chloride
CAS:633-65-8
Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used …
Formula:
C20H18ClNO4
Purity:
98% - 99.93%
Color and Shape:
Yellow Crystalline Powder
Molecular weight:
371.8
Ref: TM-T0461
| 5g | 34.00 € | ||
| 1mL*10mM (DMSO) | 35.00 € |
Estimated delivery in United States, on Monday 14 Apr 2025
Topoisomerase I inhibitor 10
Compound 13, a topoisomerase I inhibitor 10, selectively inhibits leishmanial topoisomerase IB and exhibits antileishmanial …
Purity:
98%
Ref: TM-T80968
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Daun02
CAS:290304-24-4
Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.
Formula:
C41H44N2O20
Purity:
98%
Color and Shape:
Solid
Molecular weight:
884.79
Ref: TM-T15054
| 25mg | 710.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride
Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride, is a topoisomerase I inhibitor that demonstrates effective antibody-drug conjugate (ADC)
Formula:
C26H24ClN3O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
509.94
Ref: TM-T77873
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Apr 2025
DRF-1042 HCl
DRF-1042 HCl is an orally active camptothecin analog with antitumor activity, inhibits DNA topoisomerase I, …
Formula:
C22H21ClN2O6
Purity:
99.212%
Color and Shape:
Liquid
Molecular weight:
444.87
Ref: TM-T15168L
| 1mg | 201.00 € | ||
| 5mg | 497.00 € | ||
| 10mg | 701.00 € | ||
| 25mg | 1,094.00 € | ||
| 50mg | 1,508.00 € | ||
| 100mg | 1,931.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
AuM1Gly
AuM1Gly, a topoisomerase I inhibitor, demonstrates efficacy in inhibiting the proliferation of MDA-MB-231 breast cancer …
Purity:
98%
Ref: TM-T82935
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Nifurpirinol
CAS:13411-16-0
Nifurpirinol (P-7138) is an antimicrobial compound that is acutely toxic to milkfish species.
Formula:
C12H10N2O4
Purity:
99.7%
Color and Shape:
Liquid
Molecular weight:
246.22
Ref: TM-T74065
| 1mg | 57.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 363.00 € | ||
| 50mg | 540.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Voreloxin
CAS:175414-77-4
Voreloxin (SNS-595) is a potent Topoisomerase II inhibitor with broad-spectrum anti-tumor activity. Phase 2.
Formula:
C18H19N5O4S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
401.44
Ref: TM-T6724
| 1mg | 120.00 € | ||
| 5mg | 370.00 € | ||
| 25mg | 1,406.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Ac-Exatecan
CAS:2922852-48-8
Ac-Exatecan, the acetylated form of Exatecan (DX-8951), serves as a prevalent cytotoxic agent in antibody-drug …
Formula:
C26H24FN3O5
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
477.48
Ref: TM-T77901
| 5mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Garenoxacin
CAS:194804-75-6
Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative …
Formula:
C23H20F2N2O4
Purity:
98%
Color and Shape:
Solid
Molecular weight:
426.41
Ref: TM-T7179
| 5mg | 261.00 € | ||
| 10mg | 393.00 € | ||
| 25mg | 837.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
AuM1Phe
AuM1Phe, an N-heterocyclic carbene (NHC) metal complex, inhibits both human topoisomerase I activity and actin …
Purity:
98%
Ref: TM-T82934
| 5mg | To inquire | ||
| 50mg | To inquire |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Aclacinomycin A
CAS:57576-44-0
Aclacinomycin A has a wide range of applications in life science related research.
Formula:
C42H53NO15
Purity:
99.43%
Color and Shape:
Solid
Molecular weight:
811.87
Ref: TM-T21502
| 1mg | 284.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
Chimmitecan
CAS:185425-25-6
Chimmitecan ((S)-9-Allyl-10-hydroxycamptothecin) is a potent inhibitor of topoisomerase I and displays outstanding activity in vitro …
Formula:
C23H20N2O5
Purity:
98.5%
Color and Shape:
Soild
Molecular weight:
404.42
Ref: TM-T60123
| 1mg | 94.00 € | ||
| 5mg | 207.00 € | ||
| 10mg | 293.00 € | ||
| 25mg | 452.00 € | ||
| 50mg | 645.00 € | ||
| 100mg | 889.00 € | ||
| 200mg | 1,198.00 € | ||
| 1mL*10mM (DMSO) | 226.00 € |
Estimated delivery in United States, on Tuesday 15 Apr 2025
