Topoisomerase
Topoisomerases are enzymes that regulate the topology of DNA during processes such as replication, transcription, and chromosome segregation by introducing transient breaks into the DNA strands to relieve torsional stress. Topoisomerase inhibitors interfere with this process, leading to the accumulation of DNA breaks and the induction of cell death, particularly in rapidly dividing cells. These inhibitors are widely used as chemotherapeutic agents in cancer treatment. At CymitQuimica, we offer a broad range of high-quality topoisomerase inhibitors to support your research in DNA replication, cancer therapy, and cell cycle regulation.
Found 129 products of "Topoisomerase"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formula:C27H29NO11·HClPurity:98% - 99.52%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.99Teniposide
CAS:Teniposide (VM26), a semisynthetic derivative of podophyllotoxin with antitumor activity, inhibits DNA synthesis by forming a complex with topoisomerase II andFormula:C32H32O13SPurity:97.7% - 99.45%Color and Shape:White Or Off-White Crystalline PowderMolecular weight:656.65Moxifloxacin hydrochloride
CAS:Moxifloxacin hydrochloride (BAY12-8039 HCl) is a fourth generation fluoroquinolone with expanded activity against gram-positive bacteria and atypical pathogens.Formula:C21H25ClFN3O4Purity:99.91% - >99.99%Color and Shape:SolidMolecular weight:437.89Enoxacin hydrate
CAS:Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.Formula:C15H17FN4O3H2OPurity:99.50%Color and Shape:SolidMolecular weight:347.34Nalidixic acid
CAS:Nalidixic acid (NSC-82174), a synthetic antimicrobial, targets bacterial DNA gyrase A, with a narrow bactericidal range.Formula:C12H12N2O3Purity:99.9% - 99.95%Color and Shape:Pale Buff Crystalline Powder Physical Description Cream-Colored Powder (Ntp 1992)Molecular weight:232.24Lurtotecan
CAS:Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.
Formula:C28H30N4O6Purity:99.18%Color and Shape:SoildMolecular weight:518.56Epirubicin hydrochloride
CAS:Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.Formula:C27H30ClNO11Purity:98.13% - 99.79%Color and Shape:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Molecular weight:579.98Ref: TM-T0125
2mg37.00€5mg52.00€10mg84.00€25mg142.00€50mg226.00€100mg308.00€500mg745.00€1mL*10mM (DMSO)70.00€Nalidixic acid sodium salt
CAS:Nalidixic acid sodium salt (Baktogram) is an antimicrobial agent with a limited bacteriocidal spectrum.Formula:C12H11N2NaO3Purity:99.72% - 99.95%Color and Shape:White To Off-White PowderMolecular weight:254.22Daunorubicin hydrochloride
CAS:Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFormula:C27H29NO10·HClPurity:96.21% - 99.53%Color and Shape:Cancer DrugMolecular weight:563.99Ref: TM-T1511
5mg34.00€10mg52.00€25mg87.00€50mg113.00€100mg177.00€200mg281.00€500mg442.00€1mL*10mM (DMSO)59.00€Berberine chloride
CAS:Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.Formula:C20H18ClNO4Purity:99.47% - 99.93%Color and Shape:Yellow Crystalline PowderMolecular weight:371.80Mitoxantrone dihydrochloride
CAS:Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formula:C22H30Cl2N4O6Purity:97.05% - >99.99%Color and Shape:Blue-Black Solid From Water Ethanol SolidMolecular weight:517.4Ciprofloxacin monohydrochloride
CAS:Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.Formula:C17H18FN3O3·HClPurity:99.5% - 99.73%Color and Shape:White Or Light Yellow Crystalline PowderMolecular weight:367.80Ciprofloxacin
CAS:Ciprofloxacin (Bay-09867) mainly targets bacterial DNA Gyrase (IC50=0.22-0.31 µM) and topoisomerase IV (IC50=0.3-1.9 µM). antibiotic. High-Quality, Low-Cost!Formula:C17H18FN3O3Purity:98.77% - 99.91%Color and Shape:White PowderMolecular weight:331.34Topotecan hydrochloride
CAS:Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.Formula:C23H24ClN3O5Purity:97.88% - 99.41%Color and Shape:White Crystalline SolidMolecular weight:457.92Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Formula:C33H45ClN4O9Purity:98.22% - >99.99%Color and Shape:Pale Yellow To Yellow Crystalline PowderMolecular weight:677.18Oxaquin TEA
Oxaquin TEA (MCB-3837 TEA), a precursor compound to MCB3681, is a DNA topoisomerase inhibitor that can be used to study Clostridium difficile infections and
Formula:C37H48F2N5O11PPurity:99.79%Color and Shape:SolidMolecular weight:807.77Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Formula:C33H39ClN4O6Purity:98% - 99.94%Color and Shape:Yellow Crystalline PowderMolecular weight:623.14Ref: TM-T0486L
10mg34.00€25mg49.00€50mg65.00€100mg89.00€200mg129.00€500mg254.00€1mL*10mM (DMSO)71.00€Gatifloxacin
CAS:Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.Formula:C19H22FN3O4Purity:99.50% - 99.85%Color and Shape:White PowderMolecular weight:375.39Hycanthone
CAS:Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.Formula:C20H24N2O2SPurity:98.78%Color and Shape:Yellow-Orange Powder (Ntp 1992)Molecular weight:356.48Levofloxacin hydrate
CAS:Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Formula:C18H20FN3O4H2OPurity:98.26%Color and Shape:Pale Yellow SolidMolecular weight:370.38
