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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3035 products of "Immunology and Inflammation"

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  • Ginger extract

    CAS:
    <p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>
    Color and Shape:Solid
  • CNTO4088


    <p>CNTO4088 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It holds potential for research in autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>
    Color and Shape:Odour Liquid
  • Bivalirudin TFA

    CAS:
    <p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>
    Formula:C98H138N24O33·C2HF3O2
    Color and Shape:Solid
    Molecular weight:2294.34
  • Ieramilimab


    <p>Ieramilimab (LAG525) is a humanized antibody targeting LAG-3 with potential anticancer activity for the study of malignant tumors.</p>
    Purity:96.4% (SDS-PAGE); 97.8% (SEC-HPLC) - 96.4% (SDS-PAGE); 97.8% (SEC-HPLC)
    Color and Shape:Odour Liquid
  • NLRP3-IN-48


    <p>NLRP3-IN-48 is an inhibitor of NLRP3. It suppresses the activation of the NLRP3 inflammasome by targeting the NLRP3 protein, thereby interfering with the assembly of the NLRP3 inflammasome. Additionally, NLRP3-IN-48 exhibits anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>
    Color and Shape:Odour Solid
  • Mosnodenvir

    CAS:
    <p>Mosnodenvir is a pan-DENV inhibitor effective against all four serotypes of dengue viruses, with the advantage of being highly potent and orally bioavailable, and blocks viral replication by inhibiting the formation of the complex between NS3 and NS4B.</p>
    Formula:C26H22ClF3N2O6S
    Purity:99.72%
    Color and Shape:Soild
    Molecular weight:582.98
  • BMS-986179


    <p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>
    Color and Shape:Odour Liquid
  • NLRP3-IN-14

    CAS:
    <p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>
    Formula:C27H28N2O4
    Color and Shape:Solid
    Molecular weight:444.52
  • PMX 205 Trifluoroacetate


    <p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>
    Formula:C47H63F3N10O8
    Color and Shape:Solid
    Molecular weight:953.06
  • Moxilubant HCl

    CAS:
    <p>Moxilubant HCl: small molecule LTB4R antagonist for immune, skin, musculoskeletal disorders, and research in psoriasis, arthritis.</p>
    Formula:C26H38ClN3O4
    Purity:99.94%
    Color and Shape:Soild
    Molecular weight:492.05
  • C6 L-threo Ceramide (d18:1/6:0)

    CAS:
    <p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>
    Formula:C24H47NO3
    Color and Shape:Solid
    Molecular weight:397.63
  • ZL-1102


    <p>ZL-1102 is a humanized monoclonal antibody inhibitor targeting interleukin-17A (IL-17A). SCH-900117 is being investigated for its potential use in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis.</p>
    Color and Shape:Odour Liquid
  • Rucosopasem manganese

    CAS:
    <p>Rucosopasem manganese (GC4711), a selective SOD mimetic, converts superoxide to peroxide for cancer research.</p>
    Formula:C27H45MnN5O4
    Color and Shape:Solid
    Molecular weight:558.626
  • Phthalazine

    CAS:
    <p>Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C8H6N2
    Color and Shape:Yellow Solid
    Molecular weight:130.14
  • Butan-1-amine hydrochloride

    CAS:
    <p>1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).</p>
    Formula:C4H12ClN
    Color and Shape:Solid
    Molecular weight:109.6
  • AMY-101

    CAS:
    <p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>
    Formula:C83H117N23O18S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1789.11
  • 1-Ethoxycarbonyl-β-carboline

    CAS:
    <p>1-Ethoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN7072 and the CAS number is 72755-19-2.</p>
    Formula:C28H23N4O4
    Color and Shape:Solid
    Molecular weight:479.516
  • Tetrachlorohydroquinone

    CAS:
    <p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>
    Formula:C6H2Cl4O2
    Color and Shape:Solid
    Molecular weight:247.89
  • iE-DAP dihydrochloride


    <p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>
    Formula:C12H23Cl2N3O7
    Color and Shape:Solid
    Molecular weight:391.09131
  • Allyl methyl trisulfide

    CAS:
    <p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>
    Formula:C4H8S3
    Color and Shape:Solid
    Molecular weight:152.3
  • CAY10614

    CAS:
    <p>CAY10614 is a TLR4 antagonist.</p>
    Formula:C42H78INO2
    Color and Shape:Solid
    Molecular weight:755.995
  • Sirtuin modulator 2

    CAS:
    <p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>
    Formula:C19H15N3O2S
    Purity:99.67%
    Color and Shape:Solid
    Molecular weight:349.41
  • STING modulator-5

    CAS:
    <p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>
    Formula:C43H45F4N11O5
    Color and Shape:Solid
    Molecular weight:871.88
  • Salicortin

    CAS:
    <p>Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.</p>
    Formula:C20H24O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:424.40
  • Polyinosinic acid

    CAS:
    <p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>
    Formula:(C10H13N4O8P)x
    Color and Shape:Solid
  • STING agonist-17

    CAS:
    <p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>
    Formula:C43H53N13O8
    Color and Shape:Solid
    Molecular weight:879.96
  • QX-005N


    <p>QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.</p>
    Color and Shape:Odour Liquid
  • KYN-101

    CAS:
    <p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>
    Formula:C22H19FN6
    Purity:98.35%
    Color and Shape:Solid
    Molecular weight:386.43
  • Isoxaben

    CAS:
    <p>Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into</p>
    Formula:C18H24N2O4
    Purity:98.84%
    Color and Shape:Solid
    Molecular weight:332.39
  • ATWLPPR Peptide TFA


    <p>ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.</p>
    Formula:C42H62F3N11O11
    Purity:98%
    Color and Shape:Solid
    Molecular weight:954
  • cGAMP disodium

    CAS:
    <p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>
    Formula:C20H24N10O13P2·2Na
    Color and Shape:Soild
    Molecular weight:720.39
  • FM101


    <p>FM101 is a humanized monoclonal anti-IL6 antibody, suitable for use in asthma-related research.</p>
    Color and Shape:Odour Liquid
  • NLRP3-IN-49


    <p>NLRP3-IN-49 (compound Z48) is a potent and specific inhibitor of NLRP3, displaying IC50 values of 0.26 μM in THP-1 cells and 0.21 μM in mouse bone marrow-derived macrophages. It directly binds to the NLRP3 protein with a dissociation constant (Kd) of 1.05 μM, effectively preventing the assembly and activation of the NLRP3 inflammasome, thereby exhibiting anti-inflammatory properties. NLRP3-IN-49 is utilized in the research of inflammatory bowel disease.</p>
    Color and Shape:Odour Solid
  • Phytoene desaturase-IN-1

    CAS:
    <p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>
    Formula:C18H13ClF3N3O2S
    Color and Shape:Solid
    Molecular weight:427.83
  • Valeriandoid F

    CAS:
    <p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>
    Formula:C23H34O9
    Color and Shape:Solid
    Molecular weight:454.516
  • Timosaponin E2

    CAS:
    <p>Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].</p>
    Formula:C46H78O20
    Color and Shape:Solid
    Molecular weight:951.1
  • Mesalamine impurity P

    CAS:
    <p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>
    Formula:C13H11NO6S
    Color and Shape:Solid
    Molecular weight:309.30
  • TLR4 agonist-1 TEA


    <p>TLR4 agonist-1 (TEA, compound 17a) is a potent activator of Toll-like Receptor 4 (TLR4) and prompts the production of MIP-1β in RAW 264.7 and MM6 cells [1].</p>
    Color and Shape:Odour Solid
  • MCI


    <p>MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation</p>
    Formula:C45H52ClN7O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:934.39
  • CAY10657

    CAS:
    <p>CAY10657 has a wide range of applications in life science related research.</p>
    Formula:C17H20N4O3S
    Color and Shape:Solid
    Molecular weight:360.43
  • GSK1795091

    CAS:
    <p>GSK1795091, a synthetic TLR4 agonist, boosts immunity and shows antitumor effects, enhancing flu vaccine response.</p>
    Formula:C81H157N2O16P
    Color and Shape:Solid
    Molecular weight:1446.119
  • COX-2/15-LOX-IN-2


    <p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>
    Formula:C27H26N6OS2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:514.66
  • Feeblin

    CAS:
    <p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>
    Formula:C27H33N3O2
    Purity:99.58% - 99.88%
    Color and Shape:Soild
    Molecular weight:431.57
  • LL-37 GKE acetate


    <p>LL-37 GKE acetate, a peptide and active structural domain of LL-37, inhibits lps-induced vascular nitric oxide production,less toxic,antimicrobial,sepsis.</p>
    Formula:C121H206N38O30
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:2673.17
  • Gliotoxin

    CAS:
    <p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>
    Formula:C13H14N2O4S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:326.39
  • Gp100 (25-33), human

    CAS:
    <p>Gp100 (25-33), human: 9-AA melanoma antigen fragment, H-2Db restricted, T-cell recognized, targets B16 melanoma.</p>
    Formula:C52H82N16O14
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1155.31
  • PROTAC STING Degrader-1

    CAS:
    <p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>
    Formula:C34H33N7O10
    Color and Shape:Solid
    Molecular weight:699.67
  • NF-κΒ activator 1

    CAS:
    <p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>
    Formula:C16H11FN2O2S
    Purity:99.58%
    Color and Shape:Solid
    Molecular weight:314.33
  • Balekafusp alfa

    CAS:
    <p>Balekafusp alfa is a human IgG1κ antibody targeting IL-2, known for its antitumor properties.</p>
    Color and Shape:Liquid
  • 3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide

    CAS:
    <p>3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).</p>
    Formula:C28H24ClN3O6
    Purity:99.9%
    Color and Shape:Solid
    Molecular weight:533.96
  • 1-Hydroxy-ibuprofen

    CAS:
    <p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>
    Formula:C13H18O3
    Color and Shape:Solid
    Molecular weight:222.2802
  • Anti-IL11RA Antibody (X209)


    <p>Anti-IL11RA Antibody (X209) is a human-derived IgG4, κ type antibody inhibitor targeting human IL-11RA.</p>
    Color and Shape:Odour Liquid
  • Mifamurtide sodium

    CAS:
    <p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>
    Formula:C59H108N6NaO19P
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1259.48
  • NF-κB-IN-9


    <p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>
    Formula:C62H50N4O4S
    Color and Shape:Solid
    Molecular weight:947.15
  • [12]-Dehydrogingerdione

    CAS:
    <p>[12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity.Cost-effective and quality-assured.</p>
    Formula:C23H34O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:374.51
  • Aminopicoline

    CAS:
    <p>Compound Fr16695, with CAS No. 695-34-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16695 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formula:C6H8N2
    Color and Shape:White To Pale Yellow Solid Flakes
    Molecular weight:108.14
  • Cyclic-di-GMP disodium

    CAS:
    <p>Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria.Cost-effective and quality-assured.</p>
    Formula:C20H22N10Na2O14P2
    Purity:98.98% - 99.93%
    Color and Shape:Solid
    Molecular weight:734.38
  • E7766 disodium

    CAS:
    <p>E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.</p>
    Formula:C24H26F2N10Na2O8P2S2
    Color and Shape:Solid
    Molecular weight:792.58
  • HNGF6A

    CAS:
    <p>increases glucose stimulated insulin secretion and glucose metabolism</p>
    Formula:C112H198N34O31S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:2581.11
  • STING-IN-13


    <p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>
    Color and Shape:Odour Solid
  • PSMA-IN-3


    <p>PSMA-IN-3 (compound 17) is a novel, high-affinity inhibitor of Prostate-Specific Membrane Antigen (PSMA) with an inhibitory concentration (IC50) of 13 nM,</p>
    Formula:C43H50FN7O15
    Color and Shape:Solid
    Molecular weight:923.89
  • CFT7455

    CAS:
    <p>CFT7455: orally active anti-cancer drug, targets cereblon E3 ligase (Kd 0.9 nM), degrades IKZF1/Ikaros, IKZF3/Aiolos.</p>
    Formula:C28H27N3O4
    Purity:97.93%
    Color and Shape:Solid
    Molecular weight:469.53
  • JH-FK-08


    <p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>
    Formula:C45H73N3O13
    Color and Shape:Solid
    Molecular weight:864.073
  • Obinutuzumab

    CAS:
    <p>Obinutuzumab (Obinutuzumab/afutuzumab) GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.</p>
    Purity:98.00% - 98.9% (SDS-PAGE); 99.4% (SEC-HPLC)
    Color and Shape:Liquid
    Molecular weight:144.6 kDa
  • NLRP3-IN-74


    <p>NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 of 2.7 μM. It significantly reduces IL-1β release by approximately 90% without affecting TNFα release. NLRP3-IN-74 is applicable in research on diseases such as atherosclerosis and Parkinson's disease.</p>
    Color and Shape:Odour Solid
  • Eftilagimod alfa

    CAS:
    <p>Eftilagimod alfa (IMP321), a recombinant LAG-3Ig fusion protein, binds to MHC class II and mediates the activation of antigen-presenting cells (APCs), which in</p>
    Color and Shape:Liquid
  • LY2409881

    CAS:
    <p>LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.</p>
    Formula:C24H29ClN6OS
    Color and Shape:Solid
    Molecular weight:485.05
  • TLR8 agonist 8

    CAS:
    <p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>
    Formula:C53H63N11O10
    Color and Shape:Solid
    Molecular weight:1014.14
  • HPK1-IN-58


    <p>HPK1-IN-58 is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). It enhances IL-2 secretion, thereby reversing PGE2-induced immunosuppression. HPK1-IN-58 is applicable for research in antitumor immunity.</p>
    Formula:C26H30N8O
    Color and Shape:Solid
    Molecular weight:470.25426
  • Cryogenine

    CAS:
    <p>Cryogenine, from H. salicifolia, is an anti-inflammatory alkaloid, blocks prostaglandin synthetase, and alleviates rat arthritis.</p>
    Formula:C26H29NO5
    Color and Shape:Solid
    Molecular weight:435.52
  • Antidesmone

    CAS:
    <p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>
    Formula:C19H29NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:319.44
  • Sericin


    <p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>
    Color and Shape:Odour Solid
  • FGT-4


    <p>FGT-4 is a chimeric molecule targeting folate receptor β (FR-β) and functions as a TLR7 agonist. It enhances the secretion of iNOS and the pro-inflammatory cytokine IL-6 associated with M1 macrophages and promotes the proliferation of cytotoxic CD8+ T cells. FGT-4 demonstrates antitumor activity in the 4T1 breast cancer mouse model and is applicable for cancer immunotherapy research.</p>
    Formula:C50H57N11O9S2
    Color and Shape:Solid
    Molecular weight:1019.37821
  • c-di-AMP disodium

    CAS:
    <p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>
    Formula:C20H22N10Na2O12P2
    Color and Shape:Solid
    Molecular weight:702.38
  • TLR7 agonist 17

    CAS:
    <p>TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].</p>
    Formula:C25H37N7O3
    Color and Shape:Solid
    Molecular weight:483.61
  • ODN D-SL03

    CAS:
    <p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells &amp; monocytes, and can inhibit tumor growth.</p>
    Color and Shape:Solid
    Molecular weight:9345
  • Siegesbeckialide I


    <p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>
    Formula:C20H28O6
    Color and Shape:Solid
    Molecular weight:364.43
  • 7-O-Methylaloeasinol

    CAS:
    <p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>
    Formula:C20H26O9
    Color and Shape:Solid
    Molecular weight:410.419
  • His-Pro

    CAS:
    <p>His-Pro is a dipeptide consisting of histidyl and proline.</p>
    Formula:C11H16N4O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:252.27
  • Ketoprofen lysine salt

    CAS:
    <p>Ketoprofen lysine salt is a lysine salt of ketoprofen, a Non-Steroidal Anti-Inflammatory Drug</p>
    Formula:C22H28N2O5
    Color and Shape:Solid
    Molecular weight:400.48
  • 3′-Hydroxy-4′-O-methylglabridin

    CAS:
    <p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>
    Formula:C21H22O5
    Color and Shape:Solid
    Molecular weight:354.4
  • Helenalin

    CAS:
    <p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>
    Formula:C15H18O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:262.3
  • 7-Deoxy-trans-dihydronarciclasine

    CAS:
    <p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>
    Formula:C14H15NO6
    Color and Shape:Solid
    Molecular weight:293.27
  • Glutathione ethyl ester acetate


    <p>Glutathione ethyl ester acetate is an antioxidant and cell-permeable Glutathione (GSH) donor that restore oxidative stress and TGase up-regulation.</p>
    Formula:C14H25N3O8S
    Purity:97.49%
    Color and Shape:Solid
    Molecular weight:395.43
  • Romurtide

    CAS:
    <p>Romurtide is a synthetic muramyl dipeptide analog and can be used for the prophylaxis of leukocytopenia during radiation therapy.</p>
    Formula:C43H78N6O13
    Purity:98%
    Color and Shape:Solid
    Molecular weight:887.126
  • Bavunalimab

    CAS:
    <p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>
    Color and Shape:Liquid
  • FM-303


    <p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>
    Color and Shape:Odour Liquid
  • G3-C12

    CAS:
    <p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>
    Formula:C74H115N23O23S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1758.99
  • Prezalumab

    CAS:
    <p>Prezalumab (AMG 557) is a human IgG2 monoclonal antibody against ICOSL and BAFF.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:145.42 kDa
  • STING agonist-8 dihydrochloride


    <p>STING Agonist-8 Dihydrochloride (Compound 5-AB) is a highly effective STING agonist, exhibiting an EC50 value of 27 nM in THP1-Dual KI-hSTING-R232 cells.</p>
    Formula:C41H48Cl2N14O4
    Color and Shape:Solid
    Molecular weight:871.82
  • N-decanoyl-L-Homoserine lactone

    CAS:
    <p>C10-HSL, an AHL from Pseudomonas cremoris ND07, stunts Arabidopsis roots by raising Ca2+, ROS, MPK6 activity, and NO levels.</p>
    Formula:C14H25NO3
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:255.35
  • Ladanetin-6-O-β-D-glucopyranoside

    CAS:
    <p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>
    Formula:C22H22O11
    Color and Shape:Solid
    Molecular weight:462.4
  • BRD5075


    <p>BRD5075 is an effective activator of GPR65, stimulating the production of cAMP in a GPR65-dependent manner. Additionally, it reduces the gene expression of IL-1, IL-2, TNF, and chemokines. BRD5075 holds potential for researching multiple sclerosis and inflammatory bowel disease (IBD).</p>
    Color and Shape:Odour Solid
  • CRX 527

    CAS:
    <p>CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.</p>
    Formula:C81H151N2O19P
    Color and Shape:Solid
    Molecular weight:1488.04
  • SIN 14


    <p>SIN 14 is an HO-1 activator that targets and activates HO-1 through an allosteric mechanism. Additionally, SIN 14 can induce the polarization of macrophages from the M1 phenotype to the M2 phenotype.</p>
    Formula:C20H22ClNO4
    Color and Shape:Solid
    Molecular weight:375.12374
  • Pam2CSK4

    CAS:
    <p>TLR2/6 agonist; boosts TNF-α in human cells &amp; mouse B cell growth/activation.</p>
    Formula:C65H126N10O12S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1271.83
  • MethADP sodium salt

    CAS:
    <p>MethADP is a specific CD73 inhibitor.</p>
    Formula:C11H17N5NaO9P2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:448.22
  • KD014


    <p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>
    Color and Shape:Odour Liquid
  • Reltecimod

    CAS:
    <p>Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.</p>
    Formula:C46H72N10O15S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1037.19
  • cGAMP diammonium


    <p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>
    Formula:C20H30N12O13P2
    Color and Shape:Solid
    Molecular weight:708.47