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Immunology and Inflammation

Immunology and Inflammation

Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.

Subcategories of "Immunology and Inflammation"

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Found 3034 products of "Immunology and Inflammation"

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  • Edasalonexent

    CAS:
    <p>Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.</p>
    Formula:C31H42N2O3
    Purity:99.13% - >99.99%
    Color and Shape:Solid
    Molecular weight:490.68
  • Emlenoflast sodium

    CAS:
    <p>Emlenoflast sodium (MCC7840 sodium), a sulfonylurea, is a selective NLRP3 inflammasome inhibitor with an IC50 value of less than 100 nM for NLRP3 inflammasome,</p>
    Formula:C19H24N4NaO3S
    Color and Shape:Solid
    Molecular weight:411.47
  • MK-0703

    CAS:
    <p>MK-0703 is a selective cyclooxygenase-2 inhibitor.</p>
    Formula:C17H22O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:338.42
  • Bay 65-1942 hydrochloride

    CAS:
    <p>Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.</p>
    Formula:C22H26ClN3O4
    Color and Shape:Solid
    Molecular weight:431.91
  • Insulin levels modulator

    CAS:
    <p>Insulin level regulators can be used to treat diabetes.</p>
    Formula:C21H23N7OS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:421.52
  • COX-2/5-LOX-IN-1

    CAS:
    <p>COX-2/5-LOX-IN-1, a benzothiophen-2-yl pyrazole, inhibits COX-2 &amp; 5-LOX with IC50: COX-1 (12.13μM), COX-2 (0.4μM), 5-LOX (4.96μM). Better than Celecoxib.</p>
    Formula:C14H10ClN3O4S2
    Color and Shape:Solid
    Molecular weight:383.83
  • IKKβ-IN-1

    CAS:
    <p>IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM).</p>
    Formula:C31H30N4O4S
    Color and Shape:Solid
    Molecular weight:554.66
  • MIND4-17

    CAS:
    <p>MIND4-17 activates NRF2 by binding Keap1 C151, blocking Keap1-Nrf2, stabilizes Nrf2, and promotes its nuclear entry, with strong antioxidant effects.</p>
    Formula:C20H15N5O3S
    Color and Shape:Solid
    Molecular weight:405.43
  • IRAK4-IN-21

    CAS:
    <p>IRAK4-IN-21: Oral IRAK4 inhibitor, IC50: IRAK4 5 nM, TAK1 56 nM; curbs IL-23, aids autoimmune research.</p>
    Formula:C28H28FN7O2
    Color and Shape:Solid
    Molecular weight:513.57
  • MitoB

    CAS:
    <p>MitoB is a novel exon of mitochondrial hydrogen peroxide.</p>
    Formula:C25H23BBrO2P
    Color and Shape:Solid
    Molecular weight:477.14
  • Heterophdoid A

    CAS:
    <p>Heterophdoid A is an anti-inflammatory agent that inhibits NO production in BV-2 cells (IC50: 5.93 μM).</p>
    Formula:C26H42O10
    Color and Shape:Solid
    Molecular weight:514.61
  • Ruzotolimod

    CAS:
    <p>Ruzotolimod, an agonist of TLR7, exhibits promising potential for investigating HBV, COVID-19, and SARS-CoV-2 infections (WO2021130195A1)[1].</p>
    Formula:C14H18N4O5S
    Color and Shape:Solid
    Molecular weight:354.38
  • COX-2/15-LOX-IN-1

    CAS:
    <p>COX-2/15-LOX-IN-1 is a dual inhibitor for COX-2/15-LOX with anti-inflammatory properties (IC50: COX-1 10.65μM, COX-2 0.075μM, 15-LOX 2.98μM).</p>
    Formula:C21H21N7S3
    Color and Shape:Solid
    Molecular weight:467.63
  • Clopirac

    CAS:
    <p>Clopirac is a potent and orally active prostaglandin synthetase inhibitor that is an anti-inflammatory agent [1].</p>
    Formula:C14H14ClNO2
    Color and Shape:Solid
    Molecular weight:263.72
  • NF-κB-IN-2

    CAS:
    <p>NF-κB-IN-2 inhibits canonical NF-κB signaling induced by TNF-α in PC-3 cells.</p>
    Formula:C15H18O3
    Color and Shape:Solid
    Molecular weight:246.3
  • Gue1654

    CAS:
    <p>Gue1654 is an OXE-R inhibitor and cardiomyocyte apoptosis.Gue1654 can be used for the study of cardiovascular diseases.</p>
    Formula:C23H17N3OS3
    Purity:98.02% - 98.04%
    Color and Shape:Solid
    Molecular weight:447.6
  • AVE3085

    CAS:
    <p>AVE3085 is an enhancer of endothelial nitric oxide synthase that restores endothelial function and lowers blood pressure in spontaneously hypertensive rats.</p>
    Formula:C17H13F2NO3
    Purity:99.87%
    Color and Shape:Solid
    Molecular weight:317.29
  • Methyl aminolevulinate

    CAS:
    <p>Methyl aminolevulinate, a prodrug for protoporphyrin IX, sensitizes in PDT.</p>
    Formula:C6H11NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:145.16
  • Dihydrolipoic acid

    CAS:
    <p>Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.</p>
    Formula:C8H16O2S2
    Purity:97.51%
    Color and Shape:Yellow To Orange Liquid
    Molecular weight:208.34
  • TPO agonist 1

    CAS:
    <p>TPO agonist 1 is a thrombopoietin agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.</p>
    Formula:C25H22N8O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:466.49
  • (R)-MLT-985

    CAS:
    <p>(R)-MLT-985 (compound 11) is a MALT1 protease inhibitor with IC50 of 3 nM, also blocking IL-2 in Jurkat cells and ABC-DLBCL cell growth.</p>
    Formula:C17H15Cl2N9O2
    Color and Shape:Solid
    Molecular weight:448.27
  • COX-2-IN-18

    CAS:
    <p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>
    Formula:C18H19N3O3S2
    Color and Shape:Solid
    Molecular weight:389.49
  • MD13


    <p>MD13 is a macrophage migration inhibitor (MIF) oriented PROTAC (Ki value: 71 nM). MD13 can be used to study cancer.</p>
    Color and Shape:Liquid
  • SMA-12b

    CAS:
    <p>SMA-12b is an analog of the immunomodulatory parasite product ES-62 that has immunomodulatory activity and can be used in the study of rheumatoid arthritis.</p>
    Formula:C13H22INO2S
    Purity:98.52% - 99.16%
    Color and Shape:Solid
    Molecular weight:383.29
  • Sulfo-ara-F-NMN

    CAS:
    <p>Sulfo-ara-F-NMN: cell-permeable, NMN analogue, activates SARM1, inhibits CD38 (IC50 ~10μM), induces cADPR, NAD loss, non-apoptotic death.</p>
    Formula:C11H14FN2O6PS
    Purity:98%
    Color and Shape:Solid
    Molecular weight:352.28
  • Mercaptoethylguanidine (MEG) (dihydrobromide)

    CAS:
    <p>MEG dihydrobromide inhibits inducible nitric oxide synthase and scavenges peroxynitrite, potentially aiding in inflammatory bowel disease studies.</p>
    Formula:C3H11Br2N3S
    Color and Shape:Solid
    Molecular weight:281.01
  • AL-8417

    CAS:
    <p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>
    Formula:C29H34O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.58
  • IRAK inhibitor 4

    CAS:
    <p>IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor.</p>
    Formula:C33H35F3N6O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:620.66
  • L-NIL hydrochloride

    CAS:
    <p>selective inhibitor of inducible nitric oxide synthase</p>
    Formula:C8H18ClN3O2
    Purity:98%
    Color and Shape:White To Off-White Solid
    Molecular weight:223.7
  • IRAK4-IN-16

    CAS:
    <p>IRAK4-IN-16 inhibits IRAK4 at 2.5nM; cytotoxic to OCI-LY10, TMD8, Ramos, HT cells with IC50s of 0.2, 0.2, 0.6, 2.7μM.</p>
    Formula:C17H20F2N8O
    Color and Shape:Solid
    Molecular weight:390.39
  • CD73-IN-8

    CAS:
    <p>CD73-IN-8 blocks CD73, hindering adenosine production that supports tumor growth, flagged as compound 57 in WO2022052886A1.</p>
    Formula:C17H13ClN4O2
    Color and Shape:Solid
    Molecular weight:340.76
  • STING Agonist 12b

    CAS:
    <p>STING agonist 12b activates human/mouse STING, binds with Kd 26.4 μM, prompts interferon, and induces TNF-a, IL-6, IP-10, IL-1b in THP-1 cells.</p>
    Formula:C16H15NO2
    Color and Shape:Solid
    Molecular weight:253.3
  • GSK319347A

    CAS:
    <p>GSK319347A is a dual inhibitor of TBK1 and IKKε that inhibits IKK2 and can be used to study bladder and lung adenocarcinomas.</p>
    Formula:C22H19N3O5S2
    Purity:98.42%
    Color and Shape:Solid
    Molecular weight:469.53
  • Cyclic-di-GMP

    CAS:
    <p>Cyclic-di-GMP is a STING agonist and ubiquitous second messenger, which regulates the formation, motility and virulence of biofilms in various bacterial species</p>
    Formula:C20H24N10O14P2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:690.41
  • AMT hydrochloride

    CAS:
    <p>AMT hydrochloride is an iNOS inhibitor.</p>
    Formula:C5H11ClN2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:166.67
  • Mivotilate

    CAS:
    <p>Mivotilate, a potent, non-toxic aryl hydrocarbon receptor (AhR) activator, functions as a hepatoprotective agent.</p>
    Formula:C12H14N2O3S3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:330.45
  • AR-C102222 hydrochloride

    CAS:
    <p>AR-C102222 hydrochloride: oral iNOS inhibitor, selective, IC50=37 nM, with anti-inflammatory and pain relief effects.</p>
    Formula:C19H17ClF2N6O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:418.83
  • NED-3238

    CAS:
    <p>NED-3238 is a highly potent inhibitor of arginase I and II (IC50 of 1.3 nM and 8.1 nM, respectively).</p>
    Formula:C17H28BN3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:349.23
  • Xanthine oxidase-IN-6


    <p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>
    Formula:C29H34N2O15
    Color and Shape:Solid
    Molecular weight:650.58
  • MLT-747

    CAS:
    <p>MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).</p>
    Formula:C20H21Cl2N7O3
    Color and Shape:Solid
    Molecular weight:478.33
  • COX-2-IN-11

    CAS:
    <p>COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].</p>
    Formula:C12H12OS3
    Color and Shape:Solid
    Molecular weight:268.42
  • Carpro-AM1

    CAS:
    <p>Carpro-AM1, dual FAAH/COX inhibitor, IC50: 94 nM.</p>
    Formula:C21H18ClN3O
    Color and Shape:Solid
    Molecular weight:363.84
  • ASP-6537

    CAS:
    <p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>
    Formula:C17H17N3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:311.34
  • CU-32

    CAS:
    <p>CU-32 is a cGAS inhibitor with IC50=0.45 μM, blocks DNA-stimulated IFN-β production, and is selective over RIG-I-MAVS and TLRs pathways.</p>
    Formula:C11H10IN5O2
    Color and Shape:Solid
    Molecular weight:371.13
  • PD 127443

    CAS:
    <p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>
    Formula:C20H28N2O
    Color and Shape:Solid
    Molecular weight:312.45
  • TFC-007

    CAS:
    <p>TFC-007 is an H-PGDS inhibitor, reducing inflammation, useful for studying guinea pig allergic rhinitis induced by cedar pollen.</p>
    Formula:C27H29N5O4
    Purity:98.07%
    Color and Shape:Solid
    Molecular weight:487.55
  • MIF degrader MD13

    CAS:
    <p>MD13, a MIF-degrading PROTAC, disrupts vital protein interactions in cancer and inflammation, showing promise as a therapeutic research tool.</p>
    Formula:C35H35N5O8
    Color and Shape:Solid
    Molecular weight:653.68
  • Vidarabine phosphate

    CAS:
    <p>Vidarabine phosphate is an adenosine monophosphate analog.</p>
    Formula:C10H14N5O7P
    Purity:99.75%
    Color and Shape:White Crystalline Powder
    Molecular weight:347.22
  • Safrole oxide

    CAS:
    <p>Safrole oxide inhibits neuronal growth, induces apoptosis, elevates COX-2, IL-8, ROS, promoting endothelial-to-neuron-like cell transdifferentiation.</p>
    Formula:C10H10O3
    Purity:100%
    Color and Shape:Solid
    Molecular weight:178.18
  • 6,2',4'-Trimethoxyflavone

    CAS:
    <p>The compound is an Aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). It also has no short term agonist activity and no species or promoter dependence.</p>
    Formula:C18H16O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:312.32
  • Naphazoline

    CAS:
    <p>Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.</p>
    Formula:C14H14N2
    Purity:99.79%
    Color and Shape:White Crystalline Powder Solid
    Molecular weight:210.27
  • 1-Dehydro-[10]-gingerdione

    CAS:
    <p>1-Dehydro-[10]-gingerdione blocks IKKβ, curbs IκBα phosphorylation, halts NF-κB activity, and aids inflammation research.</p>
    Formula:C21H30O4
    Color and Shape:Solid
    Molecular weight:346.46
  • L-NMMA acetate

    CAS:
    <p>L-NMMA acetate inhibits all NOS types (nNOS, eNOS, iNOS); Ki: 0.18, 0.4, 6 µM respectively.</p>
    Formula:C9H20N4O4
    Purity:99.72% - 99.8%
    Color and Shape:White To Off-White Solid
    Molecular weight:248.28
  • IL-17A modulator-3

    CAS:
    <p>IL-17A modulator-3 inhibits IL-17A/A, IC50 &lt;10 μM, for inflammation, cancer, autoimmune research.</p>
    Formula:C34H50FN7O4
    Color and Shape:Solid
    Molecular weight:639.8
  • IKK2-IN-4

    CAS:
    <p>IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.</p>
    Formula:C12H11N3O2S
    Purity:>99.99%
    Color and Shape:Solid
    Molecular weight:261.3
  • Naproxen etemesil

    CAS:
    <p>Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.</p>
    Formula:C17H20O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:336.4
  • APY0201

    CAS:
    <p>APY0201: potent, specific ATP-competitive PIKfyve inhibitor; IC50=5.2 nM; blocks PtdIns3P to PtdIns(3,5)P2 conversion.</p>
    Formula:C23H23N7O
    Purity:98% - 99.74%
    Color and Shape:Solid
    Molecular weight:413.48
  • TYT-1

    CAS:
    <p>TYT-1 is a West Nile virus (WNV) inhibitor, antiviral (IC₅₀ = 0.7 mM) by blocking the pre-assembly replication step following viral entry into cells.</p>
    Formula:C21H17N3O2S3
    Purity:98.49%
    Color and Shape:Solid
    Molecular weight:439.57
  • TL8-506

    CAS:
    <p>TL8-506 is a selective and potent TLR8 agonist that induces cytokine and chemokine production.TL8-506 alleviates inflammatory and autoimmune diseases.</p>
    Formula:C20H17N3O2
    Purity:95% - 99.97%
    Color and Shape:Solid
    Molecular weight:331.37
  • L 669083

    CAS:
    <p>L 669083 is two classes of potent leukotriene biosynthesis inhibitors photoaffinity analogue.</p>
    Formula:C29H29IN4O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:672.54
  • LY 150310

    CAS:
    <p>LY 150310, a histamine H1-receptor antagonist, can alter prostanoid concentrations in vitro and in vivo.</p>
    Formula:C13H14N2
    Color and Shape:Solid
    Molecular weight:198.26
  • Fagaramide

    CAS:
    <p>Fagaramide possesses Antiplasmodial activity.</p>
    Formula:C14H17NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:247.29
  • NCX-6560

    CAS:
    <p>NCX-6560 is a novel NO-releasing derivative of atorvastatin, with those of atorvastatin.</p>
    Formula:C37H42FN3O8
    Color and Shape:Solid
    Molecular weight:675.74
  • ZXX2-77

    CAS:
    <p>ZXX2-77 is a cyclooxygenase-1 inhibitor.</p>
    Formula:C13H13ClN2O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:296.77
  • Tiazotic acid

    CAS:
    <p>Tiazotic acid is an agent with the activity of antioxidant.</p>
    Formula:C5H7N3O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:173.19
  • NLRP3-IN-25

    CAS:
    <p>NLRP3-IN-25 (compound 32), an orally available NLRP3 inhibitor, exhibits anti-inflammatory properties by attenuating renal injury in a mouse model of doxorubicin-induced glomerulonephritis and inhibiting IL-1β secretion in THP-1 cells, with an IC 50 value of 21 nM [1].</p>
    Formula:C17H19F3N4O5S
    Color and Shape:Solid
    Molecular weight:448.42
  • L 748780

    CAS:
    <p>L 748780 is a selective inducible COX-2 inhibitor.</p>
    Formula:C19H14Cl3NO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.68
  • Oxyfenamate

    CAS:
    <p>Oxyfenamate has anti-anxiety actions. It is also used in anxiety neuroses.</p>
    Formula:C11H15NO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:209.24
  • Anisodine hydrobromide

    CAS:
    <p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>
    Formula:C17H22BrNO5
    Color and Shape:White Crystals Or Crystalline Powder
    Molecular weight:400.27
  • FR20

    CAS:
    <p>FR20 is a human microsomal prostaglandin synthase 1 (mPGES 1) inhibitor.</p>
    Formula:C31H25Cl2N3O2
    Color and Shape:Solid
    Molecular weight:542.46
  • LC-R 505

    CAS:
    <p>LC-R 505 is an anti-inflammatory.</p>
    Formula:C20H26N2O5S
    Color and Shape:Solid
    Molecular weight:406.5
  • NCX1022

    CAS:
    <p>NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.</p>
    Formula:C29H35NO9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:541.59
  • GSK223

    CAS:
    GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway.
    Formula:C21H18FN3O3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:443.51
  • MIP-1072

    CAS:
    <p>MIP-1072 is the prostate-specific membrane antigen inhibitor.</p>
    Formula:C19H26IN3O7
    Purity:98%
    Color and Shape:Solid
    Molecular weight:535.33
  • hDDAH-1-IN-1

    CAS:
    <p>hDDAH-1-IN-1 is a selective non-amino acid catalytic site inhibitor of human dimethylarginine dimethylaminohydrolase-1 (hDDAH-1) (Ki: 18 μM).</p>
    Formula:C8H20N4O
    Purity:98%
    Color and Shape:Solid
    Molecular weight:188.27
  • BPK-29

    CAS:
    <p>BPK-29 disrupts NR0B1 binding and modifies C274, inhibiting growth in KEAP1-mutant cancers.</p>
    Formula:C26H32ClN3O3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:470
  • 3-OH-Kynurenamine dihydroiodide

    CAS:
    <p>3-OH-Kynurenamine dihydroiodide, the dihydroiodide form of 3-OH-Kynurenamine, functions as an activator of the aryl hydrocarbon receptor (AhR), thereby modulating the immune response. It enhances the expression of Ido1 and Tgfb1, reducing skin inflammation in psoriasis mouse models and kidney damage in nephrotoxic lupus mouse models .</p>
    Formula:C9H14I2N2O2
    Color and Shape:Solid
    Molecular weight:436.03
  • UPF-648 sodium salt

    CAS:
    <p>UPF-648 sodium salt is an inhibitor of kynurenine 3-monooxygenase (KMO) and exhibits highly active at 1 uM (81 ± 10% KMO inhibition).</p>
    Formula:C11H8Cl2NaO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:282.07
  • AHR-6293

    CAS:
    <p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>
    Formula:C15H12ClNO3
    Color and Shape:Solid
    Molecular weight:289.71
  • QM385

    CAS:
    <p>QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).</p>
    Formula:C17H18F3N7O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:409.37
  • BSP16

    CAS:
    <p>BSP16: potent, oral STING agonist; boosts interferon genes; promising for cancer research.</p>
    Formula:C16H18O5Se
    Color and Shape:Solid
    Molecular weight:369.27
  • Loxoprofenol-SRS tromethamine

    CAS:
    <p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>
    Formula:C19H31NO6
    Color and Shape:Solid
    Molecular weight:369.45
  • Avenanthramide-C methyl ester

    CAS:
    <p>Avenanthramide-C methyl ester blocks IKK/IκB phosphorylation, inhibits NF-κB, and reduces IL-6, IL-8, MCP-1 in endothelial cells (IC50 ~40 μM).</p>
    Formula:C17H15NO6
    Color and Shape:Solid
    Molecular weight:329.3
  • NPD926

    CAS:
    <p>NPD926 is an inducer of cancel cell death.</p>
    Formula:C29H35ClN2O2
    Color and Shape:Solid
    Molecular weight:479.05
  • ML388

    CAS:
    <p>ML388 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>
    Formula:C20H24N4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:320.43
  • TML-6

    CAS:
    <p>TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.</p>
    Formula:C30H37NO7
    Purity:99.71%
    Color and Shape:Solid
    Molecular weight:523.62
  • MIF-IN-4 hydrochloride

    CAS:
    <p>MIF-IN-4 hydrochloride inhibits MIF, a cytokine; has pIC50 of 5.01-6, affecting macrophage movement.</p>
    Formula:C26H29ClN6O2
    Color and Shape:Solid
    Molecular weight:493.01
  • L-Nabe

    CAS:
    <p>L-Nabe (H-Arg(NO2)-Obzl) is a effective irreversible endothelium dependent relaxation inhibitor.</p>
    Formula:C13H19N5O4
    Purity:98.03%
    Color and Shape:Solid
    Molecular weight:309.32
  • 546C88

    CAS:
    <p>546C88 is an inhibitor of nitric oxide synthase.</p>
    Formula:C7H17ClN4O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:224.69
  • AXC-715 trihydrochloride

    CAS:
    <p>AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.</p>
    Formula:C18H28Cl3N5
    Purity:99.74%
    Color and Shape:Solid
    Molecular weight:420.81
  • Etoricoxib HCl

    CAS:
    <p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>
    Formula:C18H16Cl2N2O2S
    Color and Shape:Solid
    Molecular weight:395.30
  • ABD-350

    CAS:
    <p>ABD-350 is ligand-induced inhibitor of nuclear factor kappaB phosphorylation.</p>
    Formula:C19H22F2O2
    Color and Shape:Solid
    Molecular weight:320.37
  • COX-2-IN-17

    CAS:
    <p>COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.</p>
    Formula:C20H23ClN6O2
    Color and Shape:Solid
    Molecular weight:414.89
  • AI-3

    CAS:
    <p>Nrf2/Keap1 and Keap1/Cul3 interaction inhibitor</p>
    Formula:C11H13ClO3S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:292.8
  • Phox-I1

    CAS:
    <p>Phox-I1 is a NOX2 inhibitor targeting the interactive site of p67phox with Rac GTPase.</p>
    Formula:C23H19N3O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:401.41
  • (R)-MALT1-IN-3

    CAS:
    <p>(R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).</p>
    Formula:C21H19F3N8O2
    Color and Shape:Solid
    Molecular weight:472.42
  • Avanafil dibesylate

    CAS:
    <p>Avanafil dibesylate is a PDE5 inhibitor.</p>
    Formula:C35H38ClN7O9S2
    Color and Shape:Solid
    Molecular weight:800.3
  • K-80001

    CAS:
    <p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>
    Formula:C20H17FO2
    Color and Shape:Solid
    Molecular weight:308.35
  • IMD-ferulic


    <p>IMD-ferulic, a compound that forms covalent bonds, acts as an NF-κB modulator, enhancing the adjuvanticity of small molecule immune potentiators.</p>
    Formula:C36H41N7O4
    Color and Shape:Solid
    Molecular weight:635.76
  • NCX 466

    CAS:
    <p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>
    Formula:C20H24N2O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:436.41