Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(143 products)
- CXCR(158 products)
- Cell wall(5 products)
- IL Receptor(105 products)
- IκB/IKK(58 products)
- LTR(3 products)
- MALT(25 products)
- MRP(6 products)
- NADPH-oxidase(2 products)
- NF-κB(389 products)
- NOD(25 products)
- NOS(61 products)
- Nrf2(81 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(59 products)
- TLR(74 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3396 products of "Immunology and Inflammation"
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IKZF1-degrader-2
CAS:IKZF1-degrader-2 (Compound 3), an IKZF1 degrader, exhibits anticancer activity and low toxicity [1].Formula:C33H30FN5O5Color and Shape:SolidMolecular weight:595.62Anti-inflammatory agent 9
Benzimidazothiazole-derived Compound 28 from tilomisole targets COX-2, has potent anti-inflammatory effects & is orally bioavailable.Formula:C18H15N5O2SColor and Shape:SolidMolecular weight:365.41MSA-2 dimer
CAS:MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.Formula:C29H28O8S2Color and Shape:SolidMolecular weight:568.66SP4206
CAS:SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)Formula:C30H37Cl2N7O6Purity:98%Color and Shape:SolidMolecular weight:662.56Gardiquimod hydrochloride
CAS:Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formula:C17H24ClN5OColor and Shape:SolidMolecular weight:349.858EGR-1-IN-3
CAS:EGR-1-IN-3 (Compound 36) is an inhibitor of early growth response 1 (EGR-1) binding to DNA. It effectively suppresses the binding of EGR-1 to DNA and the expression of inflammation-related genes (such as TSLP, IL-31, IL-6, and CCL2) induced by TNFα. This compound is applicable to the study of inflammatory diseases.Formula:C31H31N3O6SColor and Shape:SolidMolecular weight:573.659Creatine ethyl ester
CAS:Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.Formula:C6H13N3O2Color and Shape:SolidMolecular weight:159.186OP-5244
CAS:OP-5244 has comparable potency to bisphosphonic acid series and targets CD73.Formula:C19H29ClN5O9PPurity:98%Color and Shape:SolidMolecular weight:537.89TLR7/8 antagonist 1
Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.Formula:C24H27N5O2Color and Shape:SolidMolecular weight:417.5IRAK4 modulator-1
CAS:IRAK4 Modulator-1 (example 161), an IRAK4 modulator with an IC50 of 4.647 μM, is employed in the investigation of IRAK-mediated disorders [1].Formula:C19H13ClN4O2Color and Shape:SolidMolecular weight:364.79C5aR-IN-3
CAS:C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.Formula:C36H40FN5O3Color and Shape:SolidMolecular weight:609.73NLRP3-IN-78
CAS:NLRP3-IN-78 (compound 21) is an NLRP3 inhibitor with a 46.72% inhibition rate of GSDMD-induced pyroptosis at 5 μM. It binds to the NLRP3 protein and prevents GSDMD-NT oligomerization. Additionally, NLRP3-IN-78 inhibits GSDMD cleavage and upstream NF-κB signaling, demonstrating anti-inflammatory activity.Formula:C12H5Cl2N3O4S2Color and Shape:SolidMolecular weight:390.222STAT1/3-IN-1
CAS:STAT1/3-IN-1 (Compound 6k) is an inhibitor of STAT1/3 phosphorylation. It prevents the phosphorylation and nuclear translocation of STAT1/3. Additionally, STAT1/3-IN-1 inhibits the inflammatory enzymes iNOS and COX-2. This compound exhibits anti-inflammatory properties by reducing pro-inflammatory cytokines, such as IL-1β, IL-6, and TNF-α, without significant cytotoxicity.Formula:C28H25ClN6O5Color and Shape:SolidMolecular weight:560.988HG-12-6
CAS:HG-12-6 is a type II IRAK4 inhibitor, targeting its inactive form with an IC50 of 165 nM, and is used in autoimmunity and inflammation.Formula:C29H27F3N6O2SPurity:98%Color and Shape:SolidMolecular weight:580.62RGT-068A
CAS:RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor .Formula:C17H16ClN9O2Color and Shape:SolidMolecular weight:413.82TBK1/IKKε-IN-1
CAS:TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).Formula:C28H26N4O5Purity:98%Color and Shape:SolidMolecular weight:498.5320-Hydroxyvitamin D3
CAS:20-Hydroxyvitamin D3 (20(OH)D3) is a hydroxy metabolite of vitamin D3. It functions as a ligand for the vitamin D receptor (VDR), aryl hydrocarbon receptor (AhR), liver X receptor (LXR), and retinoic acid receptor-related orphan receptor (ROR). 20-Hydroxyvitamin D3 inhibits cell proliferation and induces differentiation. It is applicable in research on inflammatory and autoimmune diseases.Formula:C27H44O2Color and Shape:SolidMolecular weight:400.637OP-5244 sodium
OP-5244 sodium: potent oral CD73 inhibitor (IC50: 0.25 nM), potential in cancer research by hindering adenosine, reversing immunosuppression.Formula:C19H28ClN5NaO9PColor and Shape:SolidMolecular weight:559.87Anti-inflammatory agent 6
Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.Formula:C22H20O12Color and Shape:SolidMolecular weight:476.39COX-2-IN-9
COX-2-IN-9: potent oral COX-2 blocker, selective over Celecoxib, IC50 10.17 μM, less ulcers, strong anti-inflammatory.Formula:C25H23N5O4S2Color and Shape:SolidMolecular weight:521.61CD73-IN-18
CAS:CD73-IN-18 (compound 35j) is an orally effective inhibitor of the extracellular 5'-nucleotidase (CD73) enzyme. It can be utilized in anticancer research.Formula:C20H17N5O3Color and Shape:SolidMolecular weight:375.38Nrf2 activator-6
CAS:Nrf2 activator-6, a tetrahydroisoquinoline, inhibits Kelch-Nrf2 at 5 nM IC50 (WO2021214470A1).Formula:C31H37ClFN5O5Color and Shape:SolidMolecular weight:614.11AIM4
CAS:AIM4 is a compound known for inhibiting TDP-43 aggregation. It demonstrates good biocompatibility and anti-inflammatory activity, making it a valuable agent in research for diseases such as amyotrophic lateral sclerosis (ALS).Formula:C25H23Br2N5O4Color and Shape:SolidMolecular weight:617.289AHR antagonist 5 hemimaleate
Potent oral AHR antagonist with IC50 < 0.5 μM, hinders tumor growth with anti-PD-1.Formula:C29H28FN7O4Color and Shape:SolidMolecular weight:499.55SARM1-IN-4
CAS:SARM1-IN-4 (Compound 7) is an orally active SARM1 inhibitor that reduces plasma neurofilament light chain (NfL) levels in a mouse model following a 50 mg/kg oral dose. By inhibiting the NAD+ hydrolase activity of SARM1, it prevents programmed axon degeneration, making it useful for research in neurodegenerative and neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, and peripheral neuropathy.Formula:C13H17F2N3O2Color and Shape:SolidMolecular weight:285.29COX-2/PI3K-IN-1
COX-2/PI3K-IN-1 (compound 5d) is a potent inhibitor of PI3K (IC50: 1.14 nM). COX-2/PI3K-IN-1 is a selective inhibitor of COX-2 (Ki: 3.24 nM).Formula:C19H14ClN5S2Color and Shape:SolidMolecular weight:411.93LHC-165
CAS:LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.Formula:C29H32F2N3O7PPurity:98%Color and Shape:SolidMolecular weight:603.55Antioxidant agent-3
Antioxidant agent-3 shows strong DPPH and ABTS+ radical scavenging (IC50: 26.58, 30.31 μM). Boosts ROS, SOD, GSH; lowers LDH in H2O2-exposed HepG2 cells.Formula:C18H14O8Color and Shape:SolidMolecular weight:358.3G108
CAS:G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.Formula:C16H14Cl2N4O2Purity:99.13% - 99.75%Color and Shape:SolidMolecular weight:365.21CD73-IN-7
CAS:CD73-IN-7: potent inhibitor of CD73, blocks adenosine production to treat tumors.Formula:C13H11ClN4O2Color and Shape:SolidMolecular weight:290.7NLRP3-IN-7
NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome.Formula:C18H15ClN2O4S3Color and Shape:SolidMolecular weight:454.97IRAK4-IN-19
IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.Formula:C25H26F2N8OColor and Shape:SolidMolecular weight:492.52CD73-IN-12
CD73-IN-12, a compound from CN114437038A, shows strong anti-tumor activity by effectively inhibiting CD73 enzyme.Formula:C17H14F2N4O2Color and Shape:SolidMolecular weight:344.32MALT1-IN-11
CAS:MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.Formula:C20H16F4N8OColor and Shape:SolidMolecular weight:460.39cGAS-IN-4
CAS:cGAS-IN-4 (Compound 36) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) with IC50 values of 32 nM for human cGAS (h-cGAS) and 5.8 nM for mouse cGAS (m-cGAS). In THP-1 cells, cGAS-IN-4 inhibits cGAMP with an IC50 of 60 nM, enhancing cellular potency. Additionally, cGAS-IN-4 exhibits anti-inflammatory effects in a mouse model of Concanavalin A-induced acute liver injury.Formula:C19H18Cl2N4O3Color and Shape:SolidMolecular weight:421.277Heme Oxygenase-2-IN-1
Heme Oxygenase-2-IN-1 is a selective HO-2 inhibitor with IC50s: 14.9 μM (HO-1), 0.9 μM (HO-2).Formula:C19H17N3O2Color and Shape:SolidMolecular weight:319.36Methoxyurea
CAS:Methoxyurea (Compound 3) is a potential modulator of nitric oxide (NO) donors, interacting with hemoglobin forms such as oxyhemoglobin (OxyHb) and methemoglobin (MetHb). It holds promise for use in research on sickle cell disease (SCD).Formula:C2H6N2O2Color and Shape:SolidMolecular weight:90.081Cyclic-di-GMP sodium
c-di-GMP sodium: STING activator, regulates bacteria biofilm, motility, virulence.Formula:C20H24N10NaO14P2Color and Shape:SolidMolecular weight:713.08464YM-I-26
CAS:YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of β-amyloid in murine microglial BV2 cells and reduces the production of IL-1β and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.Formula:C28H33ClN2O5S2Color and Shape:SolidMolecular weight:577.16Hetrombopag olamine
CAS:Hetrombopag olamine is a non-peptide thrombopoietin (TPO) receptor agonist with oral activity.Formula:C29H36N6O7Purity:98%Color and Shape:SolidMolecular weight:580.63ASP-8731
CAS:ASP8731 is a selective inhibitor of BACH1 that prevents inflammation and vascular occlusion, and induces fetal hemoglobin in sickle cell disease.Formula:C20H21N5O4Color and Shape:SolidMolecular weight:395.41RuDiOBn
CAS:RuDiOBn exhibits low antioxidant activity by scavenging DPPH and ABTS free radicals with scavenging rates of 13.2% and 5.9% at a concentration of 100 μg/mL. It inhibits collagen glycation and reduces the formation of advanced glycation end-products (AGE) with an IC50 of 2.45 μg/mL. RuDiOBn also enhances fibroblast proliferation and migration, stimulates collagen synthesis, and aids in skin repair and regeneration while inhibiting collagenase.
Formula:C29H22O7Color and Shape:SolidMolecular weight:482.481COX-1/2-IN-2
COX-1/2-IN-2, a potent dual inhibitor, has IC50s: COX-1 at 9.7μM & COX-2 at 4.6μM.Formula:C15H10ClIN2OColor and Shape:SolidMolecular weight:396.61ADU-S100 disodium salt
CAS:ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).Formula:C20H22N10Na2O10P2S2Purity:98%Color and Shape:SolidMolecular weight:734.51AS2690168 hydrochloride
CAS:AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.Formula:C17H15Cl2F3N4OColor and Shape:SolidMolecular weight:419.228NOD1-IN-1
CAS:NOD1/2-IN-1 (Compound 2) is a potent inhibitor of RIPK2 with an IC50 value of 0.65 nM as determined by the ADP-Glo assay. It selectively inhibits the NOD1 pathway, with an IC50 of 33 nM, effectively blocking the production of pro-inflammatory cytokines and thereby reducing inflammatory responses. This compound has potential applications in the research of colitis.Formula:C16H14ClN3O3Color and Shape:SolidMolecular weight:331.75DEG-35
CAS:DEG-35 is a CRBN-dependent bifunctional degrader targeting IKZF2 and CK1α, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. It activates the p53 apoptotic pathway and is applicable for research related to acute myeloid leukemia (AML).Formula:C25H21N3O5Color and Shape:SolidMolecular weight:443.456,2′,4′-Trimethoxyflavone
CAS:6,2′,4′-Trimethoxyflavone is an AhR antagonist that does not demonstrate effective protection against ischemia-reperfusion injury in the brain of Sprague-Dawley rats.Formula:C18H18O5Color and Shape:SolidMolecular weight:314.332CPDT
CAS:CPDT is an orally active and potent inducer of phase 2 enzymes as well as an activator of Nrf2. CPDT enhances the activity of critical phase 2 enzymes, such as glutathione S-transferase, NAD(P)H:quinone oxidoreductase 1, and gamma-glutamylcysteine synthetase, and increases glutathione levels both in the bladder of rats and in bladder cells in vitro.Formula:C6H6S3Color and Shape:SolidMolecular weight:174.307α-Gracinoic acid
CAS:α-Gracinoic acid acts as an inhibitor of mPGES-1, exhibiting anti-inflammatory properties.Formula:C29H42O4Color and Shape:SolidMolecular weight:454.64Yoda2
CAS:Yoda2 (KC289), the potassium salt of Yoda1, is an agonist of PIEZO1 with an EC50 of 150 nM. It induces Ca2+ elevation in HeLa cells and can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50= 1.2 μM). Additionally, Yoda2 is capable of stimulating NOS3 and promoting NO production.Formula:C16H9Cl2KN2O2S2Color and Shape:SolidMolecular weight:435.39IRAK4-IN-15
CAS:IRAK4-IN-15: selective IRAK4 inhibitor, IC50 0.002 μM, good PK, low clearance, synergizes with Acalabrutinib in MyD88/CD79 mutant ABC-DLBCL.Formula:C25H29FN10Color and Shape:SolidMolecular weight:488.56SMW139
CAS:SMW139 is a selective allosteric antagonist of the P2X7 receptor, exhibiting a Ki value of 32 nM for human P2X7R. In rat liver microsomes, its half-life is 47 minutes. SMW139 is applicable in research related to inflammation, Alzheimer's disease, and multiple sclerosis.Formula:C19H21ClF3NO2Color and Shape:SolidMolecular weight:387.824STING agonist-20
CAS:STING agonist-20: potent, aids in XMT-2056 synthesis, used as a cancer vaccine adjuvant.Formula:C36H39N11O8Color and Shape:SolidMolecular weight:753.76KI696
CAS:KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Formula:C28H30N4O6SPurity:99.74%Color and Shape:SolidMolecular weight:550.63Ref: TM-T11758L
1mg137.00€5mg281.00€1mL*10mM (DMSO)341.00€10mg423.00€25mg707.00€50mg1,018.00€100mg1,468.00€200mg1,963.00€VVD-130037
CAS:VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Formula:C17H17ClN4O2Purity:99.01% - 99.92%Color and Shape:SolidMolecular weight:344.8Ref: TM-T88838
1mg72.00€5mg157.00€1mL*10mM (DMSO)171.00€10mg242.00€25mg387.00€50mg546.00€100mg1,429.00€UBS109
CAS:UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.Formula:C18H17N3OPurity:99.48%Color and Shape:SolidMolecular weight:291.35Ref: TM-T88314
2mg37.00€5mg54.00€1mL*10mM (DMSO)59.00€10mg87.00€25mg157.00€50mg241.00€100mg369.00€200mg536.00€Dazostinag disodium
CAS:Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.Formula:C21H20F2N8Na2O10P2S2Purity:98.84% - 99.96%Color and Shape:SolidMolecular weight:754.48AM103
CAS:AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).Formula:C36H38N3NaO4SPurity:99.75%Color and Shape:SolidMolecular weight:631.76HOIPIN-8 sodium
CAS:HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.Formula:C23H15F2N4NaO3Purity:97.34%Color and Shape:SolidMolecular weight:456.38Ref: TM-T62826
1mg66.00€5mg145.00€1mL*10mM (DMSO)146.00€10mg224.00€25mg358.00€50mg512.00€100mg707.00€200mg973.00€Evixapodlin
CAS:Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.Formula:C34H36Cl2N8O4Purity:97.02%Color and Shape:SolidMolecular weight:691.61Ref: TM-T36487
1mg111.00€5mg264.00€1mL*10mM (DMSO)405.00€10mg424.00€25mg747.00€50mg1,008.00€100mg1,359.00€200mg1,833.00€Antiproliferative agent-22
CAS:Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.Formula:C17H13N3O3Purity:99.20% - 99.27%Color and Shape:SolidMolecular weight:307.32-Selenouracil
CAS:2-Selenouracil is a specialized photosensitizer for photodynamical therapy.Formula:C4H4N2OSeColor and Shape:SolidMolecular weight:175.05NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Formula:C22H26Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:421.36Veledimex
CAS:Veledimex is an oral activator ligand for a proprietary gene therapy promoter system. It is also a moderate inhibitor of and substrate for CYP3A4/5.Formula:C27H38N2O3Purity:98%Color and Shape:SolidMolecular weight:438.6PSB-12379
CAS:PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).Formula:C18H23N5O9P2Purity:98%Color and Shape:SolidMolecular weight:515.35(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Formula:C24H31FO6Purity:99%Color and Shape:SolidMolecular weight:434.4977Ref: IN-DA0039HQ
Discontinued product11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Formula:C21H30O5Purity:98%Color and Shape:SolidMolecular weight:362.4599Ref: IN-DA003AAY
Discontinued product9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Formula:C22H29FO5Purity:99%Color and Shape:SolidMolecular weight:392.4611Ref: IN-DA0034OW
Discontinued productα-Terpineol
CAS:Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Formula:C10H18OPurity:97.55%Color and Shape:Colorless LiquidMolecular weight:154.2511β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS:Formula:C21H28O5Purity:98%Color and Shape:SolidMolecular weight:360.4440Xibornol
CAS:Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formula:C18H26OColor and Shape:SolidMolecular weight:258.4Ref: TM-T35177
Discontinued productNogapendekin alfa inbakicept
CAS:Nogapendekin alfa inbakicept is an IL-15 superagonist that enhances anti-tumor immune responses by activating NK cells and T cells. It is being studied for use in non-muscle invasive bladder cancer (NMIBC).Color and Shape:SolidElamipretide acetate
Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.
Formula:C34H53N9O7Purity:99.76%Color and Shape:SoildMolecular weight:699.84Ref: TM-TP1095L
Discontinued productAurothioglucose
CAS:Aurothioglucose is a active-site TrxR1 inhibitor.Formula:C6H11AuO5SPurity:98%Color and Shape:Yellow Crystals SolidMolecular weight:392.18Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.Formula:C67H127F3N10O14SPurity:99.90%Color and Shape:SoildMolecular weight:1385.84gp91ds-tat
gp91ds-tat is a useful organic compound for research related to life sciences and the catalog number is T35393.
Purity:98%Color and Shape:SolidIcatolimab
Icatolimab (JS-004) is a humanized antibody targeting BTLA/CD272 for the study of lymphomas and solid tumors.
Purity:98.7% (SDS-PAGE); 95.6% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.6% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaRef: TM-T77490
Discontinued productMagnesium citrate
CAS:Magnesium citrate is a useful organic compound for research related to life sciences. The catalog number is T64455 and the CAS number is 3344-18-1.Formula:C12H10Mg3O14Color and Shape:SolidMolecular weight:451.113Di-O-methyldemethoxycurcumin
CAS:Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.Formula:C22H22O5Purity:98%Color and Shape:SolidMolecular weight:366.41STING agonist-22
CAS:STING agonist-22 (CF501) boosts vaccines by activating STING, inducing IFN-I and cytokines, aiding in SARS-CoV-2 research.
Formula:C40H48N14O6Color and Shape:SolidMolecular weight:820.9Racemic Naproxen
CAS:Racemic Naproxen is a biochemical substance.Formula:C14H14O3Purity:98%Color and Shape:Crystals From Acetone-Hexane White SolidMolecular weight:230.26JH-X-119-01 hydrochloride
CAS:JH-X-119-01 hydrochloride is a potent, selective inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) that effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice.Formula:C25H21ClN6O3Color and Shape:SolidMolecular weight:488.93Tacalcitol
CAS:Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.Formula:C27H44O3Purity:98%Color and Shape:SolidMolecular weight:416.64TLQP-21 TFA
TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.
Purity:98%Color and Shape:LiquidTLR7/8/9 antagonist 2
CAS:TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.Formula:C23H31N7Purity:98%Color and Shape:SoildMolecular weight:405.54Tripeptide-41
CAS:Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.Formula:C29H30N4O5Purity:98%Color and Shape:SolidMolecular weight:514.57RIDR-PI-103
CAS:RIDR-PI-103 is a reactive oxygen species (ROS)-induced drug release prodrug featuring an autocyclized portion connected to the pan-PI3K inhibitor (PI-103). In MDA-MB-361 and MDA-MB-231 cells, Doxorubicin and RIDR-PI-103 exhibited synergistic inhibition of cancer cell proliferation.Formula:C27H25N7O4Color and Shape:SolidMolecular weight:511.532,3-Bis(3-indolylmethyl)indole
CAS:2,3-Bis(3-indolylmethyl)indole exhibits a concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption.Formula:C26H21N3Color and Shape:SolidMolecular weight:375.475ARGX-112
CAS:Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.
Color and Shape:Odour LiquidALPK1-IN-2
CAS:ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).
Formula:C20H18F2N4O2SColor and Shape:SolidMolecular weight:416.44L-NIO dihydrochloride
CAS:L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.Formula:C7H16ClN3O2Purity:98%Color and Shape:SolidMolecular weight:209.67ALPK1-IN-1
CAS:ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.
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CAS:ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced
Formula:C20H16F2N4OSPurity:98%Color and Shape:SolidMolecular weight:398.43
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