Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(142 products)
- CXCR(159 products)
- Cell wall(5 products)
- IL Receptor(110 products)
- IκB/IKK(58 products)
- LTR(3 products)
- MALT(25 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(425 products)
- NOD(21 products)
- NOS(61 products)
- Nrf2(82 products)
- PGE Synthase(31 products)
- ROS(70 products)
- TGF-beta/Smad(63 products)
- TLR(73 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3389 products of "Immunology and Inflammation"
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TLR7 agonist 28
CAS:TLR7 agonist28 (compound 3) is a potent TLR7 agonist. This compound can be combined with anti-tumor monoclonal antibodies (mAb) for use in cancer immunotherapy.Formula:C26H25N9O7Color and Shape:SolidMolecular weight:575.533mPGES1-IN-5
CAS:mPGES1-IN-5 (compound 18) is a multi-substituted pyrimidine compound that acts as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and demonstrates significant inhibitory activity in vivo against acute inflammation models.Formula:C27H27N3OColor and Shape:SolidMolecular weight:409.52TMV-IN-8
CAS:TMV-IN-8 (compound 7d) is an anti-tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL. TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppresses TMV coat protein gene expression and biosynthesis process [1].Formula:C26H22N6O4Color and Shape:SolidMolecular weight:482.49WK692
CAS:Compound WK692 (compund WK692) is a BCL6 inhibitor that effectively suppresses the growth of diffuse large B-cell lymphoma cells without toxic side effects and acts synergistically with inhibitors of EZH2 and PRMT5.Formula:C26H28Br2N8O5Color and Shape:SolidMolecular weight:692.36ASP-8731
CAS:ASP8731 is a selective inhibitor of BACH1 that prevents inflammation and vascular occlusion, and induces fetal hemoglobin in sickle cell disease.Formula:C20H21N5O4Color and Shape:SolidMolecular weight:395.41CD73-IN-12
CD73-IN-12, a compound from CN114437038A, shows strong anti-tumor activity by effectively inhibiting CD73 enzyme.Formula:C17H14F2N4O2Color and Shape:SolidMolecular weight:344.32Methoxyurea
CAS:Methoxyurea (Compound 3) is a potential modulator of nitric oxide (NO) donors, interacting with hemoglobin forms such as oxyhemoglobin (OxyHb) and methemoglobin (MetHb). It holds promise for use in research on sickle cell disease (SCD).Formula:C2H6N2O2Color and Shape:SolidMolecular weight:90.081COX-2/NO-IN-1
COX-2/NO-IN-1: oral iNOS & NO blocker (IC50=3.52μM), COX-2 supressor, anti-inflammatory, protects kidneys.Formula:C15H15NO3Color and Shape:SolidMolecular weight:257.28iNOs-IN-1
iNOs-IN-1 (YPW) is a strong iNOS inhibitor with dose-dependent anti-inflammatory properties, reducing IL-6, iNOS, and NO levels.Formula:C25H30N4O5Color and Shape:SolidMolecular weight:466.53FAPI-74
CAS:FAPI-74 is a PET (positron emission tomography) tracer involved in early FAPI-PET imaging.FAPI-74 can be used to study cancer tumors and degenerative diseases.
Formula:C36H49N9O8Color and Shape:SolidMolecular weight:735.83NDT-30805
NDT-30805, a triazolopyridine, blocks IL-1β in PBMC (IC50: 0.013μM) & NLRP3 inflammasome, for inflammation research.Formula:C23H22N6SColor and Shape:SolidMolecular weight:414.53SLC7A11-IN-2
CAS:SLC7A11-IN-2 (Compound 1) is an inhibitor of SLC7A11/xCT. It disrupts the oxidative balance in HeLa cells by decreasing intracellular glutathione levels and increasing oxidative stress, thereby inducing cell death with an IC50 of 10.23 μM. Molecular dynamics simulations have demonstrated that SLC7A11-IN-2 exhibits a stronger binding affinity to SLC7A11 compared to Erastin. This compound is useful for research in the field of cervical cancer.Formula:C19H24N4O3Color and Shape:SolidMolecular weight:356.42Keap1-Nrf2-IN-5
CAS:Keap1-Nrf2-IN-5 is a potent inhibitor of Keap1-Nrf2 PPI (Keap1-Nrf2 protein-protein interaction) (IC50: 4.1 μM, Kd: 3.7 μM).Formula:C23H30N4O6SColor and Shape:SolidMolecular weight:490.57Hypoxystat
CAS:Hypoxystat increases the affinity of hemoglobin for oxygen, thereby reducing the release of oxygen to tissues and inducing tissue hypoxia. [Hypoxystat] can alleviate mitochondrial disorder Leigh syndrome in Ndufs4 gene knockout mouse models. Hypoxystat is orally active.Formula:C21H21NO5Color and Shape:SolidMolecular weight:367.395BMY-25551
CAS:BMY-25551, a Mitomycin A analog, exhibits cytotoxicity 8 to 20 times greater than Mitomycin C against both murine and human tumor cell lines. It is applicable in research pertaining to cancer and hematological disorders.Formula:C17H21N3O7Color and Shape:SolidMolecular weight:379.36PB01
CAS:PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively suppresses high glucose-induced ROS generation and mitochondrial superoxide production while significantly reducing the cellular expression of DPP-4. Additionally, PB01 notably lowers blood glucose levels in diabetic mice. It demonstrates excellent safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds promise for research in the diabetes field.Formula:C18H21N5O3Color and Shape:SolidMolecular weight:355.391A-9758
CAS:A-9758: RORγt selective inverse agonist, IC50 5nM, inhibits IL-17A, Th17, and treats psoriasis.Formula:C25H23Cl2F3N2O3Purity:98%Color and Shape:SolidMolecular weight:527.36(R)-Ketoprofen
CAS:(R)-Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that exhibits oral activity and analgesic properties. Unlike its counterpart, (R)-Ketoprofen does not significantly enhance the increase of inflammatory cytokines (such as Tumor Necrosis Factor (TNF) and Interleukin-1 (IL-1)) induced by LPS. However, it can inhibit the anti-inflammatory activity of (S)-Ketoprofen.Formula:C16H14O3Color and Shape:SolidMolecular weight:254.28VS-15
CAS:VS-15 is a selective inhibitor of IDO1, specifically binding to its apo-heme form. Additionally, VS-15 serves as an inhibitor of iNOS.Formula:C29H27N5O3Color and Shape:SolidMolecular weight:493.56NLRP3-IN-53
CAS:NLRP3-IN-53 (compound 1) is an NLRP3 inhibitor with an IC50 of 3.4nM.Formula:C22H27N5O4Color and Shape:SolidMolecular weight:425.48BMS-986458
CAS:BMS-986458 is a highly selective, orally active BCL6 PROTAC degrader. It specifically targets cereblon (CRBN) and the BCL6 N-terminal BTB domain to catalyze proximity-induced BCL6 degradation. BMS-986458 is applicable for research in B-cell non-Hodgkin lymphoma.Formula:C32H34ClN9O3Color and Shape:SolidMolecular weight:628.124mPGES1-IN-4
CAS:mPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.Formula:C27H25F2N3OColor and Shape:SolidMolecular weight:445.50S-MTC acetate
CAS:S-MTC acetate (S-Methyl-L-thiocitrulline acetate) serves as a potent inhibitor of inducible nitric oxide synthases and is especially effective in inhibiting the constitutive (neuronal) type rather than the inducible (endothelial) type.Formula:C9H19N3O4SColor and Shape:SolidMolecular weight:265.336,2′,4′-Trimethoxyflavone
CAS:6,2′,4′-Trimethoxyflavone is an AhR antagonist that does not demonstrate effective protection against ischemia-reperfusion injury in the brain of Sprague-Dawley rats.Formula:C18H18O5Color and Shape:SolidMolecular weight:314.332Cryptopleurine
CAS:Cryptopleurine is an inhibitor of gene products associated with cell proliferation, survival, invasion and angiogenesis. It acts by targeting the NF-κB pathway.Formula:C24H27NO3Purity:98%Color and Shape:SolidMolecular weight:377.48E 5090
CAS:E5090 is a novel orally active inhibitor of IL-1 generation. It also has anti-inflammatory properties.Formula:C19H20O5Purity:98%Color and Shape:SolidMolecular weight:328.36COX-2/15-LOX-IN-5
CAS:COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-κB activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.Formula:C25H21N3O3SColor and Shape:SolidMolecular weight:443.52Anti-inflammatory agent 10
Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.Formula:C17H13BrN4O3S2Color and Shape:SolidMolecular weight:465.34XO/COX/LOX-IN-1
XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.Formula:C24H20N4O2SColor and Shape:SolidMolecular weight:428.51Galectin-3-IN-2
Galectin-3-IN-2 inhibits galactose lectin-3 (Gal-3) with an 8.3 μM IC50, impacting cancer-related metabolism.Formula:C24H30FN3O10SColor and Shape:SolidMolecular weight:571.57meso-Zeaxanthin
CAS:meso-Zeaxanthin accumulates in the central retina and, together with lutein and zeaxanthin, forms the macular pigment, which functions as a light filter. meso-Zeaxanthin can quench reactive oxygen species (ROS), thereby exhibiting antioxidant properties.Formula:C40H56O2Color and Shape:SolidMolecular weight:568.871COX-2-IN-7
COX-2-IN-7: potent, orally active COX-2 inhibitor with higher selectivity than Celecoxib, IC50 6.585 uM, anti-inflammatory, low ulcer risk.Formula:C15H13N3O2S2Color and Shape:SolidMolecular weight:331.41Numidargistat
CAS:CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).Formula:C11H22BN3O5Purity:98%Color and Shape:SolidMolecular weight:287.12NOTA-FAPI
CAS:NOTA-FAPI is a FAP inhibitor and FAPI-4 analogue used in PET imaging and targeted therapy for FAP-overexpressing pathological conditions.Formula:C36H47F2N9O8Purity:99.748%Color and Shape:SolidMolecular weight:771.81ABZI
CAS:(S)-2-(1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1-(2-hydroxy-2-phenylethyl)-1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing the crucial amide benzimidazole (ABZI) component. It consistently inhibits the binding of 3 H-cGAMP to STING, with an apparent inhibition constant (IC50) of 14 μM. This compound is applicable in tumor research.Formula:C23H24N6O3Color and Shape:SolidMolecular weight:432.48AMC-04
CAS:AMC-04 is a protein response (UPR) activator that initiates the UPR pathway via ROS and p38 MAPK signaling, leading to apoptotic cell death. It is used in cancer research [1].Formula:C26H28N2O3Color and Shape:SolidMolecular weight:416.51NLRP3-IN-8
CAS:NLRP3-IN-8, orally active inflammasome blocker, IC50 of 1.23μM, stable (t1/2 = 138.63min), non-toxic (IC50 >100μM).Formula:C23H20N2O6Color and Shape:SolidMolecular weight:420.41COX-2/PI3K-IN-2
COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).Formula:C16H17N5O2Color and Shape:SolidMolecular weight:311.34Factor B-IN-4
CAS:Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.Formula:C27H32N2O4Color and Shape:SolidMolecular weight:448.55IRAK1/4/pan-FLT3 Kinase-IN-2
CAS:IRAK1/4/pan-FLT3 Kinase-IN-2 (compound 27) is a potent dual inhibitor of IRAK1/4 and FLT3 with IC50 values of 10 nM, 0.7 nM, and < 0.5 nM, respectively. This compound enhances survival in mice models of acute myeloid leukemia.Formula:C20H22F3N5OColor and Shape:SolidMolecular weight:405.42IRAK4-IN-31
CAS:IRAK4-IN-31 is a crystalline inhibitor of IRAK4. It is applicable in research related to myelodysplastic syndromes (MDS).Formula:C27H33N5O5Color and Shape:SolidMolecular weight:507.58HPK1-IN-56
CAS:HPK1-IN-56 (Compound A29) is an HPK1 inhibitor with an IC50 of 2.70 nM. It inhibits downstream p-SLP76 in Jurkat T cells with an IC50 of 8.1 nM. Additionally, HPK1-IN-56 induces IL-2 production in human PBMCs. This compound exhibits anticancer properties, enhancing T cell cytotoxicity and the antitumor efficacy of anti-PD-1 antibodies.Formula:C24H26N8OColor and Shape:SolidMolecular weight:442.516DEG-35
CAS:DEG-35 is a CRBN-dependent bifunctional degrader targeting IKZF2 and CK1α, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. It activates the p53 apoptotic pathway and is applicable for research related to acute myeloid leukemia (AML).Formula:C25H21N3O5Color and Shape:SolidMolecular weight:443.45mPGES-1-IN-1
MPGES-1, potential anti-inflammatory drug target, has IC50 of 0.03 μM with mPGES-1-IN-1.Formula:C21H14N4O2SColor and Shape:SolidMolecular weight:386.43iNOS/PGE2-IN-1
iNOS/PGE2-IN-1: iNOS/PGE2 inhibitor, reduces LPS-induced NO, low ulcer risk, anti-inflammatory.Formula:C26H22ClN3O4Color and Shape:SolidMolecular weight:475.92MG-T-19
CAS:MG-T-19, a TIM-3 inhibitor, inhibit the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs.Formula:C18H8Br2ClF3N4O2SPurity:99.14%Color and Shape:SolidMolecular weight:596.6Ref: TM-T201721
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€200mg2,555.00€Factor B-IN-3
CAS:Factor B-IN-3 is a potent inhibitor of complement factor B. Factor B-IN-3 can be used to study inflammatory and immune-related diseases.Formula:C24H29N3O4Color and Shape:SolidMolecular weight:423.5HOIPIN-8 sodium
CAS:HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.Formula:C23H15F2N4NaO3Purity:97.34%Color and Shape:SolidMolecular weight:456.38Ref: TM-T62826
1mg70.00€5mg154.00€10mg235.00€25mg378.00€50mg540.00€100mg747.00€200mg1,026.00€1mL*10mM (DMSO)155.00€VVD-130037
CAS:VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Formula:C17H17ClN4O2Purity:99.01% - 99.92%Color and Shape:SolidMolecular weight:344.8Ref: TM-T88838
1mg148.00€5mg357.00€10mg522.00€25mg833.00€50mg1,103.00€100mg1,508.00€1mL*10mM (DMSO)390.00€AM103
CAS:AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).Formula:C36H38N3NaO4SPurity:99.75%Color and Shape:SolidMolecular weight:631.76KI696
CAS:KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Formula:C28H30N4O6SPurity:99.74%Color and Shape:SolidMolecular weight:550.63Ref: TM-T11758L
1mg144.00€5mg298.00€10mg445.00€25mg747.00€50mg1,074.00€100mg1,549.00€200mg2,072.00€1mL*10mM (DMSO)360.00€Evixapodlin
CAS:Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.Formula:C34H36Cl2N8O4Purity:97.02%Color and Shape:SolidMolecular weight:691.61Ref: TM-T36487
1mg111.00€5mg264.00€10mg424.00€25mg747.00€50mg1,008.00€100mg1,359.00€200mg1,833.00€1mL*10mM (DMSO)405.00€UBS109
CAS:UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.Formula:C18H17N3OPurity:99.48%Color and Shape:SolidMolecular weight:291.35Ref: TM-T88314
2mg38.00€5mg57.00€10mg92.00€25mg166.00€50mg254.00€100mg389.00€200mg566.00€1mL*10mM (DMSO)63.00€Antiproliferative agent-22
CAS:Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.Formula:C17H13N3O3Purity:99.20% - 99.27%Color and Shape:SolidMolecular weight:307.3Dazostinag disodium
CAS:Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.
Formula:C21H20F2N8Na2O10P2S2Purity:98.84% - 99.96%Color and Shape:SolidMolecular weight:754.482-Selenouracil
CAS:2-Selenouracil is a specialized photosensitizer for photodynamical therapy.Formula:C4H4N2OSeColor and Shape:SolidMolecular weight:175.05PSB-12379
CAS:PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).Formula:C18H23N5O9P2Purity:98%Color and Shape:SolidMolecular weight:515.35Veledimex
CAS:Veledimex is an oral activator ligand for a proprietary gene therapy promoter system. It is also a moderate inhibitor of and substrate for CYP3A4/5.Formula:C27H38N2O3Purity:98%Color and Shape:SolidMolecular weight:438.6NSC23925
CAS:NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Formula:C22H26Cl2N2O2Purity:98%Color and Shape:SolidMolecular weight:421.3611β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS:Formula:C21H28O5Purity:98%Color and Shape:SolidMolecular weight:360.4440(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS:Formula:C24H31FO6Purity:99%Color and Shape:SolidMolecular weight:434.4977Ref: IN-DA0039HQ
Discontinued productRef: IN-DA0034OW
Discontinued product11β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS:Formula:C21H30O5Purity:98%Color and Shape:SolidMolecular weight:362.4599Ref: IN-DA003AAY
Discontinued product9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS:Formula:C22H29FO5Purity:99%Color and Shape:SolidMolecular weight:392.4611α-Terpineol
CAS:Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Formula:C10H18OPurity:97.55%Color and Shape:Colorless LiquidMolecular weight:154.25Tripeptide-41
CAS:Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.Formula:C29H30N4O5Purity:98%Color and Shape:SolidMolecular weight:514.57Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.Formula:C67H127F3N10O14SPurity:99.90%Color and Shape:SoildMolecular weight:1385.84Racemic Naproxen
CAS:Racemic Naproxen is a biochemical substance.Formula:C14H14O3Purity:98%Color and Shape:Crystals From Acetone-Hexane White SolidMolecular weight:230.26Xibornol
CAS:Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formula:C18H26OColor and Shape:SolidMolecular weight:258.4Ref: TM-T35177
Discontinued productDi-O-methyldemethoxycurcumin
CAS:Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.Formula:C22H22O5Purity:98%Color and Shape:SolidMolecular weight:366.412,3-Bis(3-indolylmethyl)indole
CAS:2,3-Bis(3-indolylmethyl)indole exhibits a concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption.Formula:C26H21N3Color and Shape:SolidMolecular weight:375.475RIDR-PI-103
CAS:RIDR-PI-103 is a reactive oxygen species (ROS)-induced drug release prodrug featuring an autocyclized portion connected to the pan-PI3K inhibitor (PI-103). In MDA-MB-361 and MDA-MB-231 cells, Doxorubicin and RIDR-PI-103 exhibited synergistic inhibition of cancer cell proliferation.Formula:C27H25N7O4Color and Shape:SolidMolecular weight:511.53Icatolimab
Icatolimab (JS-004) is a humanized antibody targeting BTLA/CD272 for the study of lymphomas and solid tumors.
Purity:98.7% (SDS-PAGE); 95.6% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.6% (SEC-HPLC)Color and Shape:LiquidMolecular weight:145.5 kDaRef: TM-T77490
Discontinued productgp91ds-tat
gp91ds-tat is a useful organic compound for research related to life sciences and the catalog number is T35393.
Purity:98%Color and Shape:SolidJH-X-119-01 hydrochloride
CAS:JH-X-119-01 hydrochloride is a potent, selective inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) that effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice.Formula:C25H21ClN6O3Color and Shape:SolidMolecular weight:488.93Elamipretide acetate
Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.
Formula:C34H53N9O7Purity:99.76%Color and Shape:SoildMolecular weight:699.84Ref: TM-TP1095L
Discontinued productTLQP-21 TFA
TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.
Purity:98%Color and Shape:LiquidTacalcitol
CAS:Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.Formula:C27H44O3Purity:98%Color and Shape:SolidMolecular weight:416.64STING agonist-22
CAS:STING agonist-22 (CF501) boosts vaccines by activating STING, inducing IFN-I and cytokines, aiding in SARS-CoV-2 research.
Formula:C40H48N14O6Color and Shape:SolidMolecular weight:820.9Aurothioglucose
CAS:Aurothioglucose is a active-site TrxR1 inhibitor.Formula:C6H11AuO5SPurity:98%Color and Shape:Yellow Crystals SolidMolecular weight:392.18Magnesium citrate
CAS:Magnesium citrate is a useful organic compound for research related to life sciences. The catalog number is T64455 and the CAS number is 3344-18-1.Formula:C12H10Mg3O14Color and Shape:SolidMolecular weight:451.113TLR7/8/9 antagonist 2
CAS:TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.Formula:C23H31N7Purity:98%Color and Shape:SoildMolecular weight:405.54Nogapendekin alfa inbakicept
CAS:Nogapendekin alfa inbakicept is an IL-15 superagonist that enhances anti-tumor immune responses by activating NK cells and T cells. It is being studied for use in non-muscle invasive bladder cancer (NMIBC).Color and Shape:SolidARGX-112
CAS:Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.
Color and Shape:Odour LiquidL-NIO dihydrochloride
CAS:L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.Formula:C7H16ClN3O2Purity:98%Color and Shape:SolidMolecular weight:209.67ALPK1-IN-1
CAS:ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.
Formula:C25H32N6O2SColor and Shape:SolidMolecular weight:480.63ALPK1-IN-2
CAS:ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).
Formula:C20H18F2N4O2SColor and Shape:SolidMolecular weight:416.44ALPK1-IN-3
CAS:ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced
Formula:C20H16F2N4OSPurity:98%Color and Shape:SolidMolecular weight:398.43
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