Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3044 products of "Immunology and Inflammation"
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RIPK1-IN-25
<p>RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.</p>Color and Shape:Odour SolidTGF-β/Smad Compound Library
<p>A unique collection of xnum TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;</p>Color and Shape:Odour SolidIACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Formula:C20H29FN12O9P2S2Color and Shape:SolidMolecular weight:726.6Mosnodenvir
CAS:<p>Mosnodenvir is a pan-DENV inhibitor effective against all four serotypes of dengue viruses, with the advantage of being highly potent and orally bioavailable, and blocks viral replication by inhibiting the formation of the complex between NS3 and NS4B.</p>Formula:C26H22ClF3N2O6SPurity:99.72%Color and Shape:SoildMolecular weight:582.98NLRP3-IN-48
<p>NLRP3-IN-48 is an inhibitor of NLRP3. It suppresses the activation of the NLRP3 inflammasome by targeting the NLRP3 protein, thereby interfering with the assembly of the NLRP3 inflammasome. Additionally, NLRP3-IN-48 exhibits anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>Color and Shape:Odour SolidAntiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Color and Shape:Odour SolidBMS-986179
<p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>Color and Shape:Odour LiquidNLRP3-IN-15
CAS:<p>NLRP3-IN-15: potent, selective NLRP3 inflammasome inhibitor; IC50 0.114 μM for IL-1β; for inflammation research.</p>Formula:C22H19NO4Color and Shape:SolidMolecular weight:361.394'-hydroxy Flurbiprofen
CAS:<p>4'-hydroxy Flurbiprofen can be used in related research in the field of life sciences. Its product number is T35722 and CAS number is 52807-12-2.</p>Formula:C15H13FO3Color and Shape:SolidMolecular weight:260.264NG-Hydroxy-L-arginine acetate
CAS:<p>NG-Hydroxy-L-arginine acetate (NOHA acetate) acts as a crucial physiological inhibitor of arginase, playing a vital role in the conversion of arginine to nitric oxide and citrulline via nitric oxide synthase.</p>Formula:C6H14N4O3xC2H4O2Color and Shape:SolidMolecular weight:190.20（free base）Antibacterial agent 119
<p>Antibacterialagent 119 (Compound 21 g) is a potential antibacterial agent effective against methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL against tested strains. It induces reactive oxygen species (ROS) generation and disrupts bacterial cell membranes, causing their rupture. Antibacterialagent 119 exhibits strong antimicrobial activity, low cytotoxicity, rapid bactericidal action, and favorable in vivo antibacterial efficacy.</p>Formula:C42H54BrClN2O4Color and Shape:SolidMolecular weight:766.246STING agonist-28
CAS:<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Formula:C39H46N14O6Color and Shape:SolidMolecular weight:806.87Butan-1-amine hydrochloride
CAS:<p>1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).</p>Formula:C4H12ClNColor and Shape:SolidMolecular weight:109.6AMY-101
CAS:<p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>Formula:C83H117N23O18S2Purity:98%Color and Shape:SolidMolecular weight:1789.11Ac-LDEETGEFL-NH2
CAS:<p>Ac-LDEETGEFL-NH2 is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor</p>Formula:C48H72N10O19Color and Shape:SolidMolecular weight:1093.14SMRT peptide
CAS:SMRT peptide, one of the corepressor factors interacting with the BCL6 BTB domain, binds to the BTB domain of BCL6 to enhance its transcriptional repression function. Additionally, SMRT peptide is utilized for studying protein-protein interactions.Formula:C82H142N26O24Color and Shape:SolidMolecular weight:1876.165(S),15(S)-DiHETE
CAS:<p>5(S),15(S)-DiHETE, made by 15-LO from 5(S)-HETE, boosts human PMNL degranulation via PAF, not fMLP/A23187/LTB4, and lures eosinophils at ED50 of 0.3μM.</p>Formula:C20H32O4Color and Shape:SolidMolecular weight:336.472iE-DAP dihydrochloride
<p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>Formula:C12H23Cl2N3O7Color and Shape:SolidMolecular weight:391.09131Avatrombopag hydrochloride
CAS:<p>Avatrombopag (AKR-501) - oral, nonpeptide TPO receptor agonist, EC50 3.3 nM, boosts platelet production, CYP2C9 and CYP3A substrate.</p>Color and Shape:SolidSirtuin modulator 2
CAS:<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>Formula:C19H15N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:349.41Ac-macropa
<p>Ac-macropa is a conjugate of Actinium-225 that targets PSMA, and it is useful for researching prostate cancer.</p>Formula:C39H52AcN6O9SMolecular weight:1007.3794OVA Peptide(257-264)
CAS:<p>OVA Peptide(257-264) is an ovalbumin octamer Peptide expressed by class I MHC molecule h-2kb.</p>Formula:C45H74N10O13Purity:99.53%Color and Shape:SolidMolecular weight:963.13Antidesmone
CAS:<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Formula:C19H29NO3Purity:98%Color and Shape:SolidMolecular weight:319.44FITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Color and Shape:Odour SolidIKK-IN-3
CAS:<p>IKK-IN-3: potent IKK2 inhibitor (IC50=19nM), affects IKK1(IC50=400nM).</p>Formula:C17H17N5SColor and Shape:SolidMolecular weight:323.42Guretolimod
CAS:<p>Guretolimod is a Toll-like receptor 7 (TLR7) agonist.</p>Formula:C24H34F3N5O4Color and Shape:SolidMolecular weight:513.562Allyl methyl trisulfide
CAS:<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Formula:C4H8S3Color and Shape:SolidMolecular weight:152.32-Isopropyl-1H-imidazole
CAS:<p>2-Isopropyl-1H-imidazole is a weak inhibitor of NO synthase and can be used in related research in the field of life sciences.</p>Formula:C6H10N2Purity:99.71%Color and Shape:SolidMolecular weight:110.16FITC-labeled ODN TTAGGG sodium
<p>FITC-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide that functions as an antagonist of TLR9, AIM2, and cGAS.</p>Color and Shape:Odour SolidPolyinosinic acid
CAS:<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Formula:(C10H13N4O8P)xColor and Shape:SolidGSK1795091
CAS:<p>GSK1795091, a synthetic TLR4 agonist, boosts immunity and shows antitumor effects, enhancing flu vaccine response.</p>Formula:C81H157N2O16PColor and Shape:SolidMolecular weight:1446.119Arginase inhibitor 7
CAS:<p>Arginase Inhibitor 7 (compound A17), an inhibitor of arginase (ARG1), exhibits an IC 50 value of 0.16 μM and possesses high oral bioavailability [1].</p>Formula:C14H29BN6O5Color and Shape:SolidMolecular weight:372.23MJ210
<p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>Color and Shape:Odour SolidMUC1, mucin core
CAS:<p>MUC1: Type I transmembrane glycoprotein, overexpressed and abnormally glycosylated in cancer, binds ICAM-1 domain 1.</p>Formula:C61H101N19O24Color and Shape:SolidMolecular weight:1484.588KYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Formula:C22H19FN6Purity:98.35%Color and Shape:SolidMolecular weight:386.43TLR4 agonist-1 TEA
<p>TLR4 agonist-1 (TEA, compound 17a) is a potent activator of Toll-like Receptor 4 (TLR4) and prompts the production of MIP-1β in RAW 264.7 and MM6 cells [1].</p>Color and Shape:Odour SolidMCI
<p>MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation</p>Formula:C45H52ClN7O13Purity:98%Color and Shape:SolidMolecular weight:934.39CAY10657
CAS:<p>CAY10657 has a wide range of applications in life science related research.</p>Formula:C17H20N4O3SColor and Shape:SolidMolecular weight:360.43HNGF6A
CAS:<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Formula:C112H198N34O31S2Purity:98%Color and Shape:SolidMolecular weight:2581.11cGAMP disodium
CAS:<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Formula:C20H24N10O13P2·2NaColor and Shape:SoildMolecular weight:720.39PSMA-IN-1
<p>PSMA-IN-1 (compound 23) is an inhibitor of PSMA with a Ki value of 2.49 nM. It inhibits tumor growth with high selectivity and specificity in PSMA+ tumor models. Additionally, PSMA-IN-1 serves as an NIR (λEX: 620 nm; λEM: 670 nm) dye for tumor imaging. PSMA-IN-1 is utilized in prostate cancer research.</p>Formula:C66H80N10O20Molecular weight:1332.55504Anti-osteoporosis agent-8
<p>Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.</p>Formula:C18H19F3N2O2SeMolecular weight:432.05638Phytoene desaturase-IN-1
CAS:<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Formula:C18H13ClF3N3O2SColor and Shape:SolidMolecular weight:427.83Phthalazine
CAS:<p>Compound PDK0135, with CAS No. 253-52-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0135 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C8H6N2Color and Shape:Yellow SolidMolecular weight:130.14Valeriandoid F
CAS:<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Formula:C23H34O9Color and Shape:SolidMolecular weight:454.516Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Formula:C27H33N3O2Purity:99.58% - 99.88%Color and Shape:SoildMolecular weight:431.57PSMA-trillium
CAS:<p>PSMA-trillium is a PSMA-targeting compound comprising a PSMA-targeting molecule (PSMA binding agent), a Macropa chelator, and a pharmacokinetics-modulating group (PK modulator). It acts as the non-radioactive variant of Actinium-225-PSMA-Trillium (BAY 3563254), boasting enhanced PSMA targeting and pharmacokinetic properties. PSMA-trillium can bind with Ac through either the Macropa chelator or the radioactive isotope Actinium-225. Actinium-225-PSMA-Trillium effectively inhibits metastatic castration-resistant prostate cancer (mCRPC).</p>Formula:C106H156IN17O34SMolecular weight:2371.44InsB (9-23)
CAS:<p>InsB (9-23) (InsulinB chain (9-23)) is an insulin B chain peptide capable of binding to the class II major histocompatibility complex (MHC) allele I-Ag7. It holds potential for research into various autoimmune diseases, including type 1 diabetes.</p>Formula:C72H116N20O22SMolecular weight:1645.88APF
CAS:<p>APF, a low-fluorescence probe, turns bright (490/515 nm) when oxidized by specific radicals; not affected by NO or H2O2.</p>Formula:C26H17NO5Color and Shape:SolidMolecular weight:423.426-Amyl-2-pyrone
CAS:<p>6-Amyl-2-pyrone exhibits inhibitory activity against tyrosinase, antibacterial and antiviral activity against Penicillium vulpinum and Aspergillus flavus, and antifungal activity against Sclerotinia sp.</p>Formula:C10H14O2Purity:99.00%Color and Shape:SolidMolecular weight:166.22
