Immunology and Inflammation
Immunology and inflammation inhibitors are compounds that modulate the immune response and inflammatory processes. These inhibitors are crucial in studying the mechanisms of immune regulation, autoimmunity, and chronic inflammation, as well as in developing treatments for inflammatory diseases, allergies, and immune-related disorders. By targeting key pathways in the immune system, these inhibitors can help reduce excessive or inappropriate immune responses. At CymitQuimica, we provide a comprehensive selection of high-quality immunology and inflammation inhibitors to support your research in immunology, inflammation, and therapeutic development.
Subcategories of "Immunology and Inflammation"
- CCR(136 products)
- CXCR(148 products)
- Cell wall(5 products)
- IL Receptor(112 products)
- IκB/IKK(60 products)
- LTR(3 products)
- MALT(23 products)
- MRP(6 products)
- NADPH-oxidase(1 products)
- NF-κB(444 products)
- NOD(17 products)
- NOS(63 products)
- Nrf2(78 products)
- PGE Synthase(31 products)
- ROS(69 products)
- TGF-beta/Smad(58 products)
- TLR(66 products)
- Thioredoxin(12 products)
- gp120/CD4(4 products)
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Found 3044 products of "Immunology and Inflammation"
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Valeriandoid F
CAS:<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Formula:C23H34O9Color and Shape:SolidMolecular weight:454.516Feeblin
CAS:<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Formula:C27H33N3O2Purity:99.58% - 99.88%Color and Shape:SoildMolecular weight:431.57STING agonist-17
CAS:<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formula:C43H53N13O8Color and Shape:SolidMolecular weight:879.96HPK1-IN-58
<p>HPK1-IN-58 is an inhibitor of HPK1 (IC50: 2.6 nM) and SLP76 (IC50: 20 nM). It enhances IL-2 secretion, thereby reversing PGE2-induced immunosuppression. HPK1-IN-58 is applicable for research in antitumor immunity.</p>Formula:C26H30N8OColor and Shape:SolidMolecular weight:470.25426Gp100 (25-33), human
CAS:<p>Gp100 (25-33), human: 9-AA melanoma antigen fragment, H-2Db restricted, T-cell recognized, targets B16 melanoma.</p>Formula:C52H82N16O14Purity:98%Color and Shape:SolidMolecular weight:1155.31COX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Formula:C27H26N6OS2Purity:98%Color and Shape:SolidMolecular weight:514.66Anti-IL11RA Antibody (X209)
<p>Anti-IL11RA Antibody (X209) is a human-derived IgG4, κ type antibody inhibitor targeting human IL-11RA.</p>Color and Shape:Odour LiquidPhotosensitizer-4
<p>Compound PS-I (Photosensitizer-4) is an effective photosensitizer that can efficiently kill cancer cells and inhibit tumor growth under light exposure.</p>Color and Shape:Odour SolidPROTAC STING Degrader-1
CAS:<p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>Formula:C34H33N7O10Color and Shape:SolidMolecular weight:699.67NF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formula:C16H11FN2O2SPurity:99.58%Color and Shape:SolidMolecular weight:314.33TLR8 agonist 8
CAS:<p>TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.</p>Formula:C53H63N11O10Color and Shape:SolidMolecular weight:1014.143-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
CAS:<p>3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).</p>Formula:C28H24ClN3O6Purity:99.9%Color and Shape:SolidMolecular weight:533.96STING-IN-6
CAS:<p>STING-IN-6 (compound 50), a potent inhibitor of STING, exhibits a pIC50 value of 8.9, indicating its significant inhibitory capacity.</p>Formula:C46H52N12O6Color and Shape:SolidMolecular weight:868.98Timosaponin E2
CAS:<p>Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].</p>Formula:C46H78O20Color and Shape:SolidMolecular weight:951.1DDX3-IN-1
CAS:DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity.Formula:C17H17N5OColor and Shape:SolidMolecular weight:307.35C6 L-threo Ceramide (d18:1/6:0)
CAS:<p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>Formula:C24H47NO3Color and Shape:SolidMolecular weight:397.63QX-005N
<p>QX 005N is a humanized monoclonal anti-CD124/IL4R/IL-4Rα antibody. It is applicable in research related to asthma.</p>Color and Shape:Odour Liquid[12]-Dehydrogingerdione
CAS:<p>[12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity.Cost-effective and quality-assured.</p>Formula:C23H34O4Purity:98%Color and Shape:SolidMolecular weight:374.51Aminopicoline
CAS:<p>Compound Fr16695, with CAS No. 695-34-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16695 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C6H8N2Color and Shape:White To Pale Yellow Solid FlakesMolecular weight:108.14CFT7455
CAS:<p>CFT7455: orally active anti-cancer drug, targets cereblon E3 ligase (Kd 0.9 nM), degrades IKZF1/Ikaros, IKZF3/Aiolos.</p>Formula:C28H27N3O4Purity:97.93%Color and Shape:SolidMolecular weight:469.53Mifamurtide sodium
CAS:<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Formula:C59H108N6NaO19PPurity:98%Color and Shape:SolidMolecular weight:1259.48c-di-AMP disodium
CAS:<p>c-di-AMP sodium: STING agonist, activates TBK3-IRF3 pathway, boosts type I IFN/TNF, regulates bacterial growth/virulence, and stimulates immune responses.</p>Formula:C20H22N10Na2O12P2Color and Shape:SolidMolecular weight:702.38PROTAC STING degrader-4
<p>PROTACSTING degrader-4 is a covalent STINGPROTAC degrader free of nitro groups, exhibiting a DC50 of 3.23 μM. It effectively inhibits STING and its downstream signaling pathways, including p-TBK1 and p-NF-κB (p-P65), as well as immune-inflammatory cytokines. Additionally, PROTACSTING degrader-4 mitigates renal and blood inflammation in mouse models of Cisplatin-induced acute kidney injury (AKI).</p>Formula:C39H42Cl2N8O9Color and Shape:SolidMolecular weight:836.24518AHR Inhibitor I-103
CAS:<p>AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.</p>Formula:C21H17FN6Purity:98.70%Color and Shape:SoildMolecular weight:372.4Eftilagimod alfa
CAS:<p>Eftilagimod alfa (IMP321), a recombinant LAG-3Ig fusion protein, binds to MHC class II and mediates the activation of antigen-presenting cells (APCs), which in</p>Color and Shape:LiquidPSMA-IN-3
<p>PSMA-IN-3 (compound 17) is a novel, high-affinity inhibitor of Prostate-Specific Membrane Antigen (PSMA) with an inhibitory concentration (IC50) of 13 nM,</p>Formula:C43H50FN7O15Color and Shape:SolidMolecular weight:923.89Cyclic-di-GMP disodium
CAS:<p>Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria.Cost-effective and quality-assured.</p>Formula:C20H22N10Na2O14P2Purity:98.98% - 99.93%Color and Shape:SolidMolecular weight:734.38Obinutuzumab
CAS:<p>Obinutuzumab (Obinutuzumab/afutuzumab) GA101) is a glycoengineered Type II CD20 monoclonal antibody in development for non-Hodgkin lymphoma.</p>Purity:98.00% - 98.9% (SDS-PAGE); 99.4% (SEC-HPLC)Color and Shape:LiquidMolecular weight:144.6 kDaNLRP3-IN-74
<p>NLRP3-IN-74 (Compound 11) is an orally active NLRP3 inhibitor with an IC50 of 2.7 μM. It significantly reduces IL-1β release by approximately 90% without affecting TNFα release. NLRP3-IN-74 is applicable in research on diseases such as atherosclerosis and Parkinson's disease.</p>Color and Shape:Odour SolidSTING-IN-13
<p>STING-IN-13 is a selective STING inhibitor that effectively suppresses downstream signaling of the STING pathway and STING-mediated inflammation. It exhibits low toxicity and is suitable for research related to STING-associated inflammatory and autoimmune diseases.</p>Color and Shape:Odour SolidHispaglabridin A
CAS:<p>Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1].</p>Formula:C25H28O4Color and Shape:SolidMolecular weight:392.49Cryogenine
CAS:<p>Cryogenine, from H. salicifolia, is an anti-inflammatory alkaloid, blocks prostaglandin synthetase, and alleviates rat arthritis.</p>Formula:C26H29NO5Color and Shape:SolidMolecular weight:435.52Antidesmone
CAS:<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Formula:C19H29NO3Purity:98%Color and Shape:SolidMolecular weight:319.44Ieramilimab
<p>Ieramilimab (LAG525) is a humanized antibody targeting LAG-3 with potential anticancer activity for the study of malignant tumors.</p>Purity:96.4% (SDS-PAGE); 97.8% (SEC-HPLC) - 96.4% (SDS-PAGE); 97.8% (SEC-HPLC)Color and Shape:Odour LiquidLY2409881
CAS:<p>LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.</p>Formula:C24H29ClN6OSColor and Shape:SolidMolecular weight:485.05TLR7 agonist 17
CAS:<p>TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].</p>Formula:C25H37N7O3Color and Shape:SolidMolecular weight:483.61ODN D-SL03
CAS:<p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.</p>Color and Shape:SolidMolecular weight:9345FM-303
<p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>Color and Shape:Odour LiquidSIN 14
<p>SIN 14 is an HO-1 activator that targets and activates HO-1 through an allosteric mechanism. Additionally, SIN 14 can induce the polarization of macrophages from the M1 phenotype to the M2 phenotype.</p>Formula:C20H22ClNO4Color and Shape:SolidMolecular weight:375.12374Tuparstobart
CAS:<p>Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on</p>Color and Shape:LiquidCAY10614
CAS:<p>CAY10614 is a TLR4 antagonist.</p>Formula:C42H78INO2Color and Shape:SolidMolecular weight:755.995Bavunalimab
CAS:<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Color and Shape:LiquidLadanetin-6-O-β-D-glucopyranoside
CAS:<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formula:C22H22O11Color and Shape:SolidMolecular weight:462.4Pam2CSK4
CAS:<p>TLR2/6 agonist; boosts TNF-α in human cells & mouse B cell growth/activation.</p>Formula:C65H126N10O12SPurity:98%Color and Shape:SolidMolecular weight:1271.83MethADP sodium salt
CAS:<p>MethADP is a specific CD73 inhibitor.</p>Formula:C11H17N5NaO9P2Purity:98%Color and Shape:SolidMolecular weight:448.223′-Hydroxy-4′-O-methylglabridin
CAS:<p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>Formula:C21H22O5Color and Shape:SolidMolecular weight:354.47-Deoxy-trans-dihydronarciclasine
CAS:<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Formula:C14H15NO6Color and Shape:SolidMolecular weight:293.27Glutathione ethyl ester acetate
<p>Glutathione ethyl ester acetate is an antioxidant and cell-permeable Glutathione (GSH) donor that restore oxidative stress and TGase up-regulation.</p>Formula:C14H25N3O8SPurity:97.49%Color and Shape:SolidMolecular weight:395.43MUC5AC motif peptide
<p>MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.</p>Formula:C63H104N16O26Purity:98%Color and Shape:SolidMolecular weight:1501.62His-Pro
CAS:<p>His-Pro is a dipeptide consisting of histidyl and proline.</p>Formula:C11H16N4O3Purity:98%Color and Shape:SolidMolecular weight:252.27
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